Publications by authors named "Shen Gu"

57Publications

Microcystin-leucine-arginine induces liver fibrosis by activating the Hedgehog pathway in hepatic stellate cells.

Biochem Biophys Res Commun 2020 Sep 25. Epub 2020 Sep 25.

Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, Jiangsu, 210093, China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, Jiangsu, 210093, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2020.09.075DOI Listing
September 2020

Integrated sequencing and array comparative genomic hybridization in familial Parkinson disease.

Neurol Genet 2020 Oct 28;6(5):e498. Epub 2020 Jul 28.

Department of Molecular and Human Genetics (L.A.R., R.D., B.Y., S.G., V.K., E.H., A.S., E.Y., C.Z., X.S., H.D., T.G., Z.C.A., A.T., C.S., W.B., J.E.P., J.R.L., J.M.S.), Department of Neurology (I.A.-D., J.J., J.M.S.), and Human Genome Sequencing Center (S.N.J., D.M.M., J.R.L.), Baylor College of Medicine, Houston, TX; Baylor Genetics (W.B.), Houston, TX; Department of Neurology (O.A.R.), Department of Neuroscience (O.A.R.), and Department of Clinical Genomics (O.A.R.), Mayo Clinic, Jacksonville, FL; Parkinson's Disease Center and Movement Disorders Clinic (J.J.) and Department of Pediatrics (J.R.L., J.M.S.), Baylor College of Medicine, Houston, TX; Department of Pediatrics (J.R.L.), Texas Children's Hospital, Houston; Department of Neuroscience (J.M.S.), Baylor College of Medicine, Houston, TX; and Jan and Dan Duncan Neurological Research Institute (J.M.S.), Texas Children's Hospital, Houston.

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http://dx.doi.org/10.1212/NXG.0000000000000498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413630PMC
October 2020

Prognostic value of precise hepatic pedicle dissection in anatomical resection for patients with hepatocellular carcinoma.

Medicine (Baltimore) 2020 Mar;99(10):e19475

Department of Hepatopancreatobiliary Surgery, Drum Tower Hospital, Medical School of Nanjing University.

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http://dx.doi.org/10.1097/MD.0000000000019475DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478661PMC
March 2020

Expression analysis of microRNAs and mRNAs in myofibroblast differentiation of lung resident mesenchymal stem cells.

Differentiation 2020 Mar - Apr;112:10-16. Epub 2019 Dec 10.

Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, Jiangsu, 210093, China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, Jiangsu, 210093, China. Electronic address:

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http://dx.doi.org/10.1016/j.diff.2019.11.002DOI Listing
December 2019

The role of ERK-RSK signaling in the proliferation of intrahepatic biliary epithelial cells exposed to microcystin-leucine arginine.

Biochem Biophys Res Commun 2020 01 31;521(2):492-498. Epub 2019 Oct 31.

Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, Jiangsu, 210093, China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, Jiangsu, 210093, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.10.143DOI Listing
January 2020

LRRK2 Is Associated with Recurrence-Free Survival in Intrahepatic Cholangiocarcinoma and Downregulation of LRRK2 Suppresses Tumor Progress In Vitro.

Dig Dis Sci 2020 02 5;65(2):500-508. Epub 2019 Sep 5.

Department of Hepatopancreatobiliary Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, Jiangsu Province, China.

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http://dx.doi.org/10.1007/s10620-019-05806-0DOI Listing
February 2020

Inhibition of circHIPK3 prevents angiotensin II-induced cardiac fibrosis by sponging miR-29b-3p.

Int J Cardiol 2019 10 2;292:188-196. Epub 2019 Apr 2.

Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200800, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2019.04.006DOI Listing
October 2019

[Standards and regulations for reporting clinical genetic testing results in the United States].

Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2019 Jan;36(1):65-91

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA O2115, USA. Email:

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http://dx.doi.org/10.3760/cma.j.issn.1003-9406.2019.01.011DOI Listing
January 2019

[Recommendation for standardized certification of the directors of genetic diagnostics laboratories].

Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2019 Jan;36(1):32-36

Hayward Genetics Center, Tulane University School of Medicine, New Orleans, LA 70112, USA. Email:

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http://dx.doi.org/10.3760/cma.j.issn.1003-9406.2019.01.006DOI Listing
January 2019

Comparison of multi-lineage differentiation of hiPSCs reveals novel miRNAs that regulate lineage specification.

