Publications






Impact of Advanced Age on Survival in Patients Undergoing Resection of Hepatocellular Carcinoma: Report of a Japanese Nationwide Survey.
Ann Surg 2017 Sep 15. Epub 2017 Sep 15.
*Department of Surgery, Hirakata Hospital, Kansai Medical University, Hirakata, Osaka, Japan †Department of Mathematics and Statistics in Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan ‡Department of Biostatistics, Kyoto Prefectural University of Medicine, Kyoto, Japan §Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan ¶Department of Medical Oncology, Kyorin University School of Medicine, Tokyo, Japan ||Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan **Department of Gastroenterology, Musashino Red Cross Hospital, Tokyo, Japan ††Department of Radiology, Shinshu University School of Medicine, Matsumoto, Japan ‡‡Department of Gastroenterology and Hepatology, Kinki University School of Medicine, Osaka, Japan §§Department of Gastroenterology, Ogaki Municipal Hospital, Ogaki, Japan ¶¶Department of Pathology, Keio University School of Medicine, Tokyo, Japan ||||Department of Clinical Laboratory Medicine, Kurume University Hospital, Kurume, Japan ***Department of Biostatics, School of Public Health University of Tokyo, Tokyo, Japan †††Department of Digestive Surgery, Nihon University School of Medicine, Tokyo, Japan ‡‡‡National Center for Global Health and Medicine, Tokyo, Japan.

Liver resection for hepatocellular carcinoma associated with hepatic vein invasion: A Japanese nationwide survey.
Hepatology 2017 Aug 26;66(2):510-517. Epub 2017 Jun 26.
Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.


The PD-1/PD-L1 axis may be aberrantly activated in occupational cholangiocarcinoma.
Pathol Int 2017 Mar 31;67(3):163-170. Epub 2017 Jan 31.
Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.



Surgical Outcomes for the Ruptured Hepatocellular Carcinoma: Multicenter Analysis with a Case-Controlled Study.
J Gastrointest Surg 2016 Dec 7;20(12):2021-2034. Epub 2016 Oct 7.
Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abenoku, Osaka, 545-8585, Japan.


Hypermutation and unique mutational signatures of occupational cholangiocarcinoma in printing workers exposed to haloalkanes.
Carcinogenesis 2016 Aug 7;37(8):817-826. Epub 2016 Jun 7.
Division of Translational Research, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan.

Relationship between cumulative exposure to 1,2-dichloropropane and incidence risk of cholangiocarcinoma among offset printing workers.
Occup Environ Med 2016 Aug 1;73(8):545-52. Epub 2016 Jul 1.
Department of Preventive Medicine and Environmental Health, Osaka City University Graduate School of Medicine, Osaka, Japan Ohara Memorial Institute for Science of Labor, Tokyo, Japan.


Comparison of clinicopathological characteristics between patients with occupational and non-occupational intrahepatic cholangiocarcinoma.
J Hepatobiliary Pancreat Sci 2016 Jul 3;23(7):389-96. Epub 2016 May 3.
Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.

Screening and surveillance for occupational cholangiocarcinoma in workers exposed to organic solvents.
Surg Today 2016 Jun 31;46(6):705-12. Epub 2015 Jul 31.
Department of Occupational and Environmental Management, University of Occupational and Environmental Health, Kitakyushu, Japan.

The association between non-alcoholic steatohepatitis and intrahepatic cholangiocarcinoma: A hospital based case-control study.
J Surg Oncol 2016 Jun 21;113(7):779-83. Epub 2016 Mar 21.
Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Asahimachi, Abenoku, Osaka, Japan.






Response Evaluation Criteria in Cancer of the Liver (RECICL) (2015 Revised version).
Hepatol Res 2016 Jan 4;46(1):3-9. Epub 2015 Aug 4.
Committee for Response Evaluation Criteria in Cancer of the Liver, Liver Cancer Study Group of Japan, Department of Gastroenterology and Hepatology, Kinki University School of Medicine, Osaka-Sayama, Japan.

