Shannon L Stott

Shannon L Stott

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Shannon L Stott

Shannon L Stott

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Exploring Dynamics and Structure of Biomolecules, Cryoprotectants, and Water Using Molecular Dynamics Simulations: Implications for Biostabilization and Biopreservation.

Annu Rev Biomed Eng 2019 Jun 10;21:1-31. Epub 2018 Dec 10.

Center for Engineering in Medicine and BioMEMS Resource Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA; email: , ,

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http://dx.doi.org/10.1146/annurev-bioeng-060418-052130DOI Listing
June 2019

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.

Authors:
Clotilde Théry Kenneth W Witwer Elena Aikawa Maria Jose Alcaraz Johnathon D Anderson Ramaroson Andriantsitohaina Anna Antoniou Tanina Arab Fabienne Archer Georgia K Atkin-Smith D Craig Ayre Jean-Marie Bach Daniel Bachurski Hossein Baharvand Leonora Balaj Shawn Baldacchino Natalie N Bauer Amy A Baxter Mary Bebawy Carla Beckham Apolonija Bedina Zavec Abderrahim Benmoussa Anna C Berardi Paolo Bergese Ewa Bielska Cherie Blenkiron Sylwia Bobis-Wozowicz Eric Boilard Wilfrid Boireau Antonella Bongiovanni Francesc E Borràs Steffi Bosch Chantal M Boulanger Xandra Breakefield Andrew M Breglio Meadhbh Á Brennan David R Brigstock Alain Brisson Marike Ld Broekman Jacqueline F Bromberg Paulina Bryl-Górecka Shilpa Buch Amy H Buck Dylan Burger Sara Busatto Dominik Buschmann Benedetta Bussolati Edit I Buzás James Bryan Byrd Giovanni Camussi David Rf Carter Sarah Caruso Lawrence W Chamley Yu-Ting Chang Chihchen Chen Shuai Chen Lesley Cheng Andrew R Chin Aled Clayton Stefano P Clerici Alex Cocks Emanuele Cocucci Robert J Coffey Anabela Cordeiro-da-Silva Yvonne Couch Frank Aw Coumans Beth Coyle Rossella Crescitelli Miria Ferreira Criado Crislyn D'Souza-Schorey Saumya Das Amrita Datta Chaudhuri Paola de Candia Eliezer F De Santana Olivier De Wever Hernando A Del Portillo Tanguy Demaret Sarah Deville Andrew Devitt Bert Dhondt Dolores Di Vizio Lothar C Dieterich Vincenza Dolo Ana Paula Dominguez Rubio Massimo Dominici Mauricio R Dourado Tom Ap Driedonks Filipe V Duarte Heather M Duncan Ramon M Eichenberger Karin Ekström Samir El Andaloussi Celine Elie-Caille Uta Erdbrügger Juan M Falcón-Pérez Farah Fatima Jason E Fish Miguel Flores-Bellver András Försönits Annie Frelet-Barrand Fabia Fricke Gregor Fuhrmann Susanne Gabrielsson Ana Gámez-Valero Chris Gardiner Kathrin Gärtner Raphael Gaudin Yong Song Gho Bernd Giebel Caroline Gilbert Mario Gimona Ilaria Giusti Deborah Ci Goberdhan André Görgens Sharon M Gorski David W Greening Julia Christina Gross Alice Gualerzi Gopal N Gupta Dakota Gustafson Aase Handberg Reka A Haraszti Paul Harrison Hargita Hegyesi An Hendrix Andrew F Hill Fred H Hochberg Karl F Hoffmann Beth Holder Harry Holthofer Baharak Hosseinkhani Guoku Hu Yiyao Huang Veronica Huber Stuart Hunt Ahmed Gamal-Eldin Ibrahim Tsuneya Ikezu Jameel M Inal Mustafa Isin Alena Ivanova Hannah K Jackson Soren Jacobsen Steven M Jay Muthuvel Jayachandran Guido Jenster Lanzhou Jiang Suzanne M Johnson Jennifer C Jones Ambrose Jong Tijana Jovanovic-Talisman Stephanie Jung Raghu Kalluri Shin-Ichi Kano Sukhbir Kaur Yumi Kawamura Evan T Keller Delaram Khamari Elena Khomyakova Anastasia Khvorova Peter Kierulf Kwang Pyo Kim Thomas Kislinger Mikael Klingeborn David J Klinke Miroslaw Kornek Maja M Kosanović Árpád Ferenc Kovács Eva-Maria Krämer-Albers Susanne