Sharon X Xie

Sharon X Xie

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Pimavanserin versus quetiapine for the treatment of psychosis in Parkinson's disease and dementia with Lewy bodies.

Parkinsonism Relat Disord 2019 12 11;69:119-124. Epub 2019 Nov 11.

University of Pennsylvania, 330 South 9th Street, Philadelphia, PA, 19107, USA. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2019.11.009DOI Listing
December 2019

Putative Antidepressant Effect of Chamomile ( L.) Oral Extract in Subjects with Comorbid Generalized Anxiety Disorder and Depression.

J Altern Complement Med 2019 Dec 5. Epub 2019 Dec 5.

Integrative Medicine Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1089/acm.2019.0252DOI Listing
December 2019

Genetic predictors of survival in behavioral variant frontotemporal degeneration.

Neurology 2019 10 19;93(18):e1707-e1714. Epub 2019 Sep 19.

From the Department of Biostatistics, Epidemiology, and Informatics (C.C., S.X.X.), Department of Neurology (C.T.M., D.J.I., M.G., L.M.M.), Penn Frontotemporal Degeneration Center (C.T.M., D.J.I., M.G., L.M.M.), Translational Neuropathology Research Laboratory (E.B.L.), Department of Pathology and Laboratory Medicine (V.M.V.D., E.B.L., J.Q.T., V.M.-Y.L.), and Center for Neurodegenerative Disease Research (V.M.V.D., E.S., E.B.L., J.Q.T., V.M.-Y.L.), Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1212/WNL.0000000000008387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946477PMC
October 2019

Bias induced by ignoring double truncation inherent in autopsy-confirmed survival studies of neurodegenerative diseases.

Stat Med 2019 Aug 6;38(19):3599-3613. Epub 2019 May 6.

Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1002/sim.8185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625863PMC
August 2019

Epilepsy in families: Age at onset is a familial trait, independent of syndrome.

Ann Neurol 2019 Jul 20;86(1):91-98. Epub 2019 May 20.

Epilepsy Research Centre, Department of Medicine, University of Melbourne (Austin Health), Heidelberg, Victoria, Australia.

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http://dx.doi.org/10.1002/ana.25499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565452PMC
July 2019

Empiric Methods to Account for Pre-analytical Variability in Digital Histopathology in Frontotemporal Lobar Degeneration.

Front Neurosci 2019 3;13:682. Epub 2019 Jul 3.

Penn Digital Neuropathology Laboratory, Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

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http://dx.doi.org/10.3389/fnins.2019.00682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616086PMC
July 2019

Cognitive Functional Abilities in Parkinson's Disease: Agreement Between Patients and Informants.

Mov Disord Clin Pract 2019 Jul 17;6(6):440-445. Epub 2019 May 17.

Departments of Neurology, Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA.

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http://dx.doi.org/10.1002/mdc3.12781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660222PMC
July 2019

Divergent patterns of TDP-43 and tau pathologies in primary progressive aphasia.

Ann Neurol 2019 05 28;85(5):630-643. Epub 2019 Mar 28.

Penn Frontotemporal Degeneration Center, Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1002/ana.25465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538935PMC
May 2019

Older Adult Normative Data for the Sniffin' Sticks Odor Identification Test.

Arch Clin Neuropsychol 2019 Mar;34(2):254-258

Alzheimer's Disease Center, Department of Neurology, Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1093/arclin/acy021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487533PMC
March 2019

Occupational attainment influences longitudinal decline in behavioral variant frontotemporal degeneration.

Brain Imaging Behav 2019 Feb;13(1):293-301

Frontotemporal Degeneration Center, Department of Neurology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, 3 West Gates, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s11682-018-9852-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521965PMC
February 2019

Non-Alzheimer's contributions to dementia and cognitive resilience in The 90+ Study.

Acta Neuropathol 2018 09 18;136(3):377-388. Epub 2018 Jun 18.

Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, Institute on Aging, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/s00401-018-1872-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534149PMC
September 2018

Evaluation of Linguistic Markers of Word-Finding Difficulty and Cognition in Parkinson's Disease.

