Publications by authors named "Shimon Sakaguchi"

100Publications

PTPN2 links colonic and joint inflammation in experimental autoimmune arthritis.

JCI Insight 2020 Oct 15;5(20). Epub 2020 Oct 15.

Department of Medicine, UCSD School of Medicine, La Jolla, California, USA.

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http://dx.doi.org/10.1172/jci.insight.141868DOI Listing
October 2020

VIRTUS: a pipeline for comprehensive virus analysis from conventional RNA-seq data.

Bioinformatics 2020 Oct 5. Epub 2020 Oct 5.

Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1093/bioinformatics/btaa859DOI Listing
October 2020

New Treg cell-based therapies of autoimmune diseases: towards antigen-specific immune suppression.

Curr Opin Immunol 2020 Aug 19;67:36-41. Epub 2020 Aug 19.

Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Yamadaoka, Suita, Osaka 565-0871, Japan; Laboratory of Experimental Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2020.07.004DOI Listing
August 2020

Control of foreign Ag-specific Ab responses by Treg and Tfr.

Immunol Rev 2020 Jul 20;296(1):104-119. Epub 2020 Jun 20.

Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Suita, Japan.

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http://dx.doi.org/10.1111/imr.12888DOI Listing
July 2020

Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation.

Proc Natl Acad Sci U S A 2020 06 15;117(22):12258-12268. Epub 2020 May 15.

Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Yamadaoka, 565-0871 Suita, Osaka, Japan;

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http://dx.doi.org/10.1073/pnas.1922600117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275710PMC
June 2020

Transcriptional and epigenetic basis of Treg cell development and function: its genetic anomalies or variations in autoimmune diseases.

Cell Res 2020 Jun 4;30(6):465-474. Epub 2020 May 4.

Experimental immunology, Immunology Frontier Research Center, Osaka University, 3-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.

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http://dx.doi.org/10.1038/s41422-020-0324-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264322PMC
June 2020

Regulatory T Cell-Specific Epigenomic Region Variants Are a Key Determinant of Susceptibility to Common Autoimmune Diseases.

Immunity 2020 Jun 1;52(6):1119-1132.e4. Epub 2020 May 1.

Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.04.006DOI Listing
June 2020

Dynamics of effector and naïve Regulatory T cells throughout pregnancy.

J Reprod Immunol 2020 Aug 19;140:103135. Epub 2020 Apr 19.

Department of obstetrics and gynecology, Osaka university, 1-1 Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/j.jri.2020.103135DOI Listing
August 2020

Regulatory T Cells and Human Disease.

Annu Rev Immunol 2020 Apr 4;38:541-566. Epub 2020 Feb 4.

Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Yamadaoka, Suita, Osaka 565-0871, Japan; email:

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http://dx.doi.org/10.1146/annurev-immunol-042718-041717DOI Listing
April 2020

Impaired T cell receptor signaling and development of T cell-mediated autoimmune arthritis.

Immunol Rev 2020 03 16;294(1):164-176. Epub 2020 Jan 16.

Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1111/imr.12841DOI Listing
March 2020

Control of Regulatory T Cells by Co-signal Molecules.

Adv Exp Med Biol 2019 ;1189:179-210

Laboratory of Experimental Immunology, WPI Immunology Frontier Research Center (IFReC), Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1007/978-981-32-9717-3_7DOI Listing
December 2019

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).