Krasemann Mirja Krause Igor V Kurochkin Gina D Kusuma Sören Kuypers Saara Laitinen Scott M Langevin Lucia R Languino Joanne Lannigan Cecilia Lässer Louise C Laurent Gregory Lavieu Elisa Lázaro-Ibáñez Soazig Le Lay Myung-Shin Lee Yi Xin Fiona Lee Debora S Lemos Metka Lenassi Aleksandra Leszczynska Isaac Ts Li Ke Liao Sten F Libregts Erzsebet Ligeti Rebecca Lim Sai Kiang Lim Aija Linē Karen Linnemannstöns Alicia Llorente Catherine A Lombard Magdalena J Lorenowicz Ákos M Lörincz Jan Lötvall Jason Lovett Michelle C Lowry Xavier Loyer Quan Lu Barbara Lukomska Taral R Lunavat Sybren Ln Maas Harmeet Malhi Antonio Marcilla Jacopo Mariani Javier Mariscal Elena S Martens-Uzunova Lorena Martin-Jaular M Carmen Martinez Vilma Regina Martins Mathilde Mathieu Suresh Mathivanan Marco Maugeri Lynda K McGinnis Mark J McVey David G Meckes Katie L Meehan Inge Mertens Valentina R Minciacchi Andreas Möller Malene Møller Jørgensen Aizea Morales-Kastresana Jess Morhayim François Mullier Maurizio Muraca Luca Musante Veronika Mussack Dillon C Muth Kathryn H Myburgh Tanbir Najrana Muhammad Nawaz Irina Nazarenko Peter Nejsum Christian Neri Tommaso Neri Rienk Nieuwland Leonardo Nimrichter John P Nolan Esther Nm Nolte-'t Hoen Nicole Noren Hooten Lorraine O'Driscoll Tina O'Grady Ana O'Loghlen Takahiro Ochiya Martin Olivier Alberto Ortiz Luis A Ortiz Xabier Osteikoetxea Ole Østergaard Matias Ostrowski Jaesung Park D Michiel Pegtel Hector Peinado Francesca Perut Michael W Pfaffl Donald G Phinney Bartijn Ch Pieters Ryan C Pink David S Pisetsky Elke Pogge von Strandmann Iva Polakovicova Ivan Kh Poon Bonita H Powell Ilaria Prada Lynn Pulliam Peter Quesenberry Annalisa Radeghieri Robert L Raffai Stefania Raimondo Janusz Rak Marcel I Ramirez Graça Raposo Morsi S Rayyan Neta Regev-Rudzki Franz L Ricklefs Paul D Robbins David D Roberts Silvia C Rodrigues Eva Rohde Sophie Rome Kasper Ma Rouschop Aurelia Rughetti Ashley E Russell Paula Saá Susmita Sahoo Edison Salas-Huenuleo Catherine Sánchez Julie A Saugstad Meike J Saul Raymond M Schiffelers Raphael Schneider Tine Hiorth Schøyen Aaron Scott Eriomina Shahaj Shivani Sharma Olga Shatnyeva Faezeh Shekari Ganesh Vilas Shelke Ashok K Shetty Kiyotaka Shiba Pia R-M Siljander Andreia M Silva Agata Skowronek Orman L Snyder Rodrigo Pedro Soares Barbara W Sódar Carolina Soekmadji Javier Sotillo Philip D Stahl Willem Stoorvogel Shannon L Stott Erwin F Strasser Simon Swift Hidetoshi Tahara Muneesh Tewari Kate Timms Swasti Tiwari Rochelle Tixeira Mercedes Tkach Wei Seong Toh Richard Tomasini Ana Claudia Torrecilhas Juan Pablo Tosar Vasilis Toxavidis Lorena Urbanelli Pieter Vader Bas Wm van Balkom Susanne G van der Grein Jan Van Deun Martijn Jc van Herwijnen Kendall Van Keuren-Jensen Guillaume van Niel Martin E van Royen Andre J van Wijnen M Helena Vasconcelos Ivan J Vechetti Tiago D Veit Laura J Vella Émilie Velot Frederik J Verweij Beate Vestad Jose L Viñas Tamás Visnovitz Krisztina V Vukman Jessica Wahlgren Dionysios C Watson Marca Hm Wauben Alissa Weaver Jason P Webber Viktoria Weber Ann M Wehman Daniel J Weiss Joshua A Welsh Sebastian Wendt Asa M Wheelock Zoltán Wiener Leonie Witte Joy Wolfram Angeliki Xagorari Patricia Xander Jing Xu Xiaomei Yan María Yáñez-Mó Hang Yin Yuana Yuana Valentina Zappulli Jana Zarubova Vytautas Žėkas Jian-Ye Zhang Zezhou Zhao Lei Zheng Alexander R Zheutlin Antje M Zickler Pascale Zimmermann Angela M Zivkovic Davide Zocco Ewa K Zuba-Surma

J Extracell Vesicles 2018 23;7(1):1535750. Epub 2018 Nov 23.

