Shin Yonehara

Shin Yonehara

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Shin Yonehara

Publications by authors named "Shin Yonehara"

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Molecular Mechanism of Apoptosis by Amyloid β-Protein Fibrils Formed on Neuronal Cells.

ACS Chem Neurosci 2020 Feb 14. Epub 2020 Feb 14.

Graduate School of Pharmaceutical Sciences , Kyoto University , Sakyo, Kyoto 606-8501 , Japan.

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http://dx.doi.org/10.1021/acschemneuro.0c00011DOI Listing
February 2020

Caspase-8, receptor-interacting protein kinase 1 (RIPK1), and RIPK3 regulate retinoic acid-induced cell differentiation and necroptosis.

Cell Death Differ 2019 Oct 28. Epub 2019 Oct 28.

Graduate School of Biostudies, Kyoto University, Kyoto, 606-8501, Japan.

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http://dx.doi.org/10.1038/s41418-019-0434-2DOI Listing
October 2019

Interferon-γ induces the cell surface exposure of phosphatidylserine by activating the protein MLKL in the absence of caspase-8 activity.

J Biol Chem 2019 Aug 19;294(32):11994-12006. Epub 2019 Jun 19.

Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan

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http://dx.doi.org/10.1074/jbc.RA118.007161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690710PMC
August 2019

Protein-driven RNA nanostructured devices that function in vitro and control mammalian cell fate.

Nat Commun 2017 09 14;8(1):540. Epub 2017 Sep 14.

Center for iPS Cell Research and Application, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.

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http://dx.doi.org/10.1038/s41467-017-00459-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599586PMC
September 2017

Inflammasome and Fas-Mediated IL-1β Contributes to Th17/Th1 Cell Induction in Pathogenic Bacterial Infection In Vivo.

J Immunol 2017 08 3;199(3):1122-1130. Epub 2017 Jul 3.

Department of Microbiology, Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan.

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http://dx.doi.org/10.4049/jimmunol.1601373DOI Listing
August 2017

Loss of Somatostatin Receptor Subtype 2 Promotes Growth of KRAS-Induced Pancreatic Tumors in Mice by Activating PI3K Signaling and Overexpression of CXCL16.

Gastroenterology 2015 Jun 13;148(7):1452-65. Epub 2015 Feb 13.

INSERM UMR-1037, Toulouse University, Cancer Research Center of Toulouse, Equipe Labellisée Ligue Contre le Cancer and Laboratoire d'Excellence Toulouse Cancer, Toulouse, France. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2015.02.009DOI Listing
June 2015

Pathogenic Th2-type follicular helper T cells contribute to the development of lupus in Fas-deficient mice.

Int Immunol 2014 Apr 16;26(4):221-31. Epub 2013 Dec 16.

Laboratory of Allergic Diseases, Institute for Advanced Medical Sciences, Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan.

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http://dx.doi.org/10.1093/intimm/dxt070DOI Listing
April 2014

Identification of a novel type 2 innate immunocyte with the ability to enhance IgE production.

Int Immunol 2013 Jun 14;25(6):373-82. Epub 2013 Feb 14.

Laboratory of Molecular and Cellular Biology, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1093/intimm/dxs160DOI Listing
June 2013

Fas deficiency in mice with the Balb/c background induces blepharitis with allergic inflammation and hyper-IgE production in conjunction with severe autoimmune disease.

Int Immunol 2013 May 5;25(5):287-93. Epub 2012 Dec 5.

Laboratory of Molecular and Cellular Biology, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1093/intimm/dxs109DOI Listing
May 2013

Fas-mediated inflammatory response in Listeria monocytogenes infection.

J Immunol 2013 Apr 15;190(8):4245-54. Epub 2013 Mar 15.

Department of Microbiology, Hyogo College of Medicine, Nishinomiya, 663-8501, Japan.

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http://dx.doi.org/10.4049/jimmunol.1203059DOI Listing
April 2013

Protease activity of procaspase-8 is essential for cell survival by inhibiting both apoptotic and nonapoptotic cell death dependent on receptor-interacting protein kinase 1 (RIP1) and RIP3.

J Biol Chem 2012 Nov 15;287(49):41165-73. Epub 2012 Oct 15.

Laboratory of Molecular and Cellular Biology, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1074/jbc.M112.419747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510816PMC
November 2012

Bim regulates B-cell receptor-mediated apoptosis in the presence of CD40 signaling in CD40-pre-activated splenic B cells differentiating into plasma cells.

