Publications


Beige Adipocyte Maintenance Is Regulated by Autophagy-Induced Mitochondrial Clearance.
Cell Metab 2016 Sep 25;24(3):402-19. Epub 2016 Aug 25.
UCSF Diabetes Center, San Francisco, CA 94143, USA; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, San Francisco, CA 94143, USA; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans.
Cell Metab 2016 Jun 26;23(6):1200-1206. Epub 2016 May 26.
Metabolism Unit, Shriners Hospitals for Children, Galveston, TX 77555, USA; Department of Nutrition and Metabolism, Division of Rehabilitation Sciences, University of Texas Medical Branch, Galveston, TX 77555, USA; Department of Nutrition and Dietetics, Harokopio University of Athens, Athens 176 71, Greece; Institute for Translational Sciences, University of Texas Medical Branch, Galveston, TX 77555, USA; Sealy Center on Aging, University of Texas Medical Branch, Galveston, TX 77555, USA; Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA; Department of Exercise Sciences, Rutgers University, New Brunswick, NJ 08901, USA; Department of Medicine, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ 08901, USA. Electronic address:

A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function.
Cell Metab 2016 Mar 11;23(3):454-66. Epub 2016 Feb 11.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA. Electronic address:

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Autophagy 2016 ;12(1):1-222
kb Emory University, School of Medicine , Department of Microbiology and Immunology , Atlanta , GA , USA.

Phosphoproteomics Identifies CK2 as a Negative Regulator of Beige Adipocyte Thermogenesis and Energy Expenditure.
Cell Metab 2015 Dec 8;22(6):997-1008. Epub 2015 Nov 8.
UCSF Diabetes Center and Department of Cell and Tissue Biology, University of California, San Francisco, 35 Medical Center Way, San Francisco, CA 94143-0669, USA. Electronic address:

A creatine-driven substrate cycle enhances energy expenditure and thermogenesis in beige fat.
Cell 2015 Oct 22;163(3):643-55. Epub 2015 Oct 22.
Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Cell Biology, Harvard University Medical School, Boston, MA 02115, USA. Electronic address:

JMJD1A is a signal-sensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis.
Nat Commun 2015 May 7;6:7052. Epub 2015 May 7.
1] Division of Metabolic Medicine, Research Center for Advanced Science and Technology (RCAST), The University of Tokyo, Tokyo 153-8904, Japan [2] The Translational Systems Biology and Medicine Initiative, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, University of Tokyo, Tokyo 113-8655, Japan.

Genetic and functional characterization of clonally derived adult human brown adipocytes.
Nat Med 2015 Apr 16;21(4):389-94. Epub 2015 Mar 16.
1] Diabetes Center, University of California, San Francisco (UCSF), San Francisco, California, USA. [2] Department of Cell and Tissue Biology, UCSF, San Francisco, California, USA. [3] Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, UCSF, San Francisco, California, USA.

Regulation of systemic energy homeostasis by serotonin in adipose tissues.
Nat Commun 2015 Apr 13;6:6794. Epub 2015 Apr 13.
BioMedical Research Center (E7) 8104, Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.

ThermoMouse: an in vivo model to identify modulators of UCP1 expression in brown adipose tissue.
Cell Rep 2014 Dec 26;9(5):1584-93. Epub 2014 Nov 26.
UCSF Diabetes Center, Department of Cell and Tissue Biology, University of California, San Francisco, 35 Medical Center Way, San Francisco, CA 94143, USA. Electronic address:




Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice.
J Clin Invest 2011 Jan 1;121(1):96-105. Epub 2010 Dec 1.
Institute for Diabetes, Obesity, and Metabolism and Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5.
Nature 2010 Jul;466(7305):451-6
Department of Cancer Biology and Division of Metabolism and Chronic Disease, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.

Prolactin receptor and proliferating/apoptotic cells in esophagus of the Mozambique tilapia (Oreochromis mossambicus) in fresh water and in seawater.
Gen Comp Endocrinol 2007 Jun-Jul;152(2-3):326-31. Epub 2007 Feb 28.
Ushimado Marine Laboratory, Graduate School of Natural Science and Technology, Okayama University, Ushimado, Setouchi 701-4303, Japan.

PDGFA Makes Thin Skin Thicker: Molecular Regulation of Adipose Progenitor Maintenance.
Cell Stem Cell 2016 12;19(6):675-676
UCSF Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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