J Speech Lang Hear Res 2018 07;61(7):1691-1699

Department of Neurology and the Penn Frontotemporal Degenerative Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1044/2018_JSLHR-L-17-0304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195062PMC
July 2018

Statins and Cognition in Parkinson's Disease.

J Parkinsons Dis 2017 ;7(4):661-667

Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.3233/JPD-171113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675567PMC
June 2018

Cox regression model with doubly truncated data.

Biometrics 2018 06 26;74(2):725-733. Epub 2017 Oct 26.

Department of Biostatistics and Epidemiology, University of Pennsylvania, 607 Blockley Hall, 423 Guardian Drive, Philadelphia, Philadelphia 19104, U.S.A.

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http://dx.doi.org/10.1111/biom.12809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920791PMC
June 2018

Differential α-synuclein expression contributes to selective vulnerability of hippocampal neuron subpopulations to fibril-induced toxicity.

Acta Neuropathol 2018 06 3;135(6):855-875. Epub 2018 Mar 3.

Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, Philadelphia, PA, 19104-4283, USA.

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http://dx.doi.org/10.1007/s00401-018-1829-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955788PMC
June 2018

Sequential stages and distribution patterns of aging-related tau astrogliopathy (ARTAG) in the human brain.

Acta Neuropathol Commun 2018 06 11;6(1):50. Epub 2018 Jun 11.

Center for Neurodegenerative Disease Research (CNDR), Institute on Aging and Department of Pathology & Laboratory Medicine, Perelman School of Medicine (PSOM) at the University of Pennsylvania, HUP Maloney 3rd Floor, 36th and Spruce Street, Philadelphia, PA, 19104 - 4283, USA.

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http://dx.doi.org/10.1186/s40478-018-0552-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996526PMC
June 2018

Neocortical origin and progression of gray matter atrophy in nonamnestic Alzheimer's disease.

Neurobiol Aging 2018 03 21;63:75-87. Epub 2017 Nov 21.

Penn Frontotemporal Degeneration Center, University of Pennsylvania, Philadelphia, PA, USA; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.11.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801003PMC
March 2018

CSF tau and β-amyloid predict cerebral synucleinopathy in autopsied Lewy body disorders.

Neurology 2018 03 21;90(12):e1038-e1046. Epub 2018 Feb 21.

From Penn Frontotemporal Degeneration Center (D.J.I., N.N., C.T.M., M.G.), Alzheimer's Disease Core Center (D.A.W., J.Q.T.), Department of Neurology (D.J.I., D.C., R.S.A., C.T.M., D.A.W., D.W., A.C.-P., M.S., A.S., H.I.H., M.G.), Penn Morris K. Udall Parkinson's Disease Research Center of Excellence (D.J.I., R.S.A., C.T.M., D.W., A.C.-P., J.E.D., M.G., J.Q.T.), Center for Neurodegenerative Disease Research (L.M.S., J.Q.T.), Translational Neuropathology Research Laboratory (E.B.L.), Department of Pathology and Laboratory Medicine (E.B.L., L.M.S., J.Q.T.), and Department of Biostatistics and Epidemiology Perelman School of Medicine (S.X.X.), University of Pennsylvania; and Parkinson's Disease Research, Education and Clinical Center (D.W., J.E.D.), Michael J. Crescenz VA Medical Center, Philadelphia, PA.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000005166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874449PMC
March 2018

APOE, thought disorder, and SPARE-AD predict cognitive decline in established Parkinson's disease.

Mov Disord 2018 02 23;33(2):289-297. Epub 2017 Nov 23.

Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1002/mds.27204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809205PMC
February 2018

Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized Placebo-controlled Crossover Study.

Alzheimer Dis Assoc Disord 2017 Apr-Jun;31(2):107-113

*Penn Memory Center Departments of †Biostatistics and Epidemiology ‡Medicine §Radiology ∥Neurology, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1097/WAD.0000000000000202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476214PMC
December 2017

Vitamin D in the Parkinson Associated Risk Syndrome (PARS) study.

Mov Disord 2017 Nov 14;32(11):1636-1640. Epub 2017 Sep 14.

Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1002/mds.27127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721350PMC
November 2017

The Kaplan-Meier Method for Estimating and Comparing Proportions in a Randomized Controlled Trial with Dropouts.

