Publications by authors named "Shobbir Hussain"

28Publications

Sequence- and structure-specific cytosine-5 mRNA methylation by NSUN6.

Authors:
Tommaso Selmi Shobbir Hussain Sabine Dietmann Matthias Heiß Kayla Borland Sophia Flad Jean-Michel Carter Rebecca Dennison Ya-Lin Huang Stefanie Kellner Susanne Bornelöv Michaela Frye

Nucleic Acids Res 2021 01;49(2):1006-1022

German Cancer Research Center - Deutsches Krebsforschungszentrum (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

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January 2021

On a New Proposed Mechanism of 5-Fluorouracil-Mediated Cytotoxicity.

Authors:
Shobbir Hussain

Trends Cancer 2020 05 13;6(5):365-368. Epub 2020 Mar 13.

Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, UK. Electronic address:

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May 2020

A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes.

Authors:
Charlotte Soneson Yao Yao Anna Bratus-Neuenschwander Andrea Patrignani Mark D Robinson Shobbir Hussain

Nat Commun 2019 07 31;10(1):3359. Epub 2019 Jul 31.

Department of Biology and Biochemistry, University of Bath, Bath, BA2 7AY, UK.

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July 2019

FICC-Seq: a method for enzyme-specified profiling of methyl-5-uridine in cellular RNA.

Authors:
Jean-Michel Carter Warren Emmett Igor Rdl Mozos Annika Kotter Mark Helm Jernej Ule Shobbir Hussain

Nucleic Acids Res 2019 11;47(19):e113

Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK.

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November 2019

A junction coverage compatibility score to quantify the reliability of transcript abundance estimates and annotation catalogs.

Authors:
Charlotte Soneson Michael I Love Rob Patro Shobbir Hussain Dheeraj Malhotra Mark D Robinson

Life Sci Alliance 2019 02 17;2(1). Epub 2019 Jan 17.

Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland

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February 2019

Catalytic crosslinking-based methods for enzyme-specified profiling of RNA ribonucleotide modifications.

Authors:
Shobbir Hussain

Methods 2019 03 9;156:60-65. Epub 2018 Oct 9.

Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom. Electronic address:

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March 2019

Native RNA-Sequencing Throws its Hat into the Transcriptomics Ring.

Authors:
Shobbir Hussain

Trends Biochem Sci 2018 04 1;43(4):225-227. Epub 2018 Mar 1.

Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK. Electronic address:

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April 2018

Shaping and Reshaping Transcriptome Plasticity during Evolution.

Authors:
Shobbir Hussain

Trends Biochem Sci 2017 09 14;42(9):682-684. Epub 2017 Jul 14.

Department of Biology and Biochemistry, University of Bath, Bath, BA2 7AY, UK. Electronic address:

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September 2017

Robust long-read native DNA sequencing using the ONT CsgG Nanopore system.

Authors:
Jean-Michel Carter Shobbir Hussain

Wellcome Open Res 2017 Apr 6;2:23. Epub 2017 Apr 6.

Department of Biology and Biochemistry, University of Bath, Bath, BA2 7AY, UK.

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April 2017

Illustrating the Epitranscriptome at Nucleotide Resolution Using Methylation-iCLIP (miCLIP).

Authors:
Harry George Jernej Ule Shobbir Hussain

Methods Mol Biol 2017 ;1562:91-106

Department of Biology and Biochemistry, University of Bath, Bath, BA2 7AY, UK.

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February 2018

Deficient methylation and formylation of mt-tRNA(Met) wobble cytosine in a patient carrying mutations in NSUN3.

Authors:
Lindsey Van Haute Sabine Dietmann Laura Kremer Shobbir Hussain Sarah F Pearce Christopher A Powell Joanna Rorbach Rebecca Lantaff Sandra Blanco Sascha Sauer Urania Kotzaeridou Georg F Hoffmann Yasin Memari Anja Kolb-Kokocinski Richard Durbin Johannes A Mayr Michaela Frye Holger Prokisch Michal Minczuk

Nat Commun 2016 06 30;7:12039. Epub 2016 Jun 30.

