Sharyn Baker

Sharyn Baker

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Interaction Between Sex and Organic Anion-Transporting Polypeptide 1b2 on the Pharmacokinetics of Regorafenib and Its Metabolites Regorafenib-N-Oxide and Regorafenib-Glucuronide in Mice.

Clin Transl Sci 2019 Jul 6;12(4):400-407. Epub 2019 Apr 6.

Division of Pharmaceutics and Pharmaceutical Chemistry and Comprehensive Cancer Center, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/cts.12630
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http://dx.doi.org/10.1111/cts.12630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662550PMC
July 2019

Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1.

Clin Pharmacol Ther 2019 Jul 27. Epub 2019 Jul 27.

Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.

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http://dx.doi.org/10.1002/cpt.1588DOI Listing
July 2019

Hypoxia Reporter Element Assay.

Bio Protoc 2018 Aug;8(15)

Division of Pharmaceutics, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA.

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http://dx.doi.org/10.21769/BioProtoc.2951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424511PMC
August 2018

Development and validation of an analytical method for regorafenib and its metabolites in mouse plasma.

J Chromatogr B Analyt Technol Biomed Life Sci 2018 Jul 5;1090:43-51. Epub 2018 May 5.

Division of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The Ohio State University, Columbus, OH, USA; Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1016/j.jchromb.2018.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991487PMC
July 2018

Kinase Inhibitors: The Reality Behind the Success.

Clin Pharmacol Ther 2017 Nov;102(5):726-730

Division of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy and Comprehensive Cancer Center, Ohio State University, Columbus, Ohio, USA.

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http://dx.doi.org/10.1002/cpt.815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069597PMC
November 2017

Discovery of a Diaminopyrimidine FLT3 Inhibitor Active against Acute Myeloid Leukemia.

ACS Omega 2017 May 10;2(5):1985-2009. Epub 2017 May 10.

Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, United States.

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http://dx.doi.org/10.1021/acsomega.7b00144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452050PMC
May 2017

Design, synthesis and evaluation of anti-CD123 antibody drug conjugates.

Bioorg Med Chem 2016 11 17;24(22):5855-5860. Epub 2016 Sep 17.

Division of Pharmaceutics & Pharmaceutical Chemistry, College of Pharmacy, The Ohio State University, Columbus, OH 43210, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2016.09.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318162PMC
November 2016

Evaluation of artemisinins for the treatment of acute myeloid leukemia.

Cancer Chemother Pharmacol 2016 06 28;77(6):1231-43. Epub 2016 Apr 28.

Division of Pharmaceutics, College of Pharmacy, The Ohio State University, 500 W. 12th St., Columbus, OH, 43210, USA.

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http://dx.doi.org/10.1007/s00280-016-3038-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918815PMC
June 2016

Sorafenib metabolism, transport, and enterohepatic recycling: physiologically based modeling and simulation in mice.

Cancer Chemother Pharmacol 2016 05 6;77(5):1039-52. Epub 2016 Apr 6.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1007/s00280-016-3018-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846505PMC
May 2016

Corrigendum to "Quantification of 5-azacytidine in plasma by electrospray tandem mass spectrometry coupled with high-performance liquid chromatography" [J. Chromatogr. B 813(1) (2004) 81-88].

J Chromatogr B Analyt Technol Biomed Life Sci 2016 May 25;1020:167. Epub 2016 Mar 25.

Division of Experimental Therapeutics, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Bunting-Blaustein Cancer Research Building, 1650 Orleans Street, Room 1M87, Baltimore, MD 21231, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2016.03.018DOI Listing
May 2016

Panobinostat enhances cytarabine and daunorubicin sensitivities in AML cells through suppressing the expression of BRCA1, CHK1, and Rad51.

PLoS One 2013 11;8(11):e79106. Epub 2013 Nov 11.

Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan, United States of America ; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan, United States of America ; The State Engineering Laboratory of AIDS Vaccine, College of Life Science, Jilin University, Changchun, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079106PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823972PMC
August 2014

Cellular uptake of imatinib into leukemic cells is independent of human organic cation transporter 1 (OCT1).

Clin Cancer Res 2014 Feb 18;20(4):985-94. Epub 2013 Dec 18.

Authors' Affiliations: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, and University of Tübingen; Institute of Pharmacy, Department of Pharmacology, University of Tübingen; Department of Clinical Pharmacology, University Hospital Tübingen, Tübingen; Institute of Experimental and Clinical Pharmacology, Second Medical Department, University Hospital Schleswig-Holstein, Campus Kiel; Institute of Anatomy and Cell Biology, University of Würzburg, Würzburg, Germany; and Department of Pharmaceutical Sciences, St Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932302PMC
February 2014

Alternative formulations of sorafenib for use in children.

