Shelly Heimfeld

Shelly Heimfeld

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Shelly Heimfeld

Shelly Heimfeld

Publications by authors named "Shelly Heimfeld"

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Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma.

N Engl J Med 2018 01;378(1):35-47

From the Duke University Medical Center (K.M.S., O.C., E.W.S.C.) and RTI International (D.W.), Durham, and Rho Federal Systems Division, Chapel Hill (L.K.-E., A.P., B.E., S.C.) - all in North Carolina; National Institute of Allergy and Infectious Diseases, Bethesda, MD (E.A.G., B.W., L.M.G., J.S.G.); Colorado Blood Cancer Institute, Denver (P.A.M., R.A.N.); University of Texas McGovern Medical School (M.D.M.) and M.D. Anderson Cancer Center (C.H.) - both in Houston; Vanderbilt University, Nashville (L.J.C., K.P.); University of Michigan, Ann Arbor (D.K., J.R.S.); Case Western Reserve University and University Hospitals, Cleveland (R.J.F.); University of Alabama, Birmingham (S.M.); Boston University, Boston (R.W.S.); University of Virginia, Charlottesville (K.B.); University of Washington (M.H.W., D.E.F.) and the Fred Hutchinson Cancer Research Center (G.E.G., S.H.) - both in Seattle; University of California, Los Angeles, Los Angeles (J.G., S.K., D.E.F.); City of Hope National Medical Center, Duarte, CA (S.F.); Medical University of South Carolina, Charleston (R.M.S.); Mayo Clinic, Scottsdale, AZ (L.G.); University of Calgary, Calgary, AB, Canada (J.S., S.L.); Washington University, St. Louis (R.B.); Medical College of Wisconsin, Milwaukee (M.E.C., C.K.-T.); Ottawa Hospital Research Institute, Ottawa (C.B.); University of Pittsburgh, Pittsburgh (T.M., R.T.D.); and University of Toledo Medical Center, Toledo, OH (M.B.K.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846574PMC
http://dx.doi.org/10.1056/nejmoa1703327DOI Listing
January 2018

Manufacture of Autologous CD34 Selected Grafts in the NIAID-Sponsored HALT-MS and SCOT Multicenter Clinical Trials for Autoimmune Diseases.

Biol Blood Marrow Transplant 2017 Sep 30;23(9):1463-1472. Epub 2017 Jun 30.

Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2017.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761325PMC
September 2017

Durable Molecular Remissions in Chronic Lymphocytic Leukemia Treated With CD19-Specific Chimeric Antigen Receptor-Modified T Cells After Failure of Ibrutinib.

J Clin Oncol 2017 Sep 17;35(26):3010-3020. Epub 2017 Jul 17.

Cameron J. Turtle, Kevin A. Hay, Laïla-Aïcha Hanafi, Shelly Heimfeld, Stanley R. Riddell, and David G. Maloney, Fred Hutchinson Cancer Research Center; Cameron J. Turtle, Sindhu Cherian, Xueyan Chen, Brent Wood, Stanley R. Riddell, and David G. Maloney, University of Washington; Daniel Li, Juno Therapeutics, Seattle, WA; and Arletta Lozanski and John C. Byrd, The Ohio State University, Columbus, OH.

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http://dx.doi.org/10.1200/JCO.2017.72.8519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590803PMC
September 2017

Real Time Immunophenotyping of Leukocyte Subsets Early after Double Cord Blood Transplantation Predicts Graft Function.

Biol Blood Marrow Transplant 2017 Mar 19;23(3):412-419. Epub 2016 Dec 19.

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Department of Pediatrics, University of Washington, Seattle, Washington. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10838791163118
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http://dx.doi.org/10.1016/j.bbmt.2016.12.625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348257PMC
March 2017

Semi-automated closed system manufacturing of lentivirus gene-modified haematopoietic stem cells for gene therapy.

Nat Commun 2016 10 20;7:13173. Epub 2016 Oct 20.

Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, Washington 98109, USA.

