Sheri L Holmen

Sheri L Holmen

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Sheri L Holmen

Sheri L Holmen

Publications by authors named "Sheri L Holmen"

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Melanoma to Vitiligo: The Melanocyte in Biology & Medicine-Joint Montagna Symposium on the Biology of Skin/PanAmerican Society for Pigment Cell Research Annual Meeting.

J Invest Dermatol 2019 Jul 23. Epub 2019 Jul 23.

Department of Dermatology, Oregon Health & Science University, Portland, Oregon, USA; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA; Department of Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, Oregon, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.03.1164DOI Listing
July 2019

Mutant IDH1 Promotes Glioma Formation In Vivo.

Cell Rep 2018 05;23(5):1553-1564

Huntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, UT 84112, USA; Department of Surgery, University of Utah Health Sciences Center, Salt Lake City, UT 84112, USA; Department of Oncological Sciences, University of Utah Health Sciences Center, Salt Lake City, UT 84112, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.03.133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032974PMC
May 2018

Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.

Cancer Cell 2018 02;33(2):322-336.e8

Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Medical Department of Hematology, Oncology and Tumor Immunology, Virchow Campus, and Molekulares Krebsforschungszentrum, 13353 Berlin, Germany; Deutsches Konsortium für Translationale Krebsforschung (German Cancer Consortium), Partner Site Berlin, Germany.

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http://dx.doi.org/10.1016/j.ccell.2018.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977991PMC
February 2018

Exploiting Drug Addiction Mechanisms to Select against MAPKi-Resistant Melanoma.

Cancer Discov 2018 01 18;8(1):74-93. Epub 2017 Sep 18.

Division of Dermatology, Department of Medicine, University of California, Los Angeles, California.

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http://dx.doi.org/10.1158/2159-8290.CD-17-0682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456057PMC
January 2018

Resistance mechanisms to genetic suppression of mutant NRAS in melanoma.

Melanoma Res 2017 12;27(6):545-557

aThe Hormel Institute, University of Minnesota, Austin, Minnesota bDepartment of Medicine and Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Departments of cOncological Sciences dSurgery eDermatology fHuntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, Utah gDepartment of Tumor Biology, Tumor Biology hDepartment of Cutaneous Oncology, Cutaneous Oncology, Moffitt Cancer Center, Tampa, Florida iDepartment of Medicine, Lombardi Comprehensive Cancer Center, MedStar Georgetown University Hospital jDepartment of Global Health, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, DC kDepartment of Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1097/CMR.0000000000000403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683096PMC
December 2017

Melanoma Brain Metastasis: Mechanisms, Models, and Medicine.

Int J Mol Sci 2016 Sep 2;17(9). Epub 2016 Sep 2.

Department of Oncological Sciences, University of Utah Health Sciences Center, Salt Lake City, UT 84112, USA.

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http://dx.doi.org/10.3390/ijms17091468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037746PMC
September 2016

Melanoma metastases caught in the AKT.

Mol Cell Oncol 2016 Mar 18;3(2):e1128516. Epub 2016 Feb 18.

Department of Oncological Sciences, University of Utah Health Sciences Center, Salt Lake City, Utah, USA; Department of Surgery, University of Utah Health Sciences Center, Salt Lake City, Utah, USA; Huntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.

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http://dx.doi.org/10.1080/23723556.2015.1128516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905423PMC
March 2016

AKT1 Activation Promotes Development of Melanoma Metastases.

Cell Rep 2015 Nov 22;13(5):898-905. Epub 2015 Oct 22.

Department of Oncological Sciences, University of Utah Health Sciences Center, Salt Lake City, UT 84112, USA; Department of Surgery, University of Utah Health Sciences Center, Salt Lake City, UT 84112, USA; Huntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, UT 84112, USA. Electronic address:

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http://www.cell.com/cell-reports/pdf/S2211-1247(15)01082-7.p
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http://www.cell.com/cms/attachment/2040452974/2053964384/mmc
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http://linkinghub.elsevier.com/retrieve/pii/S221112471501082
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http://dx.doi.org/10.1016/j.celrep.2015.09.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646731PMC
November 2015

Gα13 mediates human cytomegalovirus-encoded chemokine receptor US28-induced cell death in melanoma.

Int J Cancer 2015 Sep 16;137(6):1503-8. Epub 2015 Mar 16.

Cancer Biology Unit, Department of Dermatology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1002/ijc.29506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496263PMC
September 2015

The BRAF kinase domain promotes the development of gliomas in vivo.