Jagiellonian University, Faculty of Biochemistry, Biophysics and Biotechnology, Department of Cell Biology, Kraków, Poland.

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https://www.tandfonline.com/doi/full/10.1080/20013078.2018.1
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http://dx.doi.org/10.1080/20013078.2018.1535750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322352PMC
November 2018

Blood-based biomarkers for the diagnosis and monitoring of gliomas.

Neuro Oncol 2018 08;20(9):1155-1161

Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1093/neuonc/noy074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071656PMC
August 2018

Effect of Ice Nucleation and Cryoprotectants during High Subzero-Preservation in Endothelialized Microchannels.

ACS Biomater Sci Eng 2018 Aug 26;4(8):3006-3015. Epub 2018 Jun 26.

Center for Engineering in Medicine and BioMEMS Resource Center, Surgical Services, Massachusetts General Hospital, Harvard Medical School, 114 16th Street, Charlestown, Massachusetts 02129, United States.

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http://dx.doi.org/10.1021/acsbiomaterials.8b00648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753837PMC
August 2018

Anti-thrombotic strategies for microfluidic blood processing.

Lab Chip 2018 07;18(15):2146-2155

BioMEMS Resource Center, Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1039/c8lc00035bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082414PMC
July 2018

Molecular Dynamics at the Interface between Ice and Poly(vinyl alcohol) and Ice Recrystallization Inhibition.

Langmuir 2018 05 13;34(17):5116-5123. Epub 2017 Dec 13.

Center for Engineering in Medicine and BioMEMS Resource Center , Massachusetts General Hospital, Harvard Medical School , Boston , Massachusetts 02129 , United States.

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http://dx.doi.org/10.1021/acs.langmuir.7b03243DOI Listing
May 2018

Ultra-fast vitrification of patient-derived circulating tumor cell lines.

PLoS One 2018 23;13(2):e0192734. Epub 2018 Feb 23.

BioMEMS Resource Center, Center for Engineering in Medicine & Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0192734PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825040PMC
April 2018

A highly-occupied, single-cell trapping microarray for determination of cell membrane permeability.

Lab Chip 2017 11;17(23):4077-4088

The Center for Engineering in Medicine, BioMEMS Resource Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1039/c7lc00883jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702951PMC
November 2017

Liquid biopsy for brain tumors.

Expert Rev Mol Diagn 2017 10 6;17(10):943-947. Epub 2017 Sep 6.

a Department of Neurosurgery , Massachusetts General Hospital , Boston , MA , USA.

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http://dx.doi.org/10.1080/14737159.2017.1374854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856481PMC
October 2017

Monolithic Chip for High-throughput Blood Cell Depletion to Sort Rare Circulating Tumor Cells.

Sci Rep 2017 09 7;7(1):10936. Epub 2017 Sep 7.

BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, 02114, USA.

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http://dx.doi.org/10.1038/s41598-017-11119-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589885PMC
September 2017

Clusters of Circulating Tumor Cells: a Biophysical and Technological Perspective.

Curr Opin Biomed Eng 2017 Sep 10;3:13-19. Epub 2017 Aug 10.

Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.

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http://dx.doi.org/10.1016/j.cobme.2017.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720146PMC
September 2017

Preservative solution that stabilizes erythrocyte morphology and leukocyte viability under ambient conditions.

Sci Rep 2017 07 18;7(1):5658. Epub 2017 Jul 18.

BioMEMS Resource Center, Center for Engineering in Medicine, & Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1038/s41598-017-05978-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515929PMC
July 2017

Microfluidic Isolation of Circulating Tumor Cell Clusters by Size and Asymmetry.

Sci Rep 2017 05 26;7(1):2433. Epub 2017 May 26.

Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1038/s41598-017-01150-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446400PMC
May 2017

Controlled ice nucleation using freeze-dried Pseudomonas syringae encapsulated in alginate beads.

Cryobiology 2017 04 14;75:1-6. Epub 2017 Mar 14.

Center for Engineering in Medicine and BioMEMS Resource Center, Surgical Services, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, United States; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, United States; Shriners Hospital for Children, Boston, MA 02114, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cryobiol.2017.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501296PMC
April 2017

Bacterial Ice Nucleation in Monodisperse D2O and H2O-in-Oil Emulsions.

Langmuir 2016 09 18;32(36):9229-36. Epub 2016 Aug 18.

Shriners Hospital for Children, Boston, Massachusetts 02114, United States.