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http://dx.doi.org/10.1038/ncomms13173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080442PMC
October 2016

Association of fludarabine pharmacokinetic/dynamic biomarkers with donor chimerism in nonmyeloablative HCT recipients.

Cancer Chemother Pharmacol 2015 Jul 17;76(1):85-96. Epub 2015 May 17.

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA,

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http://dx.doi.org/10.1007/s00280-015-2768-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489995PMC
July 2015

MIR144 and MIR451 regulate human erythropoiesis via RAB14.

Br J Haematol 2015 Feb 14;168(4):583-97. Epub 2014 Oct 14.

Departments of Physiology and Pediatrics, Center for Stem Cell Biology & Regenerative Medicine, Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1111/bjh.13164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314389PMC
February 2015

Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8(+) T cells.

J Immunother Cancer 2014 14;2(1):36. Epub 2014 Oct 14.

Clinical Research Division, D3-100 Fred Hutchinson Cancer Research Center, 1100 Fairview Ave, Seattle, WA 98109 USA ; Department of Medicine, University of Washington, Seattle, WA USA ; Department of Melanoma Medical Oncology, UT MD Anderson Cancer Center, 7455 Fannin St, Unit 904, Houston, TX 77054 USA.

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http://dx.doi.org/10.1186/s40425-014-0036-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196009PMC
October 2014

Correlation of infused CD3+CD8+ cells with single-donor dominance after double-unit cord blood transplantation.

Biol Blood Marrow Transplant 2013 Jan 16;19(1):156-60. Epub 2012 Sep 16.

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

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http://dx.doi.org/10.1016/j.bbmt.2012.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462195PMC
January 2013

Early CD3 peripheral blood chimerism predicts the long-term engrafting unit following myeloablative double-cord blood transplantation.

Biol Blood Marrow Transplant 2012 Aug 8;18(8):1243-9. Epub 2012 Feb 8.

Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N., Seattle, WA 98109, USA.

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http://dx.doi.org/10.1016/j.bbmt.2012.01.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680594PMC
August 2012

Improved immunomagnetic enrichment of CD34(+) cells from umbilical cord blood using the CliniMACS cell separation system.

Cytotherapy 2012 Aug 2;14(7):818-22. Epub 2012 May 2.

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

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http://dx.doi.org/10.3109/14653249.2012.681040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930473PMC
August 2012

A pilot pharmacologic biomarker study of busulfan and fludarabine in hematopoietic cell transplant recipients.

Cancer Chemother Pharmacol 2012 Jan 11;69(1):263-72. Epub 2011 Sep 11.

School of Pharmacy, University of Washington, Box 357630, Seattle, WA 98195-7630, USA.

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http://dx.doi.org/10.1007/s00280-011-1736-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280823PMC
January 2012

A dilution-filtration system for removing cryoprotective agents.

J Biomech Eng 2011 Feb;133(2):021007

School of Mechatronics Engineering, University of Electronic Science and Technology of China, Chengdu, Sichuan 610054, China.

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http://dx.doi.org/10.1115/1.4003317DOI Listing
February 2011

Theoretical and experimental analyses of optimal experimental design for determination of hydraulic conductivity of cell membrane.

Biopreserv Biobank 2010 Sep;8(3):147-52

1 School of Mechatronics Engineering, University of Electronic Science and Technology of China , Chengdu, Sichuan, China .

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http://dx.doi.org/10.1089/bio.2010.0011DOI Listing
September 2010

Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution.

Nat Med 2010 Feb 17;16(2):232-6. Epub 2010 Jan 17.

Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

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http://dx.doi.org/10.1038/nm.2080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819359PMC
February 2010

A steady-state mass transfer model of removing CPAs from cryopreserved blood with hollow fiber modules.

J Biomech Eng 2010 Jan;132(1):011002

Department of Mechanical Engineering, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1115/1.4000110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882658PMC
January 2010

Cryopreservation of Peripheral Blood Stem Cells Using a Box-in-Box Cooling Device.

