Publications by authors named "Shalender Bhasin"

99Publications

A Multifactorial Trial to Prevent Serious Fall Injuries. Reply.

N Engl J Med 2020 10;383(14):1395-1396

David Geffen School of Medicine at UCLA, Los Angeles, CA.

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http://dx.doi.org/10.1056/NEJMc2026944DOI Listing
October 2020

Markers of Iron Flux during Testosterone-Mediated Erythropoiesis in Older Men with Unexplained or Iron-Deficiency Anemia.

J Clin Endocrinol Metab 2020 Nov;105(11)

Division of Endocrinology, Diabetes, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1210/clinem/dgaa521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500468PMC
November 2020

The role of iron in mediating testosterone's effects on erythropoiesis in mice.

FASEB J 2020 Jul 15. Epub 2020 Jul 15.

Research Program in Men's Health: Aging and Metabolism, The Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1096/fj.202000920RRDOI Listing
July 2020

A Randomized Trial of a Multifactorial Strategy to Prevent Serious Fall Injuries.

N Engl J Med 2020 07;383(2):129-140

From the Boston Claude D. Pepper Older Americans Independence Center, Research Program in Men's Health: Aging and Metabolism (S. Bhasin, N.K.L., S. Basaria, T.W.S., T.G.T., L.G., B.F.B., R.E.), Brigham and Women's Hospital (S. Bhasin, N.K.L., S. Basaria, P.C.D., T.W.S., T.G.T., P.G., M.B.C., L.G., B.F.B., R.E.), Marcus Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School (T.G.T.), and the University of Massachusetts Boston (P.G.), Boston, and Meyers Primary Care Institute (joint endeavor of Reliant Medical Group, Fallon Health, and University of Massachusetts Medical School), Worcester (J.H.G.); the Yale Claude D. Pepper Older Americans Independence Center (T.M.G., P.C., K.A., J.M.M., E.A.S., D.B.), the Yale Center for Analytical Sciences (E.J.G., J.D., D.E., C.L., H.R., C.M., H.A., P.P.), and the Section of Geriatrics, Department of Internal Medicine, Yale School of Medicine (T.M.G., H.A.), Yale University, New Haven, CT; the Multicampus Program in Geriatric Medicine and Gerontology, David Geffen School of Medicine at UCLA (D.B.R., D.A.G.), the Geriatric Research, Education and Clinical Center, Veterans Affairs Greater Los Angeles Healthcare System (D.A.G.), and the UCLA Claude D. Pepper Older Americans Independence Center (D.B.R, D.A.G.), Los Angeles, and HealthCare Partners, El Segundo (J.R.) - all in California; the School of Nursing, University of Minnesota, Minneapolis (S.M.M.), and Essentia Health, Duluth (S.C.W.) - both in Minnesota; Wake Forest University, School of Medicine, Winston-Salem, NC (M.E.M., P.W.D.); the University of Miami Health System, Miami (M.F.); the Pittsburgh Claude D. Pepper Older Americans Independence Center, Division of Geriatrics and Gerontology, University of Pittsburgh, Pittsburgh (S.L.G., N.M.R.); the University of Michigan, Ann Arbor (N.A., J.W.); Icahn School of Medicine at Mount Sinai, New York (F.K., A.L.S.); the UTMB Claude D. Pepper Older Americans Independence Center, Sealy Center on Aging, University of Texas Medical Branch, Galveston (E.V.); Johns Hopkins University (A.W.W., C.B.) and the University of Maryland School of Medicine (J.M.), Baltimore, and the National Institute on Aging, Bethesda (R.C.-A.) - all in Maryland; and the University of Iowa, Iowa City (R.B.W., C.C.).

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http://dx.doi.org/10.1056/NEJMoa2002183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7421468PMC
July 2020

Application of Cut-Points for Low Muscle Strength and Lean Mass in Mobility-Limited Older Adults.

J Am Geriatr Soc 2020 Jul 7;68(7):1445-1453. Epub 2020 Jul 7.

Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center, Tufts University, Boston, Massachusetts.

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http://dx.doi.org/10.1111/jgs.16525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440655PMC
July 2020

Reply to: "Zooming" in the Anterior Thigh Muscle for the Diagnosis of Sarcopenia.

J Am Geriatr Soc 2020 Aug 13;68(8):1879-1880. Epub 2020 Jun 13.

San Francisco Coordinating Center, California Pacific Medical Center Research Institute, San Francisco, California.

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http://dx.doi.org/10.1111/jgs.16571DOI Listing
August 2020

Differential effects of testosterone on circulating neutrophils, monocytes, and platelets in men: Findings from two trials.

Andrology 2020 09 2;8(5):1324-1331. Epub 2020 Jul 2.

Research Program in Men's Health: Aging and Metabolism, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/andr.12834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484244PMC
September 2020

Associations of Endogenous Sex Hormones with Carotid Plaque Burden and Characteristics in Midlife Women.

