Publications by authors named "Shannon L Risacher"

100Publications

Volumetric GWAS of medial temporal lobe structures identifies an ERC1 locus using ADNI high-resolution T2-weighted MRI data.

Neurobiol Aging 2020 Jul 14;95:81-93. Epub 2020 Jul 14.

Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2020.07.005DOI Listing
July 2020

Neurodegenerative changes in early- and late-onset cognitive impairment with and without brain amyloidosis.

Alzheimers Res Ther 2020 08 5;12(1):93. Epub 2020 Aug 5.

Department of Neurology, Indiana University School of Medicine, 355 W 16th Street, Suite 4022, Indianapolis, IN, 46202, USA.

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http://dx.doi.org/10.1186/s13195-020-00647-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409508PMC
August 2020

Identifying diagnosis-specific genotype-phenotype associations via joint multitask sparse canonical correlation analysis and classification.

Bioinformatics 2020 Jul;36(Supplement_1):i371-i379

Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/bioinformatics/btaa434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355274PMC
July 2020

Novel Markers of Angiogenesis in the Setting of Cognitive Impairment and Dementia.

J Alzheimers Dis 2020 ;75(3):959-969

Indiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.3233/JAD-191293DOI Listing
January 2020

Serum triglycerides in Alzheimer disease: Relation to neuroimaging and CSF biomarkers.

Neurology 2020 05 1;94(20):e2088-e2098. Epub 2020 May 1.

From the Department of Radiology and Imaging Sciences (M.M.B., K.N., S.L.R., T.J., A.J.S.), Center for Neuroimaging, Indiana Alzheimer Disease Center (M.M.B., K.N., S.L.R., T.J., A.J.S.), Medical and Molecular Genetics Department (M.M.B., T.J., A.J.S.), and Medical Scientist Training Program (M.M.B.), Indiana University School of Medicine, Indianapolis; Department of Pediatrics (S.B.), University of Arkansas for Medical Sciences, Little Rock; Department of Environmental Medicine and Public Health (D.K.B.), Icahn School of Medicine at Mt Sinai, New York; NIH-West Coast Metabolomics Center (D.K.B., O.F.), University of California, Davis; Rosa & Co LLC (R.B.), San Carlos, CA; Institute of Bioinformatics and Systems Biology (M.A.), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Pathology & Laboratory Medicine (J.Q.T., L.M.S.), University of Pennsylvania, Philadelphia; Department of Radiology (M.W.W.), Center for Imaging of Neurodegenerative Diseases, San Francisco VA Medical Center/University of California San Francisco; and Department of Psychiatry and Behavioral Sciences (M.A., P.M.D., R.K.-D.), Duke Institute of Brain Sciences (R.K.-D.), and Department of Medicine (R.K.-D.), Duke University, Durham, NC.

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http://dx.doi.org/10.1212/WNL.0000000000009436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526673PMC
May 2020

Visual contrast sensitivity is associated with the presence of cerebral amyloid and tau deposition.

Brain Commun 2020 26;2(1):fcaa019. Epub 2020 Feb 26.

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1093/braincomms/fcaa019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151662PMC
February 2020

The genetic architecture of the human cerebral cortex.

