Publications by authors named "Shigehisa Kitano"

65Publications

Correlation between the expression of folate receptor alpha (FRα) and clinicopathological features in patients with lung adenocarcinoma.

Lung Cancer 2020 07 11;145:152-157. Epub 2020 May 11.

Department of Diagnostic Pathology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2020.05.002DOI Listing
July 2020

Neutrophil-to-lymphocyte ratio and histological type might predict clinical responses to eriburin-based treatment in patients with metastatic breast cancer.

Breast Cancer 2020 Jul 27;27(4):732-738. Epub 2020 Feb 27.

Department of Breast Oncology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

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http://dx.doi.org/10.1007/s12282-020-01069-0DOI Listing
July 2020

CD4 T-cell Immunity in the Peripheral Blood Correlates with Response to Anti-PD-1 Therapy.

Cancer Immunol Res 2020 03 23;8(3):334-344. Epub 2019 Dec 23.

Division of Respiratory Medicine, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.

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http://dx.doi.org/10.1158/2326-6066.CIR-19-0574DOI Listing
March 2020

Improved survival among patients enrolled in oncology phase 1 trials in recent decades.

Cancer Chemother Pharmacol 2020 02 19;85(2):449-459. Epub 2019 Nov 19.

Department of Experimental Therapeutics, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1007/s00280-019-03992-2DOI Listing
February 2020

Impact of low-dose anti-thymocyte globulin on immune reconstitution after allogeneic hematopoietic cell transplantation.

Int J Hematol 2020 Jan 22;111(1):120-130. Epub 2019 Oct 22.

Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-0016, Japan.

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http://dx.doi.org/10.1007/s12185-019-02756-1DOI Listing
January 2020

[Ⅲ.Cross-Organ Developmental Status and Challenges of Immune Checkpoint Inhibitors].

Authors:
Shigehisa Kitano

Gan To Kagaku Ryoho 2019 08;46(8):1249-1257

Dept. of Experimental Therapeutics, National Cancer Center Hospital.

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August 2019

[Clinical Significance of Ipilimumab and the Combination Therapy as Immune Checkpoint Inhibitor].

Gan To Kagaku Ryoho 2019 Jun;46(6):1011-1015

Dept. of Dermatologic Oncology, National Cancer Center Hospital.

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June 2019

Immunotherapy for genitourinary tumors.

Int J Urol 2019 03 1;26(3):326-333. Epub 2019 Feb 1.

Department of Experimental Therapeutics, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1111/iju.13902DOI Listing
March 2019

Biomarkers for Immune Checkpoint Inhibitors in Melanoma.

Front Oncol 2018 18;8:270. Epub 2018 Jul 18.

Department of Experimental Therapeutics, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.3389/fonc.2018.00270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058029PMC
July 2018

Tumor-associated CD204 M2 macrophages are unfavorable prognostic indicators in uterine cervical adenocarcinoma.

Cancer Sci 2018 Mar 2;109(3):863-870. Epub 2018 Feb 2.

Division of Pathology and Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1111/cas.13476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834786PMC
March 2018

Diagnostic significance of intratumoral CD8+ tumor-infiltrating lymphocytes in medullary carcinoma.

Hum Pathol 2017 12 6;70:129-138. Epub 2017 Nov 6.

Department of Breast Oncology, Juntendo University School of Medicine, Tokyo 1138421, Japan.

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http://dx.doi.org/10.1016/j.humpath.2017.10.020DOI Listing
December 2017

[Combination Therapy of Immune Checkpoint Inhibitors].

Authors:
Shigehisa Kitano

Gan To Kagaku Ryoho 2017 Sep;44(9):727-732

Dept. of Experimental Therapeutics, National Cancer Center Hospital.

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September 2017

Development of immune checkpoint inhibitors.

Authors:
Shigehisa Kitano

Rinsho Ketsueki 2017 ;58(8):966-976

Department of Experimental Therapeutics, National Cancer Center Hospital.

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http://dx.doi.org/10.11406/rinketsu.58.966DOI Listing
December 2017

Large-scale comprehensive immunohistochemical biomarker analyses in esophageal squamous cell carcinoma.

J Cancer Res Clin Oncol 2017 Nov 29;143(11):2351-2361. Epub 2017 Jul 29.

Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://dx.doi.org/10.1007/s00432-017-2482-7DOI Listing
November 2017

[III. Recent Clinical Development of Cancer Immunotherapy and Speculation for Bone and Soft Tissue Tumors].

Authors:
Shigehisa Kitano

Gan To Kagaku Ryoho 2017 Mar;44(3):222-226

Dept. of Experimental Therapeutics, National Cancer Center Hospital.

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March 2017

Do all patients in the phase I oncology trials need to be hospitalized? Domestic but outstanding issues for globalization of drug development in Japan.

Int J Clin Oncol 2017 Aug 14;22(4):780-785. Epub 2017 Mar 14.

Department of Experimental Therapeutics, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1007/s10147-017-1108-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533862PMC
August 2017

Anti-PD-1 antibody and anti-PD-Li antibody -from basic and clinic-.

Authors:
Shigehisa Kitano

Nihon Rinsho 2017 02;75(2):201-207

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February 2017

Development of immune checkpoint inhibitor in colorectal cancer.

