Publications by authors named "Shigehira Saji"

100Publications

Trend in Cancer incidence and mortality in Fukushima between 2008 and 2015.

J Epidemiol 2020 Sep 19. Epub 2020 Sep 19.

Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University.

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http://dx.doi.org/10.2188/jea.JE20200202DOI Listing
September 2020

The Japanese Breast Cancer Society clinical practice guidelines for surgical treatment of breast cancer, 2018 edition.

Breast Cancer 2020 Jan 12;27(1):4-8. Epub 2019 Dec 12.

Department of Breast Oncology, Aichi Cancer Center Hospital, Nagoya, Aichi, Japan.

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http://dx.doi.org/10.1007/s12282-019-01030-wDOI Listing
January 2020

Characteristics of adverse events of endocrine therapies among older patients with breast cancer.

Support Care Cancer 2019 Oct 7;27(10):3813-3822. Epub 2019 Feb 7.

Breast Oncology Center, Cancer Institute Hospital, Ariake 3-8-31, Koto-ku, Tokyo, 135-8550, Japan.

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http://dx.doi.org/10.1007/s00520-019-04674-8DOI Listing
October 2019

Estradiol promotes rapid degradation of HER3 in ER-positive breast cancer cell line MCF-7.

Biochem Biophys Rep 2018 Dec 26;16:103-109. Epub 2018 Oct 26.

Department of Medical Oncology, Fukushima Medical University, 1 Hikariga-oka, Fukushima-shi, Fukushima 960-1295, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S24055808183013
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http://dx.doi.org/10.1016/j.bbrep.2018.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205365PMC
December 2018

Poland syndrome accompanied by internal iliac artery supply disruption sequence: a case report.

J Med Case Rep 2018 Oct 26;12(1):312. Epub 2018 Oct 26.

Department of Gastrointestinal Tract Surgery, Fukushima Medical University, 1 Hikarigaoka, Fukushima City, Fukushima, 960-1295, Japan.

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https://jmedicalcasereports.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13256-018-1823-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203193PMC
October 2018

Long isoform of VEGF stimulates cell migration of breast cancer by filopodia formation via NRP1/ARHGAP17/Cdc42 regulatory network.

Int J Cancer 2018 12 9;143(11):2905-2918. Epub 2018 Oct 9.

Department of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1002/ijc.31645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282968PMC
December 2018

The long and winding road for overcoming resistance to hormone therapy in breast cancer.

Authors:
Shigehira Saji

Breast Cancer 2018 Jul;25(4):377-378

Department of Medical Oncology, School of Medicine, Fukushima Medical University, 1 Hikarigaoka, Fukushima City, Fukushima, 960-1295, Japan.

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http://link.springer.com/10.1007/s12282-018-0876-2
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http://dx.doi.org/10.1007/s12282-018-0876-2DOI Listing
July 2018

The relationship between serum E2 levels and recurrence in premenopausal, ER-positive breast cancer patients: A retrospective study.

Breast Dis 2018 ;37(4):185-190

Department of Breast Surgery, The Tazuke Kofukai Medical Research Institute Kitano Hospital, 2-4-20 Ogi-machi Kita-ku Osaka, 530-8480 Japan.

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http://dx.doi.org/10.3233/BD-170307DOI Listing
April 2019

Impact of physiological hormonal fluctuations on F-fluorodeoxyglucose uptake in breast cancer.

Breast Cancer Res Treat 2018 Jun 8;169(3):437-446. Epub 2018 Feb 8.

Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Hospital, 54 Shogoin-Kawaharacho, Sakyo-ku, Kyoto City, Kyoto, 606-8507, Japan.

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http://link.springer.com/10.1007/s10549-018-4711-4
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http://dx.doi.org/10.1007/s10549-018-4711-4DOI Listing
June 2018

[III. Novel Endocrine Therapy with Signal Transduction Inhibitors for Hormone Dependent Breast Cancer].

Gan To Kagaku Ryoho 2016 Dec;43(13):2509-2512

Dept. of Breast Surgery, Fukushima Medical University School of Medicine.

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December 2016

Estrogen-Related Factors in the Frontal Lobe of Alzheimer's Disease Patients and Importance of Body Mass Index.

Sci Rep 2017 04 7;7(1):726. Epub 2017 Apr 7.

