Publications by authors named "Sharon Glynn"

41Publications

The Role of Nitric Oxide in Cancer: Master Regulator or NOt?

Int J Mol Sci 2020 Dec 10;21(24). Epub 2020 Dec 10.

Discipline of Pathology, Lambe Institute for Translational Research, School of Medicine, National University of Ireland Galway (NUIG), H91 YR71 Galway, Ireland.

View Article and Find Full Text PDF
December 2020

The role of extracellular matrix in tumour angiogenesis: the throne has NOx servants.

Biochem Soc Trans 2020 Nov 5. Epub 2020 Nov 5.

CÚRAM, SFI Research Centre for Medical Devices, National University of Ireland, Galway, Ireland.

View Article and Find Full Text PDF
November 2020

Diabetes Mellitus and Gender Have a Negative Impact on the Outcome of Hip Fracture Surgery-A Pilot Study.

J Orthop Res 2020 04 14;38(4):834-842. Epub 2019 Nov 14.

Department of Trauma & Orthopaedics, Galway University Hospital, Newcastle Road, Galway, Ireland.

View Article and Find Full Text PDF
April 2020

Outcome for triple negative breast cancer in a retrospective cohort with an emphasis on response to platinum-based neoadjuvant therapy.

Breast Cancer Res Treat 2019 Feb 28;174(1):1-13. Epub 2018 Nov 28.

Discipline of Pathology, Lambe Institute for Translational Research, NUI Galway, Costello Road, Galway, Ireland.

View Article and Find Full Text PDF
February 2019

Impact of inducible nitric oxide synthase (iNOS) expression on triple negative breast cancer outcome and activation of EGFR and ERK signaling pathways.

Oncotarget 2017 Oct 26;8(46):80568-80588. Epub 2017 Jul 26.

Discipline of Pathology, Lambe Institute for Translational Research, School of Medicine, National University of Ireland Galway, Galway, Republic of Ireland.

View Article and Find Full Text PDF
October 2017

Inflammation and Nitrosative Stress Effects in Ovarian and Prostate Pathology and Carcinogenesis.

Antioxid Redox Signal 2017 06 22;26(18):1078-1090. Epub 2017 Mar 22.

1 Prostate Cancer Institute, School of Medicine, National University of Ireland Galway , Galway, Ireland .

View Article and Find Full Text PDF
June 2017

Mesenchymal stem cells: key players in cancer progression.

Mol Cancer 2017 02 1;16(1):31. Epub 2017 Feb 1.

Discipline of Pathology, Lambe Institute for Translational Research, School of Medicine, Costello Road, Galway, Ireland.

View Article and Find Full Text PDF
February 2017

Sensitivity Profiles of Human Prostate Cancer Cell Lines to an 80 Kinase Inhibitor Panel.

Anticancer Res 2016 Feb;36(2):633-41

Prostate Cancer Institute, National University of Ireland Galway, Galway, Ireland Discipline of Pathology, Lambe Institute for Translational Research, School of Medicine, National University of Ireland Galway, Galway, Ireland Apoptosis Research Centre, National University of Ireland Galway, Galway, Ireland

View Article and Find Full Text PDF
February 2016

Review of Triple Negative Breast Cancer and the Impact of Inducible Nitric Oxide Synthase on Tumor Biology and Patient Outcomes.

Crit Rev Oncog 2016 ;21(5-6):333-351

Discipline of Pathology, Lambe Institute for Translational Research, School of Medicine, National University of Ireland Galway, Galway, Ireland.

View Article and Find Full Text PDF
January 2016

Signaling and stress: The redox landscape in NOS2 biology.

Free Radic Biol Med 2015 Oct 24;87:204-25. Epub 2015 Jun 24.

Department of Chemistry, University of Arizona, 1306 E. University Blvd., Tucson, AZ 85721, USA. Electronic address:

View Article and Find Full Text PDF
October 2015

A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy.

