Sheena McGowan

Sheena McGowan

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Sheena McGowan

Publications by authors named "Sheena McGowan"

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Reply to: Caution is warranted in using cephamycin antibiotics against recurrent Clostridioides difficile infection.

Nat Microbiol 2020 Feb 27;5(2):237-238. Epub 2020 Jan 27.

Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1038/s41564-019-0662-8DOI Listing
February 2020

Strategies for Increasing Protein Stability.

Methods Mol Biol 2020 ;2073:163-181

Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-4939-9869-2_10DOI Listing
January 2020

Cephamycins inhibit pathogen sporulation and effectively treat recurrent Clostridioides difficile infection.

Nat Microbiol 2019 12 12;4(12):2237-2245. Epub 2019 Aug 12.

Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1038/s41564-019-0519-1DOI Listing
December 2019

M17 aminopeptidases diversify function by moderating their macromolecular assemblies and active site environment.

Biochimie 2019 Nov 14;166:38-51. Epub 2019 Jan 14.

Biomedicine Discovery Institute, Department of Microbiology, Monash University, Melbourne, VIC, 3800, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.biochi.2019.01.007DOI Listing
November 2019

Novel Human Aminopeptidase N Inhibitors: Discovery and Optimization of Subsite Binding Interactions.

J Med Chem 2019 Aug 18;62(15):7185-7209. Epub 2019 Jul 18.

Infection and Immunity Program, Biomedicine Discovery Institute and Department of Microbiology , Monash University , Clayton Campus , Clayton , VIC 3800 , Australia.

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http://dx.doi.org/10.1021/acs.jmedchem.9b00757DOI Listing
August 2019

Crystal structure of the inhibitor-free form of the serine protease kallikrein-4.

Acta Crystallogr F Struct Biol Commun 2019 Aug 16;75(Pt 8):543-546. Epub 2019 Jul 16.

Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, 23 Innovation Walk, Clayton, VIC 3800, Australia.

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http://dx.doi.org/10.1107/S2053230X19009610DOI Listing
August 2019

Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe.

ChemMedChem 2019 03 13;14(5):603-612. Epub 2019 Feb 13.

Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, 3052, Australia.

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http://doi.wiley.com/10.1002/cmdc.201800802
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http://dx.doi.org/10.1002/cmdc.201800802DOI Listing
March 2019

Reactive centre loop dynamics and serpin specificity.

Sci Rep 2019 03 7;9(1):3870. Epub 2019 Mar 7.

Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Victoria, 3800, Australia.

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http://dx.doi.org/10.1038/s41598-019-40432-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405850PMC
March 2019

Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases.

J Med Chem 2019 01 4;62(2):622-640. Epub 2019 Jan 4.

Department of Microbiology, Biomedicine Discovery Institute , Monash University, Clayton , Melbourne , VIC 3800 , Australia.

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http://dx.doi.org/10.1021/acs.jmedchem.8b01310DOI Listing
January 2019

Catalytic diversity and cell wall binding repeats in the phage-encoded endolysins.

Mol Microbiol 2018 12 13;110(6):879-896. Epub 2018 Nov 13.

Biomedicine Discovery Institute, Department of Microbiology, Monash University, Victoria, 3800, Australia.

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http://dx.doi.org/10.1111/mmi.14134DOI Listing
December 2018

Mapping the Pathway and Dynamics of Bestatin Inhibition of the Plasmodium falciparum M1 Aminopeptidase PfA-M1.

ChemMedChem 2018 12 9;13(23):2504-2513. Epub 2018 Nov 9.

Infection and Immunity Program, Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, 3800, Australia.

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http://dx.doi.org/10.1002/cmdc.201800563DOI Listing
December 2018

Generation of AMBER force field parameters for zinc centres of M1 and M17 family aminopeptidases.

J Biomol Struct Dyn 2018 Aug 28;36(10):2595-2604. Epub 2017 Aug 28.

a Infection and Immunity Program, Department of Microbiology, Biomedicine Discovery Institute , Monash University , Clayton , Victoria 3800 , Australia.

