Shih-Hwa Chiou

Shih-Hwa Chiou

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Shih-Hwa Chiou

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Morphological and Molecular Defects in Human Three-Dimensional Retinal Organoid Model of X-Linked Juvenile Retinoschisis.

Stem Cell Reports 2019 Nov 24;13(5):906-923. Epub 2019 Oct 24.

Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan; Institute of Pharmacology, National Yang-Ming University, Taipei 11221, Taiwan; School of Medicine, National Yang-Ming University, Taipei 11221, Taiwan; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei 11217, Taiwan; Genomic Research Center, Academia Sinica, Taipei 11529, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2019.09.010DOI Listing
November 2019

Induced Pluripotent Stem Cells Attenuate Endothelial Leakage in Acute Lung Injury via Tissue Inhibitor of Metalloproteinases-1 to Reduce Focal Adhesion Kinase Activity.

Stem Cells 2019 Oct 6. Epub 2019 Oct 6.

Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.

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http://dx.doi.org/10.1002/stem.3093DOI Listing
October 2019

Carboxylated nanodiamond-mediated CRISPR-Cas9 delivery of human retinoschisis mutation into human iPSCs and mouse retina.

Acta Biomater 2019 Oct 28. Epub 2019 Oct 28.

Department of Medical Research, Taipei Veterans General Hospital, Taipei, 11217, Taiwan; School of Medicine, National Yang-Ming University, Taipei, 11221, Taiwan; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, 11217, Taiwan; Institute of Clinical Medicine, National Yang-Ming University, Taipei, 11221, Taiwan; Institute of Pharmacology, National Yang-Ming University, Taipei, 11221, Taiwan; Genomic Research Center, Academia Sinica, Taipei, 11529, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2019.10.037DOI Listing
October 2019

Corrigendum to "Generation of induced pluripotent stem cells from a patient with X-linked juvenile retinoschisis" [Stem Cell Res. 29(2018): 152-156].

Stem Cell Res 2019 01;34:101388

Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan; Genomic Research Center, Academia Sinica, Taipei, Taiwan; Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S18735061193001
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http://dx.doi.org/10.1016/j.scr.2019.101388DOI Listing
January 2019

Supercontinuum source-based multi-contrast optical coherence tomography for rat retina imaging.

Biomed Opt Express 2018 Dec 12;9(12):6132-6144. Epub 2018 Nov 12.

Institute of Biophotonics, National Yang-Ming University, Taipei 112, Taiwan.

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https://www.osapublishing.org/abstract.cfm?URI=boe-9-12-6132
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http://dx.doi.org/10.1364/BOE.9.006132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6490977PMC
December 2018

Printable Graphene Oxide Micropatterns for a Bio-Subretinal Chip.

Adv Healthc Mater 2018 09 26;7(18):e1800365. Epub 2018 Jul 26.

Institute of Biomedical Engineering, College of Electrical and Computer Engineering, National Chiao Tung University, Hsinchu, 300, Taiwan.

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http://doi.wiley.com/10.1002/adhm.201800365
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http://dx.doi.org/10.1002/adhm.201800365DOI Listing
September 2018

Generation of two isogenic human induced pluripotent stem cell lines from a 15 year-old female patient with MERRF syndrome and A8344G mutation of mitochondrial DNA.

Stem Cell Res 2018 07 28;30:201-205. Epub 2018 May 28.

Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan.; Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Institute of Biomedical Sciences, Mackay Medical College, New Taipei City, Taiwan; Genomic Research Center, Academia Sinica, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2018.05.011DOI Listing
July 2018

Musashi-1 promotes chemoresistant granule formation by PKR/eIF2α signalling cascade in refractory glioblastoma.

Biochim Biophys Acta Mol Basis Dis 2018 May 24;1864(5 Pt A):1850-1861. Epub 2018 Feb 24.

