Publications

Progressive hypofractionated carbon-ion radiotherapy for hepatocellular carcinoma: Combined analyses of 2 prospective trials.
Cancer 2017 Oct 29;123(20):3955-3965. Epub 2017 Jun 29.
Hospital of the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

Dose escalation study with respiratory-gated carbon-ion scanning radiotherapy using a simultaneous integrated boost for pancreatic cancer: simulation with four-dimensional computed tomography.
Br J Radiol 2017 Apr 9;90(1072):20160790. Epub 2017 Feb 9.
1 Hospital of the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

Late sacral recurrence of rectal cancer treated by heavy ion radiotherapy: a case report.
Surg Case Rep 2016 Dec 10;2(1):109. Epub 2016 Oct 10.
Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.



Mechanical prophylaxis is a heparin-independent risk for anti-platelet factor 4/heparin antibody formation after orthopedic surgery.
Blood 2016 Feb 9;127(8):1036-43. Epub 2015 Dec 9.
Japanese National Hospital Organization (NHO)-Evidence-Based Medicine Study Group for the Clinical Study of Prevention and Actual Situation of Venous Thromboembolism After Total Arthroplasty, Tokyo, Japan; Department of Orthopedic Surgery, NHO Nagasaki Medical Center, Nagasaki, Japan.

Carbon-Ion Irradiation Suppresses Migration and Invasiveness of Human Pancreatic Carcinoma Cells MIAPaCa-2 via Rac1 and RhoA Degradation.
Int J Radiat Oncol Biol Phys 2015 Sep 14;93(1):173-80. Epub 2015 May 14.
Advanced Radiation Biology Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba, Japan. Electronic address:

Short-term effects of highly-bioavailable curcumin for treating knee osteoarthritis: a randomized, double-blind, placebo-controlled prospective study.
J Orthop Sci 2014 Nov 13;19(6):933-9. Epub 2014 Oct 13.
Department of Orthopedic Surgery, National Hospital Organization, Kyoto Medical Center, 1-1 Fukakusa Mukaihata-cho Fushimi-ku, Kyoto, 612-8555, Japan,


Nitric oxide increases the invasion of pancreatic cancer cells via activation of the PI3K-AKT and RhoA pathways after carbon ion irradiation.
FEBS Lett 2014 Aug 11;588(17):3240-50. Epub 2014 Jul 11.
Advanced Radiation Biology Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba 263-8555, Japan. Electronic address:







11C-methionine-PET for evaluation of carbon ion radiotherapy in patients with pelvic recurrence of rectal cancer.
Mol Imaging Biol 2008 Nov-Dec;10(6):374-80. Epub 2008 Aug 5.
Diagnostic Imaging, Molecular Imaging Center, National Institute of Radiological Sciences, Anagawa 4-9-1, Inageku, Chiba, Japan.


Identification of twinfilin-2 as a factor involved in neurite outgrowth by RNAi-based screen.
Biochem Biophys Res Commun 2007 Nov 25;363(4):926-30. Epub 2007 Sep 25.
Research Institute for Cell Engineering (RICE), National Institute of Advanced Industrial Science and Technology (AIST), Aomi 2-41-6, Kohtoh-ku, Tokyo 135-0064, Japan.

Dose escalation study of carbon ion radiotherapy for locally advanced carcinoma of the uterine cervix.
Int J Radiat Oncol Biol Phys 2006 Jun 19;65(2):388-97. Epub 2006 Apr 19.
Research Center Hospital for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba, Japan.


A novel mutagen, 2-(5-hydroxy-4,6-dinitroindolyl) ethanol, formed in the reaction between 5-hydroxytryptamine and nitrite under acid conditions, especially in the presence of L-cysteine.
Mutat Res 2005 Dec 22;588(2):172-6. Epub 2005 Nov 22.
Graduate School of Nutritional and Environmental Sciences and 21st COE Program, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan.

On-chip transfection of PC12 cells based on the rational understanding of the role of ECM molecules: efficient, non-viral transfection of PC12 cells using collagen IV.
Neurosci Lett 2005 Apr 7;378(1):40-3. Epub 2005 Jan 7.
Research Institute of Cell Engineering, National Institute of Advanced Industrial Science and Technology (AIST), Nakouji 3-11-46, Amagasaki, Hyogo 661-0974, Japan.


Results of the first prospective study of carbon ion radiotherapy for hepatocellular carcinoma with liver cirrhosis.
Int J Radiat Oncol Biol Phys 2004 Aug;59(5):1468-76
Research Center Hospital for Charged Particle Therapy, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba-shi 263-8555, Japan.


Analysis of non-genetic risk factors for adverse skin reactions to radiotherapy among 284 breast cancer patients.
Breast Cancer 2006 ;13(3):300-7
RadGenomics Project, Frontier Research Center, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba-shi, Chiba-ken 263-8555, Japan.



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