Dr. Shigeharu Wakana, PhD - RIKEN BioResource Center - Team Leader

Dr. Shigeharu Wakana

PhD

RIKEN BioResource Center

Team Leader

Tsukuba, Ibaraki | Japan

Dr. Shigeharu Wakana, PhD - RIKEN BioResource Center - Team Leader

Dr. Shigeharu Wakana

PhD

Introduction

Primary Affiliation: RIKEN BioResource Center - Tsukuba, Ibaraki , Japan

Publications

81Publications

2194Reads

83Profile Views

777PubMed Central Citations

Paternal Aging Affects Behavior in Pax6 Mutant Mice: A Gene/Environment Interaction in Understanding Neurodevelopmental Disorders.

PLoS One 2016 17;11(11):e0166665. Epub 2016 Nov 17.

Department of Developmental Neuroscience, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0166665PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113965PMC
June 2017
37 Reads
2 Citations
3.234 Impact Factor

A spontaneous and novel Pax3 mutant mouse that models Waardenburg syndrome and neural tube defects.

Gene 2017 Apr 30;607:16-22. Epub 2016 Dec 30.

Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Wako, Saitama, Japan.

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http://dx.doi.org/10.1016/j.gene.2016.12.037DOI Listing
April 2017
12 Reads
1 Citation
2.140 Impact Factor

Microphthalmia-associated transcription factor ensures the elongation of axons and dendrites in the mouse frontal cortex.

Genes Cells 2016 Dec 11;21(12):1365-1379. Epub 2016 Nov 11.

Department of Molecular Biology and Applied Physiology, Tohoku University School of Medicine, Sendai, Miyagi, 980-8575, Japan.

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http://dx.doi.org/10.1111/gtc.12450DOI Listing
December 2016
9 Reads
2.810 Impact Factor

Mouse D1Pas1, a DEAD-box RNA helicase, is required for the completion of first meiotic prophase in male germ cells.

Biochem Biophys Res Commun 2016 09 27;478(2):592-8. Epub 2016 Jul 27.

RIKEN BioResource Center, Tsukuba, Ibaraki, 305-0074, Japan; Graduate School of Life and Environmental Science, University of Tsukuba, Ibaraki, 305-8572, Japan; The Center for Disease Biology and Integrative Medicine, Faculty of Medicine, University of Tokyo, Tokyo, 113-0033, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.07.109DOI Listing
September 2016
39 Reads
2.300 Impact Factor

ATF7 ablation prevents diet-induced obesity and insulin resistance.

Biochem Biophys Res Commun 2016 09 3;478(2):696-702. Epub 2016 Aug 3.

Laboratory of Molecular Genetics, RIKEN Tsukuba Institute, 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074, Japan; Department of Molecular Genetics and Ph.D. Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.08.009DOI Listing
September 2016
19 Reads
2 Citations
2.300 Impact Factor

High-throughput discovery of novel developmental phenotypes.

Nature 2016 09 14;537(7621):508-514. Epub 2016 Sep 14.

The Jackson Laboratory, Bar Harbor, Maine 04609, USA.

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http://dx.doi.org/10.1038/nature19356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295821PMC
September 2016
85 Reads
79 Citations
42.351 Impact Factor

Novel allelic mutations in murine Serca2 induce differential development of squamous cell tumors.

Biochem Biophys Res Commun 2016 08 27;476(4):175-182. Epub 2016 Apr 27.

Team for Advanced Development and Evaluation of Human Disease Models, Riken BioResource Center (BRC), Tsukuba, Ibaraki, Japan; Department of Cell Biology, Cancer Institute, The Japanese Foundation for Cancer Research, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.04.136DOI Listing
August 2016
15 Reads
2.300 Impact Factor

Severe ocular phenotypes in Rbp4-deficient mice in the C57BL/6 genetic background.

Lab Invest 2016 06 14;96(6):680-91. Epub 2016 Mar 14.