School of Medicine, National Yang-Ming University, Taipei, Taiwan; Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09254439183007
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http://dx.doi.org/10.1016/j.bbadis.2018.02.017DOI Listing
May 2018

Generation of induced pluripotent stem cells from a patient with Best Dystrophy carrying 11q12.3 (BEST1 (VMD2)) mutation.

Stem Cell Res 2018 05 3;29:134-138. Epub 2018 Apr 3.

Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.scr.2018.03.019DOI Listing
May 2018

Generation of induced pluripotent stem cells from a patient with X-linked juvenile retinoschisis.

Stem Cell Res 2018 05 11;29:152-156. Epub 2018 Apr 11.

Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan; Genomic Research Center, Academia Sinica, Taipei, Taiwan; Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S18735061183010
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http://dx.doi.org/10.1016/j.scr.2018.04.005DOI Listing
May 2018

Generation of patient-specific induced pluripotent stem cells from Leber's hereditary optic neuropathy.

Stem Cell Res 2018 04 31;28:56-60. Epub 2018 Jan 31.

Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan; Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan; Genomic Research Center, Academia Sinica, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2018.01.029DOI Listing
April 2018

MicroRNA-142-3p is involved in regulation of expression in glioblastoma cells.

Cancer Manag Res 2018 12;10:775-785. Epub 2018 Apr 12.

Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital.

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http://dx.doi.org/10.2147/CMAR.S157261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903834PMC
April 2018

Arsenic trioxide-mediated suppression of miR-182-5p is associated with potent anti-oxidant effects through up-regulation of .

Oncotarget 2018 Mar 23;9(22):16028-16042. Epub 2018 Mar 23.

Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan.

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http://dx.doi.org/10.18632/oncotarget.24678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882315PMC
March 2018

Bioactivity and gene expression profiles of hiPSC-generated retinal ganglion cells in MT-ND4 mutated Leber's hereditary optic neuropathy.

Exp Cell Res 2018 02;363(2):299-309

Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2018.01.020DOI Listing
February 2018

Risk factors for myopia progression in second-grade primary school children in Taipei: a population-based cohort study.

Br J Ophthalmol 2017 12 18;101(12):1611-1617. Epub 2017 Mar 18.

Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1136/bjophthalmol-2016-309299DOI Listing
December 2017

Suppressing NF-κB and NKRF Pathways by Induced Pluripotent Stem Cell Therapy in Mice with Ventilator-Induced Lung Injury.

PLoS One 2013 26;8(6):e66760. Epub 2013 Jun 26.

Chest Department, Taipei Veterans General Hospital, Taipei, Taiwan ; Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0066760PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694116PMC
October 2017

Effects of thermosensitive chitosan-gelatin based hydrogel containing glutathione on Cisd2-deficient chondrocytes under oxidative stress.

Carbohydr Polym 2017 Oct 29;173:17-27. Epub 2017 May 29.

Institute of Biomedical Engineering, College of Engineering and College of Medicine, National Taiwan University, Taipei, Taiwan; Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Miaoli, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01448617173058
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http://dx.doi.org/10.1016/j.carbpol.2017.05.069DOI Listing
October 2017

Induced pluripotent stem cells reduce neutrophil chemotaxis via activating GRK2 in endotoxin-induced acute lung injury.

Respirology 2017 08 21;22(6):1156-1164. Epub 2017 Apr 21.

Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.

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http://dx.doi.org/10.1111/resp.13053DOI Listing
August 2017

TDP-43/HDAC6 axis promoted tumor progression and regulated nutrient deprivation-induced autophagy in glioblastoma.

Oncotarget 2017 Aug 18;8(34):56612-56625. Epub 2017 May 18.

Institute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei, Taiwan.

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http://dx.doi.org/10.18632/oncotarget.17979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593587PMC
August 2017

Energy utilization of induced pluripotent stem cell-derived cardiomyocyte in Fabry disease.

Int J Cardiol 2017 Apr 5;232:255-263. Epub 2017 Jan 5.

Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Heath Care and Management Center, Taipei Veterans General Hospital, Taipei, Taiwan; Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.01.009DOI Listing
April 2017

Advances in Laparoscopic and Robotic Gastrectomy for Gastric Cancer.

Pathol Oncol Res 2017 Jan 17;23(1):13-17. Epub 2016 Oct 17.

Division of General Surgery, Department of Surgery, Taipei Veterans General Hospital, No. 201, Sec. 2, Shipai Rd, Beitou District, Taipei City, Taiwan, 11217.

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http://dx.doi.org/10.1007/s12253-016-0131-0DOI Listing
January 2017

Induced Pluripotent Stem Cell-Derived Conditioned Medium Attenuates Acute Kidney Injury by Downregulating the Oxidative Stress-Related Pathway in Ischemia-Reperfusion Rats.

Cell Transplant 2016 30;25(3):517-30. Epub 2015 Jun 30.

Department and Institute of Physiology, National Yang-Ming University, Taipei, Taiwan.

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http://dx.doi.org/10.3727/096368915X688542DOI Listing
December 2016

Chinese herbal medicines promote hippocampal neuroproliferation, reduce stress hormone levels, inhibit apoptosis, and improve behavior in chronically stressed mice.

J Ethnopharmacol 2016 Dec 11;193:159-168. Epub 2016 Jul 11.

School of Pharmacy, National Defense Medical Center, Taipei, Taiwan, Republic of China; Research Center for Industry of Human Ecology, Chang Gung University of Science and Technology, Taoyuan, Taiwan, Republic of China; Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology, Taoyuan, Taiwan, Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2016.07.025DOI Listing
December 2016

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.

Authors:
Jonathon Torchia Brian Golbourn Shengrui Feng King Ching Ho Patrick Sin-Chan Alexandre Vasiljevic Joseph D Norman Paul Guilhamon Livia Garzia Natalia R Agamez Mei Lu Tiffany S Chan Daniel Picard Pasqualino de Antonellis Dong-Anh Khuong-Quang Aline C Planello Constanze Zeller Dalia Barsyte-Lovejoy Lucie Lafay-Cousin Louis Letourneau Mathieu Bourgey Man Yu Deena M A Gendoo Misko Dzamba Mark Barszczyk Tiago Medina Alexandra N Riemenschneider A Sorana Morrissy Young-Shin Ra Vijay Ramaswamy Marc Remke Christopher P Dunham Stephen Yip Ho-Keung Ng Jian-Qiang Lu Vivek Mehta Steffen Albrecht Jose Pimentel Jennifer A Chan Gino R Somers Claudia C Faria Lucia Roque Maryam Fouladi Lindsey M Hoffman Andrew S Moore Yin Wang Seung Ah Choi Jordan R Hansford Daniel Catchpoole Diane K Birks Nicholas K Foreman Doug Strother Almos Klekner Laszló Bognár Miklós Garami Péter Hauser Tibor Hortobágyi Beverly Wilson Juliette Hukin Anne-Sophie Carret Timothy E Van Meter Eugene I Hwang Amar Gajjar Shih-Hwa Chiou Hideo Nakamura Helen Toledano Iris Fried Daniel Fults Takafumi Wataya Chris Fryer David D Eisenstat Katrin Scheinemann Adam J Fleming Donna L Johnston Jean Michaud Shayna Zelcer Robert Hammond Samina Afzal David A Ramsay Nongnuch Sirachainan Suradej Hongeng Noppadol Larbcharoensub Richard G Grundy Rishi R Lulla Jason R Fangusaro Harriet Druker Ute Bartels Ronald Grant David Malkin C Jane McGlade Theodore Nicolaides Tarik Tihan Joanna Phillips Jacek Majewski Alexandre Montpetit Guillaume Bourque Gary D Bader Alyssa T Reddy G Yancey Gillespie Monika Warmuth-Metz Stefan Rutkowski Uri Tabori Mathieu Lupien Michael Brudno Ulrich Schüller Torsten Pietsch Alexander R Judkins Cynthia E Hawkins Eric Bouffet Seung-Ki Kim Peter B Dirks Michael D Taylor Anat Erdreich-Epstein Cheryl H Arrowsmith Daniel D De Carvalho James T Rutka Nada Jabado Annie Huang

