Publications by authors named "Shao-Cong Sun"

135Publications

Targeting ubiquitin signaling for cancer immunotherapy.

Authors:
Xiaofei Zhou Shao-Cong Sun

Signal Transduct Target Ther 2021 Jan 13;6(1):16. Epub 2021 Jan 13.

Department of Immunology, The University of Texas MD Anderson Cancer Center, 7455 Fannin Street, Box 902, Houston, TX, 77030, USA.

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January 2021

NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.

Authors:
Meidi Gu Xiaofei Zhou Jee Hyung Sohn Lele Zhu Zuliang Jie Jin-Young Yang Xiaofeng Zheng Xiaoping Xie Jie Yang Yaoyao Shi Hans D Brightbill Jae Bum Kim Jing Wang Xuhong Cheng Shao-Cong Sun

Nat Immunol 2021 Jan 4. Epub 2021 Jan 4.

Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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January 2021

The E3 ubiquitin ligase Peli1 regulates the metabolic actions of mTORC1 to suppress antitumor T cell responses.

Authors:
Chun-Jung Ko Lingyun Zhang Zuliang Jie Lele Zhu Xiaofei Zhou Xiaoping Xie Tianxiao Gao Jin-Young Yang Xuhong Cheng Shao-Cong Sun

EMBO J 2021 Jan 20;40(2):e104532. Epub 2020 Nov 20.

Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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January 2021

TRAF2 regulates T cell immunity by maintaining a Tpl2-ERK survival signaling axis in effector and memory CD8 T cells.

Authors:
Xiaoping Xie Lele Zhu Zuliang Jie Yanchuan Li Meidi Gu Xiaofei Zhou Hui Wang Jae-Hoon Chang Chun-Jung Ko Xuhong Cheng Shao-Cong Sun

Cell Mol Immunol 2020 Nov 17. Epub 2020 Nov 17.

Department of Immunology, The University of Texas MD Anderson Cancer Center, 7455 Fannin Street, Box 902, Houston, TX, 77030, USA.

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November 2020

Pellino-1 Regulates the Responses of the Airway to Viral Infection.

Authors:
Elizabeth K Marsh Elizabeth C Prestwich Lynne Williams Amber R Hart Clare F Muir Lisa C Parker Marnix R Jonker Irene H Heijink Wim Timens Mark Fife Tracy Hussell Marc B Hershenson J Kelley Bentley Shao-Cong Sun Ben S Barksby Lee A Borthwick James P Stewart Ian Sabroe David H Dockrell Helen M Marriott

Front Cell Infect Microbiol 2020 31;10:456. Epub 2020 Aug 31.

Department of Infection, Immunity and Cardiovascular Disease, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, United Kingdom.

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August 2020

USP15 suppresses tumor immunity via deubiquitylation and inactivation of TET2.

Authors:
Lei-Lei Chen Matthew D Smith Lei Lv Tadashi Nakagawa Zhijun Li Shao-Cong Sun Nicholas G Brown Yue Xiong Yan-Ping Xu

Sci Adv 2020 Sep 18;6(38). Epub 2020 Sep 18.

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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September 2020

Intestinal Epithelial TBK1 Prevents Differentiation of T-helper 17 Cells and Tumorigenesis in Mice.

Authors:
Jin-Young Yang Zuliang Jie Amber Mathews Xiaofei Zhou Yanchuan Li Meidi Gu Xiaoping Xie Chun-Jung Ko Xuhong Cheng Yuan Qi Jeannelyn S Estrella Jing Wang Shao-Cong Sun

Gastroenterology 2020 Nov 31;159(5):1793-1806. Epub 2020 Jul 31.

Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas; MD Anderson Cancer Center UT Health Graduate School of Biomedical Sciences, Houston, Texas. Electronic address:

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November 2020

Author Correction: The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling.

Authors:
Jin Jin Yichuan Xiao Jae-Hoon Chang Jiayi Yu Hongbo Hu Robyn Starr George C Brittain Mikyoung Chang Xuhong Cheng Shao-Cong Sun

Nat Immunol 2020 Sep;21(9):1134

Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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September 2020

Peli1 signaling blockade attenuates congenital zika syndrome.

Authors:
Huanle Luo Guangyu Li Binbin Wang Bing Tian Junling Gao Jing Zou Shuizhen Shi Shuang Zhu Bi-Hung Peng Awadalkareem Adam Ariza Martinez Kimberly Hein Evandro R Winkelmann Yoseph Mahmoud Xiaofei Zhou Chao Shan Shannan Rossi Scott Weaver Alan D T Barrett Shao-Cong Sun Wenbo Zhang Pei-Yong Shi Ping Wu Tian Wang

PLoS Pathog 2020 06 16;16(6):e1008538. Epub 2020 Jun 16.

Department of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX, United States of America.

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June 2020

Verteporfin Inhibits PD-L1 through Autophagy and the STAT1-IRF1-TRIM28 Signaling Axis, Exerting Antitumor Efficacy.

Authors:
Jiyong Liang Lulu Wang Chao Wang Jianfeng Shen Bojin Su Anantha L Marisetty Dexing Fang Cynthia Kassab Kang Jin Jeong Wei Zhao Yiling Lu Abhinav K Jain Zhicheng Zhou Han Liang Shao-Cong Sun Changming Lu Zhi-Xiang Xu Qinghua Yu Shan Shao XiaoHua Chen Meng Gao Francois X Claret Zhiyong Ding Jian Chen Pingsheng Chen Michelle C Barton Guang Peng Gordon B Mills Amy B Heimberger

Cancer Immunol Res 2020 07 7;8(7):952-965. Epub 2020 Apr 7.

Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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July 2020

A20 restricts inflammation via ubiquitin binding.

Authors:
Shao-Cong Sun

Nat Immunol 2020 04;21(4):362-364

Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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April 2020

TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis.

Authors:
Lele Zhu Yanchuan Li Xiaoping Xie Xiaofei Zhou Meidi Gu Zuliang Jie Chun-Jung Ko Tianxiao Gao Blanca E Hernandez Xuhong Cheng Shao-Cong Sun

Nat Cell Biol 2019 12 2;21(12):1604-1614. Epub 2019 Dec 2.

Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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December 2019

The deubiquitinase Otub1 controls the activation of CD8 T cells and NK cells by regulating IL-15-mediated priming.

Authors:
Xiaofei Zhou Jiayi Yu Xuhong Cheng Baoyu Zhao Ganiraju C Manyam Li Zhang Kimberly Schluns Pingwei Li Jing Wang Shao-Cong Sun

Nat Immunol 2019 07 10;20(7):879-889. Epub 2019 Jun 10.

Department of Immunology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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July 2019

Preventing abnormal NF-κB activation and autoimmunity by Otub1-mediated p100 stabilization.

Authors:
Yanchuan Li Jin-Young Yang Xiaoping Xie Zuliang Jie Lingyun Zhang Jianhong Shi Daniel Lin Meidi Gu Xiaofei Zhou Haiyan S Li Stephanie S Watowich Antrix Jain Sung Yun Jung Jun Qin Xuhong Cheng Shao-Cong Sun

Cell Res 2019 06 13;29(6):474-485. Epub 2019 May 13.

Department of Immunology, The University of Texas MD Anderson Cancer Center, 7455 Fannin Street, Box 902, Houston, TX, 77030, USA.

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June 2019

Author Correction: FGL2 promotes tumor progression in the CNS by suppressing CD103 dendritic cell differentiation.

Authors:
Jun Yan Qingnan Zhao Konrad Gabrusiewicz Ling-Yuan Kong Xueqing Xia Jian Wang Martina Ott Jingda Xu R Eric Davis Longfei Huo Ganesh Rao Shao-Cong Sun Stephanie S Watowich Amy B Heimberger Shulin Li

Nat Commun 2019 02 15;10(1):862. Epub 2019 Feb 15.

Department of Pediatrics-Research, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.

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February 2019

FGL2 promotes tumor progression in the CNS by suppressing CD103 dendritic cell differentiation.

Authors:
Jun Yan Qingnan Zhao Konrad Gabrusiewicz Ling-Yuan Kong Xueqing Xia Jian Wang Martina Ott Jingda Xu R Eric Davis Longfei Huo Ganesh Rao Shao-Cong Sun Stephanie S Watowich Amy B Heimberger Shulin Li

Nat Commun 2019 01 25;10(1):448. Epub 2019 Jan 25.

Department of Pediatrics-Research, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.

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January 2019

Cell type-specific function of TRAF2 and TRAF3 in regulating type I IFN induction.

Authors:
Xiaoping Xie Jin Jin Lele Zhu Zuliang Jie Yanchuan Li Baoyu Zhao Xuhong Cheng Pingwei Li Shao-Cong Sun

Cell Biosci 2019 3;9. Epub 2019 Jan 3.

1Department of Immunology, The University of Texas MD Anderson Cancer Center, 7455 Fannin Street, Box 902, Houston, TX 77030 USA.

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January 2019

FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells.

Authors:
Xiangbo Meng Xiwei Liu Xingdong Guo Shutan Jiang Tingting Chen Zhiqiang Hu Haifeng Liu Yibing Bai Manman Xue Ronggui Hu Shao-Cong Sun Xiaolong Liu Penghui Zhou Xiaowu Huang Lai Wei Wei Yang Chenqi Xu

Nature 2018 12 28;564(7734):130-135. Epub 2018 Nov 28.

State Key Laboratory of Molecular Biology, Shanghai Science Research Center, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.

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December 2018

NIK signaling axis regulates dendritic cell function in intestinal immunity and homeostasis.

Authors:
Zuliang Jie Jin-Young Yang Meidi Gu Hui Wang Xiaoping Xie Yanchuan Li Ting Liu Lele Zhu Jianhong Shi Lingyun Zhang Xiaofei Zhou Donghyun Joo Hans D Brightbill Yingzi Cong Daniel Lin Xuhong Cheng Shao-Cong Sun

Nat Immunol 2018 11 24;19(11):1224-1235. Epub 2018 Sep 24.

Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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November 2018

Peli1 facilitates virus replication and promotes neuroinflammation during West Nile virus infection.

Authors:
Huanle Luo Evandro R Winkelmann Shuang Zhu Wenjuan Ru Elizabeth Mays Jesus A Silvas Lauren L Vollmer Junling Gao Bi-Hung Peng Nathen E Bopp Courtney Cromer Chao Shan Guorui Xie Guangyu Li Robert Tesh Vsevolod L Popov Pei-Yong Shi Shao-Cong Sun Ping Wu Robyn S Klein Shao-Jun Tang Wenbo Zhang Patricia V Aguilar Tian Wang

J Clin Invest 2018 11 24;128(11):4980-4991. Epub 2018 Sep 24.

Department of Microbiology and Immunology.

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November 2018