Biostat Epidemiol 2018 30;2(1):23-33. Epub 2017 Nov 30.

Biostatistics, Epidemiology, & Informatics, University of Pennsylvania, 607 Blockley Hall, 423 Guardian Drive, Philadelphia, PA, USA, 215-573-3867.

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http://dx.doi.org/10.1080/24709360.2017.1407866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141203PMC
November 2017

Neuron loss and degeneration in the progression of TDP-43 in frontotemporal lobar degeneration.

Acta Neuropathol Commun 2017 09 6;5(1):68. Epub 2017 Sep 6.

Center for Neurodegenerative Disease Research and Institute on Aging, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1186/s40478-017-0471-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586052PMC
September 2017

Ante mortem cerebrospinal fluid tau levels correlate with postmortem tau pathology in frontotemporal lobar degeneration.

Ann Neurol 2017 Aug 19;82(2):247-258. Epub 2017 Aug 19.

Frontotemporal Degeneration Center, Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1002/ana.24996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776747PMC
August 2017

Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG).

J Neuropathol Exp Neurol 2017 Jul;76(7):605-619

Institute of Neurology, Medical University of Vienna, Vienna, Austria; Center for Neurodegenerative Disease Research, Institute on Aging and Department of Pathology and Laboratory Medicine of the Perelman School of Medicine at the University of Pennsylvania; and Department of Biostatistics and Epidemiology; and Department of Neurosurgery, Center for Brain Injury and Repair, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden; Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK; Department of Neuropathology, Institute of Pathology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida; Northwestern University Feinberg School of Medicine, Northwestern ADC Neuropathology Core, Chicago, Illinois; Clinical Neuropathology, King's College Hospital and London Neurodegenerative Brain Bank, London, UK; Institute of Neuropathology, University Hospital Zurich, Zurich, Switzerland; University of California San Francisco, Institute for Neurodegenerative Diseases, San Francisco, California; Neuropathology Department, Hôpital de La Salpetrière, AP-HP, UPMC-Sorbonne-University, Paris, France; Institute of Neuropathology, Bellvitge University Hospital, University of Barcelona, CIBERNED, Hospitalet de Llobregat, Barcelona, Spain; Discipline of Pathology, Sydney Medical School, The University of Sydney, Sydney, Australia; Neurological Tissue Bank of the Biobank-Hospital Clinic-IDIBAPS, Institut d'Investigacions Biomediques Pi i, Barcelona, Spain; Department of Medicine, Imperial College London, London, UK; IRCCS Foundation "Carlo Besta" Neurological Institute, Milan, Italy; Memory and Aging Center, Department of Neurology, University of California, San Francisco, California; Department of Pathology, University of Sao Paulo Medical School, LIM, São Paulo, Brazil; Brain & Mind Centre, Sydney Medical School, The University of Sydney, and UNSW Medicine & NeuRA, Sydney, Australia; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas; Fishberg Department of Neuroscience, Friedman Brain Institute, and Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, New York; Department of Neuropathology, John Radcliffe Hospital, Oxford, UK; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK; Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Mental Health and Psychiatry, University Hospitals and University of Geneva School of Medicine, Geneva, Switzerland; Institute of Clinical Neurosciences, University of Bristol, Learning & Research Level 2, Southmead Hospital, Bristol, UK; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada; Department of Pathology and Molecular Medicine, Thomayer Hospital, Prague, Czech Republic; Department of Pathology, First Medical Faculty, Charles University, Prague, Czech Republic; Department of Anatomical Pathology, Alfred Hospital , Prahran, Victoria, Australia; Division of Pathology, St. Michael's Hospital, Toronto, Ontario, Canada; Department of Pathology and Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky; Physiopathology in Aging Lab/Brazilian Aging Brain Study Group-LIM22, University of Sao Paulo Medical School, Sao Paulo, Brazil; Behavioral and Cognitive Neurology Unit, Department of Neurology, University of São Paulo , São Paulo, Brazil; Netherlands Brainbank, Amsterdam and Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands; Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan; Institute of Neuroanatomy, Centre for Biomedicine and Medical Technology Mannheim, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany; Department of Neurodegenerative Diseases and Gerontopsychiatry at the University of Bonn Medical Center, Bonn, Germany; Department of Pathology, Brain Research Institute, Niigata University, Niigata, Japan; Department of Neurology, Saitama Medical University International Medical Center, Saitama, Japan; Department of Neuroscience, Katholieke Universiteit-Leuven; and Department of Pathology, Universitaire Ziekenhuizen-Leuven, Leuven, Belgium; Laboratory of Neuropathology, Department of Pathology and Neuropathology, Kepler University Hospital, Medical School, Johannes Kepler University, Linz, Austria; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK; and Department of Pathology and Laboratory Medicine, Centre for Cancer Therapeutics, Ottawa Hospital Research Institute, University of Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1093/jnen/nlx041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251511PMC
July 2017