Pediatr Blood Cancer 2013 Oct 20;60(10):1642-6. Epub 2013 Jun 20.

Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN 38105-2794, USA.

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http://doi.wiley.com/10.1002/pbc.24619
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http://dx.doi.org/10.1002/pbc.24619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800690PMC
October 2013

Emergence of polyclonal FLT3 tyrosine kinase domain mutations during sequential therapy with sorafenib and sunitinib in FLT3-ITD-positive acute myeloid leukemia.

Clin Cancer Res 2013 Oct 22;19(20):5758-68. Epub 2013 Aug 22.

Authors' Affiliations: Departments of Pharmaceutical Sciences, Structural Biology, Pathology, and Oncology, Hartwell Center for Bioinformatics and Biotechnology, St. Jude Children's Research Hospital; and Department of Pediatrics, University of Tennessee, Memphis, Tennessee.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878304PMC
October 2013

Contribution of ABCC4-mediated gastric transport to the absorption and efficacy of dasatinib.

Clin Cancer Res 2013 Aug 21;19(16):4359-4370. Epub 2013 Jun 21.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752901PMC
August 2013

CT pulmonary angiography during veno-arterial extracorporeal membrane oxygenation in an adult.

J Med Imaging Radiat Oncol 2013 Jun 25;57(3):345-7. Epub 2012 Jul 25.

Department of Radiology, Sir Charles Gairdner Hospital, Nedlands, Australia.

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http://dx.doi.org/10.1111/j.1754-9485.2012.02413.xDOI Listing
June 2013

Contribution of OATP1B1 and OATP1B3 to the disposition of sorafenib and sorafenib-glucuronide.

Clin Cancer Res 2013 Mar 22;19(6):1458-66. Epub 2013 Jan 22.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-3306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602278PMC
March 2013

Ontogeny and sorafenib metabolism.

Clin Cancer Res 2012 Oct 27;18(20):5788-95. Epub 2012 Aug 27.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-12-1967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490489PMC
October 2012

Influence of smoking on the pharmacokinetics and toxicity profiles of taxane therapy.

Clin Cancer Res 2012 Aug 29;18(16):4425-32. Epub 2012 May 29.

Department of Medical Oncology and Trials and Statistics, Erasmus University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-0728DOI Listing
August 2012

Inhibition of OCTN2-mediated transport of carnitine by etoposide.

Mol Cancer Ther 2012 Apr 2;11(4):921-9. Epub 2012 Mar 2.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-11-0980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466062PMC
April 2012

Marginal increase of sunitinib exposure by grapefruit juice.

Cancer Chemother Pharmacol 2011 Mar 29;67(3):695-703. Epub 2010 May 29.

Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00280-010-1367-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043256PMC
March 2011

Quantitation of sorafenib and its active metabolite sorafenib N-oxide in human plasma by liquid chromatography-tandem mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2010 Nov 9;878(29):3033-8. Epub 2010 Sep 9.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15700232100055
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http://dx.doi.org/10.1016/j.jchromb.2010.08.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956857PMC
November 2010

Castration-dependent pharmacokinetics of docetaxel in patients with prostate cancer.

J Clin Oncol 2010 Oct 20;28(30):4562-7. Epub 2010 Sep 20.

St Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1200/JCO.2010.30.7025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974340PMC
October 2010

Interaction of the multikinase inhibitors sorafenib and sunitinib with solute carriers and ATP-binding cassette transporters.

Clin Cancer Res 2009 Oct 22;15(19):6062-9. Epub 2009 Sep 22.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-0048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774722PMC
October 2009

A phase I dose-finding study of 5-azacytidine in combination with sodium phenylbutyrate in patients with refractory solid tumors.

Clin Cancer Res 2009 Oct 29;15(19):6241-9. Epub 2009 Sep 29.

Chemical Therapeutics Program, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University, Baltimore, Maryland 21231, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-0567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845396PMC
October 2009

Quantification of sunitinib in human plasma by high-performance liquid chromatography-tandem mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2008 Oct 12;874(1-2):84-8. Epub 2008 Sep 12.

Pharmaceutical Sciences Department, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1016/j.jchromb.2008.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612784PMC
October 2008

Stability of sunitinib in oral suspension.

Ann Pharmacother 2008 Jul 24;42(7):962-6. Epub 2008 Jun 24.

Department of Oncology, St Jude Children's Research Hospital, Memphis, TN 38112, USA.