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http://dx.doi.org/10.1080/07391102.2017.1364669DOI Listing
August 2018

Clostridium sordellii outer spore proteins maintain spore structural integrity and promote bacterial clearance from the gastrointestinal tract.

PLoS Pathog 2018 04 18;14(4):e1007004. Epub 2018 Apr 18.

Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1371/journal.ppat.1007004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927469PMC
April 2018

Crystal structure of a β-aminopeptidase from an Australian Burkholderia sp.

Acta Crystallogr F Struct Biol Commun 2017 07 17;73(Pt 7):386-392. Epub 2017 Jun 17.

Biomedicine Discovery Institute, Department of Microbiology, Monash University, Clayton, Melbourne, VIC 3800, Australia.

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http://dx.doi.org/10.1107/S2053230X17007737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505242PMC
July 2017

X-ray crystal structure of cytochrome P450 monooxygenase CYP101J2 from Sphingobium yanoikuyae strain B2.

Proteins 2017 05 3;85(5):945-950. Epub 2017 Mar 3.

Infection and Immunity Program, Biomedicine Discovery Institute, Department of Microbiology, Monash University, Clayton, Victoria, 3800.

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http://dx.doi.org/10.1002/prot.25227DOI Listing
May 2017

M1 aminopeptidases as drug targets: broad applications or therapeutic niche?

FEBS J 2017 05 3;284(10):1473-1488. Epub 2017 Feb 3.

Biomedicine Discovery Institute, Department of Microbiology, Monash University, Melbourne, Vic., Australia.

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http://dx.doi.org/10.1111/febs.14009DOI Listing
May 2017

Circumventing the stability-function trade-off in an engineered FN3 domain.

Protein Eng Des Sel 2016 Nov;29(11):541-550

Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.

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http://dx.doi.org/10.1093/protein/gzw046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081044PMC
November 2016

Structure-Activity Studies of β-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.

J Mol Biol 2016 10 14;428(20):3986-3998. Epub 2016 Jul 14.

Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria 3052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2016.07.001DOI Listing
October 2016

Structure and substrate fingerprint of aminopeptidase P from Plasmodium falciparum.

Biochem J 2016 10 26;473(19):3189-204. Epub 2016 Jul 26.

Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton Campus, Melbourne, VIC 3800, Australia.

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http://dx.doi.org/10.1042/BCJ20160550DOI Listing
October 2016