Authors:
Katrina L Grasby Neda Jahanshad Jodie N Painter Lucía Colodro-Conde Janita Bralten Derrek P Hibar Penelope A Lind Fabrizio Pizzagalli Christopher R K Ching Mary Agnes B McMahon Natalia Shatokhina Leo C P Zsembik Sophia I Thomopoulos Alyssa H Zhu Lachlan T Strike Ingrid Agartz Saud Alhusaini Marcio A A Almeida Dag Alnæs Inge K Amlien Micael Andersson Tyler Ard Nicola J Armstrong Allison Ashley-Koch Joshua R Atkins Manon Bernard Rachel M Brouwer Elizabeth E L Buimer Robin Bülow Christian Bürger Dara M Cannon Mallar Chakravarty Qiang Chen Joshua W Cheung Baptiste Couvy-Duchesne Anders M Dale Shareefa Dalvie Tânia K de Araujo Greig I de Zubicaray Sonja M C de Zwarte Anouk den Braber Nhat Trung Doan Katharina Dohm Stefan Ehrlich Hannah-Ruth Engelbrecht Susanne Erk Chun Chieh Fan Iryna O Fedko Sonya F Foley Judith M Ford Masaki Fukunaga Melanie E Garrett Tian Ge Sudheer Giddaluru Aaron L Goldman Melissa J Green Nynke A Groenewold Dominik Grotegerd Tiril P Gurholt Boris A Gutman Narelle K Hansell Mathew A Harris Marc B Harrison Courtney C Haswell Michael Hauser Stefan Herms Dirk J Heslenfeld New Fei Ho David Hoehn Per Hoffmann Laurena Holleran Martine Hoogman Jouke-Jan Hottenga Masashi Ikeda Deborah Janowitz Iris E Jansen Tianye Jia Christiane Jockwitz Ryota Kanai Sherif Karama Dalia Kasperaviciute Tobias Kaufmann Sinead Kelly Masataka Kikuchi Marieke Klein Michael Knapp Annchen R Knodt Bernd Krämer Max Lam Thomas M Lancaster Phil H Lee Tristram A Lett Lindsay B Lewis Iscia Lopes-Cendes Michelle Luciano Fabio Macciardi Andre F Marquand Samuel R Mathias Tracy R Melzer Yuri Milaneschi Nazanin Mirza-Schreiber Jose C V Moreira Thomas W Mühleisen Bertram Müller-Myhsok Pablo Najt Soichiro Nakahara Kwangsik Nho Loes M Olde Loohuis Dimitri Papadopoulos Orfanos John F Pearson Toni L Pitcher Benno Pütz Yann Quidé Anjanibhargavi Ragothaman Faisal M Rashid William R Reay Ronny Redlich Céline S Reinbold Jonathan Repple Geneviève Richard Brandalyn C Riedel Shannon L Risacher Cristiane S Rocha Nina Roth Mota Lauren Salminen Arvin Saremi Andrew J Saykin Fenja Schlag Lianne Schmaal Peter R Schofield Rodrigo Secolin Chin Yang Shapland Li Shen Jean Shin Elena Shumskaya Ida E Sønderby Emma Sprooten Katherine E Tansey Alexander Teumer Anbupalam Thalamuthu Diana Tordesillas-Gutiérrez Jessica A Turner Anne Uhlmann Costanza Ludovica Vallerga Dennis van der Meer Marjolein M J van Donkelaar Liza van Eijk Theo G M van Erp Neeltje E M van Haren Daan van Rooij Marie-José van Tol Jan H Veldink Ellen Verhoef Esther Walton Mingyuan Wang Yunpeng Wang Joanna M Wardlaw Wei Wen Lars T Westlye Christopher D Whelan Stephanie H Witt Katharina Wittfeld Christiane Wolf Thomas Wolfers Jing Qin Wu Clarissa L Yasuda Dario Zaremba Zuo Zhang Marcel P Zwiers Eric Artiges Amelia A Assareh Rosa Ayesa-Arriola Aysenil Belger Christine L Brandt Gregory G Brown Sven Cichon Joanne E Curran Gareth E Davies Franziska Degenhardt Michelle F Dennis Bruno Dietsche Srdjan Djurovic Colin P Doherty Ryan Espiritu Daniel Garijo Yolanda Gil Penny A Gowland Robert C Green Alexander N Häusler Walter Heindel Beng-Choon Ho Wolfgang U Hoffmann Florian Holsboer Georg Homuth Norbert Hosten Clifford R Jack MiHyun Jang Andreas Jansen Nathan A Kimbrel Knut Kolskår Sanne Koops Axel Krug Kelvin O Lim Jurjen J Luykx Daniel H Mathalon Karen A Mather Venkata S Mattay Sarah Matthews Jaqueline Mayoral Van Son Sarah C McEwen Ingrid Melle Derek W Morris Bryon A Mueller Matthias Nauck Jan E Nordvik Markus M Nöthen Daniel S O'Leary Nils Opel Marie-Laure Paillère Martinot G Bruce Pike Adrian Preda Erin B Quinlan Paul E Rasser Varun Ratnakar Simone Reppermund Vidar M Steen Paul A Tooney Fábio R Torres Dick J Veltman James T Voyvodic Robert Whelan Tonya White Hidenaga Yamamori Hieab H H Adams Joshua C Bis Stephanie Debette Charles Decarli Myriam Fornage Vilmundur Gudnason Edith Hofer M Arfan Ikram Lenore Launer W T Longstreth Oscar L Lopez Bernard Mazoyer Thomas H Mosley Gennady V Roshchupkin Claudia L Satizabal Reinhold Schmidt Sudha Seshadri Qiong Yang Marina K M Alvim David Ames Tim J Anderson Ole A Andreassen Alejandro Arias-Vasquez Mark E Bastin Bernhard T Baune Jean C Beckham John Blangero Dorret I Boomsma Henry Brodaty Han G Brunner Randy L Buckner Jan K Buitelaar Juan R Bustillo Wiepke Cahn Murray J Cairns Vince Calhoun Vaughan J Carr Xavier Caseras Svenja Caspers Gianpiero L Cavalleri Fernando Cendes Aiden Corvin Benedicto Crespo-Facorro John C Dalrymple-Alford Udo Dannlowski Eco J C de Geus Ian J Deary Norman Delanty Chantal Depondt Sylvane Desrivières Gary Donohoe Thomas Espeseth Guillén Fernández Simon E Fisher Herta Flor Andreas J Forstner Clyde Francks Barbara Franke David C Glahn Randy L Gollub Hans J Grabe Oliver Gruber Asta K Håberg Ahmad R Hariri Catharina A Hartman Ryota Hashimoto Andreas Heinz Frans A Henskens Manon H J Hillegers Pieter J Hoekstra Avram J Holmes L Elliot Hong William D Hopkins Hilleke E Hulshoff Pol Terry L Jernigan Erik G Jönsson René S Kahn Martin A Kennedy Tilo T J Kircher Peter Kochunov John B J Kwok Stephanie Le Hellard Carmel M Loughland Nicholas G Martin Jean-Luc Martinot Colm McDonald Katie L McMahon Andreas Meyer-Lindenberg Patricia T Michie Rajendra A Morey Bryan Mowry Lars Nyberg Jaap Oosterlaan Roel A Ophoff Christos Pantelis Tomas Paus Zdenka Pausova Brenda W J H Penninx Tinca J C Polderman Danielle Posthuma Marcella Rietschel Joshua L Roffman Laura M Rowland Perminder S Sachdev Philipp G Sämann Ulrich Schall Gunter Schumann Rodney J Scott Kang Sim Sanjay M Sisodiya Jordan W Smoller Iris E Sommer Beate St Pourcain Dan J Stein Arthur W Toga Julian N Trollor Nic J A Van der Wee Dennis van 't Ent Henry Völzke Henrik Walter Bernd Weber Daniel R Weinberger Margaret J Wright Juan Zhou Jason L Stein Paul M Thompson Sarah E Medland

Science 2020 03;367(6484)

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http://dx.doi.org/10.1126/science.aay6690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295264PMC
March 2020

Detecting genetic associations with brain imaging phenotypes in Alzheimer's disease via a novel structured SCCA approach.

Med Image Anal 2020 04 23;61:101656. Epub 2020 Jan 23.

Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.media.2020.101656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099577PMC
April 2020

Prioritization of Cognitive Assessments in Alzheimer's Disease via Learning to Rank using Brain Morphometric Data.

IEEE EMBS Int Conf Biomed Health Inform 2019 May 12;2019. Epub 2019 Sep 12.

Biomedical Informatics Ohio State University, Columbus, OH

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http://dx.doi.org/10.1109/BHI.2019.8834618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957086PMC
May 2019

Dysregulated Fc gamma receptor-mediated phagocytosis pathway in Alzheimer's disease: network-based gene expression analysis.

Neurobiol Aging 2020 04 10;88:24-32. Epub 2019 Dec 10.

Department of Radiology and Imaging Sciences, and the Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085455PMC
April 2020

Regional imaging genetic enrichment analysis.

Bioinformatics 2020 04;36(8):2554-2560

Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/bioinformatics/btz948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178438PMC
April 2020

DIAGNOSIS STATUS GUIDED BRAIN IMAGING GENETICS VIA INTEGRATED REGRESSION AND SPARSE CANONICAL CORRELATION ANALYSIS.

Proc IEEE Int Symp Biomed Imaging 2019 Apr 11;2019:356-359. Epub 2019 Jul 11.

University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1109/ISBI.2019.8759489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914314PMC
April 2019

Multi-modal neuroimaging feature selection with consistent metric constraint for diagnosis of Alzheimer's disease.

Med Image Anal 2020 02 2;60:101625. Epub 2019 Dec 2.

Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.media.2019.101625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980345PMC
February 2020

Genome-wide Network-assisted Association and Enrichment Study of Amyloid Imaging Phenotype in Alzheimer's Disease.

Curr Alzheimer Res 2019 ;16(13):1163-1174

Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.

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http://dx.doi.org/10.2174/1567205016666191121142558DOI Listing
October 2020

Neuroimaging in aging and neurologic diseases.

Handb Clin Neurol 2019 ;167:191-227

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, United States. Electronic address:

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http://dx.doi.org/10.1016/B978-0-12-804766-8.00012-1DOI Listing
April 2020

Mining Regional Imaging Genetic Associations via Voxel-wise Enrichment Analysis.

IEEE EMBS Int Conf Biomed Health Inform 2019 May 12;2019. Epub 2019 Sep 12.

Biostatistics, Epidemiology and Informatics University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1109/BHI.2019.8834450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6860973PMC
May 2019

Genetic architecture of subcortical brain structures in 38,851 individuals.