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http://dx.doi.org/10.1345/aph.1K654DOI Listing
July 2008

Comparison of antitumor effects of multitargeted tyrosine kinase inhibitors in acute myelogenous leukemia.

Mol Cancer Ther 2008 May;7(5):1110-20

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, 332 North Lauderdale Street, DTRC Room D1034, Mail Stop 314, Memphis, TN 38105, USA.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-07
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http://dx.doi.org/10.1158/1535-7163.MCT-07-2218DOI Listing
May 2008

Interaction of imatinib with human organic ion carriers.

Clin Cancer Res 2008 May;14(10):3141-8

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphia, TN 38105, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-07-4913DOI Listing
May 2008

Population pharmacokinetic-pharmacodynamic model of the vascular-disrupting agent 5,6-dimethylxanthenone-4-acetic acid in cancer patients.

Clin Cancer Res 2008 Apr;14(7):2102-10

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-1475DOI Listing
April 2008

Phase I and pharmacokinetic study of UCN-01 in combination with irinotecan in patients with solid tumors.

Cancer Chemother Pharmacol 2008 Mar 12;61(3):423-33. Epub 2007 Apr 12.

The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Cancer Research Building I, Baltimore, MD, USA.

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http://dx.doi.org/10.1007/s00280-007-0485-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557498PMC
March 2008

Influence of CYP3A4 inhibition on the steady-state pharmacokinetics of imatinib.

Clin Cancer Res 2007 Dec;13(24):7394-400

Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-0346DOI Listing
December 2007

Evaluation of alternate size descriptors for dose calculation of anticancer drugs in the obese.

J Clin Oncol 2007 Oct;25(30):4707-13

Department of Medical Oncology, Erasmus MC-Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1200/JCO.2007.11.2938DOI Listing
October 2007

Pharmacokinetic and safety study of weekly irinotecan and oral capecitabine in patients with advanced solid cancers.

Invest New Drugs 2007 Jun 30;25(3):237-45. Epub 2006 Dec 30.

Department of Oncology, Albert Einstein College of Medicine and Cancer Center, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1007/s10637-006-9028-1DOI Listing
June 2007

Differential metabolism of gefitinib and erlotinib by human cytochrome P450 enzymes.

Clin Cancer Res 2007 Jun;13(12):3731-7

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-0088DOI Listing
June 2007

Contributing factors of temozolomide resistance in MCF-7 tumor xenograft models.

Cancer Biol Ther 2007 Jun 5;6(6):891-7. Epub 2007 Mar 5.

Department of Radiology, Division of MR Research, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094098PMC
http://dx.doi.org/10.4161/cbt.6.6.4096DOI Listing
June 2007

Activated pregnenolone X-receptor is a target for ketoconazole and its analogs.

Clin Cancer Res 2007 Apr;13(8):2488-95

Albert Einstein Cancer Center, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-1592DOI Listing
April 2007

Association of variant ABCG2 and the pharmacokinetics of epidermal growth factor receptor tyrosine kinase inhibitors in cancer patients.

Cancer Biol Ther 2007 Mar 29;6(3):432-8. Epub 2007 Mar 29.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, USA.

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http://dx.doi.org/10.4161/cbt.6.3.3763DOI Listing
March 2007

A rapid and sensitive method for determination of sorafenib in human plasma using a liquid chromatography/tandem mass spectrometry assay.

J Chromatogr B Analyt Technol Biomed Life Sci 2007 Feb 23;846(1-2):1-7. Epub 2006 Jun 23.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S157002320600459
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http://dx.doi.org/10.1016/j.jchromb.2006.06.005DOI Listing
February 2007

A liquid chromatography/tandem mass spectrometry assay to quantitate MS-275 in human plasma.

J Pharm Biomed Anal 2007 Jan 12;43(2):784-7. Epub 2006 Sep 12.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S073170850600567
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http://dx.doi.org/10.1016/j.jpba.2006.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797151PMC
January 2007

Phase I study of continuous weekly dosing of dimethylamino benzoylphenylurea (BPU) in patients with solid tumours.

Eur J Cancer 2007 Jan 3;43(1):78-86. Epub 2006 Nov 3.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Bunting-Blaustein Cancer Research Building, CRB 1M88, 1650 Orleans Street, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1016/j.ejca.2006.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852493PMC
January 2007

CYP3A phenotyping approach to predict systemic exposure to EGFR tyrosine kinase inhibitors.

J Natl Cancer Inst 2006 Dec;98(23):1714-23

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.