Department of Histology and Embryology, Harbin Medical University, Harbin, China.

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http://dx.doi.org/10.1038/labinvest.2016.39DOI Listing
June 2016
17 Reads
2 Citations
3.680 Impact Factor

Endoplasmic reticulum stress-mediated apoptosis contributes to a skeletal dysplasia resembling platyspondylic lethal skeletal dysplasia, Torrance type, in a novel Col2a1 mutant mouse line.

Biochem Biophys Res Commun 2015 Dec 4-11;468(1-2):86-91. Epub 2015 Nov 9.

Laboratory of Laboratory Animal Science and Medicine, Co-Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, 3-18-8 Ueda, Morioka, Iwate 020-8550, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.10.160DOI Listing
March 2016
4 Reads
2.300 Impact Factor

Low-cost three-dimensional gait analysis system for mice with an infrared depth sensor.

Neurosci Res 2015 Nov 10;100:55-62. Epub 2015 Jul 10.

Graduate School of Information Science, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara 630-0192, Japan; Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, Fukuoka, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.neures.2015.06.006DOI Listing
November 2015
20 Reads
1 Citation
1.940 Impact Factor

STAP cells are derived from ES cells.

Nature 2015 Sep;525(7570):E4-5

Cell Asymmetry, RIKEN Center for Developmental Biology, 2-2-3 Minatojima-Minamimachi, Chuo-ku, Kobe 650-0047, Japan.

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http://dx.doi.org/10.1038/nature15366DOI Listing
September 2015
57 Reads
42.351 Impact Factor

Germline mutation rates and the long-term phenotypic effects of mutation accumulation in wild-type laboratory mice and mutator mice.

Genome Res 2015 Aug 30;25(8):1125-34. Epub 2015 Jun 30.

KOKORO-Biology Group, Laboratories for Integrated Biology, Graduate School of Frontier Biosciences, Osaka University, Suita 565-0871, Japan;

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http://dx.doi.org/10.1101/gr.186148.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509997PMC
August 2015
12 Reads
24 Citations
14.630 Impact Factor

KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR.

Nat Commun 2015 Jun 17;6:7474. Epub 2015 Jun 17.

1] Division of Molecular Neuroimmunology, Institute for Genetic Medicine and Graduate School of Medicine, Hokkaido University, Kita-15, Nishi-7, Kita-ku, Sapporo 060-0815, Japan [2] Laboratory of Developmental Immunology, Graduate School of Frontier Biosciences, Graduate School of Medicine, and WPI Immunology Frontier Research Center, Osaka University, 2-2, Yamada-oka, Suita 565-0871, Japan.

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http://dx.doi.org/10.1038/ncomms8474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557295PMC
June 2015
63 Reads
8 Citations
10.742 Impact Factor

A Cascade of epistatic interactions regulating teratozoospermia in mice.

Mamm Genome 2015 Jun 12;26(5-6):248-56. Epub 2015 May 12.

Animal Genome Research Unit, Agrogenomics Research Center, National Institute of Agrobiological Sciences, 1-2 Owashi, Tsukuba, Ibaraki, 305-8634, Japan.

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http://dx.doi.org/10.1007/s00335-015-9566-yDOI Listing
June 2015
23 Reads
1 Citation
3.070 Impact Factor

Polygenic expression of teratozoospermia and normal fertility in B10.MOL-TEN1 mouse strain.

Congenit Anom (Kyoto) 2015 May;55(2):92-8

Animal Genome Research Unit, Agrogenomics Research Center, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki, Japan; Graduate School of Science and Engineering, Yamagata University, Yamagata, Japan.

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http://dx.doi.org/10.1111/cga.12102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680107PMC
May 2015
13 Reads
1 Citation
0.783 Impact Factor

IRBIT regulates CaMKIIα activity and contributes to catecholamine homeostasis through tyrosine hydroxylase phosphorylation.

