Sharan K Bagal

Sharan K Bagal

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Sharan K Bagal

Sharan K Bagal

Publications by authors named "Sharan K Bagal"

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13Publications

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Evaluation and Characterization of Trk Kinase Inhibitors for the Treatment of Pain: Reliable Binding Affinity Predictions from Theory and Computation.

J Chem Inf Model 2017 04 4;57(4):897-909. Epub 2017 Apr 4.

Centre for Computational Science, Department of Chemistry, University College London , London WC1H 0AJ, United Kingdom.

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http://pubs.acs.org/doi/10.1021/acs.jcim.6b00780
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http://dx.doi.org/10.1021/acs.jcim.6b00780DOI Listing
April 2017

Voltage gated sodium channels as drug discovery targets.

Channels (Austin) 2015 ;9(6):360-6

a Worldwide Medicinal Chemistry; Pfizer ; Great Abington , Cambridge , UK.

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http://dx.doi.org/10.1080/19336950.2015.1079674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850042PMC
September 2016

Recent progress in sodium channel modulators for pain.

Bioorg Med Chem Lett 2014 Aug 21;24(16):3690-9. Epub 2014 Jun 21.

Worldwide Medicinal Chemistry, Pfizer Neusentis, The Portway Building, Granta Park, Great Abington, Cambridge CB21 6GS, UK.

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http://dx.doi.org/10.1016/j.bmcl.2014.06.038DOI Listing
August 2014

Ion channels as therapeutic targets: a drug discovery perspective.

J Med Chem 2013 Feb 29;56(3):593-624. Epub 2012 Nov 29.

Worldwide Medicinal Chemistry, Pfizer Neusentis , The Portway Building, Granta Park, Great Abington, Cambridge, CB21 6GS, UK.

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http://dx.doi.org/10.1021/jm3011433DOI Listing
February 2013

Minimizing Drug Exposure in the CNS while Maintaining Good Oral Absorption.

ACS Med Chem Lett 2012 Dec 15;3(12):948-50. Epub 2012 Nov 15.

Pfizer Neusentis , Portway Building, Granta Park, Great Abington, Cambridge CB21 6GS, United Kingdom.

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http://dx.doi.org/10.1021/ml300378nDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025750PMC
December 2012

An oxidation and ring contraction approach to the synthesis of (+/-)-1-deoxynojirimycin and (+/-)-1-deoxyaltronojirimycin.

Org Lett 2010 Jan;12(1):136-9

Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK.

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http://dx.doi.org/10.1021/ol902533bDOI Listing
January 2010

Recent advances in biomimetic natural product synthesis.

Nat Prod Rep 2008 Apr 23;25(2):254-97. Epub 2008 Jan 23.

Department of Process Research, Merck & Co., Inc., Rahway, NJ 07065, USA.

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http://dx.doi.org/10.1039/b705909bDOI Listing
April 2008