Sheila Shurtleff

Sheila Shurtleff

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Sheila Shurtleff

Sheila Shurtleff

Publications by authors named "Sheila Shurtleff"

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72Publications

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Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses.

Cancer Cell 2018 09 23;34(3):411-426.e19. Epub 2018 Aug 23.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, MS 323, Memphis, TN 38105-3678, USA; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38105, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158019PMC
September 2018

Gliomatosis cerebri in children shares molecular characteristics with other pediatric gliomas.

Acta Neuropathol 2016 Feb 7;131(2):299-307. Epub 2016 Jan 7.

Department of Pathology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1007/s00401-015-1532-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886851PMC
February 2016

Germline Mutations in Predisposition Genes in Pediatric Cancer.

N Engl J Med 2015 Dec 18;373(24):2336-2346. Epub 2015 Nov 18.

Departments of Computational Biology (J.Z., G.W., M.N.E., D.H., X.M., X.Z., M.R.W., X.C., M.R., A.P., J.B.B., S.W.), Oncology (M.F.W., T.A.G., R.B.M., S.H.-D., R.N., E.Q., A.G., A.S.P., C.-H.P., K.E.N.), and Pathology (T.A.G., M.R.W., S.A.S., D.W.E., C.-H.P., J.R.D.) and the Pediatric Cancer Genome Project (J.Z., M.F.W., G.W., M.N.E., T.A.G., J.E., X.M., D.A.Y., B.V., X.C., R.B.M., S.H.-D., R.N., E.Q., S.A.S., M.R., A.P., J.B.B., S.W., M.S.W., A.G., D.W.E., A.S.P., C.-H.P., K.E.N., J.R.D.), St. Jude Children's Research Hospital, Memphis, TN; and the Department of Genetics and McDonnell Genome Institute, Washington University School of Medicine in St. Louis, St. Louis (L.D., E.R.M., R.K.W.).

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http://dx.doi.org/10.1056/NEJMoa1508054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734119PMC
December 2015

Incidental diagnosis of diffuse intrinsic pontine glioma in children.

Pediatr Blood Cancer 2015 Jun 16;62(6):1081-3. Epub 2015 Jan 16.

Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1002/pbc.25408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405458PMC
June 2015

CONSERTING: integrating copy-number analysis with structural-variation detection.

Nat Methods 2015 Jun 4;12(6):527-30. Epub 2015 May 4.

1] Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. [2] Pediatric Cancer Genome Project, St. Jude Children's Research Hospital and Washington University School of Medicine, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1038/nmeth.3394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591043PMC
June 2015

Genome-wide single-nucleotide polymorphism analysis revealed SUFU suppression of acute graft-versus-host disease through downregulation of HLA-DR expression in recipient dendritic cells.

Sci Rep 2015 Jun 11;5:11098. Epub 2015 Jun 11.

1] Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN [2] Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1038/srep11098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464079PMC
June 2015

Emergence of polyclonal FLT3 tyrosine kinase domain mutations during sequential therapy with sorafenib and sunitinib in FLT3-ITD-positive acute myeloid leukemia.

Clin Cancer Res 2013 Oct 22;19(20):5758-68. Epub 2013 Aug 22.

Authors' Affiliations: Departments of Pharmaceutical Sciences, Structural Biology, Pathology, and Oncology, Hartwell Center for Bioinformatics and Biotechnology, St. Jude Children's Research Hospital; and Department of Pediatrics, University of Tennessee, Memphis, Tennessee.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878304PMC
October 2013

Reference alignment of SNP microarray signals for copy number analysis of tumors.

Bioinformatics 2009 Feb 3;25(3):315-21. Epub 2008 Dec 3.

Department of Biostatistics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btn624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639073PMC
February 2009

Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells.

Cell Stem Cell 2009 Feb;4(2):129-40

Department of Pathology, Stanford University, Stanford, CA 94305, USA; Cancer Research UK Leukaemia Biology Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S193459090800617
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http://dx.doi.org/10.1016/j.stem.2008.11.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670853PMC
February 2009

BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros.