Comparative effectiveness of electro-acupuncture versus gabapentin for sleep disturbances in breast cancer survivors with hot flashes: a randomized trial.

Menopause 2017 05;24(5):517-523

1Department of Psychology 2Division of Oncology, Memorial University, St. John's, Newfoundland, Canada 3Department of Biostatistics and Epidemiology 4Department of Family Medicine and Community Health, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 5Integrative Medicine Service, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1097/GME.0000000000000779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403590PMC
May 2017

Evaluation of Cerebrospinal Fluid Assay Variability in Alzheimer's Disease.

J Alzheimers Dis 2016 ;51(2):463-70

Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.3233/JAD-151045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930357PMC
December 2016

Long-term chamomile (Matricaria chamomilla L.) treatment for generalized anxiety disorder: A randomized clinical trial.

Phytomedicine 2016 Dec 24;23(14):1735-1742. Epub 2016 Oct 24.

Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

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http://dx.doi.org/10.1016/j.phymed.2016.10.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646235PMC
December 2016

Incident impulse control disorder symptoms and dopamine transporter imaging in Parkinson disease.

J Neurol Neurosurg Psychiatry 2016 Aug 3;87(8):864-70. Epub 2015 Nov 3.

Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA Parkinson's Disease Research, Education and Clinical Centers (PADRECC), Philadelphia Veterans Affairs Medical Center, Philadelphia, Pennsylvania, USA Mental Illness Research, Education and Clinical Centers (MIRECC), Philadelphia Veterans Affairs Medical Center, Philadelphia, Pennsylvania, USA.

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http://jnnp.bmj.com/content/early/2015/11/03/jnnp-2015-31182
Web Search
http://jnnp.bmj.com/lookup/doi/10.1136/jnnp-2015-311827
Publisher Site
http://dx.doi.org/10.1136/jnnp-2015-311827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854795PMC
August 2016

Plasma EGF and cognitive decline in Parkinson's disease and Alzheimer's disease.

Ann Clin Transl Neurol 2016 05 29;3(5):346-55. Epub 2016 Mar 29.

Department of Neurology Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania.

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http://dx.doi.org/10.1002/acn3.299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863747PMC
May 2016

Olfactory impairment predicts cognitive decline in early Parkinson's disease.

Parkinsonism Relat Disord 2016 Apr 19;25:45-51. Epub 2016 Feb 19.

Parkinson's Disease Research, Education, and Clinical Center (PADRECC), Philadelphia VA Medical Center, 3900 Woodland Ave, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.parkreldis.2016.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825674PMC
April 2016

The Penn Parkinson's Daily Activities Questionnaire-15: Psychometric properties of a brief assessment of cognitive instrumental activities of daily living in Parkinson's disease.

Parkinsonism Relat Disord 2016 Apr 21;25:21-6. Epub 2016 Feb 21.

Department of Psychiatry, University of Pennsylvania School of Medicine, 3615 Chestnut St., #330, Philadelphia, PA 19104, USA; Department of Neurology, University of Pennsylvania School of Medicine, 330 S. 9th St., Philadelphia, PA 19107, USA; Philadelphia Veterans Affairs Medical Center, 3900 Woodland Avenue, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2016.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818172PMC
April 2016

Development and Validation of the Parkinson's Disease Medication Beliefs Scale (PD-Rx).

J Parkinsons Dis 2016 04;6(2):383-92

University of Pennsylvania Perelman School of Medicine, Department of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.3233/JPD-150765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884139PMC
April 2016

Research consent capacity varies with executive function and memory in Parkinson's disease.