Biopreserv Biobank 2009 Jun;7(2):107-14

School of Mechatronics Engineering, University of Electronic Science and Technology of China, Chengdu, Sichuan, People's Republic of China. , Department of Mechanical Engineering, University of Washington, Seattle, Washington.

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http://www.liebertpub.com/doi/10.1089/bio.2009.0005
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http://dx.doi.org/10.1089/bio.2009.0005DOI Listing
June 2009

Intracellular disposition of fludarabine triphosphate in human natural killer cells.

Cancer Chemother Pharmacol 2009 Apr 10;63(5):959-64. Epub 2008 Sep 10.

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://dx.doi.org/10.1007/s00280-008-0829-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648818PMC
April 2009

Imatinib inhibition of fludarabine uptake in T-lymphocytes.

Cancer Chemother Pharmacol 2008 Sep 15;62(4):735-9. Epub 2007 Nov 15.

Department of Pharmacy, University of Washington, Box 357630, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1007/s00280-007-0629-yDOI Listing
September 2008

An Application of Stream Imaging Technique in the Study of Osmotic Behaviors of Multiple Cells.

Cell Preserv Technol 2008 Jun;6(2):125-132

Department of Mechanical Engineering, University of Washington, Seattle, WA.

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http://dx.doi.org/10.1089/cpt.2008.0002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879654PMC
June 2008

Development of a microfluidic device for determination of cell osmotic behavior and membrane transport properties.

Cryobiology 2007 Dec 24;55(3):200-9. Epub 2007 Aug 24.

Department of Mechanical Engineering, University of Washington, ME Building R254, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1016/j.cryobiol.2007.08.001DOI Listing
December 2007

CD34+ hematopoietic stem-progenitor cell microRNA expression and function: a circuit diagram of differentiation control.

Proc Natl Acad Sci U S A 2007 Feb 9;104(8):2750-5. Epub 2007 Feb 9.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, MD 21204, USA.

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http://dx.doi.org/10.1073/pnas.0610983104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796783PMC
February 2007

Collection of blood stem cells from patients with sickle cell anemia.

Blood Cells Mol Dis 2005 Nov-Dec;35(3):384-8. Epub 2005 Aug 26.

Division of Hematology, Department of Medicine, University of Washington School of Medicine, Mailstop 357710, HSB, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1016/j.bcmd.2005.06.014DOI Listing
April 2006

HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding.

Stem Cells 2006 Apr 2;24(4):876-88. Epub 2006 Mar 2.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Department of Oncology, Bunting-Blaustein Cancer Research Building, Room 2M44, 1650 Orleans Street, Baltimore, Maryland 21231, USA.

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http://dx.doi.org/10.1634/stemcells.2005-0598DOI Listing
April 2006

Differences in F36VMpl-based in vivo selection among large animal models.

Mol Ther 2004 Oct;10(4):730-40

Division of Hematology, Department of Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1016/j.ymthe.2004.07.005DOI Listing
October 2004

CD34 cell dose and chronic graft-versus-host disease after human leukocyte antigen-matched sibling hematopoietic stem cell transplantation.

Leuk Lymphoma 2004 Jan;45(1):27-34

Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109-1024, USA.

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http://dx.doi.org/10.1080/1042819031000151103DOI Listing
January 2004

CD34 cell dose and chronic graft-versus-host disease after human leukocyte antigen-matched sibling hematopoietic stem cell transplantation.

Leuk Lymphoma 2004 Jan;45(1):27-34

Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109-1024, USA.

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http://dx.doi.org/10.1080/1042819031000151103DOI Listing
January 2004

Male DNA in female donor apheresis and CD34-enriched products.

Blood 2003 Nov 17;102(10):3845-7. Epub 2003 Jul 17.

Division of Clinical Research, Fred Hutchinson Cancer Research Center, Human Immunogenetics Program, 1100 Fairview Ave N, D2-100, PO Box 19024, Seattle, WA 98109-1024, USA.

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http://dx.doi.org/10.1182/blood-2003-05-1570DOI Listing
November 2003