Authors:
Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Andreas Acs Dieter Adam Sabine Adam-Klages William W Agace Nima Aghaeepour Mübeccel Akdis Matthieu Allez Larissa Nogueira Almeida Giorgia Alvisi Graham Anderson Immanuel Andrä Francesco Annunziato Achille Anselmo Petra Bacher Cosima T Baldari Sudipto Bari Vincenzo Barnaba Joana Barros-Martins Luca Battistini Wolfgang Bauer Sabine Baumgart Nicole Baumgarth Dirk Baumjohann Bianka Baying Mary Bebawy Burkhard Becher Wolfgang Beisker Vladimir Benes Rudi Beyaert Alfonso Blanco Dominic A Boardman Christian Bogdan Jessica G Borger Giovanna Borsellino Philip E Boulais Jolene A Bradford Dirk Brenner Ryan R Brinkman Anna E S Brooks Dirk H Busch Martin Büscher Timothy P Bushnell Federica Calzetti Garth Cameron Ilenia Cammarata Xuetao Cao Susanna L Cardell Stefano Casola Marco A Cassatella Andrea Cavani Antonio Celada Lucienne Chatenoud Pratip K Chattopadhyay Sue Chow Eleni Christakou Luka Čičin-Šain Mario Clerici Federico S Colombo Laura Cook Anne Cooke Andrea M Cooper Alexandra J Corbett Antonio Cosma Lorenzo Cosmi Pierre G Coulie Ana Cumano Ljiljana Cvetkovic Van Duc Dang Chantip Dang-Heine Martin S Davey Derek Davies Sara De Biasi Genny Del Zotto Gelo Victoriano Dela Cruz Michael Delacher Silvia Della Bella Paolo Dellabona Günnur Deniz Mark Dessing James P Di Santo Andreas Diefenbach Francesco Dieli Andreas Dolf Thomas Dörner Regine J Dress Diana Dudziak Michael Dustin Charles-Antoine Dutertre Friederike Ebner Sidonia B G Eckle Matthias Edinger Pascale Eede Götz R A Ehrhardt Marcus Eich Pablo Engel Britta Engelhardt Anna Erdei Charlotte Esser Bart Everts Maximilien Evrard Christine S Falk Todd A Fehniger Mar Felipo-Benavent Helen Ferry Markus Feuerer Andrew Filby Kata Filkor Simon Fillatreau Marie Follo Irmgard Förster John Foster Gemma A Foulds Britta Frehse Paul S Frenette Stefan Frischbutter Wolfgang Fritzsche David W Galbraith Anastasia Gangaev Natalio Garbi Brice Gaudilliere Ricardo T Gazzinelli Jens Geginat Wilhelm Gerner Nicholas A Gherardin Kamran Ghoreschi Lara Gibellini Florent Ginhoux Keisuke Goda Dale I Godfrey Christoph Goettlinger Jose M González-Navajas Carl S Goodyear Andrea Gori Jane L Grogan Daryl Grummitt Andreas Grützkau Claudia Haftmann Jonas Hahn Hamida Hammad Günter Hämmerling Leo Hansmann Goran Hansson Christopher M Harpur Susanne Hartmann Andrea Hauser Anja E Hauser David L Haviland David Hedley Daniela C Hernández Guadalupe Herrera Martin Herrmann Christoph Hess Thomas Höfer Petra Hoffmann Kristin Hogquist Tristan Holland Thomas Höllt Rikard Holmdahl Pleun Hombrink Jessica P Houston Bimba F Hoyer Bo Huang Fang-Ping Huang Johanna E Huber Jochen Huehn Michael Hundemer Christopher A Hunter William Y K Hwang Anna Iannone Florian Ingelfinger Sabine M Ivison Hans-Martin Jäck Peter K Jani Beatriz Jávega Stipan Jonjic Toralf Kaiser Tomas Kalina Thomas Kamradt Stefan H E Kaufmann Baerbel Keller Steven L C Ketelaars Ahad Khalilnezhad Srijit Khan Jan Kisielow Paul Klenerman Jasmin Knopf Hui-Fern Koay Katja Kobow Jay K Kolls Wan Ting Kong Manfred Kopf Thomas Korn Katharina Kriegsmann Hendy Kristyanto Thomas Kroneis Andreas Krueger Jenny Kühne Christian Kukat Désirée Kunkel Heike Kunze-Schumacher Tomohiro Kurosaki Christian Kurts Pia Kvistborg Immanuel Kwok Jonathan Landry Olivier Lantz Paola Lanuti Francesca LaRosa Agnès Lehuen Salomé LeibundGut-Landmann Michael D Leipold Leslie Y T Leung Megan K Levings Andreia C Lino Francesco Liotta Virginia Litwin Yanling Liu Hans-Gustaf Ljunggren Michael Lohoff Giovanna Lombardi Lilly Lopez Miguel López-Botet Amy E Lovett-Racke Erik Lubberts Herve Luche Burkhard Ludewig Enrico Lugli Sebastian Lunemann Holden T Maecker Laura Maggi Orla Maguire Florian Mair Kerstin H Mair Alberto Mantovani Rudolf A Manz Aaron J Marshall Alicia Martínez-Romero Glòria Martrus Ivana Marventano Wlodzimierz Maslinski Giuseppe Matarese Anna Vittoria Mattioli Christian Maueröder Alessio Mazzoni James McCluskey Mairi McGrath Helen M McGuire Iain B McInnes Henrik E Mei Fritz Melchers Susanne Melzer Dirk Mielenz Stephen D Miller Kingston H G Mills Hans Minderman Jenny Mjösberg Jonni Moore Barry Moran Lorenzo Moretta Tim R Mosmann Susann Müller Gabriele Multhoff Luis Enrique Muñoz Christian Münz Toshinori Nakayama Milena Nasi Katrin Neumann Lai Guan Ng Antonia Niedobitek Sussan Nourshargh Gabriel Núñez José-Enrique O'Connor Aaron Ochel Anna Oja Diana Ordonez Alberto Orfao Eva Orlowski-Oliver Wenjun Ouyang Annette Oxenius Raghavendra Palankar Isabel Panse Kovit Pattanapanyasat Malte Paulsen Dinko Pavlinic Livius Penter Pärt Peterson Christian Peth Jordi Petriz Federica Piancone Winfried F Pickl Silvia Piconese Marcello Pinti A Graham Pockley Malgorzata Justyna Podolska Zhiyong Poon Katharina Pracht Immo Prinz Carlo E M Pucillo Sally A Quataert Linda Quatrini Kylie M Quinn Helena Radbruch Tim R D J Radstake Susann Rahmig Hans-Peter Rahn Bartek Rajwa Gevitha Ravichandran Yotam Raz Jonathan A Rebhahn Diether Recktenwald Dorothea Reimer Caetano Reis e Sousa Ester B M Remmerswaal Lisa Richter Laura G Rico Andy Riddell Aja M Rieger J Paul Robinson Chiara Romagnani Anna Rubartelli Jürgen Ruland Armin Saalmüller Yvan Saeys Takashi Saito Shimon Sakaguchi Francisco Sala-de-Oyanguren Yvonne Samstag Sharon Sanderson Inga Sandrock Angela Santoni Ramon Bellmàs Sanz Marina Saresella Catherine Sautes-Fridman Birgit Sawitzki Linda Schadt Alexander Scheffold Hans U Scherer Matthias Schiemann Frank A Schildberg Esther Schimisky Andreas Schlitzer Josephine Schlosser Stephan Schmid Steffen Schmitt Kilian Schober Daniel Schraivogel Wolfgang Schuh Thomas Schüler Reiner Schulte Axel Ronald Schulz Sebastian R Schulz Cristiano Scottá Daniel Scott-Algara David P Sester T Vincent Shankey Bruno Silva-Santos Anna Katharina Simon Katarzyna M Sitnik Silvano Sozzani Daniel E Speiser Josef Spidlen Anders Stahlberg Alan M Stall Natalie Stanley Regina Stark Christina Stehle Tobit Steinmetz Hannes Stockinger Yousuke Takahama Kiyoshi Takeda Leonard Tan Attila Tárnok Gisa Tiegs Gergely Toldi Julia Tornack Elisabetta Traggiai Mohamed Trebak Timothy I M Tree Joe Trotter John Trowsdale Maria Tsoumakidou Henning Ulrich Sophia Urbanczyk Willem van de Veen Maries van den Broek Edwin van der Pol Sofie Van Gassen Gert Van Isterdael René A W van Lier Marc Veldhoen Salvador Vento-Asturias Paulo Vieira David Voehringer Hans-Dieter Volk Anouk von Borstel Konrad von Volkmann Ari Waisman Rachael V Walker Paul K Wallace Sa A Wang Xin M Wang Michael D Ward Kirsten A Ward-Hartstonge Klaus Warnatz Gary Warnes Sarah Warth Claudia Waskow James V Watson Carsten Watzl Leonie Wegener Thomas Weisenburger Annika Wiedemann Jürgen Wienands Anneke Wilharm Robert John Wilkinson Gerald Willimsky James B Wing Rieke Winkelmann Thomas H Winkler Oliver F Wirz Alicia Wong Peter Wurst Jennie H M Yang Juhao Yang Maria Yazdanbakhsh Liping Yu Alice Yue Hanlin Zhang Yi Zhao Susanne Maria Ziegler Christina Zielinski Jakob Zimmermann Arturo Zychlinsky