Sci Rep 2018 06 25;8(1):9630. Epub 2018 Jun 25.

CUHK-CAS GIBH Joint Research Laboratory on Stem Cell and Regenerative Medicine, School of Biomedical Sciences, the Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR.

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http://dx.doi.org/10.1038/s41598-018-27719-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018499PMC
June 2018

Predicting human genes susceptible to genomic instability associated with /-mediated rearrangements.

Genome Res 2018 08 15;28(8):1228-1242. Epub 2018 Jun 15.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1101/gr.229401.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071635PMC
August 2018

Prognostic value and preoperative predictors of microvascular invasion in solitary hepatocellular carcinoma ≤ 5 cm without macrovascular invasion.

Oncotarget 2017 Sep 22;8(37):61203-61214. Epub 2017 May 22.

Department of Hepatopancreatobiliary Surgery, Nanjing Medical University Affiliated Wuxi Second People's Hospital, Wuxi, Jiangsu, China.

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http://dx.doi.org/10.18632/oncotarget.18049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617417PMC
September 2017

Divergent Levels of Marker Chromosomes in an hiPSC-Based Model of Psychosis.

Stem Cell Reports 2017 03 16;8(3):519-528. Epub 2017 Feb 16.

Departments of Neuroscience, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY 10029, USA; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY 10029, USA; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355568PMC
March 2017

Mutation Detection of Fibroblast Growth Factor Receptor 3 for Infiltrative Hepatocellular Carcinoma by Whole-Exome Sequencing.

Dig Dis Sci 2017 02 5;62(2):407-417. Epub 2017 Jan 5.

Department of Hepatopancreatobiliary Surgery, Drum Tower Hospital, Medical School of Nanjing University, Zhongshan Road 321, Nanjing, 210008, Jiangsu Province, China.

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http://dx.doi.org/10.1007/s10620-016-4408-7DOI Listing
February 2017

[Clinical study for stroke treated with meridian-collateral diagnosis and therapy by ].

Zhongguo Zhen Jiu 2016 Oct;36(10):1023-1026

Huguosi TCM Hospital, Beijing University of CM, Beijing 100035, China.

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http://dx.doi.org/10.13703/j.0255-2930.2016.10.005DOI Listing
October 2016

Anatomical versus non-anatomical resection for solitary hepatocellular carcinoma without macroscopic vascular invasion: A propensity score matching analysis.

J Gastroenterol Hepatol 2017 Apr;32(4):870-878

Department of Hepatopancreatobiliary Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, Jiangsu, China.

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http://dx.doi.org/10.1111/jgh.13603DOI Listing
April 2017

Primary immunodeficiency diseases: Genomic approaches delineate heterogeneous Mendelian disorders.

Authors:
Asbjørg Stray-Pedersen Hanne Sørmo Sorte Pubudu Samarakoon Tomasz Gambin Ivan K Chinn Zeynep H Coban Akdemir Hans Christian Erichsen Lisa R Forbes Shen Gu Bo Yuan Shalini N Jhangiani Donna M Muzny Olaug Kristin Rødningen Ying Sheng Sarah K Nicholas Lenora M Noroski Filiz O Seeborg Carla M Davis Debra L Canter Emily M Mace Timothy J Vece Carl E Allen Harshal A Abhyankar Philip M Boone Christine R Beck Wojciech Wiszniewski Børre Fevang Pål Aukrust Geir E Tjønnfjord Tobias Gedde-Dahl Henrik Hjorth-Hansen Ingunn Dybedal Ingvild Nordøy Silje F Jørgensen Tore G Abrahamsen Torstein Øverland Anne Grete Bechensteen Vegard Skogen Liv T N Osnes Mari Ann Kulseth Trine E Prescott Cecilie F Rustad Ketil R Heimdal John W Belmont Nicholas L Rider Javier Chinen Tram N Cao Eric A Smith Maria Soledad Caldirola Liliana Bezrodnik Saul Oswaldo Lugo Reyes Francisco J Espinosa Rosales Nina Denisse Guerrero-Cursaru Luis Alberto Pedroza Cecilia M Poli Jose L Franco Claudia M Trujillo Vargas Juan Carlos Aldave Becerra Nicola Wright Thomas B Issekutz Andrew C Issekutz Jordan Abbott Jason W Caldwell Diana K Bayer Alice Y Chan Alessandro Aiuti Caterina Cancrini Eva Holmberg Christina West Magnus Burstedt Ender Karaca Gözde Yesil Hasibe Artac Yavuz Bayram Mehmed Musa Atik Mohammad K Eldomery Mohammad S Ehlayel Stephen Jolles Berit Flatø Alison A Bertuch I Celine Hanson Victor W Zhang Lee-Jun Wong Jianhong Hu Magdalena Walkiewicz Yaping Yang Christine M Eng Eric Boerwinkle Richard A Gibbs William T Shearer Robert Lyle Jordan S Orange James R Lupski