Mov Disord 2016 Mar 10;31(3):414-7. Epub 2016 Feb 10.

Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1002/mds.26469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5213840PMC
March 2016

CHoosing Options for Insomnia in Cancer Effectively (CHOICE): Design of a patient centered comparative effectiveness trial of acupuncture and cognitive behavior therapy for insomnia.

Contemp Clin Trials 2016 Mar 5;47:349-55. Epub 2016 Mar 5.

The Bendheim Center for Integrative Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cct.2016.02.010DOI Listing
March 2016

The Dementia Severity Rating Scale predicts clinical dementia rating sum of boxes scores.

Alzheimer Dis Assoc Disord 2015 Apr-Jun;29(2):158-60

*Department of Behavioral and Social Sciences, University of the Sciences †Departments of Biostatistics and Epidemiology §Neurology ∥Psychiatry, University of Pennsylvania Perelman School of Medicine ‡Biostatistic Consulting Unit, University of Pennsylvania School of Nursing, Philadelphia, PA.

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http://dx.doi.org/10.1097/WAD.0000000000000031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208973PMC
February 2016

Semi-Automated Digital Image Analysis of Pick's Disease and TDP-43 Proteinopathy.

J Histochem Cytochem 2016 01 4;64(1):54-66. Epub 2015 Nov 4.

Center for Neurodegenerative Disease Research,Department of Pathology & Laboratory Medicine(DJI, MDB, FC, SEA, EBL, VMVD, VML, JQT)

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http://dx.doi.org/10.1369/0022155415614303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810792PMC
January 2016

Amyloid-Beta Positron Emission Tomography Imaging of Alzheimer's Pathology in Parkinson's Disease Dementia.

Mov Disord Clin Pract 2016 Jul-Aug;3(4):367-375. Epub 2016 Jan 5.

Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-3339, USA; Avid Radiopharmaceuticals, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1002/mdc3.12290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971540PMC
January 2016

Inflammatory Eicosanoids Increase Amyloid Precursor Protein Expression via Activation of Multiple Neuronal Receptors.

Sci Rep 2015 Dec 17;5:18286. Epub 2015 Dec 17.

Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, USA.

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http://dx.doi.org/10.1038/srep18286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682150PMC
December 2015

Electroacupuncture Versus Gabapentin for Hot Flashes Among Breast Cancer Survivors: A Randomized Placebo-Controlled Trial.

J Clin Oncol 2015 Nov 24;33(31):3615-20. Epub 2015 Aug 24.

Jun J. Mao, Sharon X. Xie, Angela DeMichele, and John T. Farrar, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Marjorie A. Bowman, Wright State University Boonshoft School of Medicine, Dayton, OH; and Deborah Bruner, Emory University Nell Hodgson Woodruff School of Nursing, Atlanta, GA.

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http://dx.doi.org/10.1200/JCO.2015.60.9412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622101PMC
November 2015

Plasma apolipoprotein A1 associates with age at onset and motor severity in early Parkinson's disease patients.

Mov Disord 2015 Oct 24;30(12):1648-56. Epub 2015 Jul 24.

Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1002/mds.26290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609229PMC
October 2015

Longitudinal study of normal cognition in Parkinson disease.

Neurology 2015 Oct 11;85(15):1276-82. Epub 2015 Sep 11.

From the Departments of Neurology (K.P., J.R., H.H., A.C.-P., J.E.D., J.F.M., L.M.C., N.D., R.S.A., D.W.), Pathology and Laboratory Medicine (J.Q.T.), and Psychiatry (D.W.), Perelman School of Medicine at the University of Pennsylvania; the Department of Biostatistics and Epidemiology (S.X.X.), University of Pennsylvania; Philadelphia Veterans Affairs Medical Center (J.E.D., J.F.M., D.W.); and Avid Radiopharmaceuticals (A.S.), Philadelphia, PA.

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http://www.neurology.org/content/85/15/1276.full.pdf
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http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000200
Publisher Site
http://dx.doi.org/10.1212/WNL.0000000000002001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617168PMC
October 2015

Nonparametric discrete survival function estimation with uncertain endpoints using an internal validation subsample.

