Shannon Bruse

Shannon Bruse

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Shannon Bruse

Shannon Bruse

Publications by authors named "Shannon Bruse"

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Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.

Nat Commun 2018 06 13;9(1):2252. Epub 2018 Jun 13.

Regeneron Pharmaceuticals, Tarrytown, 10591, NY, USA.

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http://dx.doi.org/10.1038/s41467-018-04611-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997992PMC
June 2018

Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease.

N Engl J Med 2017 07 24;377(3):211-221. Epub 2017 May 24.

From Regeneron Genetics Center (F.E.D., C.O., C.S., O.G., S.M., C.V.V.H., S.B., L.H., A.L., J.P., N.S., A.J.M., J.D.O., J.G.R., A.R.S., I.B.B., T.M.T., G.D.Y., S.J.M., A. Baras) and Regeneron Pharmaceuticals (V.G., H.M.D., A.Z., W.S., N.S., A.J.M., S.H., A. Bouzelmat, R.Z., B.S., R.P., D.G., G.A.H., W.J.S., P.B., G.D.Y., S.J.M., J.G.) Tarrytown, NY; the Department of Medicine, Division of Translational Medicine and Human Genetics (R.L.D.), and Departments of Surgery (S.D.) and Genetics and Medicine (A.S., D.J.R.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, and Geisinger Health System, Danville (J.B.L., M.F.M., M.D.R., H.L.K., D.H.L., D.J.C.) - both in Pennsylvania; the Division of Endocrinology and Metabolism, Department of Internal Medicine (W.H.H.S., I.-T.L.) and Cardiovascular Center (K.-W.L.), Taichung Veterans General Hospital, Institute of Medical Technology, National Chung-Hsing University (W.H.H.S.), School of Medicine, Chung Shan Medical University (I.-T.L.), and the Department of Medicine, China Medical University (K.-W.L.), Taichung, and School of Medicine, National Yang-Ming University (W.H.H.S., I.-T.L., K.-W.L.), and School of Medicine, National Defense Medical Center (W.H.H.S.), Taipei - all in Taiwan; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA (X.G., J.I.R., Y.-D.I.C.); the Division of Cardiology, Department of Medicine, Molecular Physiology Institute, School of Medicine, Duke University, Durham, NC (W.E.K., S.H.S.); the Department of Clinical Biochemistry, Rigshospitalet (A.B.W., B.G.N., A.T.-H.), the Copenhagen General Population Study (B.G.N., A.T.-H.) and Department of Clinical Biochemistry (B.G.N.), Herlev and Gentofte Hospital, and the Copenhagen City Heart Study, Frederiksberg Hospital, Copenhagen University Hospital, and Faculty of Health and Medical Sciences, University of Copenhagen (B.G.N., A.T.-H.) - all in Copenhagen; and TNO Metabolic Health Research, Gaubius Laboratory, Leiden, the Netherlands (A.M.H., H.M.G.P.).

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http://dx.doi.org/10.1056/NEJMoa1612790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800308PMC
July 2017

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.