Cancer Cell 2016 Dec;30(6):891-908

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G0A4, Canada; Department of Paediatrics, University of Toronto, Toronto, ON M5G0A4, Canada; Division of Hematology/Oncology, Hospital for Sick Children, Toronto, ON M5G1X8, Canada; Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, ON M5G1X8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500911PMC
December 2016

Human induced pluripotent stem cell and nanotechnology-based therapeutics.

Cell Transplant 2015 8;24(11):2185-95. Epub 2014 Oct 8.

Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan, ROC.

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http://dx.doi.org/10.3727/096368914X685113DOI Listing
October 2016

Evaluation of Proinflammatory Prognostic Biomarkers for Fabry Cardiomyopathy With Enzyme Replacement Therapy.

Can J Cardiol 2016 10 10;32(10):1221.e1-1221.e9. Epub 2015 Nov 10.

School of Medicine, National Yang-Ming University, Taipei, Taiwan; Divison of Cardiology and Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2015.10.033DOI Listing
October 2016

Recovery of oxidative stress-induced damage in Cisd2-deficient cardiomyocytes by sustained release of ferulic acid from injectable hydrogel.

Biomaterials 2016 10 28;103:207-218. Epub 2016 Jun 28.

Institute of Pharmacology, School of Medicine, National Yang-Ming University, No. 155, Sec. 2, Linong Street, Taipei, 112, Taiwan, ROC; Department of Medical Research, Taipei Veterans General Hospital, No. 201, Sec. 2, Shipai Rd., Beitou District, Taipei, 112, Taiwan, ROC; Genomics Research Center, Academia Sinica, No. 128 Academia Road, Section 2, Taipei, 115, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2016.06.060DOI Listing
October 2016

Oncostatin M suppresses metastasis of lung adenocarcinoma by inhibiting SLUG expression through coordination of STATs and PIASs signalings.

Oncotarget 2016 Sep;7(37):60395-60406

Institute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei, Taiwan.

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http://dx.doi.org/10.18632/oncotarget.10939DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312391PMC
September 2016

Gene Set-Based Integrative Analysis Revealing Two Distinct Functional Regulation Patterns in Four Common Subtypes of Epithelial Ovarian Cancer.

Int J Mol Sci 2016 Aug 5;17(8). Epub 2016 Aug 5.

Department of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.

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http://dx.doi.org/10.3390/ijms17081272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000670PMC
August 2016

Gene set-based integrative analysis of ovarian clear cell carcinoma.

Taiwan J Obstet Gynecol 2016 Aug;55(4):552-7

Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, National Yang-Ming University, Taipei, Taiwan; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.tjog.2016.06.004DOI Listing
August 2016

Inhibition of Src and forkhead box O1 signaling by induced pluripotent stem-cell therapy attenuates hyperoxia-augmented ventilator-induced diaphragm dysfunction.

Transl Res 2016 07 22;173:131-147.e1. Epub 2016 Mar 22.

Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Chest Department, Taipei Veterans General Hospital, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.trsl.2016.03.011DOI Listing
July 2016

Revisiting the Lamotrigine-Mediated Effect on Hippocampal GABAergic Transmission.

Int J Mol Sci 2016 Jul 22;17(7). Epub 2016 Jul 22.

Institute of Clinical Medicine, National Yang-Ming University, Taipei 112, Taiwan.

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http://dx.doi.org/10.3390/ijms17071191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964560PMC
July 2016

A Nation-Wide Cancer Registry-Based Study of Adenosquamous Carcinoma in Taiwan.

