Publications by authors named "Shinya Sakaguchi"

27Publications

Oncostatin-M-Reactive Pericytes Aggravate Blood-Brain Barrier Dysfunction by Activating JAK/STAT3 Signaling In Vitro.

Neuroscience 2019 12 6;422:12-20. Epub 2019 Nov 6.

Department of Pharmaceutical Care and Health Sciences, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka 814-0180, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.neuroscience.2019.10.014DOI Listing
December 2019

The zinc-finger transcription factor MAZR regulates iNKT cell subset differentiation.

Cell Mol Life Sci 2019 Nov 7;76(21):4391-4404. Epub 2019 May 7.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00018-019-03119-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803753PMC
November 2019

Differential Requirement of Enhancers E8 and E8 in Cytotoxic Lineage T Cells and in Intestinal Intraepithelial Lymphocytes.

Front Immunol 2019 11;10:409. Epub 2019 Mar 11.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.3389/fimmu.2019.00409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421288PMC
July 2020

Oncostatin M-induced blood-brain barrier impairment is due to prolonged activation of STAT3 signaling in vitro.

J Cell Biochem 2018 11 4;119(11):9055-9063. Epub 2018 Aug 4.

Department of Pharmaceutical Care and Health Sciences, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.

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http://dx.doi.org/10.1002/jcb.27162DOI Listing
November 2018

The corepressor NCOR1 regulates the survival of single-positive thymocytes.

Sci Rep 2017 Nov 21;7(1):15928. Epub 2017 Nov 21.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090, Vienna, Austria.

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http://dx.doi.org/10.1038/s41598-017-15918-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698297PMC
November 2017

Acetylation of the Cd8 Locus by KAT6A Determines Memory T Cell Diversity.

Cell Rep 2016 09;16(12):3311-3321

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.08.056DOI Listing
September 2016

MAZR and Runx Factors Synergistically Repress ThPOK during CD8+ T Cell Lineage Development.

J Immunol 2015 Sep 7;195(6):2879-87. Epub 2015 Aug 7.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090 Vienna, Austria;

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http://dx.doi.org/10.4049/jimmunol.1500387DOI Listing
September 2015

PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function.

Mol Cell Biol 2015 May 9;35(10):1741-53. Epub 2015 Mar 9.

Biological Sciences and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey Sabanci University Nanotechnology Research and Application Center-SUNUM, Istanbul, Turkey

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http://dx.doi.org/10.1128/MCB.01475-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405645PMC
May 2015

A novel Cd8-cis-regulatory element preferentially directs expression in CD44hiCD62L+ CD8+ T cells and in CD8αα+ dendritic cells.

J Leukoc Biol 2015 Apr 29;97(4):635-44. Epub 2014 Dec 29.

*Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Department of Medical Biochemistry, Max F. Perutz Laboratories, Vienna Biocenter, and Institute of Vascular Biology, Medical University of Vienna, Austria; Laboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan; and CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

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http://dx.doi.org/10.1189/jlb.1HI1113-597RRDOI Listing
April 2015

Metformin induces up-regulation of blood-brain barrier functions by activating AMP-activated protein kinase in rat brain microvascular endothelial cells.

Biochem Biophys Res Commun 2013 Apr 21;433(4):586-90. Epub 2013 Mar 21.

Department of Pharmaceutical Care and Health Sciences, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2013.03.036DOI Listing
April 2013

Cd8 enhancer E8I and Runx factors regulate CD8α expression in activated CD8+ T cells.

Proc Natl Acad Sci U S A 2011 Nov 24;108(45):18330-5. Epub 2011 Oct 24.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090 Vienna, Austria.

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http://dx.doi.org/10.1073/pnas.1105835108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215065PMC
November 2011

The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes.

Nat Immunol 2010 May 11;11(5):442-8. Epub 2010 Apr 11.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1038/ni.1860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365445PMC
May 2010

Impaired T-cell development in the absence of Vav1 and Itk.

Eur J Immunol 2008 Dec;38(12):3530-42

Division of Immunobiology, Institute of Immunology, Center for Physiology, Pathophysiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/eji.200838388DOI Listing
December 2008

The transcriptional regulator PLZF induces the development of CD44 high memory phenotype T cells.

Proc Natl Acad Sci U S A 2008 Nov 12;105(46):17919-24. Epub 2008 Nov 12.

Division of Immunobiology, Institute of Immunology, Center for Physiology, Pathophysiology and Immunology, Medical University of Vienna, A-1090 Vienna, Austria.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0805733105
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http://dx.doi.org/10.1073/pnas.0805733105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584723PMC
November 2008

Regulation of luteal prostaglandin F(2 alpha) production and its relevance to cell death: an in vitro study using rat dispersed luteal cells.

Prostaglandins Other Lipid Mediat 2007 Jun 27;83(4):250-6. Epub 2006 Dec 27.

Laboratory of Physiology, Kitasato University School of Veterinary Medicine and Animal Sciences, Towada, Aomori 034-8628, Japan.

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http://dx.doi.org/10.1016/j.prostaglandins.2006.12.003DOI Listing
June 2007

Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program.

Proc Natl Acad Sci U S A 2006 Oct 3;103(41):15136-41. Epub 2006 Oct 3.

Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-0033, Japan.

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http://dx.doi.org/10.1073/pnas.0607181103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1586247PMC
October 2006

Essential role of IRF-3 in lipopolysaccharide-induced interferon-beta gene expression and endotoxin shock.

Biochem Biophys Res Commun 2003 Jul;306(4):860-6

Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-0033, Japan.

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http://dx.doi.org/10.1016/s0006-291x(03)01049-0DOI Listing
July 2003

Requirement of the IFN-alpha/beta-induced CXCR3 chemokine signalling for CD8+ T cell activation.

Genes Cells 2002 Mar;7(3):309-20

Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-0033, Japan.

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http://dx.doi.org/10.1046/j.1365-2443.2002.00515.xDOI Listing
March 2002