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http://dx.doi.org/10.1021/acs.langmuir.6b02212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501280PMC
September 2016

Deformability-based cell selection with downstream immunofluorescence analysis.

Integr Biol (Camb) 2016 05 21;8(5):654-64. Epub 2016 Mar 21.

Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.

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http://dx.doi.org/10.1039/c5ib00284bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868639PMC
May 2016

Clusters of circulating tumor cells traverse capillary-sized vessels.

Proc Natl Acad Sci U S A 2016 May 18;113(18):4947-52. Epub 2016 Apr 18.

Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114; Shriners Hospital for Children, Boston, MA 02114

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http://dx.doi.org/10.1073/pnas.1524448113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983862PMC
May 2016

The Role of Physical Stabilization in Whole Blood Preservation.

Sci Rep 2016 Feb 15;6:21023. Epub 2016 Feb 15.

BioMEMS Resource Center, Center for Engineering in Medicine, &Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1038/srep21023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753451PMC
February 2016

Deformability of Tumor Cells versus Blood Cells.

Sci Rep 2015 Dec 18;5:18542. Epub 2015 Dec 18.

Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA.

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http://dx.doi.org/10.1038/srep18542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683468PMC
December 2015

NF2/Merlin mediates contact-dependent inhibition of EGFR mobility and internalization via cortical actomyosin.

J Cell Biol 2015 Oct 19;211(2):391-405. Epub 2015 Oct 19.

Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129 Department of Pathology, Massachusetts General Hospital, Charlestown, MA 02129 Department of Pathology, Harvard Medical School, Boston, MA 02115

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http://dx.doi.org/10.1083/jcb.201503081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621825PMC
October 2015

A microfluidic device for label-free, physical capture of circulating tumor cell clusters.

Nat Methods 2015 Jul 18;12(7):685-91. Epub 2015 May 18.

1] Center for Engineering in Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA. [2] Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nmeth.3404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490017PMC
July 2015

MAPK7 Regulates EMT Features and Modulates the Generation of CTCs.

Mol Cancer Res 2015 May 12;13(5):934-43. Epub 2015 Feb 12.

Massachusetts General Hospital Cancer Center and Harvard Medical School, Charlestown, Massachusetts. Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts. Howard Hughes Medical Institute, Chevy Chase, Maryland.

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http://dx.doi.org/10.1158/1541-7786.MCR-14-0604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433453PMC
May 2015

Tunable nanostructured coating for the capture and selective release of viable circulating tumor cells.

Adv Mater 2015 Mar 15;27(9):1593-9. Epub 2015 Jan 15.

Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Building 114, 16th Street, Charlestown, MA, 02129, USA; Shriners Hospital for Children, Harvard Medical School, 51 Blossom Street, Boston, MA, 02114, USA; Department of Surgery, Massachusetts General Hospital, Harvard Medical School 55, 55 Fruit Street, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1002/adma.201404677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492283PMC
March 2015

"Universal" vitrification of cells by ultra-fast cooling.

Technology (Singap World Sci) 2015 Mar;3(1):64-71

BioMEMS Resource Center, Mass achusetts General Hospital, Harvard Medical School, and Shriners Hospital for Children, Boston, MA.

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http://dx.doi.org/10.1142/S2339547815500053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404302PMC
March 2015

Isolation and molecular characterization of circulating melanoma cells.

Cell Rep 2014 May 18;7(3):645-53. Epub 2014 Apr 18.

Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA 02129, USA; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Howard Hughes Medical Institute, Bethesda, MD 20815, USA. Electronic address:

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http://www.cell.com/cell-reports/pdf/S2211-1247(14)00217-4.p
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S221112471400217
Publisher Site
http://dx.doi.org/10.1016/j.celrep.2014.03.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079008PMC
May 2014

Biopolymer system for cell recovery from microfluidic cell capture devices.

Anal Chem 2012 Apr 3;84(8):3682-8. Epub 2012 Apr 3.

Harvard-MIT Division of Health Sciences and Technology, Massachussets Institute of Technology, Cambridge, Massachusetts 02139, United States.

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http://dx.doi.org/10.1021/ac300190jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328665PMC
April 2012

Visualization of intracellular ice formation using high-speed video cryomicroscopy.

Cryobiology 2009 Feb 17;58(1):84-95. Epub 2008 Nov 17.

Woodruff School of Mechanical Engineering and Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA 30332, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cryobiol.2008.11.003DOI Listing
February 2009

Parametric analysis of intercellular ice propagation during cryosurgery, simulated using monte carlo techniques.

Technol Cancer Res Treat 2004 Apr;3(2):113-23

Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA 30332-0405, USA.

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http://dx.doi.org/10.1177/153303460400300204DOI Listing
April 2004