Nature 2008 May 13;453(7191):110-4. Epub 2008 Apr 13.

Department of Pathology, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1038/nature06866DOI Listing
May 2008

A multicenter evaluation of comprehensive analysis of MLL translocations and fusion gene partners in acute leukemia using the MLL FusionChip device.

Cancer Genet Cytogenet 2007 Feb;173(1):17-22

Leukaemia Research Cytogenetics Group, Cancer Sciences Division, University of Southampton, MP 822 Duthie Building, Southampton General Hospital, Southampton SO16 6YD, UK.

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http://dx.doi.org/10.1016/j.cancergencyto.2006.09.006DOI Listing
February 2007

Early molecular detection of central nervous system relapse in a child with systemic anaplastic large cell lymphoma: case report and review of the literature.

Pediatr Blood Cancer 2005 Apr;44(4):400-6

Division of Hematology and Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104-4399, USA.

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http://dx.doi.org/10.1002/pbc.20250DOI Listing
April 2005

Two independent retrotransposon insertions at the same site within the coding region of BTK.

Hum Mutat 2005 Mar;25(3):324-5

Department of Pediatrics, University of Tennessee College of Medicine, Memphis, Tennessee 38105, USA.

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http://doi.wiley.com/10.1002/humu.9321
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http://dx.doi.org/10.1002/humu.9321DOI Listing
March 2005

Genetic analysis of patients with defects in early B-cell development.

Immunol Rev 2005 Feb;203:216-34

Department of Pediatrics, University of Tennessee College of Medicine, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1111/j.0105-2896.2005.00233.xDOI Listing
February 2005

FLT3 inhibition selectively kills childhood acute lymphoblastic leukemia cells with high levels of FLT3 expression.

Blood 2005 Jan 16;105(2):812-20. Epub 2004 Sep 16.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA

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http://dx.doi.org/10.1182/blood-2004-06-2498DOI Listing
January 2005

Gene expression profiling of pediatric acute myelogenous leukemia.

Blood 2004 Dec 29;104(12):3679-87. Epub 2004 Jun 29.

Department of Hematology-Oncology, Hartwell Center for Bioinformatics and Biotechnology, St Jude Children's Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1182/blood-2004-03-1154DOI Listing
December 2004

Reassessment of the prognostic significance of hypodiploidy in pediatric patients with acute lymphoblastic leukemia.

Cancer 2003 Dec;98(12):2715-22

Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105-2794, USA.

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http://dx.doi.org/10.1002/cncr.11841DOI Listing
December 2003

Classification of pediatric acute lymphoblastic leukemia by gene expression profiling.

Blood 2003 Oct 1;102(8):2951-9. Epub 2003 May 1.

Department of Hematology-Oncology, St Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1182/blood-2003-01-0338DOI Listing
October 2003

ALK-positive plasmablastic B-cell lymphoma with expression of the NPM-ALK fusion transcript: report of 2 cases.

Blood 2003 Oct 19;102(7):2642-4. Epub 2003 Jun 19.

Department of Pathology, St Jude Children's Research Hospital, 332 N Lauderdale St, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1182/blood-2003-04-1095DOI Listing
October 2003

A complex variant t(8;21) involving chromosome 3 in a child with acute myeloblastic leukemia with eosinophilia (AML M4Eo).

Leuk Lymphoma 2003 Jan;44(1):183-7

Department of Pathology, St. Jude Children's Research Hospital, 332 North Lauderdale, Memphis, TN 38105-2794, USA.

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http://dx.doi.org/10.1080/1042819031000057289DOI Listing
January 2003

Favorable impact of the t(9;11) in childhood acute myeloid leukemia.

J Clin Oncol 2002 May;20(9):2302-9

Department of Hematology-Oncology, St Jude Children's Research Hospital, Memphis, TN 38105-2794, USA.

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http://dx.doi.org/10.1200/JCO.2002.08.023DOI Listing
May 2002