Publications by authors named "Sherry Niessen"

71Publications

Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling.

Cell Rep 2020 02;30(6):1935-1950.e8

Tumor Cell Biology, Pfizer Oncology Research & Development, La Jolla, Pfizer Inc., 10777 Science Center Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.celrep.2020.01.054DOI Listing
February 2020

Proteome-wide Map of Targets of T790M-EGFR-Directed Covalent Inhibitors.

Cell Chem Biol 2017 Nov 28;24(11):1388-1400.e7. Epub 2017 Sep 28.

Department of Molecular Medicine, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2017.08.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693604PMC
November 2017

Major Cys protease activities are not essential for senescence in individually darkened Arabidopsis leaves.

BMC Plant Biol 2017 01 6;17(1). Epub 2017 Jan 6.

The Plant Chemetics laboratory, Max Planck Institute for Plant Breeding Research, 50829, Cologne, Germany.

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http://dx.doi.org/10.1186/s12870-016-0955-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217659PMC
January 2017

Discovery of Enzymatic Targets of Transcriptional Activators via in Vivo Covalent Chemical Capture.

J Am Chem Soc 2016 09 20;138(38):12629-35. Epub 2016 Sep 20.

The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute , La Jolla, California 92037, United States.

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http://dx.doi.org/10.1021/jacs.6b07680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217703PMC
September 2016

Effects of Activating Mutations on EGFR Cellular Protein Turnover and Amino Acid Recycling Determined Using SILAC Mass Spectrometry.

Int J Cell Biol 2015 24;2015:798936. Epub 2015 Nov 24.

Worldwide Medicinal Chemistry, Pfizer, Inc., La Jolla Laboratories, 10770 Science Center Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1155/2015/798936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672139PMC
December 2015

Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors.

Mol Biol Cell 2015 May 25;26(10):1845-56. Epub 2015 Mar 25.

Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto 4150-180, Portugal Instituto de Investigação e Inovação em Saúde-i3S, Universidade do Porto, Porto 4150-180, Portugal

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http://dx.doi.org/10.1091/mbc.E14-11-1560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436830PMC
May 2015

A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors.

Nat Chem Biol 2014 Sep 13;10(9):760-767. Epub 2014 Jul 13.

The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, 10550 N. Torrey Pines Rd. La Jolla, CA, 92307.

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http://dx.doi.org/10.1038/nchembio.1582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138289PMC
September 2014

Chemoproteomic discovery of AADACL1 as a regulator of human platelet activation.

Chem Biol 2013 Sep 29;20(9):1125-34. Epub 2013 Aug 29.

Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2013.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948353PMC
September 2013

A chemical biology approach to interrogate quorum-sensing regulated behaviors at the molecular and cellular level.

Chem Biol 2013 Jul;20(7):903-11

The Skaggs Institute for Chemical Biology, Departments of Chemistry, Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.chembiol.2013.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736722PMC
July 2013

Direct binding of SAS-6 to ZYG-1 recruits SAS-6 to the mother centriole for cartwheel assembly.

Dev Cell 2013 May;25(3):284-98

Department of Cellular and Molecular Medicine, Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1016/j.devcel.2013.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655416PMC
May 2013

PRMT5 modulates the metabolic response to fasting signals.

Proc Natl Acad Sci U S A 2013 May 13;110(22):8870-5. Epub 2013 May 13.

The Clayton Foundation Laboratories for Peptide Biology, Salk Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.1304602110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670393PMC
May 2013

Hsp70/Hsp90 chaperone machinery is involved in the assembly of the purinosome.

Proc Natl Acad Sci U S A 2013 Feb 28;110(7):2528-33. Epub 2013 Jan 28.

Department of Chemistry, Pennsylvania State University, University Park, PA 16802, USA.

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http://dx.doi.org/10.1073/pnas.1300173110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574928PMC
February 2013

Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates.

Chem Biol 2012 May 26;19(5):579-88. Epub 2012 Apr 26.

The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.chembiol.2012.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361572PMC
May 2012

Single-step inline hydroxyapatite enrichment facilitates identification and quantitation of phosphopeptides from mass-limited proteomes with MudPIT.

J Proteome Res 2012 May 17;11(5):2697-709. Epub 2012 Apr 17.

Department of Chemical Physiology, The Scripps Research Institute, 10550 N. Torrey Pines Rd., La Jolla, California 92037, USA.

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http://dx.doi.org/10.1021/pr300200xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365658PMC
May 2012

Identification of a selective, activity-based probe for glyceraldehyde 3-phosphate dehydrogenases.

Angew Chem Int Ed Engl 2012 May 5;51(21):5230-3. Epub 2012 Apr 5.

Zentrum für Medizinische Biotechnologie, Fakultät für Biologie, Universität Duisburg-Essen, Universitätsstrasse 2, 45117 Essen, Germany.

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http://dx.doi.org/10.1002/anie.201107276DOI Listing
May 2012

Type I signal peptidase and protein secretion in Staphylococcus aureus.

J Bacteriol 2012 May 23;194(10):2677-86. Epub 2012 Mar 23.

