Shirley H J Mei

Shirley H J Mei

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Shirley H J Mei

Shirley H J Mei

Publications by authors named "Shirley H J Mei"

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21Publications

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High circulating angiopoietin-2 levels exacerbate pulmonary inflammation but not vascular leak or mortality in endotoxin-induced lung injury in mice.

Thorax 2018 03 25;73(3):248-261. Epub 2017 Sep 25.

Regenerative Medicine Program, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1136/thoraxjnl-2017-210413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870448PMC
March 2018

Advances in Stem Cell and Cell-Based Gene Therapy Approaches for Experimental Acute Lung Injury: A Review of Preclinical Studies.

Hum Gene Ther 2016 10;27(10):802-812

1 Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1089/hum.2016.063DOI Listing
October 2016

Occlusive lung arterial lesions in endothelial-targeted, fas-induced apoptosis transgenic mice.

Am J Respir Cell Mol Biol 2015 Nov;53(5):712-8

1 Sinclair Centre for Regenerative Medicine, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1165/rcmb.2014-0311OCDOI Listing
November 2015

The Immunomodulatory and Therapeutic Effects of Mesenchymal Stromal Cells for Acute Lung Injury and Sepsis.

J Cell Physiol 2015 Nov;230(11):2606-17

Sinclair Centre for Regenerative Medicine, Ottawa Hospital Research Institute, Ottawa, Ontario.

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http://dx.doi.org/10.1002/jcp.25028DOI Listing
November 2015

Effects of mesenchymal stem cell therapy on the time course of pulmonary remodeling depend on the etiology of lung injury in mice.

Crit Care Med 2013 Nov;41(11):e319-33

1Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. 2Laboratory of Cellular and Molecular Physiology, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. 3The Keenan Research Centre of the Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, ON, Canada. 4Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON, Canada. 5Laboratory of Cellular and Molecular Cardiology, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. 6Laboratory of Inflammation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. 7The Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada.

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http://dx.doi.org/10.1097/CCM.0b013e31828a663eDOI Listing
November 2013

Targeted delivery of genes to endothelial cells and cell- and gene-based therapy in pulmonary vascular diseases.

Compr Physiol 2013 Oct;3(4):1749-79

Sprott Centre for Stem Cell Research, The Ottawa Hospital Research Institute and University of Ottawa, Ottawa, Ontario, Canada.

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http://doi.wiley.com/10.1002/cphy.c120034
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http://dx.doi.org/10.1002/cphy.c120034DOI Listing
October 2013

Tie2-dependent neovascularization of the ischemic hindlimb is mediated by angiopoietin-2.

PLoS One 2012 25;7(9):e43568. Epub 2012 Sep 25.

Terrence Donnelly Research Laboratories, Division of Cardiology, St. Michael's Hospital, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0043568PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458045PMC
April 2013

Network analysis of transcriptional responses induced by mesenchymal stem cell treatment of experimental sepsis.

Am J Pathol 2012 Nov;181(5):1681-92

Interdepartmental Division of Critical Care, The Keenan Research Centre of the Li Ka Shing Knowledge Institute of St. Michael's Hospital, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.ajpath.2012.08.009DOI Listing
November 2012

Cell-based therapies for lung vascular diseases: lessons for the future.

Proc Am Thorac Soc 2011 Nov;8(6):535-40

Ottawa Hospital Research Institute, The Ottawa Hospital, 501 Smyth Road, Ottawa, ON, K1H 8L6 Canada.

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http://dx.doi.org/10.1513/pats.201105-035MWDOI Listing
November 2011

Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis.

Am J Respir Crit Care Med 2010 Oct 17;182(8):1047-57. Epub 2010 Jun 17.

The Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada, K1H 8L6.

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http://www.atsjournals.org/doi/abs/10.1164/rccm.201001-0010O
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http://dx.doi.org/10.1164/rccm.201001-0010OCDOI Listing
October 2010

Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1.

PLoS Med 2007 Sep;4(9):e269

The Terrence Donnelly Research Laboratories, Division of Cardiology, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1371/journal.pmed.0040269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1961632PMC
September 2007

Cell-based angiopoietin-1 gene therapy for acute lung injury.

Am J Respir Crit Care Med 2007 May 22;175(10):1014-26. Epub 2007 Feb 22.

St. Michael's Hospital, Toronto, ON, M5B 1W8, Canada.

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http://dx.doi.org/10.1164/rccm.200609-1370OCDOI Listing
May 2007

Assemblage of signaling DNA enzymes with intriguing metal-ion specificities and pH dependences.

J Am Chem Soc 2003 Jun;125(25):7539-45

Department of Biochemistry, McMaster University, Health Sciences Center, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5, Canada.

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http://dx.doi.org/10.1021/ja035208+DOI Listing
June 2003

An efficient RNA-cleaving DNA enzyme that synchronizes catalysis with fluorescence signaling.

J Am Chem Soc 2003 Jan;125(2):412-20

Department of Biochemistry, McMaster University, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5 Canada.

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http://dx.doi.org/10.1021/ja0281232DOI Listing
January 2003