Proc Natl Acad Sci U S A 2015 Apr 14;112(17):5515-20. Epub 2015 Apr 14.

Laboratory for Developmental Neurobiology, Brain Science Institute, RIKEN, Wako, Saitama 351-0198, Japan;

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http://dx.doi.org/10.1073/pnas.1503310112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418850PMC
April 2015
13 Reads
9 Citations
9.810 Impact Factor

Lack of stress responses to long-term effects of corticosterone in Caps2 knockout mice.

Sci Rep 2015 Mar 10;5:8932. Epub 2015 Mar 10.

1] Laboratory for Molecular Neurogenesis, RIKEN Brain Science Institute, Wako, Saitama, Japan [2] CREST, Kawaguchi, Saitama, Japan [3] Faculty of Science and Technology, Tokyo University of Science, Noda, Chiba, Japan.

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http://dx.doi.org/10.1038/srep08932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354153PMC
March 2015
19 Reads
2 Citations
5.080 Impact Factor

Congenic mapping and allele-specific alteration analysis of Stmm1 locus conferring resistance to early-stage chemically induced skin papillomas.

PLoS One 2014 20;9(5):e97201. Epub 2014 May 20.

Department of Carcinogenesis Research, Division of Experimental Animal Research, Chiba Cancer Center Research Institute, Chiba, Chiba, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097201PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028187PMC
February 2015
41 Reads
2 Citations
3.234 Impact Factor

Identification of Stmm3 locus conferring resistance to late-stage chemically induced skin papillomas on mouse chromosome 4 by congenic mapping and allele-specific alteration analysis.

Exp Anim 2014 ;63(3):339-48

Department of Carcinogenesis Research, Division of Experimental Animal Research, Chiba Cancer Center Research Institute, 666-2 Nitonacho, Chuouku, Chiba 260-8717, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206738PMC
http://dx.doi.org/10.1538/expanim.63.339DOI Listing
February 2015
27 Reads
3 Citations

Effects of background mutations and single nucleotide polymorphisms (SNPs) on the Disc1 L100P behavioral phenotype associated with schizophrenia in mice.

Behav Brain Funct 2014 Dec 8;10:45. Epub 2014 Dec 8.

Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University School of Medicine, 800 Kitakobayashi, Mibu-machi, Shimotsuga-gun, Tochigi 321-0293, Japan.

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http://dx.doi.org/10.1186/1744-9081-10-45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295473PMC
December 2014
27 Reads
5 Citations
1.972 Impact Factor

Sirh7/Ldoc1 knockout mice exhibit placental P4 overproduction and delayed parturition.

Development 2014 Dec;141(24):4763-71

School of Health Sciences, Tokai University, Bohseidai, Isehara, Kanagawa 259-1193, Japan

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http://dx.doi.org/10.1242/dev.114520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299276PMC
December 2014
19 Reads
10 Citations
6.462 Impact Factor

Novel retinoblastoma mutation abrogating the interaction to E2F2/3, but not E2F1, led to selective suppression of thyroid tumors.

Cancer Sci 2014 Oct 29;105(10):1360-8. Epub 2014 Sep 29.

Team for Advanced Development and Evaluation of Human Disease Models, Riken BioResource Center, Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1111/cas.12495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462357PMC
October 2014
30 Reads
1 Citation

Pheno-Pub: a total support system for the publication of mouse phenotypic data on the web.

Mamm Genome 2013 Dec 13;24(11-12):473-83. Epub 2013 Nov 13.

Technology and Development Team for Mouse Phenotype Analysis, RIKEN BioResource Center, 3-1-1 Koyadai, Tsukuba, Ibaraki, 305-0074, Japan,

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http://dx.doi.org/10.1007/s00335-013-9482-yDOI Listing
December 2013
2 Reads
2 Citations
3.070 Impact Factor

Significance of glycosylphosphatidylinositol-anchored protein enrichment in lipid rafts for the control of autoimmunity.