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Authors:
Wesley C Van Voorhis John H Adams Roberto Adelfio Vida Ahyong Myles H Akabas Pietro Alano Aintzane Alday Yesmalie Alemán Resto Aishah Alsibaee Ainhoa Alzualde Katherine T Andrews Simon V Avery Vicky M Avery Lawrence Ayong Mark Baker Stephen Baker Choukri Ben Mamoun Sangeeta Bhatia Quentin Bickle Lotfi Bounaadja Tana Bowling Jürgen Bosch Lauren E Boucher Fabrice F Boyom Jose Brea Marian Brennan Audrey Burton Conor R Caffrey Grazia Camarda Manuela Carrasquilla Dee Carter Maria Belen Cassera Ken Chih-Chien Cheng Worathad Chindaudomsate Anthony Chubb Beatrice L Colon Daisy D Colón-López Yolanda Corbett Gregory J Crowther Noemi Cowan Sarah D'Alessandro Na Le Dang Michael Delves Joseph L DeRisi Alan Y Du Sandra Duffy Shimaa Abd El-Salam El-Sayed Michael T Ferdig José A Fernández Robledo David A Fidock Isabelle Florent Patrick V T Fokou Ani Galstian Francisco Javier Gamo Suzanne Gokool Ben Gold Todd Golub Gregory M Goldgof Rajarshi Guha W Armand Guiguemde Nil Gural R Kiplin Guy Michael A E Hansen Kirsten K Hanson Andrew Hemphill Rob Hooft van Huijsduijnen Takaaki Horii Paul Horrocks Tyler B Hughes Christopher Huston Ikuo Igarashi Katrin Ingram-Sieber Maurice A Itoe Ajit Jadhav Amornrat Naranuntarat Jensen Laran T Jensen Rays H Y Jiang Annette Kaiser Jennifer Keiser Thomas Ketas Sebastien Kicka Sunyoung Kim Kiaran Kirk Vidya P Kumar Dennis E Kyle Maria Jose Lafuente Scott Landfear Nathan Lee Sukjun Lee Adele M Lehane Fengwu Li David Little Liqiong Liu Manuel Llinás Maria I Loza Aristea Lubar Leonardo Lucantoni Isabelle Lucet Louis Maes Dalu Mancama Nuha R Mansour Sandra March Sheena McGowan Iset Medina Vera Stephan Meister Luke Mercer Jordi Mestres Alvine N Mfopa Raj N Misra Seunghyun Moon John P Moore Francielly Morais Rodrigues da Costa Joachim Müller Arantza Muriana Stephen Nakazawa Hewitt Bakela Nare Carl Nathan Nathalie Narraidoo Sujeevi Nawaratna Kayode K Ojo Diana Ortiz Gordana Panic George Papadatos Silvia Parapini Kailash Patra Ngoc Pham Sarah Prats David M Plouffe Sally-Ann Poulsen Anupam Pradhan Celia Quevedo Ronald J Quinn Christopher A Rice Mohamed Abdo Rizk Andrea Ruecker Robert St Onge Rafaela Salgado Ferreira Jasmeet Samra Natalie G Robinett Ulrich Schlecht Marjorie Schmitt Filipe Silva Villela Francesco Silvestrini Robert Sinden Dennis A Smith Thierry Soldati Andreas Spitzmüller Serge Maximilian Stamm David J Sullivan William Sullivan Sundari Suresh Brian M Suzuki Yo Suzuki S Joshua Swamidass Donatella Taramelli Lauve R Y Tchokouaha Anjo Theron David Thomas Kathryn F Tonissen Simon Townson Abhai K Tripathi Valentin Trofimov Kenneth O Udenze Imran Ullah Cindy Vallieres Edgar Vigil Joseph M Vinetz Phat Voong Vinh Hoan Vu Nao-Aki Watanabe Kate Weatherby Pamela M White Andrew F Wilks Elizabeth A Winzeler Edward Wojcik Melanie Wree Wesley Wu Naoaki Yokoyama Paul H A Zollo Nada Abla Benjamin Blasco Jeremy Burrows Benoît Laleu Didier Leroy Thomas Spangenberg Timothy Wells Paul A Willis

PLoS Pathog 2016 07 28;12(7):e1005763. Epub 2016 Jul 28.

Medicines for Malaria Venture, Geneva, Switzerland.

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http://dx.doi.org/10.1371/journal.ppat.1005763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965013PMC
July 2016

Dynamic Motion and Communication in the Streptococcal C1 Phage Lysin, PlyC.

PLoS One 2015 15;10(10):e0140219. Epub 2015 Oct 15.

Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia; Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140219PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607406PMC
June 2016

Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.

Eur J Med Chem 2016 Mar 13;110:43-64. Epub 2016 Jan 13.

Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville Campus), Parkville, VIC 3052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2016.01.015DOI Listing
March 2016

Stonefish toxin defines an ancient branch of the perforin-like superfamily.

Proc Natl Acad Sci U S A 2015 Dec 1;112(50):15360-5. Epub 2015 Dec 1.

Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, VIC, 3800, Australia;

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http://dx.doi.org/10.1073/pnas.1507622112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687532PMC
December 2015

Oxidative Deselenization of Selenocysteine: Applications for Programmed Ligation at Serine.

Angew Chem Int Ed Engl 2015 Oct 1;54(43):12716-21. Epub 2015 Sep 1.

