Dr. Sho Morioka, PhD - University of Virginia - Research Scientist (Senior professional research staff)

Dr. Sho Morioka

PhD

University of Virginia

Research Scientist (Senior professional research staff)

Charlottesville, VA | United States

Main Specialties: Biology

Additional Specialties: Molecular Cloning, Signaling pathways, Phagocytosis, Vascular biology, Metabolism, Mouse Model Design, and advanced Cell Culture


Top Author

Dr. Sho Morioka, PhD - University of Virginia - Research Scientist (Senior professional research staff)

Dr. Sho Morioka

PhD

Introduction

Research professional with a B.S., M.S. and Ph.D. from Nagoya University (Academic Ranking of World Universities in Sciences 2017 3rd in Japan). Demonstrated ability in leadership of small groups and independent scientific investigation. Highly skilled in Molecular Cloning, Signaling pathways, Phagocytosis, Vascular biology, Metabolism, Mouse Model Design, and advanced Cell Culture

Primary Affiliation: University of Virginia - Charlottesville, VA , United States

Specialties:

Additional Specialties:

Research Interests:

Education

Mar 2017
University of Virginia
Research Scientist
Kodi Ravichandran lab
Jun 2014
University of Virginia
Research Associate
Kodi Ravichandran lab
May 2012
NCSU
Postdoctoral Fellow
Ninomiya Tsuji lab
Mar 2012
Nagoya University
Ph.D
Biological Science Kunihiro Matsumoto lab
Mar 2009
Nagoya University
M.S.
Biological Science Kunihiro Matsumoto lab
Mar 2007
Nagoya University
B.S.
Biological Science

Experience

Nov 2018
Yamada Research Grant
Feb 2018
Overseas Research Award from KANAE Foundation for the Promotion of Medical Science
Sep 2017
Scientific Reports
Editorial Board
Aug 2017
Scientific Reports
Invited reviewer
Jul 2017
PLOS ONE
Invited reviewer
Jul 2017
Osteoporosis International
Invited reviewer
Jul 2017
Marine Drugs
Invited reviewer
Jul 2017
JSM Biotechnology and Biomedical Engineering
Invited reviewer
Jul 2017
Cellular Physiology and Biochemistry
Invited reviewer
Jul 2017
Biochemical Pharmacology
Invited reviewer
Jul 2017
BioEssays
Invited reviewer
Jun 2017
PLOS ONE
Invited reviewer
Jun 2017
Mishima Kaiun Memorial Foundation Award
Jun 2017
Scientific Reports
Invited reviewer
Jun 2017
Cancers
Invited reviewer
Jun 2017
Annals of Allergy, Asthma
Invited reviewer
May 2017
Pilot projects from NIEHS funded P30 Center
Invited Grant Reviewer
May 2017
American Journal of Rhinology
Invited reviewer
May 2017
Kidney International
Invited reviewer
May 2017
Journal of American Society of Nephrology
Invited reviewer
May 2017
University of Virginia, MIC-CIC retreat
University of Virginia, MIC-CIC travel grant organizer: Budget, review and announcement
Mar 2017
Symposium for Advocates of Women in Science and Medicine (Navigating a job search for graduate students)
Invited Panel discussion leading researcher
Jan 2017
PLOS ONE
Invited reviewer
Oct 2016
Selected as a reserve for Astellas Pharma research abroad award
Oct 2016
Selected for JSPS Fellowship for Research Abroad
May 2015
University of Virginia Dept. of Microbiology, Immunology and Cancer biology Postdoctoral Award
Dec 2014
The German Israeli Foundation for Scientific Research and Development (GIF), Application For Research Grant Young Scientists Program
Invited Grant Reviewer
Mar 2013
Nagoya University Leading Program at North Carolina State University (Enriching experience for graduate students – to learn about innovation for research science
Invited Panel discussion leading researcher
Mar 2012
Keystone National Institute of Neurological Disorders and Stroke (NINDS) Award
Oct 2010
JSPS Excellent Young Researcher Overseas Fellowship
Apr 2009
Japan Society for the Promotion of Science (JSPS) Research Fellowship
Apr 2008
ASBMB graduate/Postdoc Travel Award

Publications

15Publications

239Reads

1507Profile Views

185PubMed Central Citations

Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release.