J Biol Chem 2013 Aug 17;288(35):25490-9. Epub 2013 Jul 17.

Department of Immunoregulation, Research Institute for Microbial Diseases, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan.

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http://dx.doi.org/10.1074/jbc.M113.492611DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757210PMC
August 2013
20 Reads
5 Citations
4.573 Impact Factor

Novel mouse model for Gardner syndrome generated by a large-scale N-ethyl-N-nitrosourea mutagenesis program.

Cancer Sci 2013 Jul 18;104(7):937-44. Epub 2013 May 18.

Team for Advanced Development and Evaluation of Human Disease Models, Riken BioResource Center, Tsukuba, Japan.

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http://dx.doi.org/10.1111/cas.12161DOI Listing
July 2013
27 Reads
3 Citations

ENU-mutagenesis mice with a non-synonymous mutation in Grin1 exhibit abnormal anxiety-like behaviors, impaired fear memory, and decreased acoustic startle response.

BMC Res Notes 2013 May 21;6:203. Epub 2013 May 21.

Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, 1-98 Dengakugakubo Kutsukake-cho, Toyoake 470-1192, Japan.

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http://link.springer.com/content/pdf/10.1186%2F1756-0500-6-2
Web Search
http://bmcresnotes.biomedcentral.com/articles/10.1186/1756-0
Publisher Site
http://dx.doi.org/10.1186/1756-0500-6-203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674941PMC
May 2013
27 Reads
8 Citations

Independent genetic control of early and late stages of chemically induced skin tumors in a cross of a Japanese wild-derived inbred mouse strain, MSM/Ms.

Carcinogenesis 2012 Nov 28;33(11):2260-8. Epub 2012 Jul 28.

Department of Carcinogenesis Research, Division of Experimental Animal Research, Chiba Cancer Center Research Institute, 666-2 Nitonacho Chuouku, Chiba 260-8717, Japan.

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http://dx.doi.org/10.1093/carcin/bgs250DOI Listing
November 2012
39 Reads
7 Citations
5.334 Impact Factor

QTL on mouse chromosomes 1 and 4 causing sperm-head morphological abnormality and male subfertility.

Mamm Genome 2012 Aug 22;23(7-8):399-403. Epub 2012 Mar 22.

Agrogenomics Research Center, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1007/s00335-012-9395-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401295PMC
August 2012
19 Reads
1 Citation
3.070 Impact Factor

Behavioral and neuromorphological characterization of a novel Tuba1 mutant mouse.

Behav Brain Res 2012 Feb 11;227(1):167-74. Epub 2011 Nov 11.

Technology and Development Team for Mouse Phenotype Analysis, Japan Mouse Clinic, RIKEN Bioresource Center, 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074, Japan.

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http://dx.doi.org/10.1016/j.bbr.2011.11.002DOI Listing
February 2012
2 Reads
4 Citations
3.030 Impact Factor

Comprehensive behavioral analysis of ENU-induced Disc1-Q31L and -L100P mutant mice.

BMC Res Notes 2012 Feb 20;5:108. Epub 2012 Feb 20.

Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, Japan.

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http://dx.doi.org/10.1186/1756-0500-5-108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392730PMC
February 2012
38 Reads
19 Citations

Intracytoplasmic sperm injection induces transcriptome perturbation without any transgenerational effect.

Biochem Biophys Res Commun 2011 Jul 30;410(2):282-8. Epub 2011 May 30.

Department of Epigenetics, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2011.05.133DOI Listing
July 2011
33 Reads
8 Citations
2.300 Impact Factor

ENU-induced missense mutation in the C-propeptide coding region of Col2a1 creates a mouse model of platyspondylic lethal skeletal dysplasia, Torrance type.

Mamm Genome 2011 Jun 3;22(5-6):318-28. Epub 2011 May 3.

Laboratory Animal Facility, Research Center for Medical Sciences, Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo 105-8461, Japan.

