Publications by authors named "Shigeki Umemura"

82Publications

Downregulation of CYLD promotes IFN-γ mediated PD-L1 expression in thymic epithelial tumors.

Lung Cancer 2020 09 22;147:221-228. Epub 2020 Jul 22.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20057, USA; Meyer Cancer Center, Weill Cornel Medicine, NY, USA. Electronic address:

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September 2020

Salvage chemoradiotherapy with cisplatin and vinorelbine for postoperative locoregional recurrence of non-small cell lung cancer.

Medicine (Baltimore) 2017 Nov;96(47):e8635

Department of Thoracic Oncology Department of Radiation Oncology Department of Thoracic Surgery, National Cancer Center, Kashiwa, Japan.

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November 2017

Impact of denosumab use on the survival of untreated non-squamous non-small cell lung cancer patients with bone metastases.

J Cancer Res Clin Oncol 2017 Jun 20;143(6):1075-1082. Epub 2017 Feb 20.

Department of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-0882, Japan.

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June 2017

Clinical Impact of Gastric Acid-Suppressing Medication Use on the Efficacy of Erlotinib and Gefitinib in Patients With Advanced Non-Small-Cell Lung Cancer Harboring EGFR Mutations.

Clin Lung Cancer 2016 09 5;17(5):412-418. Epub 2016 Feb 5.

Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan; Juntendo University Graduate School of Medicine, Tokyo, Japan.

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September 2016

Unique intravascular tumor microenvironment predicting recurrence of lung squamous cell carcinoma.

J Cancer Res Clin Oncol 2016 Mar 31;142(3):593-600. Epub 2015 Oct 31.

Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, 277-8577, Japan.

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March 2016

Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma.

J Biol Chem 2015 Jul 28;290(28):17495-504. Epub 2015 May 28.

From the Division of Translational Research, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba 277-8577, Japan, the Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba 277-8561.

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July 2015

Second-line docetaxel for patients with platinum-refractory advanced non-small cell lung cancer and interstitial pneumonia.

Cancer Chemother Pharmacol 2015 Jul 15;76(1):69-74. Epub 2015 May 15.

Department of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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July 2015

Docetaxel for platinum-refractory advanced thymic carcinoma.

Jpn J Clin Oncol 2015 Jul 2;45(7):665-9. Epub 2015 Apr 2.

Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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July 2015

Genomic profiling of small-cell lung cancer: the era of targeted therapies.

Jpn J Clin Oncol 2015 Jun 10;45(6):513-9. Epub 2015 Feb 10.

Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa.

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June 2015

Therapeutic priority of the PI3K/AKT/mTOR pathway in small cell lung cancers as revealed by a comprehensive genomic analysis.

J Thorac Oncol 2014 Sep;9(9):1324-31

*Division of Thoracic Oncology, National Cancer Center Hospital East; †Exploratory Oncology Research and Clinical Trial Center, National Cancer Center; ‡Pathology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East; §Division of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Japan; and ‖Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.

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September 2014

Low-dose irinotecan as a second-line chemotherapy for recurrent small cell lung cancer.

Jpn J Clin Oncol 2014 Sep 23;44(9):846-51. Epub 2014 Jul 23.

Department of Thoracic Oncology, National Cancer Center Hospital East, Chiba, Japan.

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September 2014

Protective effect of magnesium preloading on cisplatin-induced nephrotoxicity: a retrospective study.

Jpn J Clin Oncol 2014 Apr 5;44(4):346-54. Epub 2014 Feb 5.

*Division of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan.

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April 2014

Aldehyde dehydrogenase 1 expression in cancer cells could have prognostic value for patients with non-small cell lung cancer who are treated with neoadjuvant therapy: identification of prognostic microenvironmental factors after chemoradiation.

Pathol Int 2013 Dec;63(12):599-606

Division of Pathology, Research Center for Innovative Oncology, National Cancer Center, Hospital East, Kashiwa, Chiba, Japan; Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan; Juntendo University Graduate School of Medicine, Tokyo, Japan.

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December 2013

Identification of prognostic immunophenotypic features in cancer stromal cells of high-grade neuroendocrine carcinomas of the lung.

J Cancer Res Clin Oncol 2013 Nov 7;139(11):1869-78. Epub 2013 Sep 7.

Pathology Division, Department of Pathology, Research Center for Innovative Oncology, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa-City, Chiba, 277-8577, Japan.

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November 2013

Solid predominant histology predicts EGFR tyrosine kinase inhibitor response in patients with EGFR mutation-positive lung adenocarcinoma.

J Cancer Res Clin Oncol 2013 Oct 22;139(10):1691-700. Epub 2013 Aug 22.

