Sharon R Pine

Sharon R Pine

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Sharon R Pine

Sharon R Pine

Publications by authors named "Sharon R Pine"

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pathCHEMO, a generalizable computational framework uncovers molecular pathways of chemoresistance in lung adenocarcinoma.

Commun Biol 2019 6;2:334. Epub 2019 Sep 6.

1Department of Health Informatics, Rutgers School of Health Professions, Rutgers Biomedical and Health Sciences, Newark, NJ 07107 USA.

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http://dx.doi.org/10.1038/s42003-019-0572-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731276PMC
September 2019

Relationship between West African ancestry with lung cancer risk and survival in African Americans.

Cancer Causes Control 2019 Aug 29. Epub 2019 Aug 29.

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/s10552-019-01212-zDOI Listing
August 2019

Circulating Inflammation Proteins Associated With Lung Cancer in African Americans.

J Thorac Oncol 2019 Jul 3;14(7):1192-1203. Epub 2019 Apr 3.

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2019.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592767PMC
July 2019

A Novel Acquired Exon 20 EGFR M766Q Mutation in Lung Adenocarcinoma Mediates Osimertinib Resistance but is Sensitive to Neratinib and Poziotinib.

J Thorac Oncol 2019 Jun 27. Epub 2019 Jun 27.

Rutgers Cancer Institute of New Jersey, Rutgers, The State University of New Jersey, New Brunswick, New Jersey; Department of Medicine, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, New Jersey.

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http://dx.doi.org/10.1016/j.jtho.2019.06.015DOI Listing
June 2019

Rethinking Gamma-secretase Inhibitors for Treatment of Non-small-Cell Lung Cancer: Is Notch the Target?

Authors:
Sharon R Pine

Clin Cancer Res 2018 Dec 13;24(24):6136-6141. Epub 2018 Aug 13.

Rutgers Cancer Institute of New Jersey, Rutgers, The State University of New Jersey, New Brunswick, New Jersey.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-1635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295228PMC
December 2018

Editorial: Harnessing the Power of Patient Derived Models of Cancer.

Front Oncol 2018 6;8:349. Epub 2018 Sep 6.

Department of Medicine, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ, United States.

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https://www.frontiersin.org/article/10.3389/fonc.2018.00349/
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http://dx.doi.org/10.3389/fonc.2018.00349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135905PMC
September 2018

Identifying therapeutic vulnerabilities in lung cancer: application of a chemistry-first approach.

Transl Lung Cancer Res 2018 Sep;7(Suppl 3):S265-S269

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.

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http://tlcr.amegroups.com/article/view/23934/18283
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http://dx.doi.org/10.21037/tlcr.2018.09.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193905PMC
September 2018

Utility of Glioblastoma Patient-Derived Orthotopic Xenografts in Drug Discovery and Personalized Therapy.

Front Oncol 2018 12;8:23. Epub 2018 Feb 12.

Graduate Program in Cellular and Molecular Pharmacology, RBHS-Robert Wood Johnson Medical School, Piscataway, NJ, United States.

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http://dx.doi.org/10.3389/fonc.2018.00023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816058PMC
February 2018

Gamma Secretase Inhibition by BMS-906024 Enhances Efficacy of Paclitaxel in Lung Adenocarcinoma.

Mol Cancer Ther 2017 Dec 4;16(12):2759-2769. Epub 2017 Oct 4.

Rutgers Cancer Institute of New Jersey, Rutgers, The State University of New Jersey, New Brunswick, New Jersey.

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http://dx.doi.org/10.1158/1535-7163.MCT-17-0439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716926PMC
December 2017

Patient-Derived Xenograft Models of Non-Small Cell Lung Cancer and Their Potential Utility in Personalized Medicine.

Front Oncol 2017 19;7. Epub 2017 Jan 19.

Rutgers Cancer Institute of New Jersey, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA; Department of Pharmacology, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA; Department of Medicine, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA.

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http://dx.doi.org/10.3389/fonc.2017.00002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243815PMC
January 2017

SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage.

Nucleic Acids Res 2016 Oct 26;44(18):8855-8869. Epub 2016 Aug 26.