Genes Cancer 2015 Jan;6(1-2):9-18

Hormel Institute, University of Minnesota, Austin, Minnesota, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362480PMC
http://dx.doi.org/10.18632/genesandcancer.48DOI Listing
January 2015

Akt signaling accelerates tumor recurrence following ras inhibition in the context of ink4a/arf loss.

Genes Cancer 2013 Nov;4(11-12):476-85

Department of Surgery, University of Utah, Salt Lake City, UT, USA ; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.

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http://dx.doi.org/10.1177/1947601913513268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877666PMC
November 2013

IDH1 and IDH2 mutations in gliomas.

Curr Neurol Neurosci Rep 2013 May;13(5):345

Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA.

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http://link.springer.com/10.1007/s11910-013-0345-4
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http://dx.doi.org/10.1007/s11910-013-0345-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109985PMC
May 2013

Familial melanoma-associated mutations in p16 uncouple its tumor-suppressor functions.

J Invest Dermatol 2013 Apr 29;133(4):1043-51. Epub 2012 Nov 29.

Department of Oncological Sciences, University of Utah Health Sciences Center, Salt Lake City, UT, USA.

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http://dx.doi.org/10.1038/jid.2012.401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594444PMC
April 2013

Animal models of melanoma: a somatic cell gene delivery mouse model allows rapid evaluation of genes implicated in human melanoma.

Chin J Cancer 2011 Mar;30(3):153-62

Department of Drug and Target Discovery, Nevada Cancer Institute, Las Vegas, NV 89135, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013311PMC
March 2011

Akt signaling is required for glioblastoma maintenance in vivo.

Am J Cancer Res 2011 ;1(2):155-167

Nevada Cancer Institute, Las Vegas, NV 89135, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142953PMC
January 2011

Inhibition of Marek's disease virus replication by retroviral vector-based RNA interference.

Virology 2008 Aug;377(2):265-72

Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824, USA.

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http://dx.doi.org/10.1016/j.virol.2008.03.019DOI Listing
August 2008

Inhibition of avian leukosis virus replication by vector-based RNA interference.

Virology 2007 Sep 9;365(2):464-72. Epub 2007 May 9.

Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824, USA.

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http://dx.doi.org/10.1016/j.virol.2007.04.013DOI Listing
September 2007

APC inhibits ERK pathway activation and cellular proliferation induced by RAS.

J Cell Sci 2006 Mar 14;119(Pt 5):819-27. Epub 2006 Feb 14.

Division of Molecular and Cellular Biology, Department of Biotechnology, Yonsei University, Seoul 120-752, Korea.

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http://healthcare.utah.edu/huntsmancancerinstitute/research/
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http://jcs.biologists.org/cgi/doi/10.1242/jcs.02779
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http://dx.doi.org/10.1242/jcs.02779DOI Listing
March 2006

Essential role for Ras signaling in glioblastoma maintenance.

Cancer Res 2005 Sep;65(18):8250-5

Molecular Medicine and Virology Group, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-1173DOI Listing
September 2005

Essential role of beta-catenin in postnatal bone acquisition.

J Biol Chem 2005 Jun 31;280(22):21162-8. Epub 2005 Mar 31.

Laboratory of Cell Signaling and Carcinogenesis, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.

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http://dx.doi.org/10.1074/jbc.M501900200DOI Listing
June 2005

Wnt-independent activation of beta-catenin mediated by a Dkk1-Fz5 fusion protein.

Biochem Biophys Res Commun 2005 Mar;328(2):533-9

Laboratory of Cell Signaling and Carcinogenesis, Van Andel Research Institute, Grand Rapids, MI 49503, USA.

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http://dx.doi.org/10.1016/j.bbrc.2005.01.009DOI Listing
March 2005

Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6.

J Bone Miner Res 2004 Dec 13;19(12):2033-40. Epub 2004 Sep 13.

Laboratory of Cell Signaling and Carcinogenesis, Van Andel Research Institute, Grand Rapids, Michigan, USA.

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http://dx.doi.org/10.1359/JBMR.040907DOI Listing
December 2004

Delivery of short hairpin RNA sequences by using a replication-competent avian retroviral vector.

J Virol 2004 May;78(9):4914-6

Laboratory of Tumor Metastasis and Angiogenesis, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC387706PMC
http://dx.doi.org/10.1128/jvi.78.9.4914-4916.2004DOI Listing
May 2004

A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling.

J Biol Chem 2002 Sep 16;277(38):34727-35. Epub 2002 Jul 16.

Laboratory of Cell Signaling and Carcinogenesis, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M204989200
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http://dx.doi.org/10.1074/jbc.M204989200DOI Listing
September 2002