MRC Mitochondrial Biology Unit, Hills Road, Cambridge CB2 0XY, UK.

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June 2016

Stem cell function and stress response are controlled by protein synthesis.

Authors:
Sandra Blanco Roberto Bandiera Martyna Popis Shobbir Hussain Patrick Lombard Jelena Aleksic Abdulrahim Sajini Hinal Tanna Rosana Cortés-Garrido Nikoletta Gkatza Sabine Dietmann Michaela Frye

Nature 2016 06;534(7607):335-40

Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, Department of Genetics, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK.

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June 2016

A new conceptual framework for investigating complex genetic disease.

Authors:
Shobbir Hussain

Front Genet 2015 4;6:327. Epub 2015 Nov 4.

Department of Biology and Biochemistry, University of Bath Bath, UK.

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November 2015

The epitranscriptome in modulating spatiotemporal RNA translation in neuronal post-synaptic function.

Authors:
Shobbir Hussain Zafar I Bashir

Front Cell Neurosci 2015 31;9:420. Epub 2015 Oct 31.

School of Physiology and Pharmacology, University of Bristol Bristol, UK.

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November 2015

Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders.

Authors:
Sandra Blanco Sabine Dietmann Joana V Flores Shobbir Hussain Claudia Kutter Peter Humphreys Margus Lukk Patrick Lombard Lucas Treps Martyna Popis Stefanie Kellner Sabine M Hölter Lillian Garrett Wolfgang Wurst Lore Becker Thomas Klopstock Helmut Fuchs Valerie Gailus-Durner Martin Hrabĕ de Angelis Ragnhildur T Káradóttir Mark Helm Jernej Ule Joseph G Gleeson Duncan T Odom Michaela Frye

EMBO J 2014 Sep 25;33(18):2020-39. Epub 2014 Jul 25.

Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK

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September 2014

Developing a PPI inhibitor-based therapy for STXBP1 haploinsufficiency-associated epileptic disorders.

Authors:
Shobbir Hussain

Front Mol Neurosci 2014 4;7. Epub 2014 Feb 4.

Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute, University of Cambridge Cambridge, UK ; Department of Physiology, Development and Neuroscience, University of Cambridge Cambridge, UK.

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February 2014

Characterizing 5-methylcytosine in the mammalian epitranscriptome.

Authors:
Shobbir Hussain Jelena Aleksic Sandra Blanco Sabine Dietmann Michaela Frye

Genome Biol 2013 Nov 29;14(11):215. Epub 2013 Nov 29.

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November 2013

NSun2-mediated cytosine-5 methylation of vault noncoding RNA determines its processing into regulatory small RNAs.

Authors:
Shobbir Hussain Abdulrahim A Sajini Sandra Blanco Sabine Dietmann Patrick Lombard Yoichiro Sugimoto Maike Paramor Joseph G Gleeson Duncan T Odom Jernej Ule Michaela Frye

Cell Rep 2013 Jul 18;4(2):255-61. Epub 2013 Jul 18.

Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QR, UK.

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July 2013

The mouse cytosine-5 RNA methyltransferase NSun2 is a component of the chromatoid body and required for testis differentiation.

Authors:
Shobbir Hussain Francesca Tuorto Suraj Menon Sandra Blanco Claire Cox Joana V Flores Stephen Watt Nobuaki R Kudo Frank Lyko Michaela Frye

Mol Cell Biol 2013 Apr 11;33(8):1561-70. Epub 2013 Feb 11.

Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.

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April 2013

Analysis of CLIP and iCLIP methods for nucleotide-resolution studies of protein-RNA interactions.

Authors:
Yoichiro Sugimoto Julian König Shobbir Hussain Blaž Zupan Tomaž Curk Michaela Frye Jernej Ule

Genome Biol 2012 Aug 3;13(8):R67. Epub 2012 Aug 3.

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August 2012