Biometrics 2015 Sep 27;71(3):772-81. Epub 2015 Apr 27.

Department of Biostatistics and Epidemiology, University of Pennsylvania, 607 Blockley Hall, 423 Guardian Drive, Philadelphia, Pennsylvania 19104, U.S.A.

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September 2015

Semi-automated quantification of C9orf72 expansion size reveals inverse correlation between hexanucleotide repeat number and disease duration in frontotemporal degeneration.

Acta Neuropathol 2015 Sep 29;130(3):363-72. Epub 2015 May 29.

Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, Perelman School of Medicine at the University of Pennsylvania, 3600 Spruce Street, Philadelphia, PA, 19104-4283, USA,

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http://dx.doi.org/10.1007/s00401-015-1445-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545720PMC
September 2015

Assessing treatment effects with surrogate survival outcomes using an internal validation subsample.

Clin Trials 2015 Aug 14;12(4):333-41. Epub 2015 May 14.

Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, USA

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450363PMC
August 2015

Rivastigmine for mild cognitive impairment in Parkinson disease: a placebo-controlled study.

Mov Disord 2015 Jun 25;30(7):912-8. Epub 2015 Apr 25.

Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA.

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http://dx.doi.org/10.1002/mds.26236DOI Listing
June 2015

Occupational attainment influences survival in autopsy-confirmed frontotemporal degeneration.

Neurology 2015 May 22;84(20):2070-5. Epub 2015 Apr 22.

From the Frontotemporal Degeneration Center, Department of Neurology (L.M., C.T.M., K.R., D.J.I., M.G.), and Department of Biostatistics and Epidemiology (J.Z., S.X.X.), Perelman School of Medicine, University of Pennsylvania, Philadelphia; and The Pennsylvania State University (L.M., A.K.), College of Nursing, University Park, PA.

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http://dx.doi.org/10.1212/WNL.0000000000001595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442102PMC
May 2015

Rhodiola rosea versus sertraline for major depressive disorder: A randomized placebo-controlled trial.

Phytomedicine 2015 Mar 23;22(3):394-9. Epub 2015 Feb 23.

Depression Research Unit, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.

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http://dx.doi.org/10.1016/j.phymed.2015.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385215PMC
March 2015

Hypermethylation of repeat expanded C9orf72 is a clinical and molecular disease modifier.

Acta Neuropathol 2015 Jan 12;129(1):39-52. Epub 2014 Nov 12.

Translational Neuropathology Research Laboratory, Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, 605B Stellar Chance Laboratories, 422 Curie Blvd, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s00401-014-1365-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282973PMC
January 2015

Electroacupuncture for fatigue, sleep, and psychological distress in breast cancer patients with aromatase inhibitor-related arthralgia: a randomized trial.

Cancer 2014 Dec 30;120(23):3744-51. Epub 2014 Jul 30.

Abramson Cancer Center, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania; Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Family Medicine and Community Health, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/cncr.28917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239308PMC
December 2014

Long-Term Chamomile Therapy of Generalized Anxiety Disorder: A Study Protocol for a Randomized, Double-Blind, Placebo- Controlled Trial.

J Clin Trials 2014 Nov 9;4(5). Epub 2014 Oct 9.

Depression Research Unit, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.4172/2167-0870.1000188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650245PMC
November 2014

Expectancy in real and sham electroacupuncture: does believing make it so?

J Natl Cancer Inst Monogr 2014 Nov;2014(50):302-7

Division of Hematology/Oncology (JB, AD), Center for Clinical Epidemiology and Biostatistics (SXX, JTF, AD, JJM), Department of Anesthesia and Critical Care (JTF), Department of Family Medicine and Community Health (SQL, JJM), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (JB, AD); Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA (JB, AD, JJM); Center for Clinical Epidemiology and Biostatistics (SXX, JTF, AD, JJM) and Department of Anesthesia and Critical Care (JTF), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Boonshoft School of Medicine, Wright State University, Dayton, OH (MAB); Nell Hodgson School of Nursing, Emory University, Atlanta, GA (DB).

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http://dx.doi.org/10.1093/jncimonographs/lgu029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411535PMC
November 2014

Course of psychiatric symptoms and global cognition in early Parkinson disease.