Biochem Biophys Res Commun 2015 Jan 2;456(1):305-11. Epub 2014 Dec 2.

Apoptosis Research Centre, National University of Ireland Galway, Ireland; School of Natural Sciences, National University of Ireland Galway, Ireland. Electronic address:

View Article and Find Full Text PDF
January 2015

Human endogenous retrovirus K and cancer: Innocent bystander or tumorigenic accomplice?

Int J Cancer 2015 Sep 17;137(6):1249-57. Epub 2014 Jun 17.

Prostate Cancer Institute, National University of Ireland Galway, Galway, Ireland.

View Article and Find Full Text PDF
September 2015

Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression.

Proc Natl Acad Sci U S A 2014 Apr 14;111(17):6323-8. Epub 2014 Apr 14.

Radiation Biology Branch, Tumor and Metastasis Biology Section, Pediatric Oncology Branch, and Laboratory of Human Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

View Article and Find Full Text PDF
April 2014

The yin and yang of nitric oxide in cancer progression.

Carcinogenesis 2013 Mar 25;34(3):503-12. Epub 2013 Jan 25.

Prostate Cancer Institute, National University of Ireland Galway, Dublin, Ireland.

View Article and Find Full Text PDF
March 2013

S-nitrosylation of EGFR and Src activates an oncogenic signaling network in human basal-like breast cancer.

Mol Cancer Res 2012 Sep 9;10(9):1203-15. Epub 2012 Aug 9.

Radiation Biology Branch, National Cancer Institute, NIH, Bethesda, Maryland, USA.

View Article and Find Full Text PDF
September 2012

S-Nitrosation Mediates Multiple Pathways That Lead to Tumor Progression in Estrogen Receptor-Negative Breast Cancer.

For Immunopathol Dis Therap 2012 ;3(2):117-124

Radiation Biology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

View Article and Find Full Text PDF
January 2012

Nitric oxide and protein phosphatase 2A provide novel therapeutic opportunities in ER-negative breast cancer.

Trends Pharmacol Sci 2011 Nov 4;32(11):644-51. Epub 2011 Sep 4.

Radiation Biology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

View Article and Find Full Text PDF
November 2011

Candidate pathways linking inducible nitric oxide synthase to a basal-like transcription pattern and tumor progression in human breast cancer.

Cell Cycle 2011 Feb 15;10(4):619-24. Epub 2011 Feb 15.

Laboratory of Human Carcinogenesis, Center for Cancer Research (CCR), National Cancer Institute (NCI); Bethesda, MD USA.

View Article and Find Full Text PDF
February 2011

The specificity of nitroxyl chemistry is unique among nitrogen oxides in biological systems.

Antioxid Redox Signal 2011 May 16;14(9):1659-74. Epub 2011 Mar 16.

Radiation Biology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

View Article and Find Full Text PDF
May 2011

COX-2 activation is associated with Akt phosphorylation and poor survival in ER-negative, HER2-positive breast cancer.

BMC Cancer 2010 Nov 15;10:626. Epub 2010 Nov 15.

Laboratory of Human Carcinogenesis, Center for Cancer Research (CCR), National Cancer Institute (NCI), NIH, Bethesda, Maryland (MD), USA.

View Article and Find Full Text PDF
November 2010

Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients.

J Clin Invest 2010 Nov 18;120(11):3843-54. Epub 2010 Oct 18.

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA.

View Article and Find Full Text PDF
November 2010

Proteomic analysis of isolated membrane fractions from superinvasive cancer cells.

Biochim Biophys Acta 2007 Jan 30;1774(1):93-101. Epub 2006 Sep 30.

National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.

View Article and Find Full Text PDF
January 2007

Low adhesiveness coupled with high superinvasiveness in vitro predicts the in vivo metastatic potential of a mouse mammary adenocarcinoma cell line.

Anticancer Res 2006 Mar-Apr;26(2A):1001-10

National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Republic of Ireland.

View Article and Find Full Text PDF
May 2006