Rutgers Cancer Institute of New Jersey, Rutgers, The State University of New Jersey, New Brunswick, NJ 08903, USA Department of Medicine, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ 08903-0019, USA

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http://dx.doi.org/10.1093/nar/gkw748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062998PMC
October 2016

A combined prognostic serum interleukin-8 and interleukin-6 classifier for stage 1 lung cancer in the prostate, lung, colorectal, and ovarian cancer screening trial.

J Thorac Oncol 2014 Oct;9(10):1494-503

*Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD; †Department of Medicine, Rutgers Cancer Institute of New Jersey, Rutgers, The State University of New Jersey, New Brunswick, NJ; ‡Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD; and §Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD.

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http://dx.doi.org/10.1097/JTO.0000000000000278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272608PMC
October 2014

Asymmetric cell division and template DNA co-segregation in cancer stem cells.

Front Oncol 2014 21;4:226. Epub 2014 Aug 21.

Department of Medicine, Robert Wood Johnson Medical School, Rutgers Cancer Institute of New Jersey, Rutgers, The State University of New Jersey , New Brunswick, NJ , USA.

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http://dx.doi.org/10.3389/fonc.2014.00226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139651PMC
September 2014

Activation of the Notch1 Stem Cell Signaling Pathway during Routine Cell Line Subculture.

Front Oncol 2014 6;4:211. Epub 2014 Aug 6.

Rutgers Cancer Institute of New Jersey , New Brunswick, NJ , USA ; Department of Medicine, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey , New Brunswick, NJ , USA.

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http://dx.doi.org/10.3389/fonc.2014.00211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123601PMC
August 2014

Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma.

Oncotarget 2014 Jun;5(11):3636-50

Department of Pharmacology, Rutgers Graduate School of Biomedical Science, Piscataway, New Jersey; Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey; Department of Medicine, Robert Wood Johnson Medical School, New Brunswick, New Jersey.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116509PMC
http://dx.doi.org/10.18632/oncotarget.1970DOI Listing
June 2014

Asymmetric segregation of template DNA strands in basal-like human breast cancer cell lines.

Mol Cancer 2013 Nov 15;12(1):139. Epub 2013 Nov 15.

Rutgers Cancer Institute of New Jersey, Rutgers, The State University of New Jersey, 195 Little Albany Street, New Brunswick, New Jersey, USA.

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http://dx.doi.org/10.1186/1476-4598-12-139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866575PMC
November 2013

The Notch signaling pathway as a mediator of tumor survival.

Carcinogenesis 2013 Jul 12;34(7):1420-30. Epub 2013 Apr 12.

Department of Medicine, The Cancer Institute of New Jersey, UMDNJ/Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA.

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http://dx.doi.org/10.1093/carcin/bgt127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697894PMC
July 2013

Delineation of breast cancer cell hierarchy identifies the subset responsible for dormancy.

Sci Rep 2012 30;2:906. Epub 2012 Nov 30.

Department of Medicine - Division of Hematology/Oncology, New Jersey Medical School, University of Medicine and Dentistry of New Jersey , Newark, NJ, USA.

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http://dx.doi.org/10.1038/srep00906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510468PMC
May 2013

MDM2 SNP285 does not antagonize the effect of SNP309 in lung cancer.

Int J Cancer 2012 Dec 27;131(11):2710-6. Epub 2012 Apr 27.

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-4258, USA.

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http://dx.doi.org/10.1002/ijc.27573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414691PMC
December 2012

Increased levels of circulating interleukin 6, interleukin 8, C-reactive protein, and risk of lung cancer.

J Natl Cancer Inst 2011 Jul 17;103(14):1112-22. Epub 2011 Jun 17.

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892-4258, USA.

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http://dx.doi.org/10.1093/jnci/djr216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139587PMC
July 2011

C-reactive protein and risk of lung cancer.

J Clin Oncol 2010 Jun 26;28(16):2719-26. Epub 2010 Apr 26.

Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd., Rockville, MD 20852, USA.