Int Immunol 2012 May 1;24(5):283-92. Epub 2012 Feb 1.

Laboratory of Molecular and Cellular Biology, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1093/intimm/dxr127DOI Listing
May 2012

Identification of mechanism that couples multisite phosphorylation of Yes-associated protein (YAP) with transcriptional coactivation and regulation of apoptosis.

J Biol Chem 2012 Mar 3;287(12):9568-78. Epub 2012 Feb 3.

Laboratory of Molecular and Cellular Biology, Graduate School of Biostudies, Kyoto University, Sakyo-ku, Kyoto, Japan.

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http://dx.doi.org/10.1074/jbc.M111.296954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308740PMC
March 2012

SR-PSOX/CXCL16 plays a critical role in the progression of colonic inflammation.

Gut 2011 Nov 6;60(11):1494-505. Epub 2011 Apr 6.

Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1136/gut.2010.221879DOI Listing
November 2011

Identification of functional regions defining different activity in caspase-3 and caspase-7 within cells.

J Biol Chem 2010 Aug 21;285(33):25418-25. Epub 2010 Jun 21.

Laboratory of Molecular and Cellular Biology, Department of Animal Development and Physiology, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1074/jbc.M110.126573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919105PMC
August 2010

RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway.

Mol Cell 2009 Oct;36(2):193-206

Laboratory of Cell Cycle Regulation, Department of Gene Mechanisms, Graduate School of Biostudies, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1016/j.molcel.2009.08.009DOI Listing
October 2009

Interaction of FLASH with arsenite resistance protein 2 is involved in cell cycle progression at S phase.

Mol Cell Biol 2009 Sep 22;29(17):4729-41. Epub 2009 Jun 22.

Laboratory of Molecular and Cellular Biology, Graduate School of Biostudies, Kyoto University, Sakyo-ku, Kyoto, Japan.

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http://dx.doi.org/10.1128/MCB.00289-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725714PMC
September 2009

Conserved function of caspase-8 in apoptosis during bony fish evolution.

Gene 2007 Jul 27;396(1):134-48. Epub 2007 Mar 27.

Department of Animal Development and Physiology, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1016/j.gene.2007.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064871PMC
July 2007

Scavenger receptors for oxidized lipoprotein in age-related macular degeneration.

Invest Ophthalmol Vis Sci 2007 Apr;48(4):1801-7

Department of Ophthalmology, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1167/iovs.06-0699DOI Listing
April 2007

Rapid up-regulation of c-FLIP expression by BCR signaling through the PI3K/Akt pathway inhibits simultaneously induced Fas-mediated apoptosis in murine B lymphocytes.

Immunol Lett 2007 Mar 22;109(1):36-46. Epub 2007 Jan 22.

Graduate School of Biostudies, Kyoto University, SCRB/Building G, Yoshida Konoecho, Sakyo-ku, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1016/j.imlet.2006.12.009DOI Listing
March 2007

Intervention of MAdCAM-1 or fractalkine alleviates graft-versus-host reaction associated intestinal injury while preserving graft-versus-tumor effects.

J Leukoc Biol 2007 Jan 19;81(1):176-85. Epub 2006 Oct 19.

Department of Molecular Preventive Medicine, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

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http://dx.doi.org/10.1189/jlb.0306231DOI Listing
January 2007

Continuous ERK activation downregulates antiproliferative genes throughout G1 phase to allow cell-cycle progression.

Curr Biol 2006 Jun;16(12):1171-82

Department of Cell and Developmental Biology, Graduate School of Biostudies, Kyoto University, Kyoto 606-8502, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S096098220601561
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http://dx.doi.org/10.1016/j.cub.2006.04.044DOI Listing
June 2006

Roles of caspase-8 and caspase-10 in innate immune responses to double-stranded RNA.

J Immunol 2006 Apr;176(8):4520-4

Department of Host Defense, Japan Science and Technology Agency, Research Institute for Microbial Diseases, Osaka University, Suita.

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http://dx.doi.org/10.4049/jimmunol.176.8.4520DOI Listing
April 2006

Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis.

Cancer Res 2006 Mar;66(5):2562-9

Department of Biological Sciences, Biomedical Research Center, Korea Advanced Institute of Science and Technology, Daejeon, South Korea.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-05-2951DOI Listing
March 2006

Viral FLIP enhances Wnt signaling downstream of stabilized beta-catenin, leading to control of cell growth.

