Shawn M Gomez

Shawn M Gomez

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Shawn M Gomez

Shawn M Gomez

Publications by authors named "Shawn M Gomez"

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Recombination drives the evolution of mutational robustness.

Curr Opin Syst Biol 2019 Feb 2;13:142-149. Epub 2019 Jan 2.

Biology Department, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1016/j.coisb.2018.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768415PMC
February 2019

Coral: Clear and Customizable Visualization of Human Kinome Data.

Cell Syst 2018 09 29;7(3):347-350.e1. Epub 2018 Aug 29.

Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC 27599, USA; Department of Cell Biology & Physiology, University of North Carolina, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2018.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366324PMC
September 2018

Spatiotemporal organization of exocytosis emerges during neuronal shape change.

J Cell Biol 2018 03 19;217(3):1113-1128. Epub 2018 Jan 19.

Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC

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http://dx.doi.org/10.1083/jcb.201709064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839795PMC
March 2018

MAP3K4 Controls the Chromatin Modifier HDAC6 during Trophoblast Stem Cell Epithelial-to-Mesenchymal Transition.

Cell Rep 2017 03;18(10):2387-2400

Department of Biological Sciences, University of Memphis, Memphis, TN 38152, USA; Department of Biomedical Engineering, University of Memphis, Memphis, TN 38152, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.02.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496714PMC
March 2017

Two functionally distinct sources of actin monomers supply the leading edge of lamellipodia.

Cell Rep 2015 Apr 10;11(3):433-45. Epub 2015 Apr 10.

Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA; Center for Neurodegenerative Diseases, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.03.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418508PMC
April 2015

Transcriptome-wide identification and study of cancer-specific splicing events across multiple tumors.

Oncotarget 2015 Mar;6(9):6825-39

Curriculum in Bioinformatics and Computational Biology, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466652PMC
http://dx.doi.org/10.18632/oncotarget.3145DOI Listing
March 2015

LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues.

J Cell Biol 2014 Oct;207(2):299-315

University of North Carolina Lineberger Comprehensive Cancer Center, Department of Cell Biology and Physiology, Department of Genetics, Department of Biomedical Engineering, Carolina Center for Genome Science, Department of Pediatrics, and Howard Hughes Medical Institute, University of North Carolina-Chapel Hill, Chapel Hill, NC 27599 University of North Carolina Lineberger Comprehensive Cancer Center, Department of Cell Biology and Physiology, Department of Genetics, Department of Biomedical Engineering, Carolina Center for Genome Science, Department of Pediatrics, and Howard Hughes Medical Institute, University of North Carolina-Chapel Hill, Chapel Hill, NC 27599 University of North Carolina Lineberger Comprehensive Cancer Center, Department of Cell Biology and Physiology, Department of Genetics, Department of Biomedical Engineering, Carolina Center for Genome Science, Department of Pediatrics, and Howard Hughes Medical Institute, University of North Carolina-Chapel Hill, Chapel Hill, NC 27599

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http://dx.doi.org/10.1083/jcb.201404067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210439PMC
October 2014

Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms.

Proc Natl Acad Sci U S A 2014 Aug 12;111(34):12420-5. Epub 2014 Aug 12.

Department of Pharmacology, Lineberger Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599

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http://dx.doi.org/10.1073/pnas.1404487111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151743PMC
August 2014

Automated analysis of invadopodia dynamics in live cells.

PeerJ 2014 1;2:e462. Epub 2014 Jul 1.

UNC/NCSU Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill , Chapel Hill, NC , USA ; Department of Computer Science, University of North Carolina at Chapel Hill , Chapel Hill, NC , USA ; Department of Pharmacology, University of North Carolina at Chapel Hill , Chapel Hill, NC , USA.

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http://dx.doi.org/10.7717/peerj.462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103095PMC
July 2014

The Focal Adhesion Analysis Server: a web tool for analyzing focal adhesion dynamics.

F1000Res 2013 4;2:68. Epub 2013 Mar 4.

UNC/NCSU Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7575, USA ; UNC Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7575, USA ; UNC Department of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7575, USA.

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http://dx.doi.org/10.12688/f1000research.2-68.v1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752736PMC
December 2013

Nck enables directional cell migration through the coordination of polarized membrane protrusion with adhesion dynamics.

J Cell Sci 2013 Apr 26;126(Pt 7):1637-49. Epub 2013 Feb 26.

Department of Veterinary Pathobiology, Texas A&M University, College Station, TX 77843-4467, USA.

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http://dx.doi.org/10.1242/jcs.119610DOI Listing
April 2013

Defining the expressed breast cancer kinome.

Cell Res 2012 Apr 7;22(4):620-3. Epub 2012 Feb 7.

Biomedical Engineering and Curriculum in Bioinformatics and Computational Biology, Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1038/cr.2012.25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317564PMC
April 2012

A whole-body model for glycogen regulation reveals a critical role for substrate cycling in maintaining blood glucose homeostasis.