Authors:
Claudia L Satizabal Hieab H H Adams Derrek P Hibar Charles C White Maria J Knol Jason L Stein Markus Scholz Muralidharan Sargurupremraj Neda Jahanshad Gennady V Roshchupkin Albert V Smith Joshua C Bis Xueqiu Jian Michelle Luciano Edith Hofer Alexander Teumer Sven J van der Lee Jingyun Yang Lisa R Yanek Tom V Lee Shuo Li Yanhui Hu Jia Yu Koh John D Eicher Sylvane Desrivières Alejandro Arias-Vasquez Ganesh Chauhan Lavinia Athanasiu Miguel E Rentería Sungeun Kim David Hoehn Nicola J Armstrong Qiang Chen Avram J Holmes Anouk den Braber Iwona Kloszewska Micael Andersson Thomas Espeseth Oliver Grimm Lucija Abramovic Saud Alhusaini Yuri Milaneschi Martina Papmeyer Tomas Axelsson Stefan Ehrlich Roberto Roiz-Santiañez Bernd Kraemer Asta K Håberg Hannah J Jones G Bruce Pike Dan J Stein Allison Stevens Janita Bralten Meike W Vernooij Tamara B Harris Irina Filippi A Veronica Witte Tulio Guadalupe Katharina Wittfeld Thomas H Mosley James T Becker Nhat Trung Doan Saskia P Hagenaars Yasaman Saba Gabriel Cuellar-Partida Najaf Amin Saima Hilal Kwangsik Nho Nazanin Mirza-Schreiber Konstantinos Arfanakis Diane M Becker David Ames Aaron L Goldman Phil H Lee Dorret I Boomsma Simon Lovestone Sudheer Giddaluru Stephanie Le Hellard Manuel Mattheisen Marc M Bohlken Dalia Kasperaviciute Lianne Schmaal Stephen M Lawrie Ingrid Agartz Esther Walton Diana Tordesillas-Gutierrez Gareth E Davies Jean Shin Jonathan C Ipser Louis N Vinke Martine Hoogman Tianye Jia Ralph Burkhardt Marieke Klein Fabrice Crivello Deborah Janowitz Owen Carmichael Unn K Haukvik Benjamin S Aribisala Helena Schmidt Lachlan T Strike Ching-Yu Cheng Shannon L Risacher Benno Pütz Debra A Fleischman Amelia A Assareh Venkata S Mattay Randy L Buckner Patrizia Mecocci Anders M Dale Sven Cichon Marco P Boks Mar Matarin Brenda W J H Penninx Vince D Calhoun M Mallar Chakravarty Andre F Marquand Christine Macare Shahrzad Kharabian Masouleh Jaap Oosterlaan Philippe Amouyel Katrin Hegenscheid Jerome I Rotter Andrew J Schork David C M Liewald Greig I de Zubicaray Tien Yin Wong Li Shen Philipp G Sämann Henry Brodaty Joshua L Roffman Eco J C de Geus Magda Tsolaki Susanne Erk Kristel R van Eijk Gianpiero L Cavalleri Nic J A van der Wee Andrew M McIntosh Randy L Gollub Kazima B Bulayeva Manon Bernard Jennifer S Richards Jayandra J Himali Markus Loeffler Nanda Rommelse Wolfgang Hoffmann Lars T Westlye Maria C Valdés Hernández Narelle K Hansell Theo G M van Erp Christiane Wolf John B J Kwok Bruno Vellas Andreas Heinz Loes M Olde Loohuis Norman Delanty Beng-Choon Ho Christopher R K Ching Elena Shumskaya Baljeet Singh Albert Hofman Dennis van der Meer Georg Homuth Bruce M Psaty Mark E Bastin Grant W Montgomery Tatiana M Foroud Simone Reppermund Jouke-Jan Hottenga Andrew Simmons Andreas Meyer-Lindenberg Wiepke Cahn Christopher D Whelan Marjolein M J van Donkelaar Qiong Yang Norbert Hosten Robert C Green Anbupalam Thalamuthu Sebastian Mohnke Hilleke E Hulshoff Pol Honghuang Lin Clifford R Jack Peter R Schofield Thomas W Mühleisen Pauline Maillard Steven G Potkin Wei Wen Evan Fletcher Arthur W Toga Oliver Gruber Matthew Huentelman George Davey Smith Lenore J Launer Lars Nyberg Erik G Jönsson Benedicto Crespo-Facorro Nastassja Koen Douglas N Greve André G Uitterlinden Daniel R Weinberger Vidar M Steen Iryna O Fedko Nynke A Groenewold Wiro J Niessen Roberto Toro Christophe Tzourio William T Longstreth M Kamran Ikram Jordan W Smoller Marie-Jose van Tol Jessika E Sussmann Tomas Paus Hervé Lemaître Matthias L Schroeter Bernard Mazoyer Ole A Andreassen Florian Holsboer Chantal Depondt Dick J Veltman Jessica A Turner Zdenka Pausova Gunter Schumann Daan van Rooij Srdjan Djurovic Ian J Deary Katie L McMahon Bertram Müller-Myhsok Rachel M Brouwer Hilkka Soininen Massimo Pandolfo Thomas H Wassink Joshua W Cheung Thomas Wolfers Jean-Luc Martinot Marcel P Zwiers Matthias Nauck Ingrid Melle Nicholas G Martin Ryota Kanai Eric Westman René S Kahn Sanjay M Sisodiya Tonya White Arvin Saremi Hans van Bokhoven Han G Brunner Henry Völzke Margaret J Wright Dennis van 't Ent Markus M Nöthen Roel A Ophoff Jan K Buitelaar Guillén Fernández Perminder S Sachdev Marcella Rietschel Neeltje E M van Haren Simon E Fisher Alexa S Beiser Clyde Francks Andrew J Saykin Karen A Mather Nina Romanczuk-Seiferth Catharina A Hartman Anita L DeStefano Dirk J Heslenfeld Michael W Weiner Henrik Walter Pieter J Hoekstra Paul A Nyquist Barbara Franke David A Bennett Hans J Grabe Andrew D Johnson Christopher Chen Cornelia M van Duijn Oscar L Lopez Myriam Fornage Joanna M Wardlaw Reinhold Schmidt Charles DeCarli Philip L De Jager Arno Villringer Stéphanie Debette Vilmundur Gudnason Sarah E Medland Joshua M Shulman Paul M Thompson Sudha Seshadri M Arfan Ikram

Nat Genet 2019 11 21;51(11):1624-1636. Epub 2019 Oct 21.

Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1038/s41588-019-0511-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055269PMC
November 2019

Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways.

Sci Rep 2019 10 10;9(1):14498. Epub 2019 Oct 10.

Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1038/s41598-019-50507-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787090PMC
October 2019

Identifying progressive imaging genetic patterns via multi-task sparse canonical correlation analysis: a longitudinal study of the ADNI cohort.

Bioinformatics 2019 07;35(14):i474-i483

Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1093/bioinformatics/btz320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613037PMC
July 2019

Plasma amyloid beta levels are associated with cerebral amyloid and tau deposition.