PLoS One 2015 7;10(10):e0139748. Epub 2015 Oct 7.

Division of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139748PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596803PMC
June 2016

Clinical significance of circulating plasma DNA in gastric cancer.

Int J Cancer 2016 Jun 18;138(12):2974-83. Epub 2016 Feb 18.

Division of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei City, Taiwan.

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http://dx.doi.org/10.1002/ijc.30018DOI Listing
June 2016

Thermosensitive chitosan-based hydrogel as a topical ocular drug delivery system of latanoprost for glaucoma treatment.

Carbohydr Polym 2016 Jun 3;144:390-9. Epub 2016 Mar 3.

National Yang-Ming University School of Medicine, No. 155, Sec. 2, Linong Street, Taipei 112, Taiwan; Department of Ophthalmology, Taipei Veterans General Hospital, No. 201, Sec. 2, Shipai Rd., Beitou District, Taipei 112, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.carbpol.2016.02.080DOI Listing
June 2016

Induced Pluripotent Stem Cell-conditioned Medium Suppressed Melanoma Tumorigenicity Through the Enhancement of Natural-Killer Cellular Immunity.

J Immunother 2016 May;39(4):153-9

Departments of *Chest Medicine ‡Medical Research and Education, Taipei Veterans General Hospital †School of Medicine, National Yang-Ming University §National Yang-Ming University ∥Sijhih Cathay General Hospital ¶Taipei Cancer Center, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan, ROC.

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http://dx.doi.org/10.1097/CJI.0000000000000117DOI Listing
May 2016

Comparison of the operative outcomes and learning curves between laparoscopic and robotic gastrectomy for gastric cancer.

PLoS One 2014 31;9(10):e111499. Epub 2014 Oct 31.

Division of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei City, Taiwan; School of Medicine, National Yang-Ming University, Taipei City, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111499PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216064PMC
January 2016

Thermosensitive chitosan-based hydrogels for sustained release of ferulic acid on corneal wound healing.

Carbohydr Polym 2016 Jan 3;135:308-15. Epub 2015 Sep 3.

Institute of Pharmacology, School of Medicine, National Yang-Ming University, No. 155, Sec. 2, Linong Street, Taipei 112, Taiwan, ROC; Department of Education and Research, Taipei City Hospital, No. 145, Zhengzhou Rd., Datong Dist., Taipei 103, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.carbpol.2015.08.098DOI Listing
January 2016

The correlation between miRNA and lymph node metastasis in gastric cancer.

Biomed Res Int 2015 22;2015:543163. Epub 2015 Jan 22.

Division of General Surgery, Department of Surgery, Taipei Veterans General Hospital, No. 201, Sec. 2, Shipai Road, Beitou District, Taipei City 11217, Taiwan ; School of Medicine, National Yang-Ming University, Taipei City 11221, Taiwan.

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http://dx.doi.org/10.1155/2015/543163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320935PMC
October 2015

Induced pluripotent stem cells alleviate lung injury from mesenteric ischemia-reperfusion.

J Trauma Acute Care Surg 2015 Oct;79(4):592-601

From the Institute of Clinical Medicine (C.-K.H.,H.-H.H.,S.-H.C.), Environmental and Occupational Health Science (S.-K.H.), Emergency and Critical Care Medicine (H.-C.S.,C.-H.L.), Pharmacy (S.-H.C.), or Physiology (L.-K.C.,C.-M.Y., C.-C.J.) and Department of Emergency Medicine (C.-K.H.,H.-H.H.,H.-C.S.,M.-S.H.,C.-H.L.), School of Medicine, National Yang-Ming University; Emergency Department (C.-K.H.,H.-H.H.,H.-C.S.,M.-S.H., C.-H.L.) and Department of Medical Research (S.-H.C.,C.-C.J.), Taipei Veterans General Hospital; Department of Education and Research (C.-C.J.), Taipei City Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1097/TA.0000000000000804DOI Listing
October 2015

Induced pluripotent stem cell therapy ameliorates hyperoxia-augmented ventilator-induced lung injury through suppressing the Src pathway.