PLoS Comput Biol 2011 Dec 1;7(12):e1002272. Epub 2011 Dec 1.

Department of Biomedical Engineering, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1002272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233304PMC
December 2011

High-resolution quantification of focal adhesion spatiotemporal dynamics in living cells.

PLoS One 2011 14;6(7):e22025. Epub 2011 Jul 14.

Department of Biomedical Engineering, University of North Carolina, Chapel Hill, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0022025PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136503PMC
November 2011

Mapping protein interactions between Dengue virus and its human and insect hosts.

PLoS Negl Trop Dis 2011 Feb 15;5(2):e954. Epub 2011 Feb 15.

Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0000954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039688PMC
February 2011

Structural similarity-based predictions of protein interactions between HIV-1 and Homo sapiens.

Virol J 2010 Apr 28;7:82. Epub 2010 Apr 28.

Department of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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http://virologyj.biomedcentral.com/articles/10.1186/1743-422
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http://dx.doi.org/10.1186/1743-422X-7-82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877021PMC
April 2010

Enhancing metabolomic data analysis with Progressive Consensus Alignment of NMR Spectra (PCANS).

BMC Bioinformatics 2010 Mar 9;11:123. Epub 2010 Mar 9.

Department of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1186/1471-2105-11-123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851603PMC
March 2010

Comparison of phylogenetic trees through alignment of embedded evolutionary distances.

BMC Bioinformatics 2009 Dec 15;10:423. Epub 2009 Dec 15.

Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1186/1471-2105-10-423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087345PMC
December 2009

Sequence patches on MAPK surfaces define protein-protein interactions.

Genome Biol 2009 5;10(6):222. Epub 2009 Jun 5.

Department of Pharmacology and Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599-7365, USA.

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http://dx.doi.org/10.1186/gb-2009-10-6-222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718487PMC
September 2009

Prediction of protein-protein interaction networks.

Curr Protoc Bioinformatics 2008 Jun;Chapter 8:Unit 8.2

Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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http://doi.wiley.com/10.1002/0471250953.bi0802s22
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http://dx.doi.org/10.1002/0471250953.bi0802s22DOI Listing
June 2008

Data-driven modeling of cellular stimulation, signaling and output response in RAW 264.7 cells.

J Mol Signal 2008 May 22;3:11. Epub 2008 May 22.

Joint Department of Biomedical Engineering, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1186/1750-2187-3-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441624PMC
May 2008

SAGE analysis of mosquito salivary gland transcriptomes during Plasmodium invasion.

Cell Microbiol 2007 Mar 18;9(3):708-24. Epub 2006 Oct 18.

Unité de Biochimie et Biologie Moléculaire des Insectes, Institut Pasteur, 28 rue du Dr Roux, 75724, Paris, France.

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http://dx.doi.org/10.1111/j.1462-5822.2006.00822.xDOI Listing
March 2007

Pilot Anopheles gambiae full-length cDNA study: sequencing and initial characterization of 35,575 clones.

Genome Biol 2005 15;6(4):R39. Epub 2005 Mar 15.

Unité de Biochimie et Biologie Moléculaire des Insectes and CNRS FRE 2849, Institut Pasteur, 75724 Paris Cedex 15, France.

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http://dx.doi.org/10.1186/gb-2005-6-4-r39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1088967PMC
August 2006

Of truth and pathways: chasing bits of information through myriads of articles.

Bioinformatics 2002 ;18 Suppl 1:S249-57

Department of Medical Informatics, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1093/bioinformatics/18.suppl_1.s249DOI Listing
October 2004

Learning to predict protein-protein interactions from protein sequences.

Bioinformatics 2003 Oct;19(15):1875-81

Unité de Biochimie et Biologie Moléculaire des Insectes, Institut Pasteur, 75724 Paris Cedex 15, France.

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http://dx.doi.org/10.1093/bioinformatics/btg352DOI Listing
October 2003

Prediction of protein-protein interaction networks.

Authors:
Shawn M Gomez

Curr Protoc Bioinformatics 2003 May;Chapter 8:Unit8.2

Unité de Biochimie et Biologie Moléculaire des Insectes Institut Pasteur, Paris, France.

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http://doi.wiley.com/10.1002/0471250953.bi0802s01
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http://dx.doi.org/10.1002/0471250953.bi0802s01DOI Listing
May 2003

Network approaches to genome annotation and the challenge of Anopheles gambiae.

Authors:
Shawn M Gomez

Mol Cells 2003 Apr;15(2):159-63

Unité de Biochimie et Biologie Moléculaire des Insectes, Institut Pasteur, 28 rue du Dr. Roux, 75724 Paris Cedex 15, France.

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April 2003

Towards the prediction of complete protein--protein interaction networks.

Pac Symp Biocomput 2002 :413-24

Columbia Genome Center, Columbia University, 1150 St. Nicholas Avenue, Unit 109, New York, NY 10032, USA.

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October 2002