Alzheimers Dement (Amst) 2019 Dec 26;11:510-519. Epub 2019 Jul 26.

Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1016/j.dadm.2019.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661419PMC
December 2019

MIND food and speed of processing training in older adults with low education, the MINDSpeed Alzheimer's disease prevention pilot trial.

Contemp Clin Trials 2019 09 18;84:105814. Epub 2019 Jul 18.

Indiana University Center for Aging Research, Indianapolis, IN, United States of America; Regenstrief Institute, Inc., Indianapolis, IN, United States of America; Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, United States of America.

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http://dx.doi.org/10.1016/j.cct.2019.105814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721976PMC
September 2019

Targeted genetic analysis of cerebral blood flow imaging phenotypes implicates the INPP5D gene.

Neurobiol Aging 2019 09 18;81:213-221. Epub 2019 Jun 18.

Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732252PMC
September 2019

Exercise prevents obesity-induced cognitive decline and white matter damage in mice.

Neurobiol Aging 2019 08 3;80:154-172. Epub 2019 May 3.

The Jackson Laboratory, Bar Harbor, ME, USA; Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.03.018DOI Listing
August 2019

Fast Multi-Task SCCA Learning with Feature Selection for Multi-Modal Brain Imaging Genetics.

Proceedings (IEEE Int Conf Bioinformatics Biomed) 2018 Dec 24;2018:356-361. Epub 2019 Jan 24.

Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine.

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http://dx.doi.org/10.1109/BIBM.2018.8621298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413500PMC
December 2018

Resting state network modularity along the prodromal late onset Alzheimer's disease continuum.

Neuroimage Clin 2019 22;22:101687. Epub 2019 Jan 22.

Department of Radiology and Imaging Sciences, Indiana University School of Medicine (IUSM), Indianapolis, IN, USA; Indiana Alzheimer Disease Center, IUSM, Indianapolis, IN, USA; Indiana University Network Science Institute, Bloomington, IN, USA; School of Informatics, Computing and Engineering, Indiana University, Bloomington, IN, USA; Program in Medical Neuroscience, Paul and Carole Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2019.101687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357852PMC
January 2020

Identification of exon skipping events associated with Alzheimer's disease in the human hippocampus.

BMC Med Genomics 2019 01 31;12(Suppl 1):13. Epub 2019 Jan 31.

Center for Neuroimaging, Department of Radiology and Imaging Sciences and Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1186/s12920-018-0453-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357347PMC
January 2019

Neuropathological correlates and genetic architecture of microglial activation in elderly human brain.

Nat Commun 2019 01 24;10(1):409. Epub 2019 Jan 24.

Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, 630 West 168th Street, New York, NY, 10032, USA.

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http://dx.doi.org/10.1038/s41467-018-08279-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345810PMC
January 2019

Detection of tau in Gerstmann-Sträussler-Scheinker disease (PRNP F198S) by [F]Flortaucipir PET.

Acta Neuropathol Commun 2018 10 29;6(1):114. Epub 2018 Oct 29.

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 355 West 16th Street, Suite 4100, Indianapolis, IN, 46202, USA.

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https://actaneurocomms.biomedcentral.com/articles/10.1186/s4
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http://dx.doi.org/10.1186/s40478-018-0608-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205777PMC
October 2018

Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers.

Alzheimers Dement 2019 02 15;15(2):232-244. Epub 2018 Oct 15.

Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA; Duke Institute of Brain Sciences, Duke University, Durham, NC, USA; Department of Medicine, Duke University, Durham, NC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454538PMC
February 2019

Longitudinal Genotype-Phenotype Association Study through Temporal Structure Auto-Learning Predictive Model.

J Comput Biol 2018 07;25(7):809-824

1 Department of Electrical and Computer Engineering, University of Pittsburgh , Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1089/cmb.2018.0008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067099PMC
July 2018

Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging.

Stroke 2018 08;49(8):1812-1819

From the Institute of Molecular Medicine, McGovern Medical School at The University of Texas Health Science Center at Houston (M.F., X.J.).

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http://dx.doi.org/10.1161/STROKEAHA.118.020689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202149PMC
August 2018

Genetic variation affecting exon skipping contributes to brain structural atrophy in Alzheimer's disease.

AMIA Jt Summits Transl Sci Proc 2018 18;2017:124-131. Epub 2018 May 18.

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961815PMC
May 2018

Memory concerns in the early Alzheimer's disease prodrome: Regional association with tau deposition.

Alzheimers Dement (Amst) 2018 24;10:322-331. Epub 2018 Mar 24.

Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1016/j.dadm.2018.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956937PMC
March 2018

Topographic staging of tau positron emission tomography images.

Alzheimers Dement (Amst) 2018 14;10:221-231. Epub 2018 Feb 14.

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1016/j.dadm.2018.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956800PMC
February 2018

Longitudinal Genotype-Phenotype Association Study via Temporal Structure Auto-Learning Predictive Model.

Res Comput Mol Biol 2017 May 12;10229:287-302. Epub 2017 Apr 12.

Computer Science & Engineering, University of Texas at Arlington, TX, 76019, USA.

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http://dx.doi.org/10.1007/978-3-319-56970-3_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912922PMC
May 2017

Volumetric comparison of hippocampal subfields extracted from 4-minute accelerated vs. 8-minute high-resolution T2-weighted 3T MRI scans.

Brain Imaging Behav 2018 Dec;12(6):1583-1595

Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 355 West 16th Street Suite 4100, Indianapolis, IN, 46202, USA.

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http://dx.doi.org/10.1007/s11682-017-9819-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033688PMC
December 2018

Type 2 diabetes mellitus and cerebrospinal fluid Alzheimer's disease biomarker amyloid β1-42 in Alzheimer's Disease Neuroimaging Initiative participants.

Alzheimers Dement (Amst) 2018 23;10:94-98. Epub 2017 Nov 23.

Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1016/j.dadm.2017.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725206PMC
November 2017

Codon bias among synonymous rare variants is associated with Alzheimer's disease imaging biomarker.

Pac Symp Biocomput 2018 ;23:365-376

Biomedical and Translational Informatics Institute, Geisinger Health System, Danville, PA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756629PMC
August 2018

Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty.

Sci Rep 2017 10 25;7(1):14052. Epub 2017 Oct 25.

Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.

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http://dx.doi.org/10.1038/s41598-017-13930-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656688PMC
October 2017

Alzheimer disease brain atrophy subtypes are associated with cognition and rate of decline.

Neurology 2017 Nov 25;89(21):2176-2186. Epub 2017 Oct 25.

From the Department of Radiology and Imaging Sciences (S.L.R., A.J. Saykin, A.J. Schwarz), Indiana Alzheimer Disease Center (S.L.R., A.J. Saykin), and Department of Biostatistics (P.F.C.), Indiana University School of Medicine; Eli Lilly and Company (W.H.A., A.C., S.S., A.J. Schwarz), Indianapolis; and Department of Psychological and Brain Sciences (A.J. Schwarz), Indiana University, Bloomington.

