Shamil Sunyaev

Shamil Sunyaev

UNVERIFIED PROFILE

Are you Shamil Sunyaev?   Register this Author

Register author
Shamil Sunyaev

Shamil Sunyaev

Publications by authors named "Shamil Sunyaev"

Are you Shamil Sunyaev?   Register this Author

100Publications

3187Reads

16Profile Views

PINES: phenotype-informed tissue weighting improves prediction of pathogenic noncoding variants.

Genome Biol 2018 10 25;19(1):173. Epub 2018 Oct 25.

Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

View Article

Download full-text PDF

Source
https://genomebiology.biomedcentral.com/articles/10.1186/s13
Publisher Site
http://dx.doi.org/10.1186/s13059-018-1546-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203199PMC
October 2018

A literature review at genome scale: improving clinical variant assessment.

Genet Med 2018 09 1;20(9):936-941. Epub 2018 Feb 1.

Division of Genetics, Brigham and Women's Hospital, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/gim.2017.230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070443PMC
September 2018

Bayesian inference of negative and positive selection in human cancers.

Nat Genet 2017 Dec 6;49(12):1785-1788. Epub 2017 Nov 6.

Department of Medicine, Division of Genetics, Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3987DOI Listing
December 2017

Excess of Deleterious Mutations around HLA Genes Reveals Evolutionary Cost of Balancing Selection.

Mol Biol Evol 2016 10 28;33(10):2555-64. Epub 2016 Jun 28.

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School Program in Medical and Population Genetics, The Broad Institute, Cambridge, MA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/molbev/msw127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026253PMC
October 2016

Increasing Generality and Power of Rare-Variant Tests by Utilizing Extended Pedigrees.

Am J Hum Genet 2016 Oct 22;99(4):846-859. Epub 2016 Sep 22.

Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2016.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065687PMC
October 2016

Leveraging Distant Relatedness to Quantify Human Mutation and Gene-Conversion Rates.

Am J Hum Genet 2015 Dec 12;97(6):775-89. Epub 2015 Nov 12.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2015.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678427PMC
December 2015

Dominance of Deleterious Alleles Controls the Response to a Population Bottleneck.

PLoS Genet 2015 Aug 28;11(8):e1005436. Epub 2015 Aug 28.

Division of Genetics, Brigham and Women's Hospital, Boston, Massachusetts, United States of America; Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1005436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552954PMC
August 2015

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction.

Nature 2015 Feb 10;518(7537):102-6. Epub 2014 Dec 10.

1] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA. [2] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA. [3] Department of Medicine, Harvard Medical School, Boston, Massachusetts 02114, USA. [4] Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA.

View Article

Download full-text PDF

Source
http://kooperberg.fhcrc.org/papers/2015do.pdf
Web Search
http://www.nature.com/doifinder/10.1038/nature13917
Publisher Site
http://dx.doi.org/10.1038/nature13917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319990PMC
February 2015

No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans.

Nat Genet 2015 Feb 12;47(2):126-31. Epub 2015 Jan 12.

1] Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA. [3] Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310772PMC
February 2015

Integrative analysis of 111 reference human epigenomes.

Nature 2015 Feb;518(7539):317-30

1] Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, Massachusetts 02139, USA. [2] The Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, Massachusetts 02142, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature14248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530010PMC
February 2015

Cell-of-origin chromatin organization shapes the mutational landscape of cancer.

Nature 2015 Feb;518(7539):360-364

Division of Genetics, Department of Medicine, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, 02115.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature14221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405175PMC
February 2015