PLoS One 2014 13;9(10):e109953. Epub 2014 Oct 13.

Department of Medical Research & Education, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Pharmacology, School of Medicine, National Yang-Ming University, Taipei, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0109953PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195701PMC
September 2015

Low-fluence rate, long duration photodynamic therapy in glioma mouse model using organic light emitting diode (OLED).

Photodiagnosis Photodyn Ther 2015 Sep 29;12(3):504-10. Epub 2015 Apr 29.

Institute of Biophotonics, National Yang-Ming University, Taipei 112, Taiwan; Fischell Department of Bioengineering, University of Maryland, College Park, MD 20742, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15721000150004
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http://dx.doi.org/10.1016/j.pdpdt.2015.04.007DOI Listing
September 2015

The Correlation Between RhoA Expression and Clinicopathological Characteristics in Gastric Cancer Patients After Curative Surgery.

World J Surg 2015 Sep;39(9):2289-99

Division of General Surgery, Department of Surgery, Taipei Veterans General Hospital, No. 201, Sec. 2, Shipai Rd., Beitou District, Taipei City, 11217, Taiwan.

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http://link.springer.com/10.1007/s00268-015-3095-4
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http://dx.doi.org/10.1007/s00268-015-3095-4DOI Listing
September 2015

Poly(ADP-Ribose) Polymerase 1: Cellular Pluripotency, Reprogramming, and Tumorogenesis.

Int J Mol Sci 2015 Jul 9;16(7):15531-45. Epub 2015 Jul 9.

School of Medicine, National Yang-Ming University, Taipei 112, Taiwan.

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http://www.mdpi.com/1422-0067/16/7/15531
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http://dx.doi.org/10.3390/ijms160715531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519911PMC
July 2015

Monitoring Tumor Response After Histone Deacetylase Inhibitor Treatment Using 3'-Deoxy-3'-[18F]-fluorothymidine PET.

Mol Imaging Biol 2015 Jun;17(3):394-402

Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan.

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http://dx.doi.org/10.1007/s11307-014-0774-8DOI Listing
June 2015

Lin28B/Let-7 Regulates Expression of Oct4 and Sox2 and Reprograms Oral Squamous Cell Carcinoma Cells to a Stem-like State.

Cancer Res 2015 Jun 9;75(12):2553-65. Epub 2015 Apr 9.

Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan. Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan. School of Medicine, National Yang-Ming University, Taipei, Taiwan. Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan. Genomics Research Center, Academia Sinica, Taipei, Taiwan.

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http://cancerres.aacrjournals.org/content/75/12/2553.full.pd
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-14-2215DOI Listing
June 2015

Over-expression of cofilin-1 suppressed growth and invasion of cancer cells is associated with up-regulation of let-7 microRNA.

Biochim Biophys Acta 2015 May 15;1852(5):851-61. Epub 2015 Jan 15.

Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan; Biophotonics & Molecular Imaging Research Center (BMIRC), National Yang-Ming University, Taipei, Taiwan. Electronic address:

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May 2015

Demethoxycurcumin-carrying chitosan-antibody core-shell nanoparticles with multitherapeutic efficacy toward malignant A549 lung tumor: from in vitro characterization to in vivo evaluation.

Mol Pharm 2015 Apr 19;12(4):1242-9. Epub 2015 Mar 19.

†Nano-Bioengineering Lab, Department of Material Science and Engineering, BioICT Consortium, National Chiao Tung University, Hsinchu 301, Taiwan.

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April 2015

Expression profile of MicroRNAs in gram-negative bacterial sepsis.