J Allergy Clin Immunol 2017 01 16;139(1):232-245. Epub 2016 Jul 16.

Baylor-Hopkins Center for Mendelian Genomics of the Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Tex; Department of Pediatrics, Baylor College of Medicine, and Texas Children's Hospital, Houston, Tex; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Tex; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Tex. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.05.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222743PMC
January 2017

miR-877-3p targets Smad7 and is associated with myofibroblast differentiation and bleomycin-induced lung fibrosis.

Sci Rep 2016 07 22;6:30122. Epub 2016 Jul 22.

Immunology and Reproduction Biology Laboratory &State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, Jiangsu 210093, China.

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http://dx.doi.org/10.1038/srep30122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957095PMC
July 2016

The toxic effects of microcystin-LR on mouse lungs and alveolar type II epithelial cells.

Toxicon 2016 Jun 16;115:81-8. Epub 2016 Mar 16.

Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, Jiangsu 210093, China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, Jiangsu 210093, China. Electronic address:

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http://dx.doi.org/10.1016/j.toxicon.2016.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5169163PMC
June 2016

Hutterite-type cataract maps to chromosome 6p21.32-p21.31, cosegregates with a homozygous mutation in LEMD2, and is associated with sudden cardiac death.

Mol Genet Genomic Med 2016 Jan 14;4(1):77-94. Epub 2015 Nov 14.

Department of Molecular and Human GeneticsBaylor College of MedicineHoustonTexas; Department of PediatricsBaylor College of MedicineHoustonTexas; Texas Children's HospitalHoustonTexas; Department of OphthalmologyBaylor College of MedicineHoustonTexas; Department of MedicineBaylor College of MedicineHoustonTexas.

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http://dx.doi.org/10.1002/mgg3.181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707028PMC
January 2016

Nonrecurrent 17p11.2p12 Rearrangement Events that Result in Two Concomitant Genomic Disorders: The PMP22-RAI1 Contiguous Gene Duplication Syndrome.

Am J Hum Genet 2015 Nov;97(5):691-707

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA; Texas Children's Hospital, Houston, TX 77030, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297150040
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http://dx.doi.org/10.1016/j.ajhg.2015.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667131PMC
November 2015

Alu-mediated diverse and complex pathogenic copy-number variants within human chromosome 17 at p13.3.

Hum Mol Genet 2015 Jul 23;24(14):4061-77. Epub 2015 Apr 23.

Department of Molecular & Human Genetics, Department of Pediatrics and Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA, Texas Children's Hospital, Houston, TX 77030, USA and

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http://dx.doi.org/10.1093/hmg/ddv146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476451PMC
July 2015

Nanoparticle delivery of stable miR-199a-5p agomir improves the osteogenesis of human mesenchymal stem cells via the HIF1a pathway.

Biomaterials 2015 Jun 14;53:239-50. Epub 2015 Mar 14.

School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2015.02.071DOI Listing
June 2015

Targeted inhibition of disheveled PDZ domain via NSC668036 depresses fibrotic process.

Exp Cell Res 2015 Feb 5;331(1):115-122. Epub 2014 Nov 5.

Immunology and Reproduction Biology Laboratory, Medical School, Nanjing University, Nanjing, Hankou Road 22, Jiangsu 210093, China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, Jiangsu 210093, China; State Key Laboratory of Analytical Chemistry for Life Science, Nanjing University, Nanjing, Jiangsu 210093, China. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2014.10.023DOI Listing
February 2015

A miR-199a/miR-214 self-regulatory network via PSMD10, TP53 and DNMT1 in testicular germ cell tumor.