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http://dx.doi.org/10.1212/WNL.0000000000004670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696639PMC
November 2017

A novel SCCA approach via truncated ℓ1-norm and truncated group lasso for brain imaging genetics.

Bioinformatics 2018 Jan;34(2):278-285

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, IN, USA.

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http://dx.doi.org/10.1093/bioinformatics/btx594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860211PMC
January 2018

Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease.

Neurobiol Aging 2017 Dec 18;60:92-103. Epub 2017 Aug 18.

Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA; Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA; Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774672PMC
December 2017

Identifying Associations Between Brain Imaging Phenotypes and Genetic Factors via A Novel Structured SCCA Approach.

Inf Process Med Imaging 2017 Jun 23;10265:543-555. Epub 2017 May 23.

Radiology and Imaging Sciences, Indiana University School of Medicine, IN, USA.

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http://dx.doi.org/10.1007/978-3-319-59050-9_43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576511PMC
June 2017

Predicting Interrelated Alzheimer's Disease Outcomes via New Self-Learned Structured Low-Rank Model.

Inf Process Med Imaging 2017 Jun 23;10265:198-209. Epub 2017 May 23.

Computer Science & Engineering, University of Texas at Arlington, TX, 76019, USA.

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http://dx.doi.org/10.1007/978-3-319-59050-9_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571742PMC
June 2017

Brain explorer for connectomic analysis.

Brain Inform 2017 Dec 23;4(4):253-269. Epub 2017 Aug 23.

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://link.springer.com/10.1007/s40708-017-0071-9
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http://dx.doi.org/10.1007/s40708-017-0071-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709282PMC
December 2017

Network approaches to systems biology analysis of complex disease: integrative methods for multi-omics data.

Brief Bioinform 2018 11;19(6):1370-1381

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, USA.

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http://dx.doi.org/10.1093/bib/bbx066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454489PMC
November 2018

Genome-wide association study of language performance in Alzheimer's disease.

Brain Lang 2017 09 31;172:22-29. Epub 2017 May 31.

Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA; Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Medicine, University of Washington, Seattle, WA, USA; Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bandl.2017.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583024PMC
September 2017

Tissue-specific network-based genome wide study of amygdala imaging phenotypes to identify functional interaction modules.

Bioinformatics 2017 Oct;33(20):3250-3257

Department of BioHealth Informatics, Indiana University School of Informatics & Computing, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1093/bioinformatics/btx344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410887PMC
October 2017

Plasma Tau Association with Brain Atrophy in Mild Cognitive Impairment and Alzheimer's Disease.

J Alzheimers Dis 2017 ;58(4):1245-1254

Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.3233/JAD-161114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523909PMC
May 2018

Unraveling the Biologic Basis for Domain-Specific Cognitive Decline.

Am J Geriatr Psychiatry 2017 07 11;25(7):741-743. Epub 2017 Apr 11.

Center for Neuroimaging, Indiana Alzheimer Disease Center, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN. Electronic address:

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http://dx.doi.org/10.1016/j.jagp.2017.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870749PMC
July 2017

Age at injury is associated with the long-term cognitive outcome of traumatic brain injuries.

Alzheimers Dement (Amst) 2017 2;6:196-200. Epub 2017 Mar 2.

Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, IN, USA; Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1016/j.dadm.2017.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352716PMC
March 2017

Mining Outcome-relevant Brain Imaging Genetic Associations via Three-way Sparse Canonical Correlation Analysis in Alzheimer's Disease.

Sci Rep 2017 03 14;7:44272. Epub 2017 Mar 14.

College of Computer Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China.

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http://dx.doi.org/10.1038/srep44272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349597PMC
March 2017

Cognitive complaints in older adults at risk for Alzheimer's disease are associated with altered resting-state networks.

Alzheimers Dement (Amst) 2017 22;6:40-49. Epub 2016 Dec 22.

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA; Indiana University Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA; Indiana University Network Science Institute, Indiana University, Bloomington, IN, USA; Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1016/j.dadm.2016.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266473PMC
December 2016

Novel genetic loci associated with hippocampal volume.