Neurology 2014 Sep 15;83(12):1096-103. Epub 2014 Aug 15.

From the Department of Neurology (P.d.l.R.), University Hospital Donostia, San Sebastián, Spain; Department of Biostatistics and Epidemiology (S.X.X.) and Departments of Neurology and Psychiatry (D.W.), Perelman School of Medicine at the University of Pennsylvania (K.S.), Philadelphia; and Department of Veterans Affairs (D.W.), Philadelphia VA Medical Center.

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http://dx.doi.org/10.1212/WNL.0000000000000801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166362PMC
September 2014

Naltrexone for impulse control disorders in Parkinson disease: a placebo-controlled study.

Neurology 2014 Aug 18;83(9):826-33. Epub 2014 Jul 18.

From the Departments of Psychiatry (K.P., D.W.), Biostatistics and Epidemiology (S.X.X.), and Neurology (M.S., H.H., J.E.D., J.M.), University of Pennsylvania, Philadelphia; Avid Radiopharmaceuticals (A.S.), Philadelphia; and Parkinson's Disease Research, Education and Clinical Center (J.E.D., D.W.), Philadelphia Veterans Affairs Medical Center, PA.

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August 2014

Differential longitudinal decline on the Mini-Mental State Examination in frontotemporal lobar degeneration and Alzheimer disease.

Alzheimer Dis Assoc Disord 2013 Oct-Dec;27(4):310-5

Departments of *Biostatistics and Epidemiology ‡Neurology, Perelman School of Medicine, University of Pennsylvania †Department of Neurology, Drexel University College of Medicine, Philadelphia, PA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648632PMC
July 2014

Rhodiola rosea therapy for major depressive disorder: a study protocol for a randomized, double-blind, placebo- controlled trial.

J Clin Trials 2014 Jun;4:170

Depression Research Unit, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.4172/2167-0870.1000170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297663PMC
June 2014

CSF Apo-E levels associate with cognitive decline and MRI changes.

Acta Neuropathol 2014 May 3;127(5):621-32. Epub 2014 Jan 3.

Department of Pathology and Laboratory Medicine, Institute on Aging, Center for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine, HUP, Maloney 3rd, 36th and Spruce Streets, Philadelphia, PA, 19104-4283, USA.

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http://dx.doi.org/10.1007/s00401-013-1236-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988233PMC
May 2014

Mouse models of telomere dysfunction phenocopy skeletal changes found in human age-related osteoporosis.

Dis Model Mech 2014 May 13;7(5):583-92. Epub 2014 Mar 13.

Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1242/dmm.014928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007409PMC
May 2014

A randomised trial of electro-acupuncture for arthralgia related to aromatase inhibitor use.

Eur J Cancer 2014 Jan 24;50(2):267-76. Epub 2013 Oct 24.

Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, PA, United States; Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, PA, United States.

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http://dx.doi.org/10.1016/j.ejca.2013.09.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972040PMC
January 2014

Comparative survey of the topographical distribution of signature molecular lesions in major neurodegenerative diseases.

J Comp Neurol 2013 Dec;521(18):4339-55

Penn Memory Center, Departments of Psychiatry and Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, 19104.

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http://dx.doi.org/10.1002/cne.23430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872132PMC
December 2013

Adjustment for measurement error in evaluating diagnostic biomarkers by using an internal reliability sample.

Stat Med 2013 Nov 14;32(27):4709-25. Epub 2013 Jun 14.

Clinical Research Center, Boston Children's Hospital, Boston, MA 02115, U.S.A.; Department of Psychiatry, Harvard Medical School, Boston, MA 02215, U.S.A.

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http://dx.doi.org/10.1002/sim.5878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808490PMC
November 2013

Longitudinal change in CSF Tau and Aβ biomarkers for up to 48 months in ADNI.

Acta Neuropathol 2013 Nov 29;126(5):659-70. Epub 2013 Jun 29.

Department of Pathology and Laboratory Medicine, Institute on Aging, Center for Neurodegenerative Disease Research, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s00401-013-1151-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875373PMC
November 2013

Development and validation of pedigree classification criteria for frontotemporal lobar degeneration.