Department of Chemistry, The Scripps Research Institute, La Jolla, California, USA.

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http://dx.doi.org/10.1128/JB.00064-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347181PMC
May 2012

Competitive activity-based protein profiling identifies aza-β-lactams as a versatile chemotype for serine hydrolase inhibition.

J Am Chem Soc 2012 Mar 8;134(11):5068-71. Epub 2012 Mar 8.

Department of Chemical Physiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.

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http://dx.doi.org/10.1021/ja300799tDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326416PMC
March 2012

Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics.

Plant Physiol 2012 Apr 27;158(4):1583-99. Epub 2012 Feb 27.

Plant Chemetics Laboratory, Chemical Genomics Centre of the Max Planck Society, Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany.

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http://dx.doi.org/10.1104/pp.112.194001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320171PMC
April 2012

The RON-receptor regulates pancreatic cancer cell migration through phosphorylation-dependent breakdown of the hemidesmosome.

Int J Cancer 2012 Oct 8;131(8):1744-54. Epub 2012 Mar 8.

Department of Surgery, Division of Surgical Oncology, Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1002/ijc.27447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424378PMC
October 2012

The zipcode-binding protein ZBP1 influences the subcellular location of the Ro 60-kDa autoantigen and the noncoding Y3 RNA.

RNA 2012 Jan 23;18(1):100-10. Epub 2011 Nov 23.

Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06536, USA.

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http://dx.doi.org/10.1261/rna.029207.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261732PMC
January 2012

Resin-based investigation of acyl carrier protein interaction networks in Escherichia coli.

Bioorg Med Chem 2012 Jan 31;20(2):667-71. Epub 2011 Oct 31.

Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0358, USA.

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http://dx.doi.org/10.1016/j.bmc.2011.10.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809020PMC
January 2012

Monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer.

Chem Biol 2011 Jul;18(7):846-56

The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.chembiol.2011.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149849PMC
July 2011

The proteome of mouse brain microvessel membranes and basal lamina.

J Cereb Blood Flow Metab 2011 Dec 27;31(12):2267-81. Epub 2011 Jul 27.

Department of Surgery, School of Medicine, University of California San Diego, San Diego, California 92103, USA.

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http://dx.doi.org/10.1038/jcbfm.2011.104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323187PMC
December 2011

Proteomic analysis of the coagulation reaction in plasma and whole blood using PROTOMAP.

Proteomics 2011 Jun 16;11(12):2377-88. Epub 2011 May 16.

Department of Chemical Physiology, The Center for Physiological Proteomics, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1002/pmic.201000674DOI Listing
June 2011

Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors.

Nat Chem Biol 2011 May 15;7(7):469-78. Epub 2011 May 15.

The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.

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http://dx.doi.org/10.1038/nchembio.579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118922PMC
May 2011

IGF1-R signals through the RON receptor to mediate pancreatic cancer cell migration.

Carcinogenesis 2011 Aug 11;32(8):1151-6. Epub 2011 May 11.

Department of Surgery, Division of Surgical Oncology, Moores Cancer Center, University of California, 3855 Health Sciences Drive, San Diego, CA 92093-0987, USA.

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https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
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http://dx.doi.org/10.1093/carcin/bgr086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149203PMC
August 2011

A hormone-dependent module regulating energy balance.

Cell 2011 May;145(4):596-606

Peptide Biology Laboratories, The Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.cell.2011.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129781PMC
May 2011

Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening.

Proc Natl Acad Sci U S A 2010 Dec 17;107(49):20941-6. Epub 2010 Nov 17.

The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.1011663107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000285PMC
December 2010

Practical 4'-phosphopantetheine active site discovery from proteomic samples.

J Proteome Res 2011 Jan 13;10(1):320-9. Epub 2010 Dec 13.

Department of Chemistry and Biochemistry, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego, La Jolla California 92093, USA.

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http://dx.doi.org/10.1021/pr100953bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042426PMC
January 2011

LDL receptor-related protein 1 regulates the abundance of diverse cell-signaling proteins in the plasma membrane proteome.

J Proteome Res 2010 Dec 28;9(12):6689-95. Epub 2010 Oct 28.

Department of Pathology, University of California San Diego School of Medicine, La Jolla, California 92093, United States.

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http://dx.doi.org/10.1021/pr1008288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997161PMC
December 2010

RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia.

Proc Natl Acad Sci U S A 2010 Feb 28;107(5):2189-94. Epub 2009 Dec 28.

Department of Pathology, Moores Cancer Center, University of California, San Diego, CA 92093-0803, USA.

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http://dx.doi.org/10.1073/pnas.0911646107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836678PMC
February 2010

Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis.

Cell 2010 Jan;140(1):49-61

The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.cell.2009.11.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885975PMC
January 2010

An orthogonal active site identification system (OASIS) for proteomic profiling of natural product biosynthesis.

ACS Chem Biol 2009 Nov;4(11):948-57

Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92037-0358, USA.

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http://dx.doi.org/10.1021/cb9002128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818308PMC
November 2009

Activity-based probes for monitoring postproline protease activity.