Division of Pathology, Research Center for Innovative Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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October 2013

Safety and efficacy of platinum agents plus etoposide for patients with small cell lung cancer with interstitial lung disease.

Anticancer Res 2013 Mar;33(3):1175-9

Division of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan.

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March 2013

Renal toxicity caused by brand-name versus generic cisplatin: a comparative analysis.

Jpn J Clin Oncol 2013 Apr 26;43(4):390-5. Epub 2013 Feb 26.

Division of Thoracic Oncology, National Cancer Center Hospital East, Chiba, Japan.

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April 2013

Cavitary pulmonary involvement of diffuse large B-cell lymphoma transformed from extra nodal marginal zone B-cell lymphoma MALT type.

Clin J Gastroenterol 2011 Dec 4;4(6):401-6. Epub 2011 Oct 4.

Department of Respiratory Medicine, Okayama University Hospital, 2-5-1 Shikata-cho, Okayama, 700-8558, Japan.

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December 2011

Variant angina pectoris associated with FOLFOX4 therapy.

World J Gastrointest Oncol 2011 Nov;3(11):165-8

Hiromichi Yamane, Shigeki Umemura, Toshimitsu Suwaki, Haruhito Kamei, Division of Clinical Oncology, Sumitomo-Besshi Hospital Cancer Center, 3-1Ohji-cho, Niihama, Ehime 792-8543, Japan.

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November 2011

Interstitial lung disease associated with gemcitabine treatment in patients with non-small-cell lung cancer and pancreatic cancer.

J Cancer Res Clin Oncol 2011 Oct 5;137(10):1469-75. Epub 2011 Aug 5.

Department of Clinical Oncology, Sumitomo Besshi Hospital, 3-1 Ohji-cho, Niihama, 792-8543, Japan.

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October 2011

An oral fluoropyrimidine agent S-1 induced interstitial lung disease: A case report.

World J Clin Oncol 2011 Jul;2(7):299-302

Hiromichi Yamane, Masahide Kinugawa, Shigeki Umemura, Yasuhiro Shiote, Kenichiro Kudo, Toshimitsu Suwaki, Haruhito Kamei, Division of Clinical Oncology, Sumitomo-Besshi Hospital Cancer Center, 3-1 Ohji-cho, Niihama, Ehime 792-8543, Japan.

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July 2011

Triplet chemotherapy with cisplatin, docetaxel, and irinotecan for patients with recurrent or refractory non-small cell lung cancer.

Acta Med Okayama 2010 Feb;64(1):33-7

Department of Hematology, Oncology, and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University Hospital, Okayama 700-8558, Japan.

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February 2010

Centrally located squamous cell carcinoma of the lung mimicking endobronchial tuberculosis.

J Thorac Oncol 2009 Sep;4(9):1178-9

Division of Clinical Oncology, Sumitomo-Besshi Hospital Cancer Center, Sumitomo-Besshi Hospital, Niihama, Japan.

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September 2009

Efficacy of a lumbo-peritoneal shunt for meningeal carcinomatosis refractory to gefitinib treatment.

Anticancer Res 2009 Jul;29(7):2759-60

Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.

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July 2009

Asymptomatic colonic metastases from primary squamous cell carcinoma of the lung with a positive fecal occult blood test.

World J Gastroenterol 2008 Sep;14(35):5481-3

Department of Internal Medicine, Sumitomo Besshi Hospital, 3-1 Ohji-cho, Niihama, Japan.

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September 2008

Aberrant promoter hypermethylation in serum DNA from patients with silicosis.

Carcinogenesis 2008 Sep 16;29(9):1845-9. Epub 2008 Jul 16.

Department of Hematology, Oncology and Respiratory Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 7008558, Japan.

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September 2008

Remarkable shrinkage of sarcomatoid renal cell carcinoma with single-agent gemcitabine.

Anticancer Drugs 2008 Apr;19(4):431-3

Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

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April 2008

Radiation necrosis mimicking progressive brain metastasis in a patient with non-small cell lung cancer.

J Thorac Oncol 2007 Aug;2(8):762-3

Department of Hematology, Oncology, and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences & Okayama University Hospital, Okayama, Japan.

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August 2007

Serum level of arginine-vasopressin influences the prognosis of extensive-disease small-cell lung cancer.

J Cancer Res Clin Oncol 2007 Aug 17;133(8):519-24. Epub 2007 Mar 17.

Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.

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August 2007

A phase I study of 3-day topotecan and cisplatin in elderly patients with small-cell lung cancer.

Cancer Chemother Pharmacol 2006 Jun 6;57(6):755-60. Epub 2005 Oct 6.

Department of Respiratory Medicine, National Hospital Organization Okayama Medical Center, 1711-1 Tamasu, Okayama 701-1192, Japan.

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June 2006