Shiva Kumar Shanmukhappa

Shiva Kumar Shanmukhappa

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Shiva Kumar Shanmukhappa

Shiva Kumar Shanmukhappa

Publications by authors named "Shiva Kumar Shanmukhappa"

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13Publications

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αKlotho Regulates Age-Associated Vascular Calcification and Lifespan in Zebrafish.

Cell Rep 2019 Sep;28(11):2767-2776.e5

Zebrafish Group, Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, 181 Massachusetts Avenue, Cambridge, MA 02139, USA; Age-Related Disorders Group, Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, 181 Massachusetts Avenue, Cambridge, MA 02139, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.08.013DOI Listing
September 2019

Angiotensin receptor signaling in sickle cell anemia has a reno-protective effect on urine concentrating ability but results in sickle glomerulopathy.

Am J Hematol 2018 07 15;93(7):E177-E181. Epub 2018 May 15.

Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Research Foundation, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 45229.

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http://dx.doi.org/10.1002/ajh.25118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037553PMC
July 2018

Toll-Like Receptor 4-Independent Carbon Tetrachloride-Induced Fibrosis and Lipopolysaccharide-Induced Acute Liver Injury in Mice: Role of Hepatic Stellate Cells.

Am J Pathol 2017 Jun 13;187(6):1356-1367. Epub 2017 Apr 13.

Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Cincinnati VA Medical Center, Cincinnati, Ohio; Department of Surgery, University of Cincinnati, Cincinnati, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.01.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455062PMC
June 2017

Sickle cell anemia mice develop a unique cardiomyopathy with restrictive physiology.

Proc Natl Acad Sci U S A 2016 08 8;113(35):E5182-91. Epub 2016 Aug 8.

Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229; Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229;

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http://dx.doi.org/10.1073/pnas.1600311113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024607PMC
August 2016

Genetic diminution of circulating prothrombin ameliorates multiorgan pathologies in sickle cell disease mice.

Blood 2015 Oct 18;126(15):1844-55. Epub 2015 Aug 18.

Division of Experimental Hematology and Cancer Biology, Division of Hematology, Cancer and Blood Diseases Institute, and.

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http://dx.doi.org/10.1182/blood-2015-01-625707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600020PMC
October 2015

IgG1 protects against renal disease in a mouse model of cryoglobulinaemia.

Nature 2015 Jan 2;517(7535):501-4. Epub 2014 Nov 2.

1] Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA [2] Division of Immunology, Allergy and Rheumatology, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA [3] Medical Service, Cincinnati Veterans Affairs Medical Center, Cincinnati, Ohio 45220, USA.

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http://dx.doi.org/10.1038/nature13868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342786PMC
January 2015