Eur J Immunol 2019 Oct;49(10):1457-1973

Max Planck Institute for Infection Biology, Berlin, Germany.

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http://dx.doi.org/10.1002/eji.201970107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350392PMC
October 2019

Synovial Tissue Inflammation Mediated by Autoimmune T Cells.

Front Immunol 2019 21;10:1989. Epub 2019 Aug 21.

Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.3389/fimmu.2019.01989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712680PMC
October 2020

Targeting Treg cells in cancer immunotherapy.

Eur J Immunol 2019 08 5;49(8):1140-1146. Epub 2019 Jul 5.

Laboratory of Experimental Immunology, WPI Immunology Frontier Research Center, Osaka University, Suita, Japan.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/eji.20184765
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http://dx.doi.org/10.1002/eji.201847659DOI Listing
August 2019

Regulatory roles of IL-10-producing human follicular T cells.

J Exp Med 2019 08 17;216(8):1843-1856. Epub 2019 Jun 17.

Department of Immunology and Infectious Disease and Centre for Personalised Immunology, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia

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http://dx.doi.org/10.1084/jem.20190493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683995PMC
August 2019

PD-1 regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer.

Proc Natl Acad Sci U S A 2019 05 26;116(20):9999-10008. Epub 2019 Apr 26.

Division of Cancer Immunology, Research Institute/Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 104-0045 Tokyo, Japan;

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http://dx.doi.org/10.1073/pnas.1822001116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525547PMC
May 2019

Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction.

Immunity 2019 05 23;50(5):1232-1248.e14. Epub 2019 Apr 23.

Molecular Immunology in Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Str. 27, 53127 Bonn, Germany; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany; PRECISE, Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Sigmund-Freud-Str. 27, 53127 Bonn, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613193013
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http://dx.doi.org/10.1016/j.immuni.2019.03.014DOI Listing
May 2019

Human FOXP3 Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer.

Immunity 2019 02;50(2):302-316

Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Suita 565-0871, Japan; Department of Experimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.01.020DOI Listing
February 2019

Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation.

Nat Commun 2019 02 1;10(1):549. Epub 2019 Feb 1.

Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan.

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http://www.nature.com/articles/s41467-019-08404-w
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http://dx.doi.org/10.1038/s41467-019-08404-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358604PMC
February 2019

Regulatory T cells expressing abundant CTLA-4 on the cell surface with a proliferative gene profile are key features of human head and neck cancer.

Int J Cancer 2019 06 16;144(11):2811-2822. Epub 2018 Dec 16.

Department of Immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

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http://dx.doi.org/10.1002/ijc.32024DOI Listing
June 2019

Are naïve T cells and class-switched memory (IgD CD27) B cells not essential for establishment and maintenance of pregnancy? Insights from a case of common variable immunodeficiency with pregnancy.

Med Hypotheses 2018 Dec 8;121:36-41. Epub 2018 Sep 8.

Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 5650871, Japan.

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http://dx.doi.org/10.1016/j.mehy.2018.09.014DOI Listing
December 2018

Preparation of Immunotolerant Space Under the Skin and Transplantation of Islets in the Space.

Tissue Eng Part A 2019 02 28;25(3-4):183-192. Epub 2018 Dec 28.

5 RIKEN, Compass to Healthy Research Complex Program, Hyogo, Japan.

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http://dx.doi.org/10.1089/ten.TEA.2018.0109DOI Listing
February 2019

Control of Germinal Center Responses by T-Follicular Regulatory Cells.

Front Immunol 2018 24;9:1910. Epub 2018 Aug 24.

Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Suita, Japan.

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http://dx.doi.org/10.3389/fimmu.2018.01910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117393PMC
September 2019

Regulatory T-cell deficiency and autoimmune skin disease: Beyond the scurfy mouse and immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome.

