Publications by authors named "Shilin Xu"

24Publications

Follicular lymphoma-associated BTK mutations are inactivating resulting in augmented AKT activation.

Authors:
Nan Hu Fangyang Wang Tianyu Sun Zhengfan Xu Jing Zhang Denzil Bernard Shilin Xu Shaomeng Wang Mark S Kaminski Sumana Devata Tycel Phillips Sami Malek

Clin Cancer Res 2021 Jan 8. Epub 2021 Jan 8.

Med-Hematology/ Oncology, University of Michigan–Ann Arbor

View Article and Find Full Text PDF
January 2021

Computation Offloading in a Cognitive Vehicular Networks with Vehicular Cloud Computing and Remote Cloud Computing.

Authors:
Shilin Xu Caili Guo

Sensors (Basel) 2020 Nov 29;20(23). Epub 2020 Nov 29.

Beijing Laboratory of Advanced Information Networks, Beijing University of Posts and Telecommunications, Beijing 100876, China.

View Article and Find Full Text PDF
November 2020

Co-delivery of homoharringtonine and doxorubicin boosts therapeutic efficacy of refractory acute myeloid leukemia.

Authors:
Doudou Yan Hui Wei Xinning Lai Yangyang Ge Shilin Xu Jie Meng Tao Wen Jian Liu Weiqi Zhang Jianxiang Wang Haiyan Xu

J Control Release 2020 Nov 17;327:766-778. Epub 2020 Sep 17.

Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, PR China. Electronic address:

View Article and Find Full Text PDF
November 2020

Outcome of allogeneic hematopoietic stem cell transplantation for hypoplastic myelodysplastic syndrome.

Authors:
Ming Zhou Liangliang Wu Yuping Zhang Wenjian Mo Yumiao Li Xiaowei Chen Caixia Wang Shiyi Pan Shilin Xu Wei Zhou Tingfen Deng Shunqing Wang

Int J Hematol 2020 Dec 16;112(6):825-834. Epub 2020 Aug 16.

Department of Hematology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, 1 Panfu Road, Guangzhou, 510180, Guangdong, People's Republic of China.

View Article and Find Full Text PDF
December 2020

Synthetic CXCR4 Antagonistic Peptide Assembling with Nanoscaled Micelles Combat Acute Myeloid Leukemia.

Authors:
Jie Meng Yangyang Ge Haiyan Xing Hui Wei Shilin Xu Jian Liu Doudou Yan Tao Wen Min Wang Xiaocui Fang Lilusi Ma Yanlian Yang Chen Wang Jianxiang Wang Haiyan Xu

Small 2020 Aug 30;16(31):e2001890. Epub 2020 Jun 30.

Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005, China.

View Article and Find Full Text PDF
August 2020

Oxaliplatin-induced peripheral neuropathy: clinical features, mechanisms, prevention and treatment.

Authors:
Lumei Kang Yuyang Tian Shilin Xu Hongping Chen

J Neurol 2020 May 30. Epub 2020 May 30.

Department of Histology and Embryology, Medical College, Nanchang University, Bayi Road 461, Nanchang, 330006, China.

View Article and Find Full Text PDF
May 2020

Peptide-enabled receptor-binding-quantum dots for enhanced detection and migration inhibition of cancer cells.

Authors:
Ruijuan Zu Xiaocui Fang Yuchen Lin Shilin Xu Jie Meng Haiyan Xu Yanlian Yang Chen Wang

J Biomater Sci Polym Ed 2020 08 18;31(12):1604-1621. Epub 2020 May 18.

CAS Key Laboratory of Biological Effects of Nanomaterials and Nanosafety, CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, China.

View Article and Find Full Text PDF
August 2020

Discovery of M-808 as a Highly Potent, Covalent, Small-Molecule Inhibitor of the Menin-MLL Interaction with Strong Antitumor Activity.