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http://dx.doi.org/10.1093/jnci/djj466DOI Listing
December 2006

Pharmacogenetics of ABCG2 and adverse reactions to gefitinib.

J Natl Cancer Inst 2006 Dec;98(23):1739-42

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.

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http://academic.oup.com/jnci/article/98/23/1739/2521913/Phar
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http://dx.doi.org/10.1093/jnci/djj469DOI Listing
December 2006

A Phase I study of the oral antimetabolite, CS-682, administered once daily 5 days per week in patients with refractory solid tumor malignancies.

Invest New Drugs 2006 Nov;24(6):499-508

Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA, USA.

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http://dx.doi.org/10.1007/s10637-006-8219-0DOI Listing
November 2006

Pharmacokinetics and toxicity of weekly docetaxel in older patients.

Clin Cancer Res 2006 Oct;12(20 Pt 1):6100-5

Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York City, New York 10021, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-0200DOI Listing
October 2006

Binding of gefitinib, an inhibitor of epidermal growth factor receptor-tyrosine kinase, to plasma proteins and blood cells: in vitro and in cancer patients.

Invest New Drugs 2006 Jul;24(4):291-7

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21211, USA.

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http://dx.doi.org/10.1007/s10637-006-5269-2DOI Listing
July 2006

Clinical pharmacokinetics of docetaxel : recent developments.

Clin Pharmacokinet 2006 ;45(3):235-52

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland 21231-1000, USA.

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http://link.springer.com/10.2165/00003088-200645030-00002
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http://dx.doi.org/10.2165/00003088-200645030-00002DOI Listing
April 2006

Population pharmacokinetics of troxacitabine, a novel dioxolane nucleoside analogue.

Clin Cancer Res 2006 Apr;12(7 Pt 1):2158-65

Department of Oncology, Johns Hopkins University and Department of Pharmacy, The Johns Hopkins Hospital, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-2249DOI Listing
April 2006

Ductal access for prevention and therapy of mammary tumors.

Cancer Res 2006 Jan;66(2):638-45

Department of Oncology, Johns Hopkins University School of Medicine, 1650 Orleans Street, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-4329DOI Listing
January 2006

Validation and implementation of a liquid chromatography/tandem mass spectrometry assay to quantitate dimethyl benzoylphenylurea (BPU) and its five metabolites in human plasma and urine for clinical pharmacology studies.

J Chromatogr B Analyt Technol Biomed Life Sci 2005 Dec 25;828(1-2):41-54. Epub 2005 Oct 25.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Bunting-Blaustein Cancer Research Building, Room 1M86, 1650 Orleans Street, Baltimore, MD 21231-1000, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S157002320500633
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http://dx.doi.org/10.1016/j.jchromb.2005.09.027DOI Listing
December 2005

Effect of milk thistle (Silybum marianum) on the pharmacokinetics of irinotecan.

Clin Cancer Res 2005 Nov;11(21):7800-6

Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, the Netherlands.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-05-1288DOI Listing
November 2005

Pharmacokinetics of 5-azacitidine administered with phenylbutyrate in patients with refractory solid tumors or hematologic malignancies.

J Clin Oncol 2005 Jun 25;23(17):3906-11. Epub 2005 Apr 25.

Division of Medical Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1200/JCO.2005.07.450DOI Listing
June 2005

Specific method for determination of gefitinib in human plasma, mouse plasma and tissues using high performance liquid chromatography coupled to tandem mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2005 May;819(1):73-80

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Bunting-Blaustein Cancer Research Building, Room 1M86, 1650 Orleans Street, Baltimore, MD 21231-1000, USA.

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http://dx.doi.org/10.1016/j.jchromb.2005.01.027DOI Listing
May 2005

A sensitive method for determination of COL-3, a chemically modified tetracycline, in human plasma using high-performance liquid chromatography and ultraviolet detection.

J Pharm Biomed Anal 2005 Apr 29;37(4):751-6. Epub 2004 Dec 29.

Division of Medical Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Bunting-Blaustein Cancer Research Building, 1650 Orleans Street, Room 1M90, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1016/j.jpba.2004.10.052DOI Listing
April 2005

Validation and implementation of a method for determination of bryostatin 1 in human plasma by using liquid chromatography/tandem mass spectrometry.

Anal Biochem 2005 Feb;337(1):143-8

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1016/j.ab.2004.10.030DOI Listing
February 2005

A phase I and pharmacokinetic study of short infusions of UCN-01 in patients with refractory solid tumors.

Clin Cancer Res 2005 Jan;11(2 Pt 1):664-71

Division of Medical Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 1650 Orleans Street, Baltimore, MD 21231, USA.

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January 2005