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http://link.springer.com/content/pdf/10.1007/s00335-011-9329
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http://link.springer.com/10.1007/s00335-011-9329-3
Publisher Site
http://dx.doi.org/10.1007/s00335-011-9329-3DOI Listing
June 2011
93 Reads
4 Citations
3.070 Impact Factor

ENU mutagenesis screening for dominant behavioral mutations based on normal control data obtained in home-cage activity, open-field, and passive avoidance tests.

Exp Anim 2010 ;59(4):495-510

Technology and Development Team for Mouse Phenotype Analysis, Japan Mouse Clinic, RIKEN BioResource Center, Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1538/expanim.59.495DOI Listing
November 2010
26 Reads
3 Citations

Phenotypic characterization of a new Grin1 mutant mouse generated by ENU mutagenesis.

Eur J Neurosci 2010 Apr 19;31(7):1281-91. Epub 2010 Mar 19.

Technology and Development Team for Mouse Phenotype Analysis: Japan Mouse Clinic, RIKEN Bioresource Center, 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074, Japan.

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http://dx.doi.org/10.1111/j.1460-9568.2010.07164.xDOI Listing
April 2010
49 Reads
11 Citations
3.181 Impact Factor

SDOP-DB: a comparative standardized-protocol database for mouse phenotypic analyses.

Bioinformatics 2010 Apr 1;26(8):1133-4. Epub 2010 Mar 1.

Technology and Development Unit for Knowledge Base of Mouse Phenotype, RIKEN BioResource Center, Tsukuba 305-0074, Japan.

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http://dx.doi.org/10.1093/bioinformatics/btq095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853689PMC
April 2010
26 Reads
2 Citations
4.981 Impact Factor

xCT deficiency accelerates chemically induced tumorigenesis.

Proc Natl Acad Sci U S A 2010 Apr 22;107(14):6436-41. Epub 2010 Mar 22.

Laboratory for Innate Cellular Immunity and Laboratory for Immunogenetics, RIKEN Research Center for Allergy and Immunology, Tsurumi, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1073/pnas.0912827107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852021PMC
April 2010
6 Reads
12 Citations
9.810 Impact Factor

Establishment of an improved mouse model for infantile neuroaxonal dystrophy that shows early disease onset and bears a point mutation in Pla2g6.

Am J Pathol 2009 Dec 5;175(6):2257-63. Epub 2009 Nov 5.

Division of Bioregulation Research, Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki-City, Kanagawa, Japan.

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http://dx.doi.org/10.2353/ajpath.2009.090343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789634PMC
December 2009
23 Reads
20 Citations
4.591 Impact Factor

Introduction to the Japan Mouse Clinic at the RIKEN BioResource Center.

Exp Anim 2009 Oct;58(5):443-50

Technology and Development Team for Mouse Phenotype Analysis, RIKEN BioResource Center, Tsukuba City, Ibaraki, Japan.

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http://dx.doi.org/10.1538/expanim.58.443DOI Listing
October 2009
38 Reads
9 Citations

A novel gene essential for the development of single positive thymocytes.

Mol Cell Biol 2009 Sep 20;29(18):5128-35. Epub 2009 Jul 20.

Laboratory for Lymphocyte Development, RIKEN Research Center for Allergy and Immunology, RIKEN Yokohama Institute, Yokohama, Kanagawa, Japan.

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http://mcb.asm.org/content/29/18/5128.full.pdf
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http://mcb.asm.org/content/early/2009/07/20/MCB.00793-09.ful
Web Search
http://mcb.asm.org/cgi/doi/10.1128/MCB.00793-09
Publisher Site
http://dx.doi.org/10.1128/MCB.00793-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738282PMC
September 2009
2 Reads
25 Citations
4.780 Impact Factor

PosMed (Positional Medline): prioritizing genes with an artificial neural network comprising medical documents to accelerate positional cloning.

