Publications

Selective oxidation of aliphatic C-H bonds in alkylphenols by a chemomimetic biocatalytic system.
Proc Natl Acad Sci U S A 2017 Jun 12;114(26):E5129-E5137. Epub 2017 Jun 12.
Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong 266101, China;

Mutagenesis and redox partners analysis of the P450 fatty acid decarboxylase OleT.
Sci Rep 2017 Mar 9;7:44258. Epub 2017 Mar 9.
Shandong Provincial Key Laboratory of Synthetic Biology, CAS Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189 Songling Road, Qingdao 266101, China.

In vitro reconstitution of the cyclosporine specific P450 hydroxylases using heterologous redox partner proteins.
J Ind Microbiol Biotechnol 2017 Feb 25;44(2):161-166. Epub 2016 Nov 25.
Shandong Provincial Key Laboratory of Synthetic Biology, CAS Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China.

Identification of an unexpected shunt pathway product provides new insights into tirandamycin biosynthesis.
Tetrahedron Lett 2016 Dec 19;57(52):5919-5923. Epub 2016 Nov 19.
Shandong Provincial Key Laboratory of Synthetic Biology, and CAS Key Laboratory of Biofuels at Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong 266101, China.

Reconstitution of the In Vitro Activity of the Cyclosporine-Specific P450 Hydroxylase from Sebekia benihana and Development of a Heterologous Whole-Cell Biotransformation System.
Appl Environ Microbiol 2015 Sep 6;81(18):6268-75. Epub 2015 Jul 6.
Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China

Metabolic engineering of 2-phenylethanol pathway producing fragrance chemical and reducing lignin in Arabidopsis.
Plant Cell Rep 2015 Aug 21;34(8):1331-42. Epub 2015 Apr 21.
Key Laboratory of Biofuels and Shandong Provincial Key Laboratory of Energy Genetics, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, 266101, China,

Functional characterization of MpaG', the O-methyltransferase involved in the biosynthesis of mycophenolic acid.
Chembiochem 2015 Mar 28;16(4):565-9. Epub 2015 Jan 28.
Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Energy Genetics, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, 189 Songling Road, Qingdao, Shandong 266101 (China).

Engineering self-sufficient aldehyde deformylating oxygenases fused to alternative electron transfer systems for efficient conversion of aldehydes into alkanes.
Chem Commun (Camb) 2014 Apr;50(33):4299-301
Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Energy Genetics, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189 Songling Road, Qingdao 266101, China.

Integrated lipase production and in situ biodiesel synthesis in a recombinant Pichia pastoris yeast: an efficient dual biocatalytic system composed of cell free enzymes and whole cell catalysts.
Biotechnol Biofuels 2014 Apr 8;7(1):55. Epub 2014 Apr 8.
Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Energy Genetics, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No, 189 Songling Road, Qingdao, Shandong 266101, China.

New reactions and products resulting from alternative interactions between the P450 enzyme and redox partners.
J Am Chem Soc 2014 Mar 25;136(9):3640-6. Epub 2014 Feb 25.
CAS Key Laboratory of Biofuels, and Shandong Provincial Key Laboratory of Energy Genetics, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences , Qingdao, Shandong 266101, China.

Hydrogen peroxide-independent production of α-alkenes by OleTJE P450 fatty acid decarboxylase.
Biotechnol Biofuels 2014 Feb 24;7(1):28. Epub 2014 Feb 24.
Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Energy Genetics, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No, 189 Songling Road, Qingdao, Shandong 266101, China.

A novel and robust recombinant Pichia pastoris yeast whole cell biocatalyst with intracellular overexpression of a Thermomyces lanuginosus lipase: preparation, characterization and application in biodiesel production.
Bioresour Technol 2014 Jan 18;151:43-8. Epub 2013 Oct 18.
Key Laboratory of Biofuels and Shandong Provincial Key Laboratory of Energy Genetics, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, 189 Songling Road, Qingdao, Shandong 266101, China. Electronic address:

Characterization of the bafilomycin biosynthetic gene cluster from Streptomyces lohii.
Chembiochem 2013 Feb 29;14(3):301-6. Epub 2013 Jan 29.
Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Energy Genetics, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, 189 Songling Road, Qingdao, Shandong 266101, PR China.


Assembly of lipase and P450 fatty acid decarboxylase to constitute a novel biosynthetic pathway for production of 1-alkenes from renewable triacylglycerols and oils.
Biotechnol Biofuels 2015 26;8:34. Epub 2015 Feb 26.
Key Laboratory of Biofuels, and Shandong Provincial Key Laboratory of Energy Genetics, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189 Songling Road, 266101 Qingdao, Shandong China.

Improving the Secretory Expression of an -Galactosidase from Aspergillus niger in Pichia pastoris.
PLoS One 2016 22;11(8):e0161529. Epub 2016 Aug 22.
Shandong Provincial Key Laboratory of Synthetic Biology, and CAS Key Laboratory of Biofuels at Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189 Songling Road, Qingdao, Shandong 266101, China.

Complete elucidation of the late steps of bafilomycin biosynthesis in.
J Biol Chem 2017 04 14;292(17):7095-7104. Epub 2017 Mar 14.
From the Shandong Provincial Key Laboratory of Synthetic Biology, and CAS Key Laboratory of Biofuels at Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong 266101,

In vitro oxidative decarboxylation of free fatty acids to terminal alkenes by two new P450 peroxygenases.
Biotechnol Biofuels 2017 7;10:208. Epub 2017 Sep 7.
Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189 Songling Road, Qingdao, 266101 Shandong China.

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