Authors:
Louise V Wain Nick Shrine María Soler Artigas A Mesut Erzurumluoglu Boris Noyvert Lara Bossini-Castillo Ma'en Obeidat Amanda P Henry Michael A Portelli Robert J Hall Charlotte K Billington Tracy L Rimington Anthony G Fenech Catherine John Tineka Blake Victoria E Jackson Richard J Allen Bram P Prins Archie Campbell David J Porteous Marjo-Riitta Jarvelin Matthias Wielscher Alan L James Jennie Hui Nicholas J Wareham Jing Hua Zhao James F Wilson Peter K Joshi Beate Stubbe Rajesh Rawal Holger Schulz Medea Imboden Nicole M Probst-Hensch Stefan Karrasch Christian Gieger Ian J Deary Sarah E Harris Jonathan Marten Igor Rudan Stefan Enroth Ulf Gyllensten Shona M Kerr Ozren Polasek Mika Kähönen Ida Surakka Veronique Vitart Caroline Hayward Terho Lehtimäki Olli T Raitakari David M Evans A John Henderson Craig E Pennell Carol A Wang Peter D Sly Emily S Wan Robert Busch Brian D Hobbs Augusto A Litonjua David W Sparrow Amund Gulsvik Per S Bakke James D Crapo Terri H Beaty Nadia N Hansel Rasika A Mathias Ingo Ruczinski Kathleen C Barnes Yohan Bossé Philippe Joubert Maarten van den Berge Corry-Anke Brandsma Peter D Paré Don D Sin David C Nickle Ke Hao Omri Gottesman Frederick E Dewey Shannon E Bruse David J Carey H Lester Kirchner Stefan Jonsson Gudmar Thorleifsson Ingileif Jonsdottir Thorarinn Gislason Kari Stefansson Claudia Schurmann Girish Nadkarni Erwin P Bottinger Ruth J F Loos Robin G Walters Zhengming Chen Iona Y Millwood Julien Vaucher Om P Kurmi Liming Li Anna L Hansell Chris Brightling Eleftheria Zeggini Michael H Cho Edwin K Silverman Ian Sayers Gosia Trynka Andrew P Morris David P Strachan Ian P Hall Martin D Tobin

Nat Genet 2017 Mar 6;49(3):416-425. Epub 2017 Feb 6.

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/ng.3787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326681PMC
March 2017

Reply to: Reproducibility and Visual Inspection of Data.

Biol Psychiatry 2016 09 26;80(5):e37-8. Epub 2015 Nov 26.

Department of Genetics, Rutgers University, Piscataway, New Jersey; Department of Statistics and Biostatistics, Rutgers University, Piscataway, New Jersey; Human Genetics Institute of New Jersey, Rutgers University, Piscataway, New Jersey.

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http://dx.doi.org/10.1016/j.biopsych.2015.11.011DOI Listing
September 2016

CCR2, CCR5, and CXCL12 variation and HIV/AIDS in Papua New Guinea.

Infect Genet Evol 2015 Dec 28;36:165-173. Epub 2015 Sep 28.

Center for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, OH, USA.

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http://dx.doi.org/10.1016/j.meegid.2015.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644711PMC
December 2015

Acrolein-exposed normal human lung fibroblasts in vitro: cellular senescence, enhanced telomere erosion, and degradation of Werner's syndrome protein.

Environ Health Perspect 2014 Sep 18;122(9):955-62. Epub 2014 Apr 18.

Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of New Mexico and New Mexico VA Health Care System, Albuquerque, New Mexico, USA.

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http://dx.doi.org/10.1289/ehp.1306911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154210PMC
September 2014

Native American ancestry, lung function, and COPD in Costa Ricans.

Chest 2014 Apr;145(4):704-710

Division of Pulmonary Medicine, Allergy and Immunology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.

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http://dx.doi.org/10.1378/chest.13-1308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971968PMC
April 2014

Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke-induced DNA damage and cytotoxicity.

Free Radic Biol Med 2014 Mar 4;68:80-6. Epub 2013 Dec 4.

Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of New Mexico, Albuquerque, NM 87131, USA; New Mexico VA Health Care System, Albuquerque, NM 87108, USA; COPD Program, Lovelace Respiratory Research Institute, Albuquerque, NM 87108, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2013.11.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941192PMC
March 2014

Chronological changes in microRNA expression in the developing human brain.

PLoS One 2013 16;8(4):e60480. Epub 2013 Apr 16.

Department of Genetics, Rutgers University, Piscataway, New Jersey, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0060480PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628885PMC
November 2013

Softwares and methods for estimating genetic ancestry in human populations.

Hum Genomics 2013 Jan 5;7. Epub 2013 Jan 5.

Lovelace Respiratory Research Institute, Albuquerque, NM 87108, USA.

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http://dx.doi.org/10.1186/1479-7364-7-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542037PMC
January 2013

Improvements to bead-based oligonucleotide ligation SNP genotyping assays.

Biotechniques 2008 Nov;45(5):559-71

Department of Genetics, Rutgers University, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.2144/000112960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987951PMC
November 2008