Authors:
Derrek P Hibar Hieab H H Adams Neda Jahanshad Ganesh Chauhan Jason L Stein Edith Hofer Miguel E Renteria Joshua C Bis Alejandro Arias-Vasquez M Kamran Ikram Sylvane Desrivières Meike W Vernooij Lucija Abramovic Saud Alhusaini Najaf Amin Micael Andersson Konstantinos Arfanakis Benjamin S Aribisala Nicola J Armstrong Lavinia Athanasiu Tomas Axelsson Ashley H Beecham Alexa Beiser Manon Bernard Susan H Blanton Marc M Bohlken Marco P Boks Janita Bralten Adam M Brickman Owen Carmichael M Mallar Chakravarty Qiang Chen Christopher R K Ching Vincent Chouraki Gabriel Cuellar-Partida Fabrice Crivello Anouk Den Braber Nhat Trung Doan Stefan Ehrlich Sudheer Giddaluru Aaron L Goldman Rebecca F Gottesman Oliver Grimm Michael E Griswold Tulio Guadalupe Boris A Gutman Johanna Hass Unn K Haukvik David Hoehn Avram J Holmes Martine Hoogman Deborah Janowitz Tianye Jia Kjetil N Jørgensen Nazanin Karbalai Dalia Kasperaviciute Sungeun Kim Marieke Klein Bernd Kraemer Phil H Lee David C M Liewald Lorna M Lopez Michelle Luciano Christine Macare Andre F Marquand Mar Matarin Karen A Mather Manuel Mattheisen David R McKay Yuri Milaneschi Susana Muñoz Maniega Kwangsik Nho Allison C Nugent Paul Nyquist Loes M Olde Loohuis Jaap Oosterlaan Martina Papmeyer Lukas Pirpamer Benno Pütz Adaikalavan Ramasamy Jennifer S Richards Shannon L Risacher Roberto Roiz-Santiañez Nanda Rommelse Stefan Ropele Emma J Rose Natalie A Royle Tatjana Rundek Philipp G Sämann Arvin Saremi Claudia L Satizabal Lianne Schmaal Andrew J Schork Li Shen Jean Shin Elena Shumskaya Albert V Smith Emma Sprooten Lachlan T Strike Alexander Teumer Diana Tordesillas-Gutierrez Roberto Toro Daniah Trabzuni Stella Trompet Dhananjay Vaidya Jeroen Van der Grond Sven J Van der Lee Dennis Van der Meer Marjolein M J Van Donkelaar Kristel R Van Eijk Theo G M Van Erp Daan Van Rooij Esther Walton Lars T Westlye Christopher D Whelan Beverly G Windham Anderson M Winkler Katharina Wittfeld Girma Woldehawariat Christiane Wolf Thomas Wolfers Lisa R Yanek Jingyun Yang Alex Zijdenbos Marcel P Zwiers Ingrid Agartz Laura Almasy David Ames Philippe Amouyel Ole A Andreassen Sampath Arepalli Amelia A Assareh Sandra Barral Mark E Bastin Diane M Becker James T Becker David A Bennett John Blangero Hans van Bokhoven Dorret I Boomsma Henry Brodaty Rachel M Brouwer Han G Brunner Randy L Buckner Jan K Buitelaar Kazima B Bulayeva Wiepke Cahn Vince D Calhoun Dara M Cannon Gianpiero L Cavalleri Ching-Yu Cheng Sven Cichon Mark R Cookson Aiden Corvin Benedicto Crespo-Facorro Joanne E Curran Michael Czisch Anders M Dale Gareth E Davies Anton J M De Craen Eco J C De Geus Philip L De Jager Greig I De Zubicaray Ian J Deary Stéphanie Debette Charles DeCarli Norman Delanty Chantal Depondt Anita DeStefano Allissa Dillman Srdjan Djurovic Gary Donohoe Wayne C Drevets Ravi Duggirala Thomas D Dyer Christian Enzinger Susanne Erk Thomas Espeseth Iryna O Fedko Guillén Fernández Luigi Ferrucci Simon E Fisher Debra A Fleischman Ian Ford Myriam Fornage Tatiana M Foroud Peter T Fox Clyde Francks Masaki Fukunaga J Raphael Gibbs David C Glahn Randy L Gollub Harald H H Göring Robert C Green Oliver Gruber Vilmundur Gudnason Sebastian Guelfi Asta K Håberg Narelle K Hansell John Hardy Catharina A Hartman Ryota Hashimoto Katrin Hegenscheid Andreas Heinz Stephanie Le Hellard Dena G Hernandez Dirk J Heslenfeld Beng-Choon Ho Pieter J Hoekstra Wolfgang Hoffmann Albert Hofman Florian Holsboer Georg Homuth Norbert Hosten Jouke-Jan Hottenga Matthew Huentelman Hilleke E Hulshoff Pol Masashi Ikeda Clifford R Jack Mark Jenkinson Robert Johnson Erik G Jönsson J Wouter Jukema René S Kahn Ryota Kanai Iwona Kloszewska David S Knopman Peter Kochunov John B Kwok Stephen M Lawrie Hervé Lemaître Xinmin Liu Dan L Longo Oscar L Lopez Simon Lovestone Oliver Martinez Jean-Luc Martinot Venkata S Mattay Colm McDonald Andrew M McIntosh Francis J McMahon Katie L McMahon Patrizia Mecocci Ingrid Melle Andreas Meyer-Lindenberg Sebastian Mohnke Grant W Montgomery Derek W Morris Thomas H Mosley Thomas W Mühleisen Bertram Müller-Myhsok Michael A Nalls Matthias Nauck Thomas E Nichols Wiro J Niessen Markus M Nöthen Lars Nyberg Kazutaka Ohi Rene L Olvera Roel A Ophoff Massimo Pandolfo Tomas Paus Zdenka Pausova Brenda W J H Penninx G Bruce Pike Steven G Potkin Bruce M Psaty Simone Reppermund Marcella Rietschel Joshua L Roffman Nina Romanczuk-Seiferth Jerome I Rotter Mina Ryten Ralph L Sacco Perminder S Sachdev Andrew J Saykin Reinhold Schmidt Helena Schmidt Peter R Schofield Sigurdur Sigursson Andrew Simmons Andrew Singleton Sanjay M Sisodiya Colin Smith Jordan W Smoller Hilkka Soininen Vidar M Steen David J Stott Jessika E Sussmann Anbupalam Thalamuthu Arthur W Toga Bryan J Traynor Juan Troncoso Magda Tsolaki Christophe Tzourio Andre G Uitterlinden Maria C Valdés Hernández Marcel Van der Brug Aad van der Lugt Nic J A van der Wee Neeltje E M Van Haren Dennis van 't Ent Marie-Jose Van Tol Badri N Vardarajan Bruno Vellas Dick J Veltman Henry Völzke Henrik Walter Joanna M Wardlaw Thomas H Wassink Michael E Weale Daniel R Weinberger Michael W Weiner Wei Wen Eric Westman Tonya White Tien Y Wong Clinton B Wright Ronald H Zielke Alan B Zonderman Nicholas G Martin Cornelia M Van Duijn Margaret J Wright W T Longstreth Gunter Schumann Hans J Grabe Barbara Franke Lenore J Launer Sarah E Medland Sudha Seshadri Paul M Thompson M Arfan Ikram

Nat Commun 2017 01 18;8:13624. Epub 2017 Jan 18.

Department of Epidemiology, Erasmus University Medical Center, 3015 CE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/ncomms13624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253632PMC
January 2017

The effect of the top 20 Alzheimer disease risk genes on gray-matter density and FDG PET brain metabolism.

Alzheimers Dement (Amst) 2016 19;5:53-66. Epub 2016 Dec 19.

Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1016/j.dadm.2016.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198883PMC
December 2016

IDENTIFICATION OF DISCRIMINATIVE IMAGING PROTEOMICS ASSOCIATIONS IN ALZHEIMER'S DISEASE VIA A NOVEL SPARSE CORRELATION MODEL.

Pac Symp Biocomput 2017 ;22:94-104

Department of BioHealth Informatics, Indiana University, Indianapolis, 46202, USA2Center for Computational Biology and Bioinformatics, School of Medicine, Indiana University, Indianapolis, 46202, USA*To whom correspondence should be addressed.,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147740PMC
http://dx.doi.org/10.1142/9789813207813_0010DOI Listing
July 2017

Tau Imaging in Alzheimer's Disease Diagnosis and Clinical Trials.

Neurotherapeutics 2017 01;14(1):62-68

Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1007/s13311-016-0490-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233632PMC
January 2017

Novel genetic loci underlying human intracranial volume identified through genome-wide association.

