Publications by authors named "Shashit Shetty Bavabeedu"

2 Publications

  • Page 1 of 1

Synergistic Effect of Plant Extracts on Endodontic Pathogens Isolated from Teeth with Root Canal Treatment Failure: An In Vitro Study.

Antibiotics (Basel) 2021 May 9;10(5). Epub 2021 May 9.

Department of Restorative Dental Sciences, College of Dentistry, King Khalid University, Abha 61321, Saudi Arabia.

Background And Objectives: This study aimed to evaluate the synergistic antimicrobial activity of extracts obtained from (Miswak), (myrrh) and (neem) in combination with commercially available antimicrobial agents: penicillin, tetracycline, ofloxacin and fluconazole on endodontic pathogens such as and .

Materials And Methods: Microbiological samples from the root canals of the teeth undergoing retreatment were taken using sterile paper points kept at full length in the canal for 30 s. The disc diffusion method was used to check the susceptibility of microbes to the plant extracts and antimicrobials by measuring the diameter of the inhibition zones. Against the microbes, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC)/minimum fungicidal concentration (MFC) of the plant extracts were assessed. The fractional inhibitory concentration index (FICI) was used to estimate the synergistic effect of plant extracts combined with antimicrobials against the resistant endodontic microbes.

Results: The findings clearly indicate the effectiveness of all the three plant extracts, against all the experimental pathogenic microorganisms except for the ineffectiveness of against Maximum antimicrobial activity was displayed by against (MIC = 0.09 ± 1.2 mg/mL, MBC = 0.78 ± 1.25 mg/mL) and the minimum antimicrobial activity was displayed by against (MIC = 12.5 ± 3.25 mg/mL, MBC = 100 ± 3.75 mg/mL). The best synergy was displayed by with fluconazole against (FICI = 0.45).

Conclusions: The current study delineates the variable antimicrobial activity of plant extracts against the experimental endodontic pathogenic microorganisms. Plant extracts in conjunction with various antimicrobials can be valuable aids in combating relatively resistant endodontic microorganisms that have been the cause of worry in recent years, leading to failure even in treatment procedures following all required protocols.
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http://dx.doi.org/10.3390/antibiotics10050552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151008PMC
May 2021

Effect of Fluoride Concentration in Drinking Water on Dental Fluorosis in Southwest Saudi Arabia.

Int J Environ Res Public Health 2020 06 1;17(11). Epub 2020 Jun 1.

Department of Public Health Dentistry, Kothiwal Dental College and Research Center, Moradabad 244001, UP, India.

This study was intended to evaluate the fluoride concentration in drinking water and its effect on dental fluorosis in Southwest Saudi Arabia. Water samples were gathered rom wells, filtration plants and commercial brands (bottled water) in distinct urban and rural areas of Asir region of the Kingdom of Saudi Arabia (KSA). Overall, 63 water samples were collected from 12 locations and 9 brands of bottled water. ExStik FL700Fluoridemeter was used in the analysis of water samples for fluoride levels. The total number of screened patients for dental fluorosis, aged between 9 and 50 years, was 1150; among them, 609 were males and 541 were females. Dean's index criteria were used to examine the patients for dental fluorosis. The results revealed that fluoride levels varied between 0.03 and 3.8 ppm. People who drank well water displayed increased fluoride levels (>0.81 ppm). The prevalence of dental fluorosis was established to be 20.43% among the total number of examined patients. The findings of this study show very mild to moderate dental fluorosis prevail among the patients who consume well water in the Asir region.
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http://dx.doi.org/10.3390/ijerph17113914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312808PMC
June 2020
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