Mol Cell Biol 2005 Nov;25(21):9249-58

Graduate School of Biostudies, Kyoto University, SCRB/Building G, Yoshida Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.25.21.9249-9258.2005
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http://dx.doi.org/10.1128/MCB.25.21.9249-9258.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1265812PMC
November 2005

Pathogenic role of the CXCL16-CXCR6 pathway in rheumatoid arthritis.

Arthritis Rheum 2005 Oct;52(10):3004-14

Department of Medicine and Rheumatology, Graduate School, Tokyo Medical and Dental University, Yushima, Tokyo, Japan.

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http://doi.wiley.com/10.1002/art.21301
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http://dx.doi.org/10.1002/art.21301DOI Listing
October 2005

Partial correction of abnormal cardiac development in caspase-8-deficient mice by cardiomyocyte expression of p 35.

Transgenic Res 2005 Oct;14(5):593-604

Department of Animal Development and Physiology, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1007/s11248-005-4350-5DOI Listing
October 2005

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity.

J Immunol 2005 Sep;175(5):2851-8

Antiviral Innate Immunity Project, Tokyo Metropolitan Institute of Medical Science, Tokyo Metropolitan Organization for Medical Research, Honkomagome, Tokyo, Japan.

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http://dx.doi.org/10.4049/jimmunol.175.5.2851DOI Listing
September 2005

The tumor suppressor WARTS activates the Omi / HtrA2-dependent pathway of cell death.

Oncogene 2005 Aug;24(34):5287-98

Department of Tumor Genetics and Biology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto 860-8556, Japan.

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http://dx.doi.org/10.1038/sj.onc.1208682DOI Listing
August 2005

Acquisition of Fas resistance by Fas receptor mutation in a childhood B-precursor acute lymphoblastic leukemia cell line, MML-1.

Int J Oncol 2005 Aug;27(2):573-9

Department of Pediatrics, Mie University School of Medicine, Tsu, Mie 514-8507, Japan.

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August 2005

Cutting edge: critical role of CXCL16/CXCR6 in NKT cell trafficking in allograft tolerance.

J Immunol 2005 Aug;175(4):2051-5

Laboratory for Immune Regulation, RIKEN Research Center for Allergy and Immunology, Kanagawa, Japan.

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http://dx.doi.org/10.4049/jimmunol.175.4.2051DOI Listing
August 2005

CXCL16 is a novel angiogenic factor for human umbilical vein endothelial cells.

Biochem Biophys Res Commun 2005 Jun;331(4):1295-300

Department of Clinical Innovative Medicine, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0500679
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http://dx.doi.org/10.1016/j.bbrc.2005.03.200DOI Listing
June 2005

Distribution and kinetics of SR-PSOX/CXCL16 and CXCR6 expression on human dendritic cell subsets and CD4+ T cells.

J Leukoc Biol 2005 May 9;77(5):777-86. Epub 2005 Feb 9.

Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan.

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http://doi.wiley.com/10.1189/jlb.1204733
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http://dx.doi.org/10.1189/jlb.1204733DOI Listing
May 2005

[TNF family (TNF alpha, beta, FasL, CD40L)].

Nihon Rinsho 2005 Apr;63 Suppl 4:202-6

Laboratory of Molecular and Cellular Biology, Graduate School of Biostudies, Kyoto University.

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April 2005

The adaptor molecule FADD from Xenopus laevis demonstrates evolutionary conservation of its pro-apoptotic activity.

Genes Cells 2004 Dec;9(12):1249-64

Department of Animal Development and Physiology, Graduate School of Biostudies, Kyoto University, Kyoto 606-8507, Japan.

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http://doi.wiley.com/10.1111/j.1365-2443.2004.00802.x
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http://dx.doi.org/10.1111/j.1365-2443.2004.00802.xDOI Listing
December 2004

hDKIR, a human homologue of the Drosophila kelch protein, involved in a ring-like structure.

Exp Cell Res 2004 Oct;300(1):72-83

M, F, L Science Center, Tensei-suisan Co., Saga 847-0193, Japan.

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http://dx.doi.org/10.1016/j.yexcr.2004.06.023DOI Listing
October 2004

A caspase-8-independent signaling pathway activated by Fas ligation leads to exposure of the Bak N terminus.