Authors:
Sho Morioka Justin S A Perry Michael H Raymond Christopher B Medina Yunlu Zhu Liyang Zhao Vlad Serbulea Suna Onengut-Gumuscu Norbert Leitinger Sarah Kucenas Jeffrey C Rathmell Liza Makowski Kodi S Ravichandran

Nature 2018 11 21;563(7733):714-718. Epub 2018 Nov 21.

The Center for Cell Clearance, University of Virginia, Charlottesville, VA, USA.

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http://dx.doi.org/10.1038/s41586-018-0735-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331005PMC
November 2018
33 Reads
42.351 Impact Factor

CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer.

Authors:
Alex D Michaels Timothy E Newhook Sara J Adair Sho Morioka Bernadette J Goudreau Sarbajeet Nagdas Matthew G Mullen Jesse B Persily Timothy N J Bullock Craig L Slingluff Kodi S Ravichandran J Thomas Parsons Todd W Bauer

Clin Cancer Res 2018 Mar 29;24(6):1415-1425. Epub 2017 Dec 29.

Department of Surgery, University of Virginia Health System, Charlottesville, Virginia.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-2283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296745PMC
March 2018
28 Reads
8.722 Impact Factor

Transforming growth factor-β-activated kinase 1 pathway

Authors:
Sho Morioka

Encyclopedia of Signaling Molecules, 2nd edition. New York, Springer

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December 2017
8 Reads

Noncanonical cell death program independent of caspase activation cascade and necroptotic modules is elicited by loss of TGFβ-activated kinase 1.

Authors:
September R Mihaly Yosuke Sakamachi Jun Ninomiya-Tsuji Sho Morioka

Sci Rep 2017 06 7;7(1):2918. Epub 2017 Jun 7.

Department of Biological Sciences, North Carolina State University, Raleigh, NC, 27695-7633, USA.

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http://dx.doi.org/10.1038/s41598-017-03112-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462742PMC
June 2017
23 Reads
1 Citation
5.080 Impact Factor

TAK1 regulates resident macrophages by protecting lysosomal integrity.

Authors:
Yosuke Sakamachi Sho Morioka September R Mihaly Giichi Takaesu Julie F Foley Michael B Fessler Jun Ninomiya-Tsuji

Cell Death Dis 2017 02 9;8(2):e2598. Epub 2017 Feb 9.

Department of Biological Sciences, North Carolina State University, Raleigh, NC 27695-7633, USA.

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http://dx.doi.org/10.1038/cddis.2017.23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386472PMC
February 2017
6 Reads
3 Citations
5.014 Impact Factor

TAK1 regulates hepatic lipid homeostasis through SREBP.

Authors:
S Morioka K Sai E Omori Y Ikeda K Matsumoto J Ninomiya-Tsuji

Oncogene 2016 07 14;35(29):3829-38. Epub 2016 Mar 14.

Department of Biological Sciences, North Carolina State University, Raleigh, NC, USA.

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http://dx.doi.org/10.1038/onc.2015.453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956508PMC
July 2016
25 Reads
4 Citations
8.460 Impact Factor

TAK1 determines susceptibility to endoplasmic reticulum stress and leptin resistance in the hypothalamus.

Authors:
Kazuhito Sai Sho Morioka Giichi Takaesu Nagendran Muthusamy H Troy Ghashghaei Hiroshi Hanafusa Kunihiro Matsumoto Jun Ninomiya-Tsuji

J Cell Sci 2016 05 16;129(9):1855-65. Epub 2016 Mar 16.

Department of Biological Sciences, North Carolina State University, Raleigh, NC 27695-7633, USA

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http://dx.doi.org/10.1242/jcs.180505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893799PMC
May 2016
14 Reads
3 Citations
5.432 Impact Factor

Activated macrophage survival is coordinated by TAK1 binding proteins.

Authors:
September R Mihaly Sho Morioka Jun Ninomiya-Tsuji Giichi Takaesu

PLoS One 2014 15;9(4):e94982. Epub 2014 Apr 15.

Department of Biological Sciences, Environmental and Molecular Toxicology, North Carolina State University, Raleigh, North Carolina, United States of America; Center for Integrated Medical Research, Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0094982PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988229PMC
January 2015
5 Reads
9 Citations
3.234 Impact Factor

TAK1 control of cell death.