Authors:
Hieab H H Adams Derrek P Hibar Vincent Chouraki Jason L Stein Paul A Nyquist Miguel E Rentería Stella Trompet Alejandro Arias-Vasquez Sudha Seshadri Sylvane Desrivières Ashley H Beecham Neda Jahanshad Katharina Wittfeld Sven J Van der Lee Lucija Abramovic Saud Alhusaini Najaf Amin Micael Andersson Konstantinos Arfanakis Benjamin S Aribisala Nicola J Armstrong Lavinia Athanasiu Tomas Axelsson Alexa Beiser Manon Bernard Joshua C Bis Laura M E Blanken Susan H Blanton Marc M Bohlken Marco P Boks Janita Bralten Adam M Brickman Owen Carmichael M Mallar Chakravarty Ganesh Chauhan Qiang Chen Christopher R K Ching Gabriel Cuellar-Partida Anouk Den Braber Nhat Trung Doan Stefan Ehrlich Irina Filippi Tian Ge Sudheer Giddaluru Aaron L Goldman Rebecca F Gottesman Corina U Greven Oliver Grimm Michael E Griswold Tulio Guadalupe Johanna Hass Unn K Haukvik Saima Hilal Edith Hofer David Hoehn Avram J Holmes Martine Hoogman Deborah Janowitz Tianye Jia Dalia Kasperaviciute Sungeun Kim Marieke Klein Bernd Kraemer Phil H Lee Jiemin Liao David C M Liewald Lorna M Lopez Michelle Luciano Christine Macare Andre Marquand Mar Matarin Karen A Mather Manuel Mattheisen Bernard Mazoyer David R McKay Rebekah McWhirter Yuri Milaneschi Nazanin Mirza-Schreiber Ryan L Muetzel Susana Muñoz Maniega Kwangsik Nho Allison C Nugent Loes M Olde Loohuis Jaap Oosterlaan Martina Papmeyer Irene Pappa Lukas Pirpamer Sara Pudas Benno Pütz Kumar B Rajan Adaikalavan Ramasamy Jennifer S Richards Shannon L Risacher Roberto Roiz-Santiañez Nanda Rommelse Emma J Rose Natalie A Royle Tatjana Rundek Philipp G Sämann Claudia L Satizabal Lianne Schmaal Andrew J Schork Li Shen Jean Shin Elena Shumskaya Albert V Smith Emma Sprooten Lachlan T Strike Alexander Teumer Russell Thomson Diana Tordesillas-Gutierrez Roberto Toro Daniah Trabzuni Dhananjay Vaidya Jeroen Van der Grond Dennis Van der Meer Marjolein M J Van Donkelaar Kristel R Van Eijk Theo G M Van Erp Daan Van Rooij Esther Walton Lars T Westlye Christopher D Whelan Beverly G Windham Anderson M Winkler Girma Woldehawariat Christiane Wolf Thomas Wolfers Bing Xu Lisa R Yanek Jingyun Yang Alex Zijdenbos Marcel P Zwiers Ingrid Agartz Neelum T Aggarwal Laura Almasy David Ames Philippe Amouyel Ole A Andreassen Sampath Arepalli Amelia A Assareh Sandra Barral Mark E Bastin Diane M Becker James T Becker David A Bennett John Blangero Hans van Bokhoven Dorret I Boomsma Henry Brodaty Rachel M Brouwer Han G Brunner Randy L Buckner Jan K Buitelaar Kazima B Bulayeva Wiepke Cahn Vince D Calhoun Dara M Cannon Gianpiero L Cavalleri Christopher Chen Ching-Yu Cheng Sven Cichon Mark R Cookson Aiden Corvin Benedicto Crespo-Facorro Joanne E Curran Michael Czisch Anders M Dale Gareth E Davies Eco J C De Geus Philip L De Jager Greig I de Zubicaray Norman Delanty Chantal Depondt Anita L DeStefano Allissa Dillman Srdjan Djurovic Gary Donohoe Wayne C Drevets Ravi Duggirala Thomas D Dyer Susanne Erk Thomas Espeseth Denis A Evans Iryna O Fedko Guillén Fernández Luigi Ferrucci Simon E Fisher Debra A Fleischman Ian Ford Tatiana M Foroud Peter T Fox Clyde Francks Masaki Fukunaga J Raphael Gibbs David C Glahn Randy L Gollub Harald H H Göring Hans J Grabe Robert C Green Oliver Gruber Vilmundur Gudnason Sebastian Guelfi Narelle K Hansell John Hardy Catharina A Hartman Ryota Hashimoto Katrin Hegenscheid Andreas Heinz Stephanie Le Hellard Dena G Hernandez Dirk J Heslenfeld Beng-Choon Ho Pieter J Hoekstra Wolfgang Hoffmann Albert Hofman Florian Holsboer Georg Homuth Norbert Hosten Jouke-Jan Hottenga Hilleke E Hulshoff Pol Masashi Ikeda M Kamran Ikram Clifford R Jack Mark Jenkinson Robert Johnson Erik G Jönsson J Wouter Jukema René S Kahn Ryota Kanai Iwona Kloszewska David S Knopman Peter Kochunov John B Kwok Stephen M Lawrie Hervé Lemaître Xinmin Liu Dan L Longo W T Longstreth Oscar L Lopez Simon Lovestone Oliver Martinez Jean-Luc Martinot Venkata S Mattay Colm McDonald Andrew M McIntosh Katie L McMahon Francis J McMahon Patrizia Mecocci Ingrid Melle Andreas Meyer-Lindenberg Sebastian Mohnke Grant W Montgomery Derek W Morris Thomas H Mosley Thomas W Mühleisen Bertram Müller-Myhsok Michael A Nalls Matthias Nauck Thomas E Nichols Wiro J Niessen Markus M Nöthen Lars Nyberg Kazutaka Ohi Rene L Olvera Roel A Ophoff Massimo Pandolfo Tomas Paus Zdenka Pausova Brenda W J H Penninx G Bruce Pike Steven G Potkin Bruce M Psaty Simone Reppermund Marcella Rietschel Joshua L Roffman Nina Romanczuk-Seiferth Jerome I Rotter Mina Ryten Ralph L Sacco Perminder S Sachdev Andrew J Saykin Reinhold Schmidt Peter R Schofield Sigurdur Sigurdsson Andy Simmons Andrew Singleton Sanjay M Sisodiya Colin Smith Jordan W Smoller Hilkka Soininen Velandai Srikanth Vidar M Steen David J Stott Jessika E Sussmann Anbupalam Thalamuthu Henning Tiemeier Arthur W Toga Bryan J Traynor Juan Troncoso Jessica A Turner Christophe Tzourio Andre G Uitterlinden Maria C Valdés Hernández Marcel Van der Brug Aad Van der Lugt Nic J A Van der Wee Cornelia M Van Duijn Neeltje E M Van Haren Dennis Van T Ent Marie-Jose Van Tol Badri N Vardarajan Dick J Veltman Meike W Vernooij Henry Völzke Henrik Walter Joanna M Wardlaw Thomas H Wassink Michael E Weale Daniel R Weinberger Michael W Weiner Wei Wen Eric Westman Tonya White Tien Y Wong Clinton B Wright H Ronald Zielke Alan B Zonderman Ian J Deary Charles DeCarli Helena Schmidt Nicholas G Martin Anton J M De Craen Margaret J Wright Lenore J Launer Gunter Schumann Myriam Fornage Barbara Franke Stéphanie Debette Sarah E Medland M Arfan Ikram Paul M Thompson

Nat Neurosci 2016 12 3;19(12):1569-1582. Epub 2016 Oct 3.

Imaging Genetics Center, USC Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of University of Southern California, Los Angeles, California, USA.

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http://dx.doi.org/10.1038/nn.4398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227112PMC
December 2016

Two-dimensional enrichment analysis for mining high-level imaging genetic associations.

Brain Inform 2017 Mar 13;4(1):27-37. Epub 2016 May 13.

Radiology and Imaging Sciences, Indiana University School of Medicine, 355 West 16th Street Suite 4100, Indianapolis, IN, USA.

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http://dx.doi.org/10.1007/s40708-016-0052-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118198PMC
March 2017

Building a Surface Atlas of Hippocampal Subfields From High Resolution T2-weighted MRI Scans Using Landmark-free Surface Registration.