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

Authors:
Catherine A Brownstein Alan H Beggs Nils Homer Barry Merriman Timothy W Yu Katherine C Flannery Elizabeth T DeChene Meghan C Towne Sarah K Savage Emily N Price Ingrid A Holm Lovelace J Luquette Elaine Lyon Joseph Majzoub Peter Neupert David McCallie Peter Szolovits Huntington F Willard Nancy J Mendelsohn Renee Temme Richard S Finkel Sabrina W Yum Livija Medne Shamil R Sunyaev Ivan Adzhubey Christopher A Cassa Paul I W de Bakker Hatice Duzkale Piotr Dworzyński William Fairbrother Laurent Francioli Birgit H Funke Monica A Giovanni Robert E Handsaker Kasper Lage Matthew S Lebo Monkol Lek Ignaty Leshchiner Daniel G MacArthur Heather M McLaughlin Michael F Murray Tune H Pers Paz P Polak Soumya Raychaudhuri Heidi L Rehm Rachel Soemedi Nathan O Stitziel Sara Vestecka Jochen Supper Claudia Gugenmus Bernward Klocke Alexander Hahn Max Schubach Mortiz Menzel Saskia Biskup Peter Freisinger Mario Deng Martin Braun Sven Perner Richard J H Smith Janeen L Andorf Jian Huang Kelli Ryckman Val C Sheffield Edwin M Stone Thomas Bair E Ann Black-Ziegelbein Terry A Braun Benjamin Darbro Adam P DeLuca Diana L Kolbe Todd E Scheetz Aiden E Shearer Rama Sompallae Kai Wang Alexander G Bassuk Erik Edens Katherine Mathews Steven A Moore Oleg A Shchelochkov Pamela Trapane Aaron Bossler Colleen A Campbell Jonathan W Heusel Anne Kwitek Tara Maga Karin Panzer Thomas Wassink Douglas Van Daele Hela Azaiez Kevin Booth Nic Meyer Michael M Segal Marc S Williams Gerard Tromp Peter White Donald Corsmeier Sara Fitzgerald-Butt Gail Herman Devon Lamb-Thrush Kim L McBride David Newsom Christopher R Pierson Alexander T Rakowsky Aleš Maver Luca Lovrečić Anja Palandačić Borut Peterlin Ali Torkamani Anna Wedell Mikael Huss Andrey Alexeyenko Jessica M Lindvall Måns Magnusson Daniel Nilsson Henrik Stranneheim Fulya Taylan Christian Gilissen Alexander Hoischen Bregje van Bon Helger Yntema Marcel Nelen Weidong Zhang Jason Sager Lu Zhang Kathryn Blair Deniz Kural Michael Cariaso Greg G Lennon Asif Javed Saloni Agrawal Pauline C Ng Komal S Sandhu Shuba Krishna Vamsi Veeramachaneni Ofer Isakov Eran Halperin Eitan Friedman Noam Shomron Gustavo Glusman Jared C Roach Juan Caballero Hannah C Cox Denise Mauldin Seth A Ament Lee Rowen Daniel R Richards F Anthony San Lucas Manuel L Gonzalez-Garay C Thomas Caskey Yu Bai Ying Huang Fang Fang Yan Zhang Zhengyuan Wang Jorge Barrera Juan M Garcia-Lobo Domingo González-Lamuño Javier Llorca Maria C Rodriguez Ignacio Varela Martin G Reese Francisco M De La Vega Edward Kiruluta Michele Cargill Reece K Hart Jon M Sorenson Gholson J Lyon David A Stevenson Bruce E Bray Barry M Moore Karen Eilbeck Mark Yandell Hongyu Zhao Lin Hou Xiaowei Chen Xiting Yan Mengjie Chen Cong Li Can Yang Murat Gunel Peining Li Yong Kong Austin C Alexander Zayed I Albertyn Kym M Boycott Dennis E Bulman Paul M K Gordon A Micheil Innes Bartha M Knoppers Jacek Majewski Christian R Marshall Jillian S Parboosingh Sarah L Sawyer Mark E Samuels Jeremy Schwartzentruber Isaac S Kohane David M Margulies

Genome Biol 2014 Mar 25;15(3):R53. Epub 2014 Mar 25.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/gb-2014-15-3-r53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073084PMC
March 2014

Reduced local mutation density in regulatory DNA of cancer genomes is linked to DNA repair.

Nat Biotechnol 2014 Jan 15;32(1):71-5. Epub 2013 Dec 15.

1] Division of Genetics, Department of Medicine, Brigham & Women's Hospital, Boston, Massachusetts, USA. [2] Harvard Medical School, Boston, Massachusetts, USA. [3] The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nbt.2778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116484PMC
January 2014

Evaluating empirical bounds on complex disease genetic architecture.

Nat Genet 2013 Dec 20;45(12):1418-27. Epub 2013 Oct 20.

1] Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. [2] Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. [3] Program in Biophysics, Graduate School of Arts and Sciences, Harvard University, Cambridge, Massachusetts, USA. [4].

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.2804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158716PMC
December 2013

Systems biology and the analysis of genetic variation.