Sci Rep 2014 Sep 18;4:6413. Epub 2014 Sep 18.

The Chinese University of Hong Kong - Shandong University Joint Laboratory on Reproductive Genetics, School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1038/srep06413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166711PMC
September 2014

The working lives of nurse teachers in mainland China and the United Kingdom: a questionnaire survey.

Nurse Educ Today 2014 May 27;34(5):730-7. Epub 2013 Aug 27.

2nd Military Medical University, School of Health & Hygiene Services, 800 Xiang Yin Road, Shanghai 200433, China. Electronic address:

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http://dx.doi.org/10.1016/j.nedt.2013.08.010DOI Listing
May 2014

LIF-dependent primitive neural stem cells derived from mouse ES cells represent a reversible stage of neural commitment.

Stem Cell Res 2013 Nov 2;11(3):1091-102. Epub 2013 Aug 2.

Key Laboratory for Regenerative Medicine, Ministry of Education, School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1016/j.scr.2013.07.007DOI Listing
November 2013

microRNA-199a-3p, DNMT3A, and aberrant DNA methylation in testicular cancer.

Epigenetics 2014 Jan 19;9(1):119-28. Epub 2013 Aug 19.

Key Laboratory for Regenerative Medicine; Ministry of Education; School of Biomedical Sciences; Faculty of Medicine; The Chinese University of Hong Kong; Hong Kong, P.R. China.

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http://dx.doi.org/10.4161/epi.25799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928174PMC
January 2014

Antibacterial properties and bioactivity of HACC- and HACC-Zein-modified mesoporous bioactive glass scaffolds.

J Mater Chem B 2013 Feb 28;1(5):685-692. Epub 2012 Nov 28.

Changhai Hospital, Department of Orthopedics, the Second Military Medical University, 168 Changhai Road, Shanghai 200433, China.

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http://dx.doi.org/10.1039/c2tb00102kDOI Listing
February 2013

Prehospital emergency care in Shanghai: present and future.

J Emerg Med 2012 Dec 6;43(6):1132-7. Epub 2012 Oct 6.

Emergency Nursing Department, School of Nursing, 2(nd) Military Medical University, Shanghai, People's Republic of China.

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http://dx.doi.org/10.1016/j.jemermed.2012.02.067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126957PMC
December 2012

Flexible and versatile as a chameleon-sophisticated functions of microRNA-199a.

Int J Mol Sci 2012 9;13(7):8449-66. Epub 2012 Jul 9.

School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China; E-Mail:

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http://www.mdpi.com/1422-0067/13/7/8449
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http://dx.doi.org/10.3390/ijms13078449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430244PMC
August 2015

Confronting the challenges of emergency medical service in Shanghai.

Resuscitation 2011 Jun 16;82(6):788-9. Epub 2011 Mar 16.

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http://dx.doi.org/10.1016/j.resuscitation.2011.01.030DOI Listing
June 2011

A Survey of Solvents for the Conrad-Limpach Synthesis of 4-Hydroxyquinolones.

Synth Commun 2009 Jan;39(9):5193-5196

Microbiotix, Inc. One Innovation Drive Worcester, MA, 01605.

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http://dx.doi.org/10.1080/00397910802542044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744084PMC
January 2009

[Influence of therapeutic effect of acupoint sticking at Shenque (CV 8) for treatment of stroke patients].

Zhongguo Zhen Jiu 2009 Sep;29(9):695-8

Department, Huguosi TCM Hospital Affiliated to Beijing University of CM, Beijing 100035, China.

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September 2009

Enantioselective PhSe-group-transfer tandem radical cyclization reactions catalyzed by a chiral Lewis acid.

Angew Chem Int Ed Engl 2005 Dec;45(2):255-8

Department of Chemistry, University of Hong Kong, Pokfulam Road, Hong Kong, P. R. China.

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http://dx.doi.org/10.1002/anie.200503056DOI Listing
December 2005

Atom-transfer tandem radical cyclization reactions promoted by lewis acids.

Angew Chem Int Ed Engl 2002 Aug;41(16):3014-7

Department of Chemistry, The University of Hong Kong Pokfulam Road, P. R. China.

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http://dx.doi.org/10.1002/1521-3773(20020816)41:16<3014::AID-ANIE3014>3.0.CO;2-JDOI Listing
August 2002