Department of Biochemistry, Fujita Health University School of Medicine, Dengakugakubo 1-98, Kutsukake-cho, Toyoake, 470-1192, Japan.

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http://dx.doi.org/10.1038/s41598-017-00815-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429714PMC
April 2017

Circulating cell-free DNA-based epigenetic assay can detect early breast cancer.

Breast Cancer Res 2016 12 19;18(1):129. Epub 2016 Dec 19.

Department of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1186/s13058-016-0788-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168705PMC
December 2016

Social isolation and cancer management after the 2011 triple disaster in Fukushima, Japan: A case report of breast cancer with patient and provider delay.

Medicine (Baltimore) 2016 Jun;95(26):e4027

aDepartment of Surgery bDepartment of Research cDepartment of Radiation Protection, Minamisoma Municipal General Hospital, Minamisoma, Fukushima dDepartment of Internal Medicine, Jyoban Hospital of Tokiwakai Group, Iwaki eDepartment of Medical Oncology, Fukushima Medical University fResearch Institute of Innovative Medicine, Jyoban Hospital, Iwaki, Fukushima gMedical Governance Research Institute, Minato-ku, Tokyo, Japan.

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http://dx.doi.org/10.1097/MD.0000000000004027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937939PMC
June 2016

[Combination Therapy of Molecular-Targeted Drugs for Breast Cancer -- Their Potential in the Future].

Gan To Kagaku Ryoho 2016 Apr;43(4):398-403

Dept. of Organ Regulatory Surgery, Fukushima Medical University, School of Medicine.

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April 2016

Molecular diagnostics for precision medicine in breast cancer treatment: what does the future hold?

Breast Cancer 2016 Jan;23(1):1-3

Department of Medical Oncology, Fukushima Medical University, School of Medicine, 1 Hikarigaoka, Fukushima, Fukushima, 960-1295, Japan.

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http://dx.doi.org/10.1007/s12282-015-0657-0DOI Listing
January 2016

Palbociclib in Hormone-Receptor-Positive Advanced Breast Cancer.

N Engl J Med 2015 10;373(17):1672-3

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http://dx.doi.org/10.1056/NEJMc1510345DOI Listing
October 2015

Differences in clinical importance of Bcl-2 in breast cancer according to hormone receptors status or adjuvant endocrine therapy.

BMC Cancer 2015 Oct 15;15:698. Epub 2015 Oct 15.

Department of Pathology, Cancer Institute, 3-8-31 Ariake, Koto-ku, Tokyo, 135-8550, Japan.

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http://dx.doi.org/10.1186/s12885-015-1686-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607008PMC
October 2015

Joint symptoms and health-related quality of life in postmenopausal women with breast cancer who completed 5 years of anastrozole.

Support Care Cancer 2016 Feb 8;24(2):683-689. Epub 2015 Jul 8.

Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, 1-1-1, Noji-Higashi, Kusatsu, 525-8577, Japan.

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http://link.springer.com/content/pdf/10.1007%2Fs00520-015-28
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http://link.springer.com/10.1007/s00520-015-2830-6
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http://dx.doi.org/10.1007/s00520-015-2830-6DOI Listing
February 2016

Genomic tumor evolution of breast cancer.

Breast Cancer 2016 Jan 22;23(1):4-11. Epub 2015 May 22.

Department of Breast Surgery, Graduate School of Medicine, Kyoto University, 54 Kawaracho, Shogoin, Sakyokun, Kyoto, Kyoto, 606-8507, Japan.

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http://dx.doi.org/10.1007/s12282-015-0617-8DOI Listing
January 2016

[Leanness, obesity, and breast cancer risk-different impact of body weight on breast cancer risk according to women's life stages].

Gan To Kagaku Ryoho 2015 May;42(5):525-8

Unit for Medical Nutrition, Dept. of Healthcare, Tokyo Healthcare University.

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May 2015

[Mechanism and side effect of endocrine therapy].

Nihon Rinsho 2015 Feb;73 Suppl 2:291-7

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February 2015

Combination of molecular-targeted drugs with endocrine therapy for hormone-resistant breast cancer.

Int J Clin Oncol 2015 Apr 24;20(2):268-72. Epub 2015 Feb 24.