JAMA Neurol 2013 Nov;70(11):1411-7

Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, Perelman School of Medicine at the University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1001/jamaneurol.2013.3956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906581PMC
November 2013

Arterial spin labeled MRI in prodromal Alzheimer's disease: A multi-site study.

Neuroimage Clin 2013 30;2:630-6. Epub 2013 Apr 30.

Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA ; Center for Functional Neuroimaging, University of Pennsylvania, Philadelphia, PA, USA ; Penn Memory Center, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.nicl.2013.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777751PMC
November 2013

Comparative accuracies of two common screening instruments for classification of Alzheimer's disease, mild cognitive impairment, and healthy aging.

Alzheimers Dement 2013 Sep 21;9(5):529-37. Epub 2012 Dec 21.

Department of Psychiatry, Neuropsychiatry, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.jalz.2012.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036230PMC
September 2013

Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer's Coordinating Centre.

Brain 2013 Sep 10;136(Pt 9):2697-706. Epub 2013 Jul 10.

Department of Pathology and Laboratory Medicine, Institute on Ageing, Centre for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1093/brain/awt188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858112PMC
September 2013

Joint pain severity predicts premature discontinuation of aromatase inhibitors in breast cancer survivors.

BMC Cancer 2013 Sep 3;13:401. Epub 2013 Sep 3.

Department of Family Medicine and Community Health, University of Pennsylvania, 3400 Spruce Street - 2 Gates, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1186/1471-2407-13-401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847371PMC
September 2013

The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer's disease.

Acta Neuropathol Commun 2013 Jul 6;1:31. Epub 2013 Jul 6.

Department of Pathology and Laboratory Medicine, 3630 Hamilton Walk, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1186/2051-5960-1-31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893579PMC
July 2013

Prevalence and risk factors for insomnia among breast cancer patients on aromatase inhibitors.

Support Care Cancer 2013 Jan 15;21(1):43-51. Epub 2012 May 15.

Department of Family Medicine and Community Health, University of Pennsylvania, 3400 Spruce Street, 2 Gates Building, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1007/s00520-012-1490-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600410PMC
January 2013

Patient-physician communication about complementary and alternative medicine in a radiation oncology setting.

Int J Radiat Oncol Biol Phys 2013 Jan 3;85(1):e1-6. Epub 2012 Oct 3.

Perelman School of Medicine at the University of Pennsylvania, Department of Radiation Oncology, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2012.08.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677204PMC
January 2013

Prenatal healthcare providers' Gaucher disease carrier screening practices.

Genet Med 2012 Oct 31;14(10):844-51. Epub 2012 May 31.

Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/gim.2012.63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530379PMC
October 2012

Neuropathologic substrates of Parkinson disease dementia.

Ann Neurol 2012 Oct 4;72(4):587-98. Epub 2012 Oct 4.

Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Morris K. Udall Parkinson's Disease Center of Excellence, Institute on Aging, Philadelphia, PA, USA.

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http://dx.doi.org/10.1002/ana.23659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484250PMC
October 2012

Development and Validation of an Instrument for Measuring Attitudes and Beliefs about Complementary and Alternative Medicine (CAM) Use among Cancer Patients.

Evid Based Complement Alternat Med 2012 30;2012:798098. Epub 2012 May 30.

Department of Family Medicine and Community Health, University of Pennsylvania Health System, Philadelphia, PA 19104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369496PMC
August 2012

CSF biomarkers cutoffs: the importance of coincident neuropathological diseases.

Acta Neuropathol 2012 Jul 22;124(1):23-35. Epub 2012 Apr 22.

Department of Pathology and Laboratory Medicine, Institute on Aging, Center for Neurodegenerative Disease Research, CNDR, University of Pennsylvania School of Medicine, 3rd Floor Maloney Building, 3600 Spruce Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1007/s00401-012-0983-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551449PMC
July 2012

Predictors of emergent feeding tubes and tracheostomies in amyotrophic lateral sclerosis (ALS).

Amyotroph Lateral Scler 2012 May;13(3):318-25

Robert Wood Johnson Foundation Veterans Affairs Clinical Scholars Program, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.3109/17482968.2012.662987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104116PMC
May 2012