Chembiochem 2009 Sep;10(14):2361-6

Institut de Recerca Biomèdica, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1002/cbic.200900244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847404PMC
September 2009

Diversity of serine hydrolase activities of unchallenged and botrytis-infected Arabidopsis thaliana.

Mol Cell Proteomics 2009 May 11;8(5):1082-93. Epub 2009 Jan 11.

Plant Chemetics laboratory, Max Planck Institute for Plant Breeding Research, Carl-von-Linné Weg 10, 50829 Cologne, Germany.

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http://www.mcponline.org/lookup/doi/10.1074/mcp.M800494-MCP2
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http://dx.doi.org/10.1074/mcp.M800494-MCP200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689769PMC
May 2009

Selectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profiling.

Bioorg Med Chem Lett 2008 Nov 2;18(22):5838-41. Epub 2008 Jul 2.

The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA 92037, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0960894X0800741
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http://dx.doi.org/10.1016/j.bmcl.2008.06.091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634297PMC
November 2008

Forward chemical genetic approach identifies new role for GAPDH in insulin signaling.

Nat Chem Biol 2007 Jan 19;3(1):55-9. Epub 2006 Nov 19.

Department of Chemistry, New York University, New York, New York 10003, USA.

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http://dx.doi.org/10.1038/nchembio833DOI Listing
January 2007

An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling.

Chem Biol 2006 Oct;13(10):1041-50

The Skaggs Institute for Chemical Biology and Departments of Cell Biology and Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1016/j.chembiol.2006.08.008DOI Listing
October 2006

E4F1: a novel candidate factor for mediating BMI1 function in primitive hematopoietic cells.

Genes Dev 2006 Aug;20(15):2110-20

Laboratory of Molecular Genetics of Hematopoietic Stem Cells, Institut de Recherche en Immunologie et Cancérologie (IRIC), CP 6128 succursale Centre-Ville, Montréal, Québec, Canada.

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http://dx.doi.org/10.1101/gad.1453406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1536061PMC
August 2006

TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism.

Science 2006 Jun;312(5781):1763-6

Peptide Biology Laboratories and Gene Expression Laboratories, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1123374
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http://dx.doi.org/10.1126/science.1123374DOI Listing
June 2006

Activity-based protein profiling implicates urokinase activation as a key step in human fibrosarcoma intravasation.

J Biol Chem 2006 Jun 12;281(23):15997-6005. Epub 2006 Apr 12.

Department of Cell Biology, The Scripps Research Institute, La Jolla, California 92037, USA.

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http://www.scripps.edu/cravatt/pdf/Madsen2006.pdf
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http://www.jbc.org/cgi/doi/10.1074/jbc.M601223200
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http://dx.doi.org/10.1074/jbc.M601223200DOI Listing
June 2006

Proteomic profiling of metalloprotease activities with cocktails of active-site probes.

Nat Chem Biol 2006 May 26;2(5):274-81. Epub 2006 Mar 26.

The Skaggs Institute for Chemical Biology and Department of Cell Biology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, USA.

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http://www.nature.com/doifinder/10.1038/nchembio781
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http://dx.doi.org/10.1038/nchembio781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538544PMC
May 2006

Overview of affinity purification in combination with mass spectrometry.

CSH Protoc 2006 Dec 1;2006(7). Epub 2006 Dec 1.

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http://dx.doi.org/10.1101/pdb.top3DOI Listing
December 2006

Direct Enzymatic Digestion of Protein Complexes for MS Analysis.

CSH Protoc 2006 Dec 1;2006(7). Epub 2006 Dec 1.

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http://dx.doi.org/10.1101/pdb.prot4662DOI Listing
December 2006

A streamlined platform for high-content functional proteomics of primary human specimens.

Nat Methods 2005 Sep;2(9):691-7

The Skaggs Institute for Chemical Biology and Department of Cell Biology, The Scripps Research Institute, 10550 N. Torrey Pines Rd., La Jolla, California 92037, USA.

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http://www.nature.com/doifinder/10.1038/nmeth778
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http://dx.doi.org/10.1038/nmeth778DOI Listing
September 2005

Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex.

Eukaryot Cell 2005 Mar;4(3):577-87

Howard Hughes Medical Institute and Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://dx.doi.org/10.1128/EC.4.3.577-587.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087801PMC
March 2005

Breast cancer cell lines grown in vivo: what goes in isn't always the same as what comes out.

Cell Cycle 2005 Feb 21;4(2):253-5. Epub 2005 Feb 21.

The Skaggs Institute for Chemical Biology, Department of Cell Biology, The Scripps Research Institute, La Jolla, California 92037, USA.

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February 2005

The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector.

Cell 2004 Oct;119(1):61-74

Peptide Biology Laboratories, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.cell.2004.09.015DOI Listing
October 2004

Carcinoma and stromal enzyme activity profiles associated with breast tumor growth in vivo.

Proc Natl Acad Sci U S A 2004 Sep 8;101(38):13756-61. Epub 2004 Sep 8.

The Skaggs Institute for Chemical Biology and Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.0404727101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC518829PMC
September 2004