Outcomes of Pure Laparoscopic versus Open Hepatic Resection for Hepatocellular Carcinoma in Cirrhotic Patients: A Case-Control Study with Propensity Score Matching.
Eur Surg Res 2015 Dec 23;55(4):291-301. Epub 2015 Sep 23.
Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.


Hepatic resection for hepatocellular carcinoma in super-elderly patients aged 80 years and older in the first decade of the 21st century.
Surg Today 2015 Jul 13;45(7):851-7. Epub 2014 Aug 13.
Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan,

Management of hepatitis B virus infection during treatment for hepatitis B virus-related hepatocellular carcinoma.
World J Gastroenterol 2015 Jul;21(27):8249-55
Shoji Kubo, Shigekazu Takemura, Shogo Tanaka, Hiroji Shinkawa, Takayoshi Nishioka, Akinori Nozawa, Masahiko Kinoshita, Genya Hamano, Tokuji Ito, Yorihisa Urata, Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka 545-8585, Japan.

Therapeutic administration of an ingredient of aged-garlic extracts, S-allyl cysteine resolves liver fibrosis established by carbon tetrachloride in rats.
J Clin Biochem Nutr 2015 May 28;56(3):179-85. Epub 2015 Mar 28.
Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Osaka City University, Abeno-ku, Osaka 545-8585, Japan ; Food Hygiene and Environmental Health Division of Applied Life Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Sakyo-ku, Kyoto 602-8522, Japan.


A multi-institution phase II study of gemcitabine/cisplatin/S-1 (GCS) combination chemotherapy for patients with advanced biliary tract cancer (KHBO 1002).
Cancer Chemother Pharmacol 2015 Feb 5;75(2):293-300. Epub 2014 Dec 5.
Department of Clinical Oncology and Pharmacogenomics, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan,











S-Allyl cysteine improves nonalcoholic fatty liver disease in type 2 diabetes Otsuka Long-Evans Tokushima Fatty rats via regulation of hepatic lipogenesis and glucose metabolism.
J Clin Biochem Nutr 2013 Sep 31;53(2):94-101. Epub 2013 Aug 31.
Department of Second Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8558, Japan.



Nutritional risk index as an independent predictive factor for the development of surgical site infection after pancreaticoduodenectomy.
Surg Today 2013 Mar 28;43(3):276-83. Epub 2012 Sep 28.
Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan.



Effects of antiviral therapy on long-term outcome after liver resection for hepatitis B virus-related hepatocellular carcinoma.
J Hepatobiliary Pancreat Sci 2012 Nov;19(6):685-96
Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan.

Effect of interferon therapy on first and second recurrence after resection of hepatitis C virus-related hepatocellular carcinoma.
Hepatol Res 2012 Jun 18;42(6):564-73. Epub 2012 Jan 18.
Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine Department of Hepato-Biliary-Pancreatic Surgery, Osaka City General Hospital Department of Surgery, Osaka City Juso Hospital, Osaka, Japan.




A case of intrahepatic cholangiocarcinoma detected after successful interferon therapy for chronic hepatitis C.
Clin J Gastroenterol 2010 Feb 3;3(1):45-9. Epub 2009 Dec 3.
Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan.


Development of a miR-26 companion diagnostic test for adjuvant interferon-alpha therapy in hepatocellular carcinoma.
Int J Biol Sci 2013 16;9(3):303-12. Epub 2013 Mar 16.
Liver Carcinogenesis Section, Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.

Different carcinogenic process in cholangiocarcinoma cases epidemically developing among workers of a printing company in Japan.
Int J Clin Exp Pathol 2014 15;7(8):4745-54. Epub 2014 Jul 15.
Department of Human Pathology, Kanazawa University Graduate School of Medicine Kanazawa, Japan ; Department of Pathology, Shizuoka Cancer Center Shizuoka, Japan.



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