Department of Medical Oncology, Fukushima Medical University, School of Medicine, 1 Hikarigaoka, Fukushima, Fukushima, 960-1295, Japan,

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http://dx.doi.org/10.1007/s10147-015-0799-2DOI Listing
April 2015

Brain metastases in breast cancer.

Jpn J Clin Oncol 2014 Dec 15;44(12):1133-40. Epub 2014 Oct 15.

Department of Breast Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.

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http://dx.doi.org/10.1093/jjco/hyu156DOI Listing
December 2014

Proportion of estrogen or progesterone receptor expressing cells in breast cancers and response to endocrine therapy.

Breast 2014 Dec 29;23(6):754-62. Epub 2014 Aug 29.

Department of Pathology, Cancer Institute, 3-8-31 Ariake, Koto-ku, Tokyo 135-8550, Japan.

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http://dx.doi.org/10.1016/j.breast.2014.08.003DOI Listing
December 2014

Association of positive EBAG9 immunoreactivity with unfavorable prognosis in breast cancer patients treated with tamoxifen.

Clin Breast Cancer 2013 Dec 8;13(6):465-70. Epub 2013 Oct 8.

Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, Saitama, Japan.

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http://dx.doi.org/10.1016/j.clbc.2013.08.015DOI Listing
December 2013

Potential clinical applications of matrix metalloproteinase inhibitors and their future prospects.

Int J Biol Markers 2013 Jun 28;28(2):117-30. Epub 2013 Jun 28.

Department of Breast Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.5301/jbm.5000026DOI Listing
June 2013

Evolving approaches to metastatic breast cancer patients pre-treated with anthracycline and taxane.

Authors:
Shigehira Saji

BioDrugs 2013 Oct;27(5):469-78

Department of Target Therapy Oncology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan,

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http://dx.doi.org/10.1007/s40259-013-0038-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775160PMC
October 2013

Impact of recent parity on histopathological tumor features and breast cancer outcome in premenopausal Japanese women.

Breast Cancer Res Treat 2013 Apr 4;138(3):941-50. Epub 2013 Apr 4.

Division of Breast and Medical Oncology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.1007/s10549-013-2507-0DOI Listing
April 2013

[Clinical pharmacology of targeted drug for breast cancer].

Nihon Rinsho 2012 Nov;70 Suppl 8:443-6

Outpatient Oncology Unit, Kyoto University Hospital.

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November 2012

[Molecular targeting agent to steroid hormone synthesis; aromatase inhibitor].

Authors:
Shigehira Saji

Nihon Rinsho 2012 Nov;70 Suppl 8:103-8

Department of Target Therapy Oncology, Kyoto University Graduate School of Medicine.

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November 2012

Ki-67 evaluation at the hottest spot predicts clinical outcome of patients with hormone receptor-positive/HER2-negative breast cancer treated with adjuvant tamoxifen monotherapy.

Breast Cancer 2015 Jan 12;22(1):71-8. Epub 2013 Mar 12.

Research Team for Geriatric Pathology, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakaecho, Itabashi-ku, Tokyo, 173-0015, Japan,

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http://dx.doi.org/10.1007/s12282-013-0455-5DOI Listing
January 2015

Impact of body mass index on breast cancer in accordance with the life-stage of women.

Front Oncol 2012 4;2:123. Epub 2012 Oct 4.

Division of Medical Nutrition, Department of Healthcare, Tokyo Health Care University Tokyo, Japan.

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http://dx.doi.org/10.3389/fonc.2012.00123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463802PMC
October 2012

Expression of DBC1 is associated with nuclear grade and HER2 expression in breast cancer.

Exp Ther Med 2011 Nov 12;2(6):1105-1109. Epub 2011 Aug 12.

Departments of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-8655;

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http://dx.doi.org/10.3892/etm.2011.333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440794PMC
November 2011

Concomitant polypharmacy is associated with irinotecan-related adverse drug reactions in patients with cancer.

Int J Clin Oncol 2013 Aug 26;18(4):735-42. Epub 2012 May 26.

Department of Clinical Research Support Center, International Medical Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan.

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http://dx.doi.org/10.1007/s10147-012-0425-5DOI Listing
August 2013

Association of double-positive FOXA1 and FOXP1 immunoreactivities with favorable prognosis of tamoxifen-treated breast cancer patients.