J Biol Chem 2004 Aug 24;279(32):33865-74. Epub 2004 May 24.

Laboratory of Molecular Genetics, Department of Post-Genomics and Diseases, Osaka University Medical School and Solution-Oriented Research for Science and Technology, Japan Science and Technology Corp., 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M403499200
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http://dx.doi.org/10.1074/jbc.M403499200DOI Listing
August 2004

Age-related thymic involution is mediated by Fas on thymic epithelial cells.

Int Immunol 2004 Jul 10;16(7):1027-35. Epub 2004 Jun 10.

Graduate School of Biostudies and Institute for Virus Research, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1093/intimm/dxh104DOI Listing
July 2004

The role of Fas-mediated apoptosis after traumatic spinal cord injury.

Spine (Phila Pa 1976) 2004 Jul;29(13):1394-404

Department of Orthopaedic Surgery, Toyama Medical and Pharmaceutical University, Toyama, Japan.

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http://pdfs.journals.lww.com/spinejournal/2004/07010/The_Rol
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http://dx.doi.org/10.1097/01.brs.0000129894.34550.48DOI Listing
July 2004

Chemokines generally exhibit scavenger receptor activity through their receptor-binding domain.

J Biol Chem 2004 Jun 5;279(26):26807-10. Epub 2004 May 5.

Graduate School of Biostudies and Institute for Virus Research, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1074/jbc.C400163200DOI Listing
June 2004

Cutting edge: SR-PSOX/CXC chemokine ligand 16 mediates bacterial phagocytosis by APCs through its chemokine domain.

J Immunol 2003 Aug;171(4):1647-51

Graduate School of Biostudies and Institute for Virus Research, Kyoto University, Sakyo-ku, Kyoto, Japan.

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http://dx.doi.org/10.4049/jimmunol.171.4.1647DOI Listing
August 2003

c-Jun NH2-terminal kinase-dependent Fas activation contributes to etoposide-induced apoptosis in p53-mutated prostate cancer cells.

Prostate 2003 Jun;55(4):265-80

Second Department of Pathology, Nara Medical University, Kashihara, Nara, Japan.

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http://dx.doi.org/10.1002/pros.10227DOI Listing
June 2003

Death receptor Fas and autoimmune disease: from the original generation to therapeutic application of agonistic anti-Fas monoclonal antibody.

Authors:
Shin Yonehara

Cytokine Growth Factor Rev 2002 Aug-Oct;13(4-5):393-402

Graduate School of Biostudies and Institute for Virus Research, Kyoto University, Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1016/s1359-6101(02)00024-2DOI Listing
March 2003

To reviews on physiological and pathological roles of cell death.

Authors:
Shin Yonehara

Cell Struct Funct 2003 Feb;28(1):1-2

Graduate School of Biostudies and Institute for Virus Research, Kyoto University, Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1247/csf.28.1DOI Listing
February 2003

Translocation of analogues of the antimicrobial peptides magainin and buforin across human cell membranes.

J Biol Chem 2003 Jan 1;278(2):1310-5. Epub 2002 Nov 1.

Graduate School of Biostudies, Kyoto University, Sakyo-ku, Japan.

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http://dx.doi.org/10.1074/jbc.M208762200DOI Listing
January 2003

[Molecular regulatory mechanism of Fas-mediated apoptosis].

Authors:
Shin Yonehara

Tanpakushitsu Kakusan Koso 2002 Dec;47(16 Suppl):2268-73

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December 2002

Phosphorylation of Fas-associated death domain contributes to enhancement of etoposide-induced apoptosis in prostate cancer cells.

Jpn J Cancer Res 2002 Oct;93(10):1164-74

Second Department of Pathology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8521, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926882PMC
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01219.xDOI Listing
October 2002

Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation.

Hum Mol Genet 2002 Jun;11(13):1505-15

Division of Development and Differentiation, National Institute of Neuroscience, 4-1-1 Ogawahigashi-machi, Kodaira, Tokyo 187-8502, Japan.

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http://dx.doi.org/10.1093/hmg/11.13.1505DOI Listing
June 2002

Phosphorylation and dimerization regulate nucleocytoplasmic shuttling of mammalian STE20-like kinase (MST).

J Biol Chem 2002 Apr 22;277(14):12351-8. Epub 2002 Jan 22.

Institute for Virus Research and Graduate School of Biostudies, Kyoto University, Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1074/jbc.M108138200DOI Listing
April 2002