J Allergy Clin Immunol 2018 12 6;142(6):1754-1756. Epub 2018 Sep 6.

Experimental Immunology, Osaka University Immunology Frontier Research Center, Osaka, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183127
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http://dx.doi.org/10.1016/j.jaci.2018.08.028DOI Listing
December 2018

Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.

Immunity 2018 06 22;48(6):1220-1232.e5. Epub 2018 May 22.

Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan; Laboratory of Experimental Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024031PMC
June 2018

Ultraviolet B-Induced Maturation of CD11b-Type Langerin Dendritic Cells Controls the Expansion of Foxp3 Regulatory T Cells in the Skin.

J Immunol 2018 01 20;200(1):119-129. Epub 2017 Nov 20.

Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.

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http://dx.doi.org/10.4049/jimmunol.1701056DOI Listing
January 2018

Slc3a2 Mediates Branched-Chain Amino-Acid-Dependent Maintenance of Regulatory T Cells.

Cell Rep 2017 Nov;21(7):1824-1838

Laboratory of Immune Regulation, Department of Microbiology and Immunology, Graduate School of Medicine, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan; Core Research for Evolutional Science and Technology, Japan Agency for Medical Research and Development, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.10.082DOI Listing
November 2017

Molecular control of regulatory T cell development and function.

Curr Opin Immunol 2017 Dec 21;49:64-70. Epub 2017 Oct 21.

Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita 565-0871, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2017.10.002DOI Listing
December 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

Authors:
Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Mübeccel Akdis Immanuel Andrä Francesco Annunziato Petra Bacher Vincenzo Barnaba Luca Battistini Wolfgang M Bauer Sabine Baumgart Burkhard Becher Wolfgang Beisker Claudia Berek Alfonso Blanco Giovanna Borsellino Philip E Boulais Ryan R Brinkman Martin Büscher Dirk H Busch Timothy P Bushnell Xuetao Cao Andrea Cavani Pratip K Chattopadhyay Qingyu Cheng Sue Chow Mario Clerici Anne Cooke Antonio Cosma Lorenzo Cosmi Ana Cumano Van Duc Dang Derek Davies Sara De Biasi Genny Del Zotto Silvia Della Bella Paolo Dellabona Günnur Deniz Mark Dessing Andreas Diefenbach James Di Santo Francesco Dieli Andreas Dolf Vera S Donnenberg Thomas Dörner Götz R A Ehrhardt Elmar Endl Pablo Engel Britta Engelhardt Charlotte Esser Bart Everts Anita Dreher Christine S Falk Todd A Fehniger Andrew Filby Simon Fillatreau Marie Follo Irmgard Förster John Foster Gemma A Foulds Paul S Frenette David Galbraith Natalio Garbi Maria Dolores García-Godoy Jens Geginat Kamran Ghoreschi Lara Gibellini Christoph Goettlinger Carl S Goodyear Andrea Gori Jane Grogan Mor Gross Andreas Grützkau Daryl Grummitt Jonas Hahn Quirin Hammer Anja E Hauser David L Haviland David Hedley Guadalupe Herrera Martin Herrmann Falk Hiepe Tristan Holland Pleun Hombrink Jessica P Houston Bimba F Hoyer Bo Huang Christopher A Hunter Anna Iannone Hans-Martin Jäck Beatriz Jávega Stipan Jonjic Kerstin Juelke Steffen Jung Toralf Kaiser Tomas Kalina Baerbel Keller Srijit Khan Deborah Kienhöfer Thomas Kroneis Désirée Kunkel Christian Kurts Pia Kvistborg Joanne Lannigan Olivier Lantz Anis Larbi Salome LeibundGut-Landmann Michael D Leipold Megan K Levings Virginia Litwin Yanling Liu Michael Lohoff Giovanna Lombardi Lilly Lopez Amy Lovett-Racke Erik Lubberts Burkhard Ludewig Enrico Lugli Holden T Maecker Glòria Martrus Giuseppe Matarese Christian Maueröder Mairi McGrath Iain McInnes Henrik E Mei Fritz Melchers Susanne Melzer Dirk Mielenz Kingston Mills David Mirrer Jenny Mjösberg Jonni Moore Barry Moran Alessandro Moretta Lorenzo Moretta Tim R Mosmann Susann Müller Werner Müller Christian Münz Gabriele Multhoff Luis Enrique Munoz Kenneth M Murphy Toshinori Nakayama Milena Nasi Christine Neudörfl John Nolan Sussan Nourshargh José-Enrique O'Connor Wenjun Ouyang Annette Oxenius Raghav Palankar Isabel Panse Pärt Peterson Christian Peth Jordi Petriz Daisy Philips Winfried Pickl Silvia Piconese Marcello Pinti A Graham Pockley Malgorzata Justyna Podolska Carlo Pucillo Sally A Quataert Timothy R D J Radstake Bartek Rajwa Jonathan A Rebhahn Diether Recktenwald Ester B M Remmerswaal Katy Rezvani Laura G Rico J Paul Robinson Chiara Romagnani Anna Rubartelli Beate Ruckert Jürgen Ruland Shimon Sakaguchi Francisco Sala-de-Oyanguren Yvonne Samstag Sharon Sanderson Birgit Sawitzki Alexander Scheffold Matthias Schiemann Frank Schildberg Esther Schimisky Stephan A Schmid Steffen Schmitt Kilian Schober Thomas Schüler Axel Ronald Schulz Ton Schumacher Cristiano Scotta T Vincent Shankey Anat Shemer Anna-Katharina Simon Josef Spidlen Alan M Stall Regina Stark Christina Stehle Merle Stein Tobit Steinmetz Hannes Stockinger Yousuke Takahama Attila Tarnok ZhiGang Tian Gergely Toldi Julia Tornack Elisabetta Traggiai Joe Trotter Henning Ulrich Marlous van der Braber René A W van Lier Marc Veldhoen Salvador Vento-Asturias Paulo Vieira David Voehringer Hans-Dieter Volk Konrad von Volkmann Ari Waisman Rachael Walker Michael D Ward Klaus Warnatz Sarah Warth James V Watson Carsten Watzl Leonie Wegener Annika Wiedemann Jürgen Wienands Gerald Willimsky James Wing Peter Wurst Liping Yu Alice Yue Qianjun Zhang Yi Zhao Susanne Ziegler Jakob Zimmermann

