Publications

Progressive hypofractionated carbon-ion radiotherapy for hepatocellular carcinoma: Combined analyses of 2 prospective trials.
Cancer 2017 Jun 29. Epub 2017 Jun 29.
Hospital of the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

Dose escalation study with respiratory-gated carbon-ion scanning radiotherapy using a simultaneous integrated boost for pancreatic cancer: simulation with four-dimensional computed tomography.
Br J Radiol 2017 Apr 9;90(1072):20160790. Epub 2017 Feb 9.
1 Hospital of the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

The Immunoregulatory Potential of Particle Radiation in Cancer Therapy.
Front Immunol 2017 6;8:99. Epub 2017 Feb 6.
Trento Institute for Fundamental Physics and Applications-National Institute for Nuclear Physics (TIFPA-INFN), University of Trento, Trentino, Italy; Department of Physics, University Federico II, Naples, Italy.

Late sacral recurrence of rectal cancer treated by heavy ion radiotherapy: a case report.
Surg Case Rep 2016 Dec 10;2(1):109. Epub 2016 Oct 10.
Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.




Mechanical prophylaxis is a heparin-independent risk for anti-platelet factor 4/heparin antibody formation after orthopedic surgery.
Blood 2016 Feb 9;127(8):1036-43. Epub 2015 Dec 9.
Japanese National Hospital Organization (NHO)-Evidence-Based Medicine Study Group for the Clinical Study of Prevention and Actual Situation of Venous Thromboembolism After Total Arthroplasty, Tokyo, Japan; Department of Orthopedic Surgery, NHO Nagasaki Medical Center, Nagasaki, Japan.

Carbon-Ion Irradiation Suppresses Migration and Invasiveness of Human Pancreatic Carcinoma Cells MIAPaCa-2 via Rac1 and RhoA Degradation.
Int J Radiat Oncol Biol Phys 2015 Sep 14;93(1):173-80. Epub 2015 May 14.
Advanced Radiation Biology Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba, Japan. Electronic address:

Short-term effects of highly-bioavailable curcumin for treating knee osteoarthritis: a randomized, double-blind, placebo-controlled prospective study.
J Orthop Sci 2014 Nov 13;19(6):933-9. Epub 2014 Oct 13.
Department of Orthopedic Surgery, National Hospital Organization, Kyoto Medical Center, 1-1 Fukakusa Mukaihata-cho Fushimi-ku, Kyoto, 612-8555, Japan,


Nitric oxide increases the invasion of pancreatic cancer cells via activation of the PI3K-AKT and RhoA pathways after carbon ion irradiation.
FEBS Lett 2014 Aug 11;588(17):3240-50. Epub 2014 Jul 11.
Advanced Radiation Biology Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba 263-8555, Japan. Electronic address:








11C-methionine-PET for evaluation of carbon ion radiotherapy in patients with pelvic recurrence of rectal cancer.
Mol Imaging Biol 2008 Nov-Dec;10(6):374-80. Epub 2008 Aug 5.
Diagnostic Imaging, Molecular Imaging Center, National Institute of Radiological Sciences, Anagawa 4-9-1, Inageku, Chiba, Japan.


Identification of twinfilin-2 as a factor involved in neurite outgrowth by RNAi-based screen.
Biochem Biophys Res Commun 2007 Nov 25;363(4):926-30. Epub 2007 Sep 25.
Research Institute for Cell Engineering (RICE), National Institute of Advanced Industrial Science and Technology (AIST), Aomi 2-41-6, Kohtoh-ku, Tokyo 135-0064, Japan.


Analysis of non-genetic risk factors for adverse skin reactions to radiotherapy among 284 breast cancer patients.
Breast Cancer 2006 ;13(3):300-7
RadGenomics Project, Frontier Research Center, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba-shi, Chiba-ken 263-8555, Japan.


Dose escalation study of carbon ion radiotherapy for locally advanced carcinoma of the uterine cervix.
Int J Radiat Oncol Biol Phys 2006 Jun 19;65(2):388-97. Epub 2006 Apr 19.
Research Center Hospital for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba, Japan.


A novel mutagen, 2-(5-hydroxy-4,6-dinitroindolyl) ethanol, formed in the reaction between 5-hydroxytryptamine and nitrite under acid conditions, especially in the presence of L-cysteine.
Mutat Res 2005 Dec 22;588(2):172-6. Epub 2005 Nov 22.
Graduate School of Nutritional and Environmental Sciences and 21st COE Program, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan.

On-chip transfection of PC12 cells based on the rational understanding of the role of ECM molecules: efficient, non-viral transfection of PC12 cells using collagen IV.
Neurosci Lett 2005 Apr 7;378(1):40-3. Epub 2005 Jan 7.
Research Institute of Cell Engineering, National Institute of Advanced Industrial Science and Technology (AIST), Nakouji 3-11-46, Amagasaki, Hyogo 661-0974, Japan.


Results of the first prospective study of carbon ion radiotherapy for hepatocellular carcinoma with liver cirrhosis.
Int J Radiat Oncol Biol Phys 2004 Aug;59(5):1468-76
Research Center Hospital for Charged Particle Therapy, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba-shi 263-8555, Japan.

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