Horm Cancer 2012 Aug 3;3(4):147-59. Epub 2012 Apr 3.

Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, Saitama, Japan.

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http://dx.doi.org/10.1007/s12672-012-0111-0DOI Listing
August 2012

Clinical importance of androgen receptor in breast cancer patients treated with adjuvant tamoxifen monotherapy.

Breast Cancer 2012 Feb 4. Epub 2012 Feb 4.

Research Team for Geriatric Pathology, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakaecho, Itabashi-ku, Tokyo, 173-0015, Japan,

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http://dx.doi.org/10.1007/s12282-012-0337-2DOI Listing
February 2012

Association of ABCC2 genotype with efficacy of first-line FOLFIRI in Japanese patients with advanced colorectal cancer.

Drug Metab Pharmacokinet 2012 27;27(3):325-35. Epub 2011 Dec 27.

Department of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical University, Hidaka, Japan.

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http://dx.doi.org/10.2133/dmpk.dmpk-11-rg-128DOI Listing
January 2013

Trends in local therapy application for early breast cancer patients in the Japanese Breast Cancer Society Breast Cancer Registry during 2004-2009.

Breast Cancer 2012 Jan;19(1):1-3

Department of Target Therapy Oncology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1007/s12282-011-0308-zDOI Listing
January 2012

[Predictors of axillary node metastasis at breast surgery after neoadjuvant chemotherapy in patients with pre- chemotherapy-sentinel node positive breast cancer].

Gan To Kagaku Ryoho 2011 Oct;38(10):1639-45

Department of Breast Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan.

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October 2011

Possible available treatment option for early stage, small, node-negative, and HER2-overexpressing breast cancer.

Breast Cancer 2012 Apr 24;19(2):95-103. Epub 2011 Aug 24.

Department of Medical Oncology, International Medical Center, Saitama Medical University, Hidaka, Japan.

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http://dx.doi.org/10.1007/s12282-011-0296-zDOI Listing
April 2012

Sex steroid hormones in pairs of tumor and serum from breast cancer patients and pathobiological role of androstene-3β, 17β-diol.

Cancer Sci 2011 Oct 10;102(10):1848-54. Epub 2011 Aug 10.

Research Team for Geriatric Pathology, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2011.02018.xDOI Listing
October 2011

Associations among baseline variables, treatment-related factors and health-related quality of life 2 years after breast cancer surgery.

Breast Cancer Res Treat 2011 Aug 17;128(3):735-47. Epub 2011 Jun 17.

Department of Breast and Endocrine Surgery, Okayama University Hospital, Okayama, Japan.

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http://dx.doi.org/10.1007/s10549-011-1631-yDOI Listing
August 2011

Regimen selection for first-line FOLFIRI and FOLFOX based on UGT1A1 genotype and physical background is feasible in Japanese patients with advanced colorectal cancer.

Jpn J Clin Oncol 2011 May 9;41(5):617-23. Epub 2011 Feb 9.

Department of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama 350-1298, Japan.

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http://dx.doi.org/10.1093/jjco/hyr010DOI Listing
May 2011

Delayed elimination of SN-38 in cancer patients with severe renal failure.

Drug Metab Dispos 2011 Feb 27;39(2):161-4. Epub 2010 Oct 27.

Department of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan.

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http://dx.doi.org/10.1124/dmd.110.035451DOI Listing
February 2011

Refractory lung metastasis from breast cancer treated with multidisciplinary therapy including an immunological approach.

Breast Cancer 2011 Jan 31;18(1):64-7. Epub 2010 Mar 31.

Department of Breast Surgery, Graduate School of Medicine, Kyoto University, 54 Kawaracho, Shogoin, Sakyo-ku, Kyoto, Japan.

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http://dx.doi.org/10.1007/s12282-010-0198-5DOI Listing
January 2011

Effect of low-dose Paclitaxel and docetaxel on endothelial progenitor cells.

Oncology 2009 3;77(3-4):182-91. Epub 2009 Sep 3.

Department of Health and Dietetics, Faculty of Medical Health, Teikyo Heisei University, Tokyo, Japan.

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http://dx.doi.org/10.1159/000236016DOI Listing
October 2009