Shock 2015 Feb;43(2):121-7

*Institute of Clinical Medicine, and †Department of Emergency Medicine, School of Medicine, National Yang-Ming University; ‡Emergency Department, Taipei Veterans General Hospital; §Institute of Environmental and Occupational Health Sciences, ∥Institute of Emergency and Critical Care Medicine, and ¶Institute of Pharmacy, School of Medicine, National Yang-Ming University; **Department of Medical Research, Taipei Veterans General Hospital; ††Institute of Physiology, School of Medicine, National Yang-Ming University; and ‡‡Department of Education and Research, Taipei City Hospital, Taipei, Taiwan.

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February 2015

Synergistic effects of carboxymethyl-hexanoyl chitosan, cationic polyurethane-short branch PEI in miR122 gene delivery: accelerated differentiation of iPSCs into mature hepatocyte-like cells and improved stem cell therapy in a hepatic failure model.

Acta Biomater 2015 Feb 21;13:228-44. Epub 2014 Nov 21.

Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan; Division of Radiation Oncology, Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2014.11.018DOI Listing
February 2015

Induced pluripotent stem cells without c-Myc ameliorate retinal oxidative damage via paracrine effects and reduced oxidative stress in rats.

J Ocul Pharmacol Ther 2014 Nov 14;30(9):757-70. Epub 2014 Aug 14.

1 Department of Ophthalmology, Taipei City Hospital Zhongxiao Branch , Taipei City, Taiwan .

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http://www.liebertpub.com/doi/10.1089/jop.2014.0020
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220707PMC
November 2014

Sustained delivery of latanoprost by thermosensitive chitosan-gelatin-based hydrogel for controlling ocular hypertension.

Acta Biomater 2014 Oct 7;10(10):4360-6. Epub 2014 Jun 7.

National Yang-Ming University School of Medicine, Taipei, Taiwan; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan. Electronic address:

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October 2014

A temperature-induced and shear-reversible assembly of latanoprost-loaded amphiphilic chitosan colloids: characterization and in vivo glaucoma treatment.

Acta Biomater 2014 Jul 28;10(7):3188-96. Epub 2014 Mar 28.

Department of Materials Science and Engineering, BioICT Consortium, National Chiao Tung University, 1001 Ta-Hseuh Road, Hsinchu, Taiwan 300, ROC. Electronic address:

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July 2014

Comparison of clinicopathological characteristics and prognosis between early and late recurrence after curative surgery for colorectal cancer.

Am J Surg 2014 Jun 10;207(6):922-30. Epub 2013 Nov 10.

Division of Colorectal Surgery, Department of Surgery, Taipei Veterans General Hospital, 201 Section 2, Shih-Pai Road, Taipei 11217, Taiwan; Department of Surgery, National Yang-Ming University, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.amjsurg.2013.08.035DOI Listing
June 2014

Mesoporous silica nanoparticles: a potential platform for generation of induced pluripotent stem cells?

Nanomedicine (Lond) 2014 Apr;9(4):377-80

Institute of Pharmacology, National Yang-Ming University, Taipei 112, Taiwan.

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https://www.futuremedicine.com/doi/10.2217/nnm.14.9
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April 2014

Aspirin attenuates vinorelbine-induced endothelial inflammation via modulating SIRT1/AMPK axis.

Biochem Pharmacol 2014 Mar 15;88(2):189-200. Epub 2013 Dec 15.

Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan; Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2013.12.005DOI Listing
March 2014

Pulsed-focused ultrasound enhances boron drug accumulation in a human head and neck cancer xenograft-bearing mouse model.

Mol Imaging Biol 2014 Feb;16(1):95-101

Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, No.155, Sec.2, Li-Nong St, 11217, Taipei, Taiwan.

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http://dx.doi.org/10.1007/s11307-013-0675-2DOI Listing
February 2014

Maintenance of the stemness in CD44(+) HCT-15 and HCT-116 human colon cancer cells requires miR-203 suppression.

Stem Cell Res 2014 Jan 2;12(1):86-100. Epub 2013 Oct 2.