Curr Opin Genet Dev 2013 Dec 28;23(6):599-601. Epub 2013 Nov 28.

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gde.2013.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116483PMC
December 2013

Sequencing studies in human genetics: design and interpretation.

Nat Rev Genet 2013 Jul 11;14(7):460-70. Epub 2013 Jun 11.

Center for Human Genome Variation, Duke University School of Medicine, 308 Research Drive, Box 91009, LSRC B Wing, Room 330, Durham, North Carolina 27708, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrg3455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117319PMC
July 2013

Impact of deleterious passenger mutations on cancer progression.

Proc Natl Acad Sci U S A 2013 Feb 6;110(8):2910-5. Epub 2013 Feb 6.

Graduate Program in Biophysics, Harvard University, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1213968110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581883PMC
February 2013

Predicting functional effect of human missense mutations using PolyPhen-2.

Curr Protoc Hum Genet 2013 Jan;Chapter 7:Unit7.20

Division of Genetics, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/0471142905.hg0720s76DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480630PMC
January 2013

Network-based inference from complex proteomic mixtures using SNIPE.

Bioinformatics 2012 Dec 11;28(23):3115-22. Epub 2012 Oct 11.

Division of Genetics, Brigham and Women's Hospital, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/bts594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509492PMC
December 2012

Inferring causality and functional significance of human coding DNA variants.

Authors:
Shamil R Sunyaev

Hum Mol Genet 2012 Oct 17;21(R1):R10-7. Epub 2012 Sep 17.

Genetics Division, Brigham and Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/dds385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459643PMC
October 2012

The mystery of missing heritability: Genetic interactions create phantom heritability.

Proc Natl Acad Sci U S A 2012 Jan 5;109(4):1193-8. Epub 2012 Jan 5.

Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1119675109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268279PMC
January 2012

Computational and statistical approaches to analyzing variants identified by exome sequencing.

Genome Biol 2011 Sep 14;12(9):227. Epub 2011 Sep 14.

Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://genomebiology.biomedcentral.com/articles/10.1186/gb-2
Publisher Site
http://dx.doi.org/10.1186/gb-2011-12-9-227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308043PMC
September 2011

Assigning spectrum-specific P-values to protein identifications by mass spectrometry.

Bioinformatics 2011 Apr 23;27(8):1128-34. Epub 2011 Feb 23.

Division of Genetics, Brigham and Women's Hospital, Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btr089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072553PMC
April 2011

Human allelic variation: perspective from protein function, structure, and evolution.

Curr Opin Struct Biol 2010 Jun;20(3):342-50

Division of Genetics, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.sbi.2010.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921592PMC
June 2010

Pooled association tests for rare variants in exon-resequencing studies.

Am J Hum Genet 2010 Jun 13;86(6):832-8. Epub 2010 May 13.

Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2010.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032073PMC
June 2010

Triplet repeat length bias and variation in the human transcriptome.

Proc Natl Acad Sci U S A 2009 Oct 17;106(40):17095-100. Epub 2009 Sep 17.

Department of Biomedical Engineering and Center for Advanced Biotechnology, Boston University, Boston, MA 02215, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0907112106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746125PMC
October 2009

Human mutation rate associated with DNA replication timing.

Nat Genet 2009 Apr 15;41(4):393-5. Epub 2009 Mar 15.

Department of Genome Sciences and Medicine, University of Washington, Seattle, WA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914101PMC
April 2009

SNP2RFLP: a computational tool to facilitate genetic mapping using benchtop analysis of SNPs.

Mamm Genome 2008 Oct-Dec;19(10-12):687-90. Epub 2008 Oct 29.

Department of Biology, Brigham Young University, Provo, UT 84602, USA.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00335-008-9149-2
Publisher Site
http://dx.doi.org/10.1007/s00335-008-9149-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001109PMC
March 2009

Power of deep, all-exon resequencing for discovery of human trait genes.

Proc Natl Acad Sci U S A 2009 Mar 6;106(10):3871-6. Epub 2009 Feb 6.

Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0812824106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656172PMC
March 2009

Adaptive mutations in the JC virus protein capsid are associated with progressive multifocal leukoencephalopathy (PML).

PLoS Genet 2009 Feb 6;5(2):e1000368. Epub 2009 Feb 6.