Eur J Immunol 2017 10;47(10):1584-1797

Maurice Müller Laboratories (DKF), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, University of Bern, Murtenstrasse, Bern.

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http://doi.wiley.com/10.1002/eji.201646632
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http://dx.doi.org/10.1002/eji.201646632DOI Listing
October 2017

FANTOM5 CAGE profiles of human and mouse samples.

Authors:
Shuhei Noguchi Takahiro Arakawa Shiro Fukuda Masaaki Furuno Akira Hasegawa Fumi Hori Sachi Ishikawa-Kato Kaoru Kaida Ai Kaiho Mutsumi Kanamori-Katayama Tsugumi Kawashima Miki Kojima Atsutaka Kubosaki Ri-Ichiroh Manabe Mitsuyoshi Murata Sayaka Nagao-Sato Kenichi Nakazato Noriko Ninomiya Hiromi Nishiyori-Sueki Shohei Noma Eri Saijyo Akiko Saka Mizuho Sakai Christophe Simon Naoko Suzuki Michihira Tagami Shoko Watanabe Shigehiro Yoshida Peter Arner Richard A Axton Magda Babina J Kenneth Baillie Timothy C Barnett Anthony G Beckhouse Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher Ailsa J Carlisle Hans C Clevers Carrie A Davis Michael Detmar Taeko Dohi Albert S B Edge Matthias Edinger Anna Ehrlund Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Afsaneh Eslami Michela Fagiolini Lynsey Fairbairn Mary C Farach-Carson Geoffrey J Faulkner Carmelo Ferrai Malcolm E Fisher Lesley M Forrester Rie Fujita Jun-Ichi Furusawa Teunis B Geijtenbeek Thomas Gingeras Daniel Goldowitz Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Yuki Hasegawa Meenhard Herlyn Peter Heutink Kelly J Hitchens David A Hume Tomokatsu Ikawa Yuri Ishizu Chieko Kai Hiroshi Kawamoto Yuki I Kawamura Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura Sarah Klein S Peter Klinken Alan J Knox Soichi Kojima Haruhiko Koseki Shigeo Koyasu Weonju Lee Andreas Lennartsson Alan Mackay-Sim Niklas Mejhert Yosuke Mizuno Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Kelly J Morris Hozumi Motohashi Christine L Mummery Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Tadasuke Nozaki Soichi Ogishima Naganari Ohkura Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Robert Passier Margaret Patrikakis Ana Pombo Swati Pradhan-Bhatt Xian-Yang Qin Michael Rehli Patrizia Rizzu Sugata Roy Antti Sajantila Shimon Sakaguchi Hiroki Sato Hironori Satoh Suzana Savvi Alka Saxena Christian Schmidl Claudio Schneider Gundula G Schulze-Tanzil Anita Schwegmann Guojun Sheng Jay W Shin Daisuke Sugiyama Takaaki Sugiyama Kim M Summers Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Andru Tomoiu Hiroo Toyoda Marc van de Wetering Linda M van den Berg Roberto Verardo Dipti Vijayan Christine A Wells Louise N Winteringham Ernst Wolvetang Yoko Yamaguchi Masayuki Yamamoto Chiyo Yanagi-Mizuochi Misako Yoneda Yohei Yonekura Peter G Zhang Silvia Zucchelli Imad Abugessaisa Erik Arner Jayson Harshbarger Atsushi Kondo Timo Lassmann Marina Lizio Serkan Sahin Thierry Sengstag Jessica Severin Hisashi Shimoji Masanori Suzuki Harukazu Suzuki Jun Kawai Naoto Kondo Masayoshi Itoh Carsten O Daub Takeya Kasukawa Hideya Kawaji Piero Carninci Alistair R R Forrest Yoshihide Hayashizaki

Sci Data 2017 08 29;4:170112. Epub 2017 Aug 29.

RIKEN Omics Science Center, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1038/sdata.2017.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574368PMC
August 2017

A distinct subpopulation of CD25 T-follicular regulatory cells localizes in the germinal centers.

Proc Natl Acad Sci U S A 2017 08 11;114(31):E6400-E6409. Epub 2017 Jul 11.

Laboratory of Experimental Immunology, WPI Immunology Frontier Research Center (IFReC), Osaka University, Suita 565-0871, Japan;

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http://dx.doi.org/10.1073/pnas.1705551114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547636PMC
August 2017

Systemic Activation of NRF2 Alleviates Lethal Autoimmune Inflammation in Scurfy Mice.

Mol Cell Biol 2017 08 14;37(15). Epub 2017 Jul 14.

