Shann-Ching Chen

Shann-Ching Chen

UNVERIFIED PROFILE

Are you Shann-Ching Chen?   Register this Author

Register author
Shann-Ching Chen

Shann-Ching Chen

Publications by authors named "Shann-Ching Chen"

Are you Shann-Ching Chen?   Register this Author

28Publications

1040Reads

7Profile Views

Whole-genome sequencing of Atacama skeleton shows novel mutations linked with dysplasia.

Genome Res 2018 04 22;28(4):423-431. Epub 2018 Mar 22.

Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Stanford University, Stanford, California 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.223693.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880234PMC
April 2018

Haploinsufficient loss of multiple 5q genes may fine-tune Wnt signaling in del(5q) therapy-related myeloid neoplasms.

Blood 2015 Dec 13;126(26):2899-901. Epub 2015 Nov 13.

Department of Medicine, Comprehensive Cancer Center, University of Chicago, Chicago, IL.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2015-10-673228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692148PMC
December 2015

LIN28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans.

Genes Dev 2015 May 8;29(10):1074-86. Epub 2015 May 8.

Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, Massachusetts 02115, USA; Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA; Harvard Stem Cell Institute, Boston, Massachusetts 02115, USA; Howard Hughes Medical Institute, Boston, Massachusetts 02138, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.256693.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441054PMC
May 2015

Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia.

Nature 2014 Sep 20;513(7519):512-6. Epub 2014 Jul 20.

Department of Pediatrics and Benniof Children's Hospital, University of California, San Francisco, California 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature13495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213126PMC
September 2014

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia.

N Engl J Med 2014 Sep;371(11):1005-15

From the Departments of Pathology (K.G.R., D.P.-T., Y.-L.Y., K. McCastlain, G.S., J.M., S.-C.C., J.C., N.S.-M., I.I., J.W., J.R.D., C.G.M.), Computational Biology and Bioinformatics (Y.L., J.B., M.R., E.H., P.G., P.N., G.W., X.C., J.Z.), Biostatistics (D.P., C.C.), Pharmaceutical Sciences (S.W.P., M.V.R., W.E.E.), and Oncology (C.-H.P., S.J.), the Pediatric Cancer Genome Project (Y.L., L.D., C.L., M.R., J.E., J.C., K.B., R.S.F., E.H., P.G., P.N., G.W., X.C., D.Y., B.V., H.M., M.V.R., W.E.E., E.M., R.K.W., J.R.D., J.Z., C.G.M.), and Cytogenetics Shared Resource (M.V.), St. Jude Children's Research Hospital, Memphis, TN; the University of New Mexico Cancer Center and School of Medicine, Albuquerque (R.C.H., I-M.C., C.L.W.); the Genome Institute at Washington University (L.D., C.L., R.S.F., E.M., R.K.W.), the Department of Genetics, Washington University School of Medicine (L.D., C.L., R.S.F., E.M., R.K.W.), and Siteman Cancer Center, Washington University (E.M., R.K.W.) - all in St. Louis; Epidemiology and Health Policy Research, College of Medicine, University of Florida, Gainesville (M.D.); the Research Institute at Nationwide Children's Hospital (S.R., A.S., J.M.G.-F.), the Department of Pathology, College of Medicine, Ohio State University (N.A.H.), and Ohio State University Comprehensive Cancer Center (G.M., C.D.B., K. Mrózek, J.K.) - all in Columbus, OH; the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas (N.J.W.), Scott and White Hospitals and Clinics and Texas A&M Health Science Center, Temple (G.G.), the University of Texas Health Science Center San Antonio, San Antonio (M.F.-J.), and the Departments of Leukemia and Stem Cell Transplantation, Division of Cancer Medicine, University of Texas M.D. Anderson Cancer Center, Houston (S.M.K., M.K.) - all in Texas; Maine Children's Cancer Program, Scarborough (E.C.L.); New York University Cancer Institute, New York (W.L.C.), and the Department of Medicine (Oncology), Albert Einstein

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1403088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191900PMC
September 2014

Mechanical feedback through E-cadherin promotes direction sensing during collective cell migration.

Cell 2014 May;157(5):1146-59

Department of Biological Chemistry, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA; Molecular, Cellular and Developmental Biology Department, University of California, Santa Barbara, Santa Barbara, CA 93106-9625, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00928674140047
Publisher Site
http://dx.doi.org/10.1016/j.cell.2014.03.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118667PMC
May 2014

Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential.

J Exp Med 2014 Apr 31;211(4):701-13. Epub 2014 Mar 31.

Department of Hematology and 2 Department of Pathology, Division of Experimental Hematology, St. Jude Children's Research Hospital, Memphis, TN 38105.

View Article

Download full-text PDF

Source
http://www.jem.org/lookup/doi/10.1084/jem.20122727
Publisher Site
http://dx.doi.org/10.1084/jem.20122727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978278PMC
April 2014

Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness.

Nature 2013 Dec 27;504(7478):143-147. Epub 2013 Nov 27.

Howard Hughes Medical Institute, Department of Pediatrics, and Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, Texas, 75390, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature12830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128640PMC
December 2013

Dominant role of oncogene dosage and absence of tumor suppressor activity in Nras-driven hematopoietic transformation.

Cancer Discov 2013 Sep 3;3(9):993-1001. Epub 2013 Jun 3.

1Department of Pediatrics and 2Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California; 3Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, 4Department of Biology, David H. Koch Institute for Integrative Cancer Research and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts; 5Department of Pathology, Institute for Genomics and Systems Biology, 6Ben May Department for Cancer Research, 7Section of Hematology/Oncology and Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 8Department of Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, Michigan; and 9Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2159-8290.CD-13-0096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770749PMC
September 2013

Association of the variations in the HSD3β gene with primary aldosteronism.

J Hypertens 2013 Jul;31(7):1396-405; discussion 1405

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0b013e328360ef3cDOI Listing
July 2013

Automated image analysis of protein localization in budding yeast.

Bioinformatics 2007 Jul;23(13):i66-71

Center for Bioimage Informatics, Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btm206DOI Listing
July 2007

oGNM: online computation of structural dynamics using the Gaussian Network Model.

Nucleic Acids Res 2006 Jul;34(Web Server issue):W24-31

Department of Computational Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkl084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538811PMC
July 2006

A graphical model approach to automated classification of protein subcellular location patterns in multi-cell images.

BMC Bioinformatics 2006 Feb 23;7:90. Epub 2006 Feb 23.

Department of Biomedical Engineering and Center for Bioimage Informatics, Carnegie Mellon University, Pittsburgh, PA 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2105-7-90DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489953PMC
February 2006

Mining frequent patterns in protein structures: a study of protease families.

Bioinformatics 2004 Aug;20 Suppl 1:i77-85

Center for Computational Biology and Bioinformatics, Department of Molecular Genetics and Biochemistry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/bth912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1201446PMC
August 2004