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1000368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629573PMC
February 2009

Hypermutable non-synonymous sites are under stronger negative selection.

PLoS Genet 2008 11 28;4(11):e1000281. Epub 2008 Nov 28.

Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

View Article

Download full-text PDF

Source
https://dx.plos.org/10.1371/journal.pgen.1000281
Publisher Site
http://dx.doi.org/10.1371/journal.pgen.1000281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583910PMC
November 2008

Protein identification pipeline for the homology-driven proteomics.

J Proteomics 2008 Aug 12;71(3):346-56. Epub 2008 Jul 12.

Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jprot.2008.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644553PMC
August 2008

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

J Proteome Res 2008 Jan 23;7(1):311-8. Epub 2007 Nov 23.

Department of Biology, University of Vermont, Burlington, Vermont 05405, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/pr0701254DOI Listing
January 2008

Shifting paradigm of association studies: value of rare single-nucleotide polymorphisms.

Am J Hum Genet 2008 Jan;82(1):100-12

Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2007.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253956PMC
January 2008

Analysis of sequence conservation at nucleotide resolution.

PLoS Comput Biol 2007 Dec 14;3(12):e254. Epub 2007 Nov 14.

Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pcbi.0030254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2230682PMC
December 2007

Toxicity of influenza A virus matrix protein 2 for mammalian cells is associated with its intrinsic proton-channeling activity.

Cell Cycle 2007 Aug 12;6(16):2043-7. Epub 2007 Jun 12.

Cure Lab, Inc., Canton, Massachusetts 02021, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cc.6.16.4564DOI Listing
August 2007

Sequence similarity-driven proteomics in organisms with unknown genomes by LC-MS/MS and automated de novo sequencing.

Proteomics 2007 Jul;7(14):2318-29

Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pmic.200700003DOI Listing
July 2007

Widely distributed noncoding purifying selection in the human genome.

Proc Natl Acad Sci U S A 2007 Jul 17;104(30):12410-5. Epub 2007 Jul 17.

Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0705140104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1941483PMC
July 2007