Department of Gene Expression Regulation, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan

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http://dx.doi.org/10.1128/MCB.00063-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514445PMC
August 2017

Essential Roles of SATB1 in Specifying T Lymphocyte Subsets.

Cell Rep 2017 05;19(6):1176-1188

Laboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences (IMS), 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.04.038DOI Listing
May 2017

Novel interferon-γ enzyme-linked immunoSpot assay using activated cells for identifying hypersensitivity-inducing drug culprits.

J Dermatol Sci 2017 Jun 14;86(3):222-229. Epub 2017 Mar 14.

Department of Dermatology, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jdermsci.2017.03.007DOI Listing
June 2017

Regulatory T cells in cancer immunotherapy.

Cell Res 2017 Jan 20;27(1):109-118. Epub 2016 Dec 20.

Laboratory of Experimental Immunology, WPI Immunology Frontier Research Center, Osaka University, Suita 565-0871, Japan.

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http://dx.doi.org/10.1038/cr.2016.151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223231PMC
January 2017

ICOS Foxp3 TILs in gastric cancer are prognostic markers and effector regulatory T cells associated with Helicobacter pylori.

Int J Cancer 2017 Feb 27;140(3):686-695. Epub 2016 Oct 27.

Department of Clinical Research in Tumor Immunology, Graduate School of Medicine, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1002/ijc.30475DOI Listing
February 2017

UVB Exposure Prevents Atherosclerosis by Regulating Immunoinflammatory Responses.

Arterioscler Thromb Vasc Biol 2017 01 20;37(1):66-74. Epub 2016 Oct 20.

From the Division of Cardiovascular Medicine, Department of Internal Medicine (N.S., T. Yamashita., K.K., T.E., K.Y., T. Matsumoto, K.N., T.K., M.T., T. Mizoguchi, T.H., Y.S., K.-i.H.) and Division of Dermatology, Department of Internal Related (A.F., M.H., K.T., K.W., C.N.), Kobe University Graduate School of Medicine, Japan; Department of Medical Pharmaceutics, Kobe Pharmaceutical University, Japan (N.S.); Department of Single Molecule Imaging (T. Yamaguchi) and Department of Experimental Immunology (S.S.), World Premier International Immunology Frontier Research Center, Osaka University, Japan; Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, Japan (M.T.); and Centre d'Immunologie de Marseille-Luminy and the Centre d'Immunophénomique, UM2 Aix-Marseille Université, Marseille, France (B.M.).

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http://dx.doi.org/10.1161/ATVBAHA.116.308063DOI Listing
January 2017

The Proportion of Regulatory T Cells in Patients with Rheumatoid Arthritis: A Meta-Analysis.

PLoS One 2016 13;11(9):e0162306. Epub 2016 Sep 13.

Department of Respiratory Medicine, Allergy and Rheumatic diseases, Osaka University Graduate School of Medicine, Osaka, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0162306PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021283PMC
August 2017

Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice.

J Immunol 2016 07 10;197(2):429-40. Epub 2016 Jun 10.

Institute of Immunology and Infection Research, Ashworth Laboratories, University of Edinburgh, Edinburgh EH9 3FL, United Kingdom; and

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http://dx.doi.org/10.4049/jimmunol.1502656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932175PMC
July 2016

Two FOXP3(+)CD4(+) T cell subpopulations distinctly control the prognosis of colorectal cancers.

Nat Med 2016 06 25;22(6):679-84. Epub 2016 Apr 25.

Experimental Immunology, World Premier International Research Center (WPI), Immunology Frontier Research Center, Graduate School of Medicine, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1038/nm.4086DOI Listing
June 2016

Utility of CD127 combined with FOXP3 for identification of operational tolerance after liver transplantation.

Transpl Immunol 2016 05 20;36:1-8. Epub 2016 Apr 20.

Department of Disaster and Comprehensive Medicine, Fukushima Medical University, Fukushima 960-1295, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.trim.2016.04.005DOI Listing
May 2016

Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system.

Proc Natl Acad Sci U S A 2016 Apr 13;113(17):E2393-402. Epub 2016 Apr 13.

Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Suita 565-0871, Japan;

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http://dx.doi.org/10.1073/pnas.1604351113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855614PMC
April 2016

Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood.

Proc Natl Acad Sci U S A 2016 Apr 11;113(17):E2383-92. Epub 2016 Apr 11.

Division of Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-17177 Stockholm, Sweden;

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http://dx.doi.org/10.1073/pnas.1603892113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855592PMC
April 2016

Transcriptional and Epigenetic Control of Regulatory T Cell Development.

Prog Mol Biol Transl Sci 2015 19;136:1-33. Epub 2015 Aug 19.

Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan. Electronic address:

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http://dx.doi.org/10.1016/bs.pmbts.2015.07.011DOI Listing
November 2016

Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3high regulatory T cells in humans.

Proc Natl Acad Sci U S A 2015 Jun 26;112(23):7225-30. Epub 2015 May 26.

INSERM, U1135, Centre d'Immunologie et des Maladies Infectieuses (CIMI), 75013 Paris, France; Assistance Publique - Hôpitaux de Paris (AP-HP), Département d'Immunologie, Hôpital Pitié-Salpêtrière, 75013 Paris, France; Sorbonne Universités, Université Pierre et Marie Curie Univ Paris 06, CR7, Centre d'Immunologie et des Maladies Infectieuses (CIMI), 75013 Paris, France

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http://dx.doi.org/10.1073/pnas.1508224112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466753PMC
June 2015

Immunology. Early life Aire.

Science 2015 May 30;348(6234):506-7. Epub 2015 Apr 30.

Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1126/science.aab2998DOI Listing
May 2015

Comment on "cutting edge: epigenetic regulation of Foxp3 defines a stable population of CD4+ regulatory T cells in tumors from mice and humans".

J Immunol 2015 Apr;194(8):3533

Department of Experimental Immunology, World Premier International Immunology Frontier Research Center, Osaka University, Suita 565-0871, Japan.

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http://dx.doi.org/10.4049/jimmunol.1500248DOI Listing
April 2015

In vivo induction of T-follicular helper cells by modulation of regulatory T cell function.

Methods Mol Biol 2015 ;1291:77-85

Laboratory of Experimental Immunology, WPI Immunology Frontier Research Center, Osaka University, 3-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.

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http://dx.doi.org/10.1007/978-1-4939-2498-1_7DOI Listing
December 2015

Regulatory T cells control antigen-specific expansion of Tfh cell number and humoral immune responses via the coreceptor CTLA-4.

Immunity 2014 Dec 6;41(6):1013-25. Epub 2014 Dec 6.

Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Suita 565-0871, Japan; Department of Experimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613140044
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http://dx.doi.org/10.1016/j.immuni.2014.12.006DOI Listing
December 2014

Detection of self-reactive CD8⁺ T cells with an anergic phenotype in healthy individuals.

Science 2014 Dec;346(6216):1536-40

Experimental Immunology, Immunology Frontier Research Center (IFReC-WPI), Osaka University, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1126/science.aaa1292DOI Listing
December 2014

Interleukin-10-producing plasmablasts exert regulatory function in autoimmune inflammation.

Immunity 2014 Dec 4;41(6):1040-51. Epub 2014 Nov 4.

Laboratory for Lymphocyte Differentiation, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka 565-0871, Japan; Laboratory for Lymphocyte Differentiation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa 230-0045, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.10.016DOI Listing
December 2014

Continuous T cell receptor signals maintain a functional regulatory T cell pool.

Immunity 2014 Nov 6;41(5):722-36. Epub 2014 Nov 6.

Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany; Department of Hematology, Oncology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Straße 15, 81675 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.10.012DOI Listing
November 2014

Homeostasis of thymus-derived Foxp3+ regulatory T cells is controlled by ultraviolet B exposure in the skin.

J Immunol 2014 Dec 27;193(11):5488-97. Epub 2014 Oct 27.

Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan;

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http://www.jimmunol.org/content/193/11/5488.full.pdf
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1400985
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http://dx.doi.org/10.4049/jimmunol.1400985DOI Listing
December 2014

Epigenetic control of thymic Treg-cell development.

Eur J Immunol 2015 Jan 20;45(1):11-6. Epub 2014 Nov 20.

Department of Experimental Immunology, World Premier International Immunology Frontier Research Center, Osaka University, Suita, Japan.

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http://dx.doi.org/10.1002/eji.201444577DOI Listing
January 2015

Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease.

Science 2014 Oct;346(6207):363-8

Department of Experimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan. Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Suita 565-0871, Japan. Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency, Tokyo 102-0075, Japan.

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http://dx.doi.org/10.1126/science.1259077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554397PMC
October 2014

TREG-cell therapies for autoimmune rheumatic diseases.

Nat Rev Rheumatol 2014 Sep 1;10(9):543-51. Epub 2014 Jul 1.

Department of Experimental Immunology, WPI Immunology Frontier Research Center, Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1038/nrrheum.2014.105DOI Listing
September 2014

Comprehensive exploration of autoantibody in Behçet's disease: a novel autoantibody to claudin-1, an essential protein for tight junctions, is identified.

Joint Bone Spine 2014 Dec 29;81(6):546-8. Epub 2014 Apr 29.

Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine, Suita, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan; Core Research for Evolutionary Science and Technology (CREST), Osaka University, Suita, Osaka, Japan.

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http://dx.doi.org/10.1016/j.jbspin.2014.03.005DOI Listing
December 2014

Genetic and epigenetic basis of Treg cell development and function: from a FoxP3-centered view to an epigenome-defined view of natural Treg cells.

Immunol Rev 2014 May;259(1):192-205

Laboratory of Experimental Immunology, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan.

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http://doi.wiley.com/10.1111/imr.12174
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http://dx.doi.org/10.1111/imr.12174DOI Listing
May 2014

Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation.

Proc Natl Acad Sci U S A 2014 Apr 27;111(14):5289-94. Epub 2014 Mar 27.

Departments of Experimental Immunology and Systems Immunology, World Premier International Immunology Frontier Research Center, Osaka University, Suita 565-0871, Japan.

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http://dx.doi.org/10.1073/pnas.1312717110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986152PMC
April 2014

A promoter-level mammalian expression atlas.