Institute of Biopharmaceutical Sciences, National Yang-Ming University, Taiwan. Electronic address:

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January 2014

Induced pluripotent stem cells without c-Myc reduce airway responsiveness and allergic reaction in sensitized mice.

Transplantation 2013 Dec;96(11):958-65

1 Department of Medical Research & Education, Taipei Veterans General Hospital, Taipei, Taiwan. 2 School of Medicine, National Yang-Ming University, Taipei, Taiwan. 3 Department of Medicine, Tri-Service General Hospital, Taipei, Taiwan. 4 Department of Pediatrics, Taipei Veterans General Hospital, Taipei, Taiwan. 5 Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan. 6 Address correspondence to: Ching-Feng Huang, M.D., Ph.D., Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, No. 325, Section 2, Cheng-Gong Road, Neihu District, Taipei 114, Taiwan.

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December 2013

Epigenetic regulation of the miR142-3p/interleukin-6 circuit in glioblastoma.

Mol Cell 2013 Dec;52(5):693-706

Institute of Pharmacology, National Yang-Ming University, Taipei 112, Taiwan; Institute of Clinical Medicine, National Yang-Ming University, Taipei 112, Taiwan; School of Medicine, National Yang-Ming University, Taipei 112, Taiwan; Cancer Research Center, National Yang-Ming University, Taipei 112, Taiwan; Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei 112, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2013.11.009DOI Listing
December 2013

Nonviral cell labeling and differentiation agent for induced pluripotent stem cells based on mesoporous silica nanoparticles.

ACS Nano 2013 Oct 30;7(10):8423-40. Epub 2013 Sep 30.

Department of Chemistry, National Taiwan University , Taipei 106, Taiwan.

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http://dx.doi.org/10.1021/nn401418nDOI Listing
October 2013

Molecular and survival differences between familial and sporadic gastric cancers.

Biomed Res Int 2013 5;2013:396272. Epub 2013 Mar 5.

Division of General Surgery, Department of Surgery, Taipei Veterans General Hospital, 201 Section 2, Shih-Pai Road, Taipei 11217, Taiwan.

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http://www.hindawi.com/journals/bmri/2013/396272/
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603157PMC
September 2013

Enhanced cell growth and tumorigenicity of rat glioma cells by stable expression of human CD133 through multiple molecular actions.

Glia 2013 Sep 6;61(9):1402-17. Epub 2013 Jul 6.

Institute of Life Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan.

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http://dx.doi.org/10.1002/glia.22521DOI Listing
September 2013

Targeting cancer stem cells: emerging role of Nanog transcription factor.

Onco Targets Ther 2013 Sep 4;6:1207-20. Epub 2013 Sep 4.

Institute of Biochemistry and Molecular Biology, National Yang Ming University, Taipei, Taiwan.

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http://dx.doi.org/10.2147/OTT.S38114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772775PMC
September 2013

Impact of body mass index on postoperative outcome of advanced gastric cancer after curative surgery.

J Gastrointest Surg 2013 Aug 29;17(8):1382-91. Epub 2013 May 29.

Division of General Surgery, Department of Surgery, Taipei Veterans General Hospital, 201 Section 2 Shih-Pai Road, Taipei, 11217, Taiwan.

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August 2013

Transplantation of induced pluripotent stem cells without C-Myc attenuates retinal ischemia and reperfusion injury in rats.

Exp Eye Res 2013 Aug 28;113:49-59. Epub 2013 May 28.

The Department of Ophthalmology, Taipei City Hospital Zhongxiao Branch, Taipei, Taiwan.

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August 2013

Correlation of microRNA-145 levels and clinical severity of pterygia.

Ocul Surf 2013 Apr 29;11(2):133-8. Epub 2013 Jan 29.

Department of Ophthalmology, National Defense Medical Center, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.jtos.2012.12.001DOI Listing
April 2013