School of Chemistry, The University of Sydney, NSW 2006 (Australia) http://sydney.edu.au/science/chemistry/∼payne/index.html.

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http://dx.doi.org/10.1002/anie.201504639DOI Listing
October 2015

Molecular insights into the interaction between Plasmodium falciparum apical membrane antigen 1 and an invasion-inhibitory peptide.

PLoS One 2014 24;9(10):e109674. Epub 2014 Oct 24.

Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia; Australian Research Council Centre of Excellence for Coherent X-ray Science, Monash University, Parkville, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0109674PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208761PMC
June 2015

X-ray crystal structures of an orally available aminopeptidase inhibitor, Tosedostat, bound to anti-malarial drug targets PfA-M1 and PfA-M17.

Proteins 2015 Apr 28;83(4):789-95. Epub 2015 Feb 28.

Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria, 3800, Australia.

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http://dx.doi.org/10.1002/prot.24771DOI Listing
April 2015

Screening for hypothyroidism in Down syndrome using the capillary thyroid stimulating hormone method.

J Pediatr 2015 Apr 31;166(4):1013-1017.e2. Epub 2015 Jan 31.

Section of Child Health, Royal Hospital for Sick Children, University of Glasgow School of Medicine, Yorkhill, Glasgow, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2014.12.035DOI Listing
April 2015

Structural and dynamic properties that govern the stability of an engineered fibronectin type III domain.

Protein Eng Des Sel 2015 Mar;28(3):67-78

Department of Biochemistry and Molecular Biology, Faculty of Medicine, School of Biomedical Sciences, Monash University, Clayton, VIC 3800, Australia

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http://dx.doi.org/10.1093/protein/gzv002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330816PMC
March 2015

Identification of the molecular basis of inhibitor selectivity between the human and streptococcal type I methionine aminopeptidases.

J Med Chem 2015 Mar 27;58(5):2350-7. Epub 2015 Feb 27.

Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology , Hyderabad 500 007, India.

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http://pubs.acs.org/doi/10.1021/jm501790e
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http://dx.doi.org/10.1021/jm501790eDOI Listing
March 2015

Short Stature Screening by Accurate Length Measurement in Infants with a Birth Weight <9th Centile.

Horm Res Paediatr 2015 Mar 31. Epub 2015 Mar 31.

Department of Child Health, University of Glasgow School of Medicine, Royal Hospital for Sick Children, Glasgow, UK.

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http://dx.doi.org/10.1159/000376611DOI Listing
March 2015

Synthesis of gallinamide A analogues as potent falcipain inhibitors and antimalarials.

J Med Chem 2014 Dec 8;57(24):10557-63. Epub 2014 Dec 8.

School of Chemistry, The University of Sydney , Building F11, Sydney, New South Wales 2006, Australia.

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http://dx.doi.org/10.1021/jm501439wDOI Listing
December 2014

Two-pronged attack: dual inhibition of Plasmodium falciparum M1 and M17 metalloaminopeptidases by a novel series of hydroxamic acid-based inhibitors.

J Med Chem 2014 Nov 24;57(21):9168-83. Epub 2014 Oct 24.

Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University , Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1021/jm501323aDOI Listing
November 2014

Structure and dynamics of apical membrane antigen 1 from Plasmodium falciparum FVO.

Biochemistry 2014 Nov 14;53(46):7310-20. Epub 2014 Nov 14.

Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University , Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1021/bi5012089DOI Listing
November 2014

Operation of the Australian Store.Synchrotron for macromolecular crystallography.

Acta Crystallogr D Biol Crystallogr 2014 Oct 30;70(Pt 10):2510-9. Epub 2014 Sep 30.

Monash Bioinformatics Platform, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1107/S1399004714016174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187999PMC
October 2014

From crystal to compound: structure-based antimalarial drug discovery.