Authors:
S R Mihaly J Ninomiya-Tsuji S Morioka

Cell Death Differ 2014 Nov 22;21(11):1667-76. Epub 2014 Aug 22.

Department of Biological Sciences, North Carolina State University, Environmental and Molecular Toxicology, Raleigh, NC 27695-7633, USA.

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http://dx.doi.org/10.1038/cdd.2014.123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211365PMC
November 2014
14 Reads
43 Citations
8.184 Impact Factor

TAK1 binding protein 2 is essential for liver protection from stressors.

Authors:
Yuka Ikeda Sho Morioka Kunihiro Matsumoto Jun Ninomiya-Tsuji

PLoS One 2014 3;9(2):e88037. Epub 2014 Feb 3.

Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088037PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912198PMC
October 2014
6 Reads
3 Citations
3.234 Impact Factor

TAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation.

Authors:
Sho Morioka Peter Broglie Emily Omori Yuka Ikeda Giichi Takaesu Kunihiro Matsumoto Jun Ninomiya-Tsuji

J Cell Biol 2014 Feb;204(4):607-23

Department of Biological Sciences, North Carolina State University, Raleigh, NC 27695.

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http://dx.doi.org/10.1083/jcb.201305070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926964PMC
February 2014
59 Reads
35 Citations
9.834 Impact Factor

TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration.

Authors:
Sho Morioka Maiko Inagaki Yoshihiro Komatsu Yuji Mishina Kunihiro Matsumoto Jun Ninomiya-Tsuji

Blood 2012 Nov 12;120(18):3846-57. Epub 2012 Sep 12.

Department of Molecular Biology, Graduate School of Science, Nagoya University, Nagoya, Japan.

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http://dx.doi.org/10.1182/blood-2012-03-416198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488895PMC
November 2012
7 Reads
20 Citations
10.452 Impact Factor

TAK1 kinase determines TRAIL sensitivity by modulating reactive oxygen species and cIAP.

Authors:
S Morioka E Omori T Kajino R Kajino-Sakamoto K Matsumoto J Ninomiya-Tsuji

Oncogene 2009 Jun 4;28(23):2257-65. Epub 2009 May 4.

Department of Molecular Biology, Nagoya University, Japan.

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http://dx.doi.org/10.1038/onc.2009.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796077PMC
June 2009
8 Reads
16 Citations
8.460 Impact Factor

TAK1 regulates reactive oxygen species and cell death in keratinocytes, which is essential for skin integrity.

Authors:
Emily Omori Sho Morioka Kunihiro Matsumoto Jun Ninomiya-Tsuji

J Biol Chem 2008 Sep 7;283(38):26161-8. Epub 2008 Jul 7.

Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, North Carolina 27695-7633, USA.

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http://dx.doi.org/10.1074/jbc.M804513200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533783PMC
September 2008
11 Reads
48 Citations
4.573 Impact Factor

Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release

Authors:
Sho Morioka Justin S. A. Perry Michael H. Raymond Christopher B. Medina Yunlu Zhu Liyang Zhao Vlad Serbulea Suna Onengut-Gumuscu Norbert Leitinger Sarah Kucenas Jeffrey C. Rathmell Liza Makowski and Kodi S. Ravichandran

Nature

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72 Reads

Top co-authors

Jun Ninomiya-Tsuji
Jun Ninomiya-Tsuji

8
Kunihiro Matsumoto
Kunihiro Matsumoto

Graduate School of Science

5
Giichi Takaesu
Giichi Takaesu

North Carolina State University

4
September R Mihaly
September R Mihaly

North Carolina State University

3
Emily Omori
Emily Omori

North Carolina State University

2
Yuka Ikeda
Yuka Ikeda

Wakayama Medical Center

2
Kodi S Ravichandran
Kodi S Ravichandran

University of Virginia

2
Yosuke Sakamachi
Yosuke Sakamachi

North Carolina State University

2
Nagendran Muthusamy
Nagendran Muthusamy

College of Veterinary Medicine

1
Kazuhito Sai
Kazuhito Sai

Graduate School of Science

1
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