Authors:
Alistair R R Forrest Hideya Kawaji Michael Rehli J Kenneth Baillie Michiel J L de Hoon Vanja Haberle Timo Lassmann Ivan V Kulakovskiy Marina Lizio Masayoshi Itoh Robin Andersson Christopher J Mungall Terrence F Meehan Sebastian Schmeier Nicolas Bertin Mette Jørgensen Emmanuel Dimont Erik Arner Christian Schmidl Ulf Schaefer Yulia A Medvedeva Charles Plessy Morana Vitezic Jessica Severin Colin A Semple Yuri Ishizu Robert S Young Margherita Francescatto Intikhab Alam Davide Albanese Gabriel M Altschuler Takahiro Arakawa John A C Archer Peter Arner Magda Babina Sarah Rennie Piotr J Balwierz Anthony G Beckhouse Swati Pradhan-Bhatt Judith A Blake Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher A Maxwell Burroughs Andrea Califano Carlo V Cannistraci Daniel Carbajo Yun Chen Marco Chierici Yari Ciani Hans C Clevers Emiliano Dalla Carrie A Davis Michael Detmar Alexander D Diehl Taeko Dohi Finn Drabløs Albert S B Edge Matthias Edinger Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Michela Fagiolini Lynsey Fairbairn Hai Fang Mary C Farach-Carson Geoffrey J Faulkner Alexander V Favorov Malcolm E Fisher Martin C Frith Rie Fujita Shiro Fukuda Cesare Furlanello Masaaki Furino Jun-ichi Furusawa Teunis B Geijtenbeek Andrew P Gibson Thomas Gingeras Daniel Goldowitz Julian Gough Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Matthias Harbers Jayson Harshbarger Akira Hasegawa Yuki Hasegawa Takehiro Hashimoto Meenhard Herlyn Kelly J Hitchens Shannan J Ho Sui Oliver M Hofmann Ilka Hoof Furni Hori Lukasz Huminiecki Kei Iida Tomokatsu Ikawa Boris R Jankovic Hui Jia Anagha Joshi Giuseppe Jurman Bogumil Kaczkowski Chieko Kai Kaoru Kaida Ai Kaiho Kazuhiro Kajiyama Mutsumi Kanamori-Katayama Artem S Kasianov Takeya Kasukawa Shintaro Katayama Sachi Kato Shuji Kawaguchi Hiroshi Kawamoto Yuki I Kawamura Tsugumi Kawashima Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura S Peter Klinken Alan J Knox Miki Kojima Soichi Kojima Naoto Kondo Haruhiko Koseki Shigeo Koyasu Sarah Krampitz Atsutaka Kubosaki Andrew T Kwon Jeroen F J Laros Weonju Lee Andreas Lennartsson Kang Li Berit Lilje Leonard Lipovich Alan Mackay-Sim Ri-ichiroh Manabe Jessica C Mar Benoit Marchand Anthony Mathelier Niklas Mejhert Alison Meynert Yosuke Mizuno David A de Lima Morais Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Efthymios Motakis Hozumi Motohashi Christine L Mummery Mitsuyoshi Murata Sayaka Nagao-Sato Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Kenichi Nakazato Erik van Nimwegen Noriko Ninomiya Hiromi Nishiyori Shohei Noma Shohei Noma Tadasuke Noazaki Soichi Ogishima Naganari Ohkura Hiroko Ohimiya Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Arnab Pain Robert Passier Margaret Patrikakis Helena Persson Silvano Piazza James G D Prendergast Owen J L Rackham Jordan A Ramilowski Mamoon Rashid Timothy Ravasi Patrizia Rizzu Marco Roncador Sugata Roy Morten B Rye Eri Saijyo Antti Sajantila Akiko Saka Shimon Sakaguchi Mizuho Sakai Hiroki Sato Suzana Savvi Alka Saxena Claudio Schneider Erik A Schultes Gundula G Schulze-Tanzil Anita Schwegmann Thierry Sengstag Guojun Sheng Hisashi Shimoji Yishai Shimoni Jay W Shin Christophe Simon Daisuke Sugiyama Takaai Sugiyama Masanori Suzuki Naoko Suzuki Rolf K Swoboda Peter A C 't Hoen Michihira Tagami Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Zuotian Tatum Mark Thompson Hiroo Toyodo Tetsuro Toyoda Elvind Valen Marc van de Wetering Linda M van den Berg Roberto Verado Dipti Vijayan Ilya E Vorontsov Wyeth W Wasserman Shoko Watanabe Christine A Wells Louise N Winteringham Ernst Wolvetang Emily J Wood Yoko Yamaguchi Masayuki Yamamoto Misako Yoneda Yohei Yonekura Shigehiro Yoshida Susan E Zabierowski Peter G Zhang Xiaobei Zhao Silvia Zucchelli Kim M Summers Harukazu Suzuki Carsten O Daub Jun Kawai Peter Heutink Winston Hide Tom C Freeman Boris Lenhard Vladimir B Bajic Martin S Taylor Vsevolod J Makeev Albin Sandelin David A Hume Piero Carninci Yoshihide Hayashizaki

Nature 2014 Mar;507(7493):462-70

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http://dx.doi.org/10.1038/nature13182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529748PMC
March 2014

CD28 signals the differential control of regulatory T cells and effector T cells.

Eur J Immunol 2014 Apr;44(4):955-7

Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1002/eji.201444513DOI Listing
April 2014

Regulatory T cells in cancer immunotherapy.

Curr Opin Immunol 2014 Apr 14;27:1-7. Epub 2014 Jan 14.

Experimental Immunology, WPI Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2013.12.005DOI Listing
April 2014

Foxp3⁺ T(reg) cells in humoral immunity.

Int Immunol 2014 Feb 9;26(2):61-9. Epub 2013 Dec 9.

Department of Experimental Immunology, WPI Immunology Frontier Research Center, Osaka University, Suita 565-0871, Osaka, Japan.

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http://dx.doi.org/10.1093/intimm/dxt060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108613PMC
February 2014

Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans.

Proc Natl Acad Sci U S A 2013 Oct 14;110(44):17945-50. Epub 2013 Oct 14.

Experimental Immunology, World Premier International Research Center, Immunology Frontier Research Center, Department of Dermatology, and Department of Hematology and Oncology, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1073/pnas.1316796110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816454PMC
October 2013