Biochem J 2014 Aug;461(3):349-69

*Department of Biochemistry and Molecular Biology, Monash University, Clayton Campus, Melbourne, VIC 3800, Australia.

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http://dx.doi.org/10.1042/BJ20140240DOI Listing
August 2014

Aminopeptidase N1 (EtAPN1), an M1 metalloprotease of the apicomplexan parasite Eimeria tenella, participates in parasite development.

Eukaryot Cell 2014 Jul 16;13(7):884-95. Epub 2014 May 16.

INRA, UMR 1282, Infectiologie et Santé Publique, Nouzilly, France Université François Rabelais de Tours, UMR 1282, Infectiologie et Santé Publique, Tours, France.

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http://dx.doi.org/10.1128/EC.00062-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135734PMC
July 2014

Working in concert: the metalloaminopeptidases from Plasmodium falciparum.

Authors:
Sheena McGowan

Curr Opin Struct Biol 2013 Dec 13;23(6):828-35. Epub 2013 Aug 13.

Department of Biochemistry and Molecular Biology, Monash University, Clayton Campus, Melbourne, Victoria 3800, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.sbi.2013.07.015DOI Listing
December 2013

Sitagliptin does not inhibit the M1 alanyl aminopeptidase from Plasmodium falciparum.

Authors:
Sheena McGowan

Bioinformation 2013 17;9(13):661-2. Epub 2013 Jul 17.

Department of Biochemistry and Molecular Biology, Monash University, Clayton Campus, Australia.

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http://dx.doi.org/10.6026/97320630009661DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732437PMC
August 2013

Synthesis and structure-activity relationships of phosphonic arginine mimetics as inhibitors of the M1 and M17 aminopeptidases from Plasmodium falciparum.

J Med Chem 2013 Jun 13;56(12):5213-7. Epub 2013 Jun 13.

Department of Biochemistry and Molecular Biology, Monash University, Clayton Campus, Melbourne, VIC 3800, Australia.

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http://dx.doi.org/10.1021/jm4005972DOI Listing
June 2013

X-ray crystal structure and specificity of the Plasmodium falciparum malaria aminopeptidase PfM18AAP.

J Mol Biol 2012 Sep 16;422(4):495-507. Epub 2012 Jun 16.

Department of Biochemistry and Molecular Biology, Monash University, Clayton Campus, Melbourne, VIC 3800, Australia.

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http://dx.doi.org/10.1016/j.jmb.2012.06.006DOI Listing
September 2012

X-ray crystal structure of the streptococcal specific phage lysin PlyC.

Proc Natl Acad Sci U S A 2012 Jul 17;109(31):12752-7. Epub 2012 Jul 17.

Department of Biochemistry and Molecular Biology, Monash University, Clayton 3800, Australia.

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http://dx.doi.org/10.1073/pnas.1208424109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412044PMC
July 2012

Isolation and characterization of the nuclear serpin MENT.

Methods Enzymol 2011 ;501:29-47

Department of Biochemistry & Molecular Biology, Penn State University College of Medicine, Milton S. Hershey Medical Center, University Drive, Hershey, Pennsylvania, USA.

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http://dx.doi.org/10.1016/B978-0-12-385950-1.00003-1DOI Listing
March 2012

Capillary TSH screening programme for Down's syndrome in Scotland, 1997-2009.

Arch Dis Child 2011 Dec 30;96(12):1113-7. Epub 2011 Sep 30.

Department of Child Health, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK.

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http://dx.doi.org/10.1136/archdischild-2011-300124DOI Listing
December 2011

Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases.

Proc Natl Acad Sci U S A 2011 Aug 15;108(34):E526-34. Epub 2011 Aug 15.

Department of Pharmacology, University of Pennsylvania, 433 South University Avenue, 304G Lynch Laboratories, Philadelphia, PA 19104-6018, USA.

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http://dx.doi.org/10.1073/pnas.1105601108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161592PMC
August 2011

Synthesis of new (-)-bestatin-based inhibitor libraries reveals a novel binding mode in the S1 pocket of the essential malaria M1 metalloaminopeptidase.