Nucleic Acids Res 2009 Jul 25;37(Web Server issue):W147-52. Epub 2009 May 25.

Bioinformatics And Systems Engineering division, RIKEN. 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1093/nar/gkp384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703941PMC
July 2009
21 Reads
20 Citations
9.112 Impact Factor

A practical novel method for ensuring stable capacitation of spermatozoa from cryopreserved C57BL/6J sperm suspension.

Exp Anim 2009 Jul;58(4):395-401

Technology and Development Team for Mouse Phenotype Analysis, RIKEN BioResource Center, Koyadai, Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1538/expanim.58.395DOI Listing
July 2009
15 Reads
4 Citations

Identification and characterization of new long conserved noncoding sequences in vertebrates.

Mamm Genome 2008 Oct-Dec;19(10-12):703-12. Epub 2008 Nov 18.

RIKEN Genomic Sciences Center, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1007/s00335-008-9152-7DOI Listing
March 2009
4 Reads
14 Citations
3.070 Impact Factor

Objective evaluation measures of genetic marker selection in large-scale SNP genotyping.

J Bioinform Comput Biol 2008 Oct;6(5):905-17

Bioinformatics and Systems Engineering Division, RIKEN Yokohama Institute, 1-7-22, Suehiro, Tsurumi, Yokohama 230-0045, Japan.

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http://dx.doi.org/10.1142/s021972000800376xDOI Listing
October 2008
24 Reads
0.931 Impact Factor

Phenosite: a web database integrating the mouse phenotyping platform and the experimental procedures in mice.

J Bioinform Comput Biol 2007 Dec;5(6):1173-91

Mouse Functional Genomics Research Group, RIKEN GSC, Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1142/s0219720007003168DOI Listing
December 2007
4 Reads
6 Citations
0.931 Impact Factor

Mutations in the helix termination motif of mouse type I IRS keratin genes impair the assembly of keratin intermediate filament.

Genomics 2007 Dec 24;90(6):703-11. Epub 2007 Oct 24.

Mammalian Genetics Laboratory, Genetic Strains Research Center, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka, Japan.

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http://dx.doi.org/10.1016/j.ygeno.2007.07.013DOI Listing
December 2007
18 Reads
8 Citations
2.284 Impact Factor

An optimal embryo transfer condition for the effective production of DBA/2J mice.

Exp Anim 2007 Oct;56(5):385-8

Functional Genomics Research Group, RIKEN Genomic Sciences Center, Ibaraki, Japan.

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http://dx.doi.org/10.1538/expanim.56.385DOI Listing
October 2007
7 Reads
7 Citations

Implementation of the modified-SHIRPA protocol for screening of dominant phenotypes in a large-scale ENU mutagenesis program.

Mamm Genome 2005 Nov 11;16(11):829-37. Epub 2005 Nov 11.

Functional Genomics Research Group, RIKEN Genomic Sciences Center, 3-1-1 Kouyadai, Tsukubai, Ibaraki, Japan.

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http://dx.doi.org/10.1007/s00335-005-2430-8DOI Listing
November 2005
30 Reads
16 Citations
3.070 Impact Factor

Meg1/Grb10 overexpression causes postnatal growth retardation and insulin resistance via negative modulation of the IGF1R and IR cascades.

Biochem Biophys Res Commun 2005 Apr;329(3):909-16

Department of Epigenetics, Medical Research Institute, Tokyo Medical and Dental University, 2-3-10 Kandasurugadai, Chiyoda-ku, Tokyo 101-0062, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0500273
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http://dx.doi.org/10.1016/j.bbrc.2005.02.047DOI Listing
April 2005
11 Reads
20 Citations
2.300 Impact Factor

Deleted in polyposis 1-like 1 gene (Dp1l1): a novel gene richly expressed in retinal ganglion cells.

Invest Ophthalmol Vis Sci 2005 Mar;46(3):791-6

Department of Ophthalmology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan.