Authors:
Shigehisa Kitano

Nihon Rinsho 2016 11;74(11):1818-1820

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November 2016

Phase 1 study of abemaciclib, an inhibitor of CDK 4 and 6, as a single agent for Japanese patients with advanced cancer.

Cancer Chemother Pharmacol 2016 Aug 16;78(2):281-8. Epub 2016 Jun 16.

Department of Experimental Therapeutics, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1007/s00280-016-3085-8DOI Listing
August 2016

Enhancement of antitumor effect by peptide vaccine therapy in combination with anti-CD4 antibody: Study in a murine model.

Biochem Biophys Rep 2016 Mar 19;5:482-491. Epub 2016 Feb 19.

Division of Cancer Immunotherapy, Exploratory Oncology Research & Clinical Trial Center National Cancer Center, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1016/j.bbrep.2016.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600353PMC
March 2016

A novel method for evaluating antibody-dependent cell-mediated cytotoxicity by flowcytometry using cryopreserved human peripheral blood mononuclear cells.

Sci Rep 2016 Jan 27;6:19772. Epub 2016 Jan 27.

Department of Clinical Pharmacology, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.1038/srep19772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728441PMC
January 2016

Tremelimumab-associated tumor regression following after initial progression: two case reports.

Immunotherapy 2016 2;8(1):9-15. Epub 2015 Oct 2.

Department of Experimental Therapeutics, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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https://www.futuremedicine.com/doi/10.2217/imt.15.89
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http://dx.doi.org/10.2217/imt.15.89DOI Listing
June 2016

Tremelimumab-associated tumor regression following after initial progression: two case reports.

Immunotherapy 2016 2;8(1):9-15. Epub 2015 Oct 2.

Department of Experimental Therapeutics, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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https://www.futuremedicine.com/doi/10.2217/imt.15.89
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http://dx.doi.org/10.2217/imt.15.89DOI Listing
June 2016

Clinical Development of Immune Checkpoint Inhibitors.

Biomed Res Int 2015 16;2015:605478. Epub 2015 Jun 16.

Department of Experimental Therapeutics, Exploratory Oncology Research and Clinical Trial Center (EPOC), National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan ; Division of Cancer Immunotherapy, Exploratory Oncology Research and Clinical Trial Center (EPOC), National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.1155/2015/605478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486755PMC
February 2016

Clinical Development of Immune Checkpoint Inhibitors.

Biomed Res Int 2015 16;2015:605478. Epub 2015 Jun 16.

Department of Experimental Therapeutics, Exploratory Oncology Research and Clinical Trial Center (EPOC), National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan ; Division of Cancer Immunotherapy, Exploratory Oncology Research and Clinical Trial Center (EPOC), National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.1155/2015/605478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486755PMC
February 2016

Computational algorithm-driven evaluation of monocytic myeloid-derived suppressor cell frequency for prediction of clinical outcomes.

Cancer Immunol Res 2014 Aug 20;2(8):812-21. Epub 2014 May 20.

Memorial Sloan-Kettering Cancer Center; Weill-Cornell Medical and Graduate Schools; and Ludwig Collaborative and Swim Across America Lab, New York, New York

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http://dx.doi.org/10.1158/2326-6066.CIR-14-0013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125466PMC
August 2014

Enhancement of tumor-reactive cytotoxic CD4+ T cell responses after ipilimumab treatment in four advanced melanoma patients.

Cancer Immunol Res 2013 Oct;1(4):235-44

Ludwig Center for Cancer Immunotherapy, Immunology Program, Sloan-Kettering Cancer Center, New York, NY 10065 ; Department of Medicine, Sloan-Kettering Cancer Center, New York, NY 10065 ; Swim Across America Laboratory and Ludwig Institute for Cancer Research, Memorial, Sloan-Kettering Cancer Center, New York, NY 10065 ; Weill Cornell Medical College of Cornell University, New York, NY 10065.

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http://dx.doi.org/10.1158/2326-6066.CIR-13-0068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880021PMC
October 2013

Markers for anti-cytotoxic T-lymphocyte antigen 4 (CTLA-4) therapy in melanoma.

Methods Mol Biol 2014 ;1102:83-95

Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-62703-727-3_6DOI Listing
June 2014

Granzyme B is a novel interleukin-18 converting enzyme.

J Dermatol Sci 2010 Aug 17;59(2):129-35. Epub 2010 Jun 17.

Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie 514-8507, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2010.05.004DOI Listing
August 2010

Deletion of chromosome arm 15q in a case of minimally differentiated hypoplastic AML-M0.

Cancer Genet Cytogenet 2008 Jul;184(1):57-61

Department of Hematology and Oncology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507 Japan.

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http://dx.doi.org/10.1016/j.cancergencyto.2008.03.010DOI Listing
July 2008

Humoral immune responses in patients vaccinated with 1-146 HER2 protein complexed with cholesteryl pullulan nanogel.

Cancer Sci 2008 Mar 15;99(3):601-7. Epub 2007 Dec 15.

Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2007.00705.xDOI Listing
March 2008

Generation of peptide-specific CD8+ T cells by phytohemagglutinin-stimulated antigen-mRNA-transduced CD4+ T cells.

J Immunol Methods 2006 Jul 19;314(1-2):54-66. Epub 2006 Jun 19.

Second Department of Internal Medicine, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan.

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http://dx.doi.org/10.1016/j.jim.2006.05.009DOI Listing
July 2006