J Med Chem 2011 Mar 2;54(6):1655-66. Epub 2011 Mar 2.

Department of Pharmacology, University of Pennsylvania, 433 South University Avenue, 304G Lynch Laboratories, Philadelphia, Pennsylvania 19104-6018, United States.

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http://dx.doi.org/10.1021/jm101227tDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516848PMC
March 2011

A pharmacological and biochemical examination of the geographical variation of Chironex fleckeri venom.

Toxicol Lett 2010 Feb 27;192(3):419-24. Epub 2009 Nov 27.

Department of Pharmacology, Monash University, Victoria, Australia.

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http://dx.doi.org/10.1016/j.toxlet.2009.11.019DOI Listing
February 2010

Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials.

Trends Biochem Sci 2010 Jan 30;35(1):53-61. Epub 2009 Sep 30.

Malaria Biology Laboratory, Queensland Institute of Medical Research, Herston, QLD 4006, Australia.

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http://dx.doi.org/10.1016/j.tibs.2009.08.004DOI Listing
January 2010

Functional analysis of the VirSR phosphorelay from Clostridium perfringens.

PLoS One 2009 Jun 9;4(6):e5849. Epub 2009 Jun 9.

Department of Microbiology, Monash University, Clayton, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005849PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688746PMC
June 2009

Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase.

Proc Natl Acad Sci U S A 2009 Feb 5;106(8):2537-42. Epub 2009 Feb 5.

Department of Biochemistry and Molecular Biology and Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, Monash University, Clayton, Victoria, 3800, Australia.

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http://dx.doi.org/10.1073/pnas.0807398106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636733PMC
February 2009

Federated repositories of X-ray diffraction images.

Acta Crystallogr D Biol Crystallogr 2008 Jul 18;D64(Pt 7):810-4. Epub 2008 Jun 18.

The Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Faculty of Medicine, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1107/S0907444908015540DOI Listing
July 2008

DNA accelerates the inhibition of human cathepsin V by serpins.

J Biol Chem 2007 Dec 8;282(51):36980-6. Epub 2007 Oct 8.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M706991200
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http://dx.doi.org/10.1074/jbc.M706991200DOI Listing
December 2007

The 1.6 A crystal structure of the catalytic domain of PlyB, a bacteriophage lysin active against Bacillus anthracis.

J Mol Biol 2007 Feb 18;366(2):540-50. Epub 2006 Nov 18.

Protein Crystallography Unit, Department of Biochemistry and Molecular Biology and The ARC Centre of Excellence for Structural and Functional Microbial Genomics, Monash University, Clayton, Melbourne, VIC 3800, Australia.

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http://dx.doi.org/10.1016/j.jmb.2006.11.056DOI Listing
February 2007

An overview of the serpin superfamily.

Genome Biol 2006 30;7(5):216. Epub 2006 May 30.

Department of Biochemistry and Molecular Biology, Monash University, Clayton Campus, Melbourne VIC 3800, Australia.

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http://dx.doi.org/10.1186/gb-2006-7-5-216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779521PMC
August 2006

The SKHR motif is required for biological function of the VirR response regulator from Clostridium perfringens.

J Bacteriol 2003 Oct;185(20):6205-8

Bacterial Pathogenesis Research Group, Department of Microbiology, Monash University, Victoria 3800, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC225049PMC
http://dx.doi.org/10.1128/jb.185.20.6205-6208.2003DOI Listing
October 2003

The FxRxHrS motif: a conserved region essential for DNA binding of the VirR response regulator from Clostridium perfringens.

J Mol Biol 2002 Oct;322(5):997-1011

Bacterial Pathogenesis Research Group, Department of Microbiology, Monash University, 3800 Australia.

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http://dx.doi.org/10.1016/s0022-2836(02)00850-1DOI Listing
October 2002