Authors:
Shilin Xu Angelo Aguilar Liyue Huang Tianfeng Xu Ke Zheng Donna McEachern Sally Przybranowski Caroline Foster Kaitlin Zawacki Zhaomin Liu Krishnapriya Chinnaswamy Jeanne Stuckey Shaomeng Wang

J Med Chem 2020 05 27;63(9):4997-5010. Epub 2020 Apr 27.

View Article and Find Full Text PDF
May 2020

Stiffness of cationized gelatin nanoparticles is a key factor determining RNAi efficiency in myeloid leukemia cells.

Authors:
Weiqi Zhang Bo Han Xinning Lai Chen Xiao Shilin Xu Xianghui Meng Zifu Li Jie Meng Tao Wen Xiangliang Yang Jian Liu Haiyan Xu

Chem Commun (Camb) 2020 Jan 3;56(8):1255-1258. Epub 2020 Jan 3.

Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, P. R. China.

View Article and Find Full Text PDF
January 2020

Disease burden concerning hepatitis E-infected inpatients in Jiangsu province, China.

Authors:
Tingting Cui Xuefeng Zhang Qiang Wang Na Yue Mengyun Zheng Donglei Wang Chunxiao Duan Xiaoge Yu Changjun Bao Renjie Jiang Shilin Xu Zhaohu Yuan Yunke Qian Liling Chen Hui Hang Zhong Zhang Hongmin Sun Hui Jin

Vaccine 2020 01 24;38(3):673-679. Epub 2019 Oct 24.

Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing 210009, China; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China. Electronic address:

View Article and Find Full Text PDF
January 2020

A multifunctional gelatine-quaternary ammonium copolymer: An efficient material for reducing dye emission in leather tanning process by superior anionic dye adsorption.

Authors:
Shilin Xu Xinlei Niu Zhaosheng Hou Chunhong Gao Jianmei Lu Yiyi Pang Ming Fang Yao Lu Yujie Chen Joshy K S Tianduo Li Jing Xu

J Hazard Mater 2020 02 3;383:121142. Epub 2019 Sep 3.

Shandong Provincial Key Laboratory of Molecular Engineering, School of Chemistry and Pharmaceutical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, PR China. Electronic address:

View Article and Find Full Text PDF
February 2020

Tyrosine Kinase 2 (TYK2) Allosteric Inhibitors To Treat Autoimmune Diseases.

Authors:
Yu Chang Shilin Xu Ke Ding

J Med Chem 2019 10 11;62(20):8951-8952. Epub 2019 Oct 11.

International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MoE), The First Affiliated Hospital & School of Pharmacy , Jinan University , 601 Huangpu Avenue West , Guangzhou 510632 , China.

View Article and Find Full Text PDF
October 2019

Structure-Based Discovery of M-89 as a Highly Potent Inhibitor of the Menin-Mixed Lineage Leukemia (Menin-MLL) Protein-Protein Interaction.

Authors:
Angelo Aguilar Ke Zheng Tianfeng Xu Shilin Xu Liyue Huang Ester Fernandez-Salas Liu Liu Denzil Bernard Kaitlin P Harvey Caroline Foster Donna McEachern Jeanne Stuckey Krishnapriya Chinnaswamy James Delproposto Jeff W Kampf Shaomeng Wang

J Med Chem 2019 07 22;62(13):6015-6034. Epub 2019 Jun 22.

View Article and Find Full Text PDF
July 2019

Comparable Outcomes of First-Line Hematopoietic Stem Cell Transplantation from Unrelated and Matched Sibling Donors in Adult Patients with Aplastic Anemia: A Retrospective Single-Center Study.

Authors:
Yuping Zhang Liangliang Wu Wenjian Mo Ming Zhou Yumiao Li Xiaowei Chen Caixia Wang Shiyi Pan Shilin Xu Wei Zhou Ruiqing Zhou Shunqing Wang

Biol Blood Marrow Transplant 2019 08 26;25(8):1567-1575. Epub 2019 Mar 26.