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

Authors:
Ewan Birney John A Stamatoyannopoulos Anindya Dutta Roderic Guigó Thomas R Gingeras Elliott H Margulies Zhiping Weng Michael Snyder Emmanouil T Dermitzakis Robert E Thurman Michael S Kuehn Christopher M Taylor Shane Neph Christoph M Koch Saurabh Asthana Ankit Malhotra Ivan Adzhubei Jason A Greenbaum Robert M Andrews Paul Flicek Patrick J Boyle Hua Cao Nigel P Carter Gayle K Clelland Sean Davis Nathan Day Pawandeep Dhami Shane C Dillon Michael O Dorschner Heike Fiegler Paul G Giresi Jeff Goldy Michael Hawrylycz Andrew Haydock Richard Humbert Keith D James Brett E Johnson Ericka M Johnson Tristan T Frum Elizabeth R Rosenzweig Neerja Karnani Kirsten Lee Gregory C Lefebvre Patrick A Navas Fidencio Neri Stephen C J Parker Peter J Sabo Richard Sandstrom Anthony Shafer David Vetrie Molly Weaver Sarah Wilcox Man Yu Francis S Collins Job Dekker Jason D Lieb Thomas D Tullius Gregory E Crawford Shamil Sunyaev William S Noble Ian Dunham France Denoeud Alexandre Reymond Philipp Kapranov Joel Rozowsky Deyou Zheng Robert Castelo Adam Frankish Jennifer Harrow Srinka Ghosh Albin Sandelin Ivo L Hofacker Robert Baertsch Damian Keefe Sujit Dike Jill Cheng Heather A Hirsch Edward A Sekinger Julien Lagarde Josep F Abril Atif Shahab Christoph Flamm Claudia Fried Jörg Hackermüller Jana Hertel Manja Lindemeyer Kristin Missal Andrea Tanzer Stefan Washietl Jan Korbel Olof Emanuelsson Jakob S Pedersen Nancy Holroyd Ruth Taylor David Swarbreck Nicholas Matthews Mark C Dickson Daryl J Thomas Matthew T Weirauch James Gilbert Jorg Drenkow Ian Bell XiaoDong Zhao K G Srinivasan Wing-Kin Sung Hong Sain Ooi Kuo Ping Chiu Sylvain Foissac Tyler Alioto Michael Brent Lior Pachter Michael L Tress Alfonso Valencia Siew Woh Choo Chiou Yu Choo Catherine Ucla Caroline Manzano Carine Wyss Evelyn Cheung Taane G Clark James B Brown Madhavan Ganesh Sandeep Patel Hari Tammana Jacqueline Chrast Charlotte N Henrichsen Chikatoshi Kai Jun Kawai Ugrappa Nagalakshmi Jiaqian Wu Zheng Lian Jin Lian Peter Newburger Xueqing Zhang Peter Bickel John S Mattick Piero Carninci Yoshihide Hayashizaki Sherman Weissman Tim Hubbard Richard M Myers Jane Rogers Peter F Stadler Todd M Lowe Chia-Lin Wei Yijun Ruan Kevin Struhl Mark Gerstein Stylianos E Antonarakis Yutao Fu Eric D Green Ulaş Karaöz Adam Siepel James Taylor Laura A Liefer Kris A Wetterstrand Peter J Good Elise A Feingold Mark S Guyer Gregory M Cooper George Asimenos Colin N Dewey Minmei Hou Sergey Nikolaev Juan I Montoya-Burgos Ari Löytynoja Simon Whelan Fabio Pardi Tim Massingham Haiyan Huang Nancy R Zhang Ian Holmes James C Mullikin Abel Ureta-Vidal Benedict Paten Michael Seringhaus Deanna Church Kate Rosenbloom W James Kent Eric A Stone Serafim Batzoglou Nick Goldman Ross C Hardison David Haussler Webb Miller Arend Sidow Nathan D Trinklein Zhengdong D Zhang Leah Barrera Rhona Stuart David C King Adam Ameur Stefan Enroth Mark C Bieda Jonghwan Kim Akshay A Bhinge Nan Jiang Jun Liu Fei Yao Vinsensius B Vega Charlie W H Lee Patrick Ng Atif Shahab Annie Yang Zarmik Moqtaderi Zhou Zhu Xiaoqin Xu Sharon Squazzo Matthew J Oberley David Inman Michael A Singer Todd A Richmond Kyle J Munn Alvaro Rada-Iglesias Ola Wallerman Jan Komorowski Joanna C Fowler Phillippe Couttet Alexander W Bruce Oliver M Dovey Peter D Ellis Cordelia F Langford David A Nix Ghia Euskirchen Stephen Hartman Alexander E Urban Peter Kraus Sara Van Calcar Nate Heintzman Tae Hoon Kim Kun Wang Chunxu Qu Gary Hon Rosa Luna Christopher K Glass M Geoff Rosenfeld Shelley Force Aldred Sara J Cooper Anason Halees Jane M Lin Hennady P Shulha Xiaoling Zhang Mousheng Xu Jaafar N S Haidar Yong Yu Yijun Ruan Vishwanath R Iyer Roland D Green Claes Wadelius Peggy J Farnham Bing Ren Rachel A Harte Angie S Hinrichs Heather Trumbower Hiram Clawson Jennifer Hillman-Jackson Ann S Zweig Kayla Smith Archana Thakkapallayil Galt Barber Robert M Kuhn Donna Karolchik Lluis Armengol Christine P Bird Paul I W de Bakker Andrew D Kern Nuria Lopez-Bigas Joel D Martin Barbara E Stranger Abigail Woodroffe Eugene Davydov Antigone Dimas Eduardo Eyras Ingileif B Hallgrímsdóttir Julian Huppert Michael C Zody Gonçalo R Abecasis Xavier Estivill Gerard G Bouffard Xiaobin Guan Nancy F Hansen Jacquelyn R Idol Valerie V B Maduro Baishali Maskeri Jennifer C McDowell Morgan Park Pamela J Thomas Alice C Young Robert W Blakesley Donna M Muzny Erica Sodergren David A Wheeler Kim C Worley Huaiyang Jiang George M Weinstock Richard A Gibbs Tina Graves Robert Fulton Elaine R Mardis Richard K Wilson Michele Clamp James Cuff Sante Gnerre David B Jaffe Jean L Chang Kerstin Lindblad-Toh Eric S Lander Maxim Koriabine Mikhail Nefedov Kazutoyo Osoegawa Yuko Yoshinaga Baoli Zhu Pieter J de Jong
June 2007