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http://jco.ascopubs.org/content/28/16/2719.full.pdf
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2009.27.0454
Publisher Site
http://dx.doi.org/10.1200/JCO.2009.27.0454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881850PMC
June 2010

Microenvironmental modulation of asymmetric cell division in human lung cancer cells.

Proc Natl Acad Sci U S A 2010 Feb 13;107(5):2195-200. Epub 2010 Jan 13.

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.0909390107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836660PMC
February 2010

Childhood exposure to secondhand smoke and functional mannose binding lectin polymorphisms are associated with increased lung cancer risk.

Cancer Epidemiol Biomarkers Prev 2009 Dec;18(12):3375-83

Cancer Prevention Fellowship Program, Office of Preventive Oncology, Division of Cancer Prevention, Laboratory of Human Carcinogenesis, CCR, NCI, NIH, Bethesda, MD 20892-4258, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-09-0986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951599PMC
December 2009

p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence.

Nat Cell Biol 2009 Sep 23;11(9):1135-42. Epub 2009 Aug 23.

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-4258, USA.

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http://dx.doi.org/10.1038/ncb1928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2802853PMC
September 2009

Lung cancer stem cells.

Dis Markers 2008 ;24(4-5):257-66

Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850541PMC
http://dx.doi.org/10.1155/2008/396281DOI Listing
August 2008

Manganese superoxide dismutase gene coding region polymorphisms lack clinical incidence in general population.

DNA Cell Biol 2008 Jun;27(6):321-3

Department of Surgery, James Graham Brown Cancer Center, University of Louisville School of Medicine, Louisville, KY, USA.

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http://dx.doi.org/10.1089/dna.2007.0725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576292PMC
June 2008

Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome.

Blood 2007 Sep 18;110(6):2128-31. Epub 2007 Jun 18.

Department of Pediatrics, Division of Hematology/Oncology, Maria Fareri Children's Hospital and Westchester Medical Center, New York Medical College, Valhalla, NY 10595, USA.

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http://dx.doi.org/10.1182/blood-2007-01-069542DOI Listing
September 2007

Lung cancer survival and functional polymorphisms in MBL2, an innate-immunity gene.

J Natl Cancer Inst 2007 Sep 11;99(18):1401-9. Epub 2007 Sep 11.

Laboratory of Human Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-4258, USA.

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http://dx.doi.org/10.1093/jnci/djm128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278934PMC
September 2007

Down syndrome and GATA1-related transient leukemia.

J Pediatr 2007 Mar;150(3):e34

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http://dx.doi.org/10.1016/j.jpeds.2006.10.055DOI Listing
March 2007

MDM2 SNP309 and SNP354 are not associated with lung cancer risk.

Cancer Epidemiol Biomarkers Prev 2006 Aug;15(8):1559-61

Laboratory of Human Carcinogenesis, National Cancer Institute, Room 3068, Building 37, 37 Convent Drive, Bethesda, MD 20892-4258, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-06-0217DOI Listing
August 2006

Tetrasomy 21 transient leukemia with a GATA1 mutation in a phenotypically normal trisomy 21 mosaic infant: case report and review of the literature.

Pediatr Blood Cancer 2005 Jan;44(1):85-91

Department of Pediatrics, New York Medical College, Valhalla, New York 10595, USA.

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http://dx.doi.org/10.1002/pbc.20161DOI Listing
January 2005

TEL-AML1 fusion precedes differentiation to pre-B cells in childhood acute lymphoblastic leukemia.

Leuk Res 2003 Feb;27(2):155-64

Children's Cancer Research Laboratory, Department of Pediatric, Hematology-Oncology, New York Medical College, Basic Science Building, Room 401, Valhalla, NY 10595, USA.

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http://dx.doi.org/10.1016/s0145-2126(02)00183-2DOI Listing
February 2003

Real-time quantitative PCR: standardized detection of minimal residual disease in pediatric acute lymphoblastic leukemia. Polymerase chain reaction.

J Pediatr Hematol Oncol 2003 Feb;25(2):103-8

Department of Pediatric Hematology/Oncology, New York Medical College, Valhalla 10595, USA.

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February 2003