Department of Hematology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China; Department of Hematology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China. Electronic address:

View Article and Find Full Text PDF
August 2019

Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of Severe Aplastic Anemia Patients with Infection: A Single-Center Retrospective Study.

Authors:
Shilin Xu Liangliang Wu Yuping Zhang Wenjian Mo Ming Zhou Yumiao Li Shiyi Pan Shunqing Wang

Biol Blood Marrow Transplant 2018 12 17;24(12):2532-2539. Epub 2018 Jul 17.

Department of Hematology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China. Electronic address:

View Article and Find Full Text PDF
December 2018

Design of the First-in-Class, Highly Potent Irreversible Inhibitor Targeting the Menin-MLL Protein-Protein Interaction.

Authors:
Shilin Xu Angelo Aguilar Tianfeng Xu Ke Zheng Liyue Huang Jeanne Stuckey Krishnapriya Chinnaswamy Denzil Bernard Ester Fernández-Salas Liu Liu Mi Wang Donna McEachern Sally Przybranowski Caroline Foster Shaomeng Wang

Angew Chem Int Ed Engl 2018 02 15;57(6):1601-1605. Epub 2018 Jan 15.

Comprehensive Cancer and Departments of Internal Medicine, Pharmacology and Medicinal Chemistry, University of Michigan, 1600 Huron Parkway, Ann Arbor, MI, 48109, USA.

View Article and Find Full Text PDF
February 2018

Resveratrol Suppresses Growth and Migration of Myelodysplastic Cells by Inhibiting the Expression of Elevated Cyclin D1 (CCND1).

Authors:
Wei Zhou Shilin Xu Yi Ying Ruiqing Zhou Xiaowei Chen

DNA Cell Biol 2017 Nov 16;36(11):966-975. Epub 2017 Oct 16.

Department of Hematology, Guangzhou First People's Hospital, Guangzhou Medical University , Guangzhou, People's Republic of China .

View Article and Find Full Text PDF
November 2017

Vitamin D receptor gene associations with pulmonary tuberculosis in a Tibetan Chinese population.

Authors:
Qunying Hu Zhengshuai Chen Guinian Liang Fangping Mo Hengxun Zhang Shilin Xu Yuhe Wang Longli Kang Tianbo Jin

BMC Infect Dis 2016 09 5;16:469. Epub 2016 Sep 5.

Key Laboratory for Basic Life Science Research of Tibet Autonomous Region, School of Medicine, Xizang Minzu University, Xianyang, Shaanxi, 712082, China.

View Article and Find Full Text PDF
September 2016

Micromonospora lycii sp. nov., a novel endophytic actinomycete isolated from wolfberry root (Lycium chinense Mill).

Authors:
Junwei Zhao Lifeng Guo Chongxi Liu Yuejing Zhang Xuejiao Guan Jiansong Li Shilin Xu Wensheng Xiang Xiangjing Wang

J Antibiot (Tokyo) 2016 Mar 28;69(3):153-8. Epub 2015 Oct 28.

School of Life Science, Key Laboratory of Agriculture Biological Functional Gene of Heilongjiang Provincial Education Committee, Northeast Agricultural University, Harbin, PR China.

View Article and Find Full Text PDF
March 2016

1-Benzyl-4-phenyl-1H-1,2,3-triazoles improve the transcriptional functions of estrogen-related receptor γ and promote the browning of white adipose.

Authors:
Shilin Xu Liufeng Mao Ping Ding Xiaoxi Zhuang Yang Zhou Lei Yu Yingxue Liu Tao Nie Tingting Xu Yong Xu Jinsong Liu Jeff Smaill Xiaomei Ren Donghai Wu Ke Ding

Bioorg Med Chem 2015 Jul 9;23(13):3751-60. Epub 2015 Apr 9.

State Key Laboratory of Respiratory Diseases, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, No. 190 Kaiyuan Avenue, Guangzhou 510530, China. Electronic address:

View Article and Find Full Text PDF
July 2015