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http://dx.doi.org/10.1167/iovs.04-0867DOI Listing
March 2005
5 Citations
3.404 Impact Factor

Influence of H2 complex and non-H2 genes on progression of cutaneous lesions in mice infected with Leishmania amazonensis.

Parasitol Int 2004 Sep;53(3):217-21

Department of Molecular Immunology, School of Agriculture and Life Sciences, University of Tokyo 113-6857, Japan.

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http://dx.doi.org/10.1016/j.parint.2003.12.002DOI Listing
September 2004
2 Reads
2 Citations
2.111 Impact Factor

Differential geographic patterns of mitochondrial DNA variation in two sympatric species of Japanese wood mice, Apodemus speciosus and A. argenteus.

Genes Genet Syst 2004 Jun;79(3):165-76

Laboratory of Ecology and Genetics, Graduate School of Environmental Earth Science, Hokkaido University, Kita-ku, Sapporo, Japan.

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http://dx.doi.org/10.1266/ggs.79.165DOI Listing
June 2004
5 Reads
6 Citations
0.930 Impact Factor

The D5Mit7 locus on mouse chromosome 5 provides resistance to gamma-ray-induced but not N-methyl-N-nitrosourea-induced thymic lymphomas.

Carcinogenesis 2004 Jan 26;25(1):143-8. Epub 2003 Sep 26.

Department of Molecular Genetics, Graduate School of Medical and Dental Sciences, Niigata University, Japan.

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http://dx.doi.org/10.1093/carcin/bgg177DOI Listing
January 2004
5 Reads
5.334 Impact Factor

Phylogenetic conservation of a limb-specific, cis-acting regulator of Sonic hedgehog ( Shh).

Mamm Genome 2004 Jan;15(1):23-34

Mammalian Genetics Laboratory, National Institute of Genetics, Yata-1111, Mishima, Shizuoka-ken 411-8540, Japan.

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http://link.springer.com/content/pdf/10.1007%2Fs00335-033-23
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http://link.springer.com/10.1007/s00335-033-2317-5
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http://dx.doi.org/10.1007/s00335-033-2317-5DOI Listing
January 2004
11 Reads
37 Citations
3.070 Impact Factor

Mutations in a new scaffold protein Sans cause deafness in Jackson shaker mice.

Hum Mol Genet 2003 Mar;12(5):453-61

Department of Laboratory Animal Science, The Tokyo Metropolitan Institute of Medical Science (Rinshoken), Tokyo 113-8613, Japan.

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http://dx.doi.org/10.1093/hmg/ddg042DOI Listing
March 2003
17 Reads
40 Citations
6.393 Impact Factor

Mouse H2 haplotype influences on the survival rate after Angiostrongylus costaricensis infection.

Exp Parasitol 2002 Feb;100(2):140-2

Institute for Laboratory Animal Research, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.

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http://dx.doi.org/10.1016/S0014-4894(02)00006-1DOI Listing
February 2002
1 Read
1.860 Impact Factor

Top co-authors

Hiroshi Masuya
Hiroshi Masuya

Japan Mouse Clinic

29
Ikuo Miura
Ikuo Miura

St. Marianna University School of Medicine

29
Hideki Kaneda
Hideki Kaneda

Technology and Development Team for Mouse Phenotype Analysis

21
Tetsuo Noda
Tetsuo Noda

Graduate School of Medicine

21
Toshihiko Shiroishi
Toshihiko Shiroishi

National Institute of Genetics

19
Yoichi Gondo
Yoichi Gondo

Samuel Lunenfeld Research Institute

19
Tomohiro Suzuki
Tomohiro Suzuki

Research Institute of Green Science and Technology

17
Kimio Kobayashi
Kimio Kobayashi

RIKEN BioResource Center

15
Tamio Furuse
Tamio Furuse

National Institute of Genetics

14
Hiromi Motegi
Hiromi Motegi

Saitama Medical University

11