Conf Proc (Midwest Symp Circuits Syst) 2016 Oct 6;2016. Epub 2017 Mar 6.

Dept. of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN 46202.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995468PMC
http://dx.doi.org/10.1109/MWSCAS.2016.7870109DOI Listing
October 2016

Type 2 diabetes mellitus is associated with brain atrophy and hypometabolism in the ADNI cohort.

Neurology 2016 Aug 6;87(6):595-600. Epub 2016 Jul 6.

From Master of Physician Assistant Studies, School of Health and Rehabilitation Sciences (W.L.), and School of Informatics and Computing (E.H.), Indiana University Purdue University Indianapolis; and Center for Neuroimaging (S.L.R., A.J.S.), Department of Radiology and Imaging Sciences, and Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN.

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http://dx.doi.org/10.1212/WNL.0000000000002950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977372PMC
August 2016

Over-Prescribed Medications/Under-Appreciated Risks.

Mo Med 2016 Jul-Aug;113(4):275

Assistant Professor of Radiology and Imaging Sciences, Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana Alzheimer Disease Center, Indiana University School of Medicine.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139933PMC
September 2018

Erratum to: Traumatic brain injury and age at onset of cognitive impairment in older adults.

J Neurol 2016 Jul;263(7):1286

Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana Alzheimer Disease Center, Indiana University School of Medicine, 355 W. 16th Street, Suite 4100, Indianapolis, IN, 46202, USA.

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http://dx.doi.org/10.1007/s00415-016-8163-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029785PMC
July 2016

Identifying Multimodal Intermediate Phenotypes Between Genetic Risk Factors and Disease Status in Alzheimer's Disease.

Neuroinformatics 2016 10;14(4):439-52

Department of Radiology and Imaging Sciences, School of Medicine, Indiana University, Indianapolis, IN, 46202, USA.

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http://dx.doi.org/10.1007/s12021-016-9307-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010986PMC
October 2016

Integrated Visualization of Human Brain Connectome Data.

Brain Inform Health (2015) 2015 Aug-Sep;9250:295-305. Epub 2015 Aug 21.

Computer and Information Science, Purdue University Indianapolis, IN, USA; Radiology and Imaging Sciences, Indiana University School of Medicine, IN, USA.

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http://dx.doi.org/10.1007/978-3-319-23344-4_29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860269PMC
August 2015

Association Between Anticholinergic Medication Use and Cognition, Brain Metabolism, and Brain Atrophy in Cognitively Normal Older Adults.

JAMA Neurol 2016 06;73(6):721-32

Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indiana University Health Neuroscience Center, Indianapolis2Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis.

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http://archneur.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaneurol.2016.0580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029278PMC
June 2016

[(11)C]PiB PET in Gerstmann-Sträussler-Scheinker disease.

Am J Nucl Med Mol Imaging 2016 28;6(1):84-93. Epub 2016 Jan 28.

Indiana Alzheimer Disease Center, Indiana University School of MedicineIndianapolis, IN, USA; Department of Psychiatry, Indiana University School of MedicineIndianapolis, IN, USA; Department of Pathology and Laboratory Medicine, Indiana University School of MedicineIndianapolis, IN, USA; Department of Medical and Molecular Genetics, Indiana University School of MedicineIndianapolis, IN, USA; Department of Neurology, Indiana University School of MedicineIndianapolis, IN, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749507PMC
April 2016

The Structural and Functional Connectome and Prediction of Risk for Cognitive Impairment in Older Adults.

Curr Behav Neurosci Rep 2015 Dec 29;2(4):234-245. Epub 2015 Oct 29.

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA; Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA; Medical Neuroscience Program, Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA; Indiana University Network Science Institute, Indiana University, Indianapolis, IN, USA.

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http://dx.doi.org/10.1007/s40473-015-0056-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809258PMC
December 2015

Traumatic brain injury and age at onset of cognitive impairment in older adults.

J Neurol 2016 Jul 23;263(7):1280-5. Epub 2016 Mar 23.

Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana Alzheimer Disease Center, Indiana University School of Medicine, 355 W. 16th Street, Suite 4100, Indianapolis, IN, 46202, USA.

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http://dx.doi.org/10.1007/s00415-016-8093-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029270PMC
July 2016

Structured sparse canonical correlation analysis for brain imaging genetics: an improved GraphNet method.

Bioinformatics 2016 05 21;32(10):1544-51. Epub 2016 Jan 21.

Department of Radiology and Imaging Sciences, Indiana University, Indianapolis, IN, USA.

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http://dx.doi.org/10.1093/bioinformatics/btw033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907375PMC
May 2016

DIAGNOSIS-GUIDED METHOD FOR IDENTIFYING MULTI-MODALITY NEUROIMAGING BIOMARKERS ASSOCIATED WITH GENETIC RISK FACTORS IN ALZHEIMER'S DISEASE.

Pac Symp Biocomput 2016 ;21:108-19

College of Computer Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing, 210016, China2Department of Radiology & Imaging Science, School of Medicine, Indiana University, Indianapolis, 46202, USA,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719777PMC
October 2016

Sparse Canonical Correlation Analysis via Truncated -norm with Application to Brain Imaging Genetics.

Proceedings (IEEE Int Conf Bioinformatics Biomed) 2016 19;2016:707-711. Epub 2017 Jan 19.

Indiana University School of Medicine, Indianapolis, USA 46202.

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http://dx.doi.org/10.1109/BIBM.2016.7822605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627624PMC
January 2017

A New Statistical Image Analysis Approach and Its Application to Hippocampal Morphometry.

Med Imaging Augment Real (2016) 2016 14;9805:302-310. Epub 2016 Aug 14.

Radiology and Imaging Sciences, Indiana University School of Medicine, IN, USA.

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http://dx.doi.org/10.1007/978-3-319-43775-0_27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605920PMC
August 2016

Two-dimensional Enrichment Analysis for Mining High-level Imaging Genetic Associations.

Brain Inform Health (2015) 2015 Aug-Sep;9250:115-124. Epub 2015 Aug 21.

Biomedical Informatics, School of Medicine, University of Pennsylvania, PA, USA.

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http://dx.doi.org/10.1007/978-3-319-23344-4_12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640356PMC
August 2015

GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP.

Brain 2015 Oct 11;138(Pt 10):3076-88. Epub 2015 Aug 11.

1 Centre for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN 46202, USA 1 Centre for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN 46202, USA 4 Indiana Alzheimer Disease Centre, Indiana University School of Medicine, Indianapolis, IN 46202, USA 5 Centre for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN 46202, USA

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http://dx.doi.org/10.1093/brain/awv231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671479PMC
October 2015

Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans.

Alzheimers Dement 2015 Jul;11(7):792-814

Department of Radiology, University of California-San Francisco, San Francisco, CA, USA; Department of Medicine, University of California-San Francisco, San Francisco, CA, USA; Department of Psychiatry, University of California-San Francisco, San Francisco, CA, USA; Center for Imaging of Neurodegenerative Diseases, San Francisco VA Medical Center, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.jalz.2015.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510473PMC
July 2015