J Clin Endocrinol Metab 2020 Apr;105(4)

Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1210/clinem/dgz327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077951PMC
April 2020

Fertility Considerations in Adolescent Klinefelter Syndrome: Current Practice Patterns.

J Clin Endocrinol Metab 2020 Apr;105(4)

Boston University School of Medicine, Department of Urology, Boston Medical Center, Boston, Massachusetts.

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http://dx.doi.org/10.1210/clinem/dgz308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060759PMC
April 2020

Health Outcomes Among Long-term Opioid Users With Testosterone Prescription in the Veterans Health Administration.

JAMA Netw Open 2019 12 2;2(12):e1917141. Epub 2019 Dec 2.

Research Program in Men's Health, Aging and Metabolism, Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamanetworkopen.2019.17141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991198PMC
December 2019

The Stair Climb Power Test as an Efficacy Outcome in Randomized Trials of Function Promoting Therapies in Older Men.

J Gerontol A Biol Sci Med Sci 2020 May;75(6):1167-1175

Research Program in Men's Health, Aging, and Metabolism; Boston Claude D. Pepper Older Americans Independence Center; Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1093/gerona/glz167DOI Listing
May 2020

Analysis of Cre-mediated genetic deletion of in cardiomyocytes of young mice.

Am J Physiol Heart Circ Physiol 2019 07 24;317(1):H201-H212. Epub 2019 May 24.

Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute, Harvard University , Cambridge, Massachusetts.

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https://www.physiology.org/doi/10.1152/ajpheart.00615.2018
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http://dx.doi.org/10.1152/ajpheart.00615.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692736PMC
July 2019

Circulating Biomarkers of Testosterone's Anabolic Effects on Fat-Free Mass.

J Clin Endocrinol Metab 2019 May 23. Epub 2019 May 23.

Section of Men's Health: Aging and Metabolism, Boston Claude D. Pepper Older Americans Independence Center for Function Promoting Therapies, Brigham and Women's Hospital-Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1210/jc.2019-00505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656422PMC
May 2019

The Implications of Reproductive Aging for the Health, Vitality and Economic Welfare of Human Societies.

J Clin Endocrinol Metab 2019 Apr 16. Epub 2019 Apr 16.

Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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https://academic.oup.com/jcem/advance-article/doi/10.1210/jc
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http://dx.doi.org/10.1210/jc.2019-00315DOI Listing
April 2019

Implications of Aging in Plastic Surgery.

Plast Reconstr Surg Glob Open 2019 Jan 14;7(1):e2085. Epub 2019 Jan 14.

Division of Plastic Surgery, Brigham and Women's Hospital, Boston, Mass.

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http://dx.doi.org/10.1097/GOX.0000000000002085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382222PMC
January 2019

Testosterone Treatment of Depressive Disorders in Men: Too Much Smoke, Not Enough High-Quality Evidence.

JAMA Psychiatry 2019 01;76(1):9-10

Columbia University, New York, New York.

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http://dx.doi.org/10.1001/jamapsychiatry.2018.2661DOI Listing
January 2019

The Health Threat Posed by the Hidden Epidemic of Anabolic Steroid Use and Body Image Disorders Among Young Men.

J Clin Endocrinol Metab 2019 04;104(4):1069-1074

Research Program in Men's Health: Aging and Metabolism, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1210/jc.2018-01706DOI Listing
April 2019

Sex Differences in the Prenatal Programming of Adult Metabolic Syndrome by Maternal Androgens.

J Clin Endocrinol Metab 2018 11;103(11):3945-3953

Division of Women's Health, Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1210/jc.2018-01243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182312PMC
November 2018

Effects of an ActRIIB.Fc Ligand Trap on Cardiac Function in Simian Immunodeficiency Virus-Infected Male Rhesus Macaques.

J Endocr Soc 2018 Aug 25;2(8):817-831. Epub 2018 May 25.

Research Program in Men's Health: Aging and Metabolism, Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1210/js.2018-00099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041778PMC
August 2018

Long-Term Testosterone Supplementation in Older Men Attenuates Age-Related Decline in Aerobic Capacity.

J Clin Endocrinol Metab 2018 08;103(8):2861-2869

Research Program in Men's Health: Aging and Metabolism, Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1210/jc.2017-01902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669813PMC
August 2018

Reproductive Hormones and Subclinical Cardiovascular Disease in Midlife Women.

J Clin Endocrinol Metab 2018 08;103(8):3070-3077

Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Denver, Colorado.

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http://dx.doi.org/10.1210/jc.2018-00579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276700PMC
August 2018

Preventing Fractures and Falls: A Limited Role for Calcium and Vitamin D Supplements?

JAMA 2018 04;319(15):1552-1553

Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jama.2018.4023DOI Listing
April 2018

The efficacy and adverse events of testosterone replacement therapy in hypogonadal men: A systematic review and meta-analysis of randomized, placebo-controlled trials.

J Clin Endocrinol Metab 2018 Mar 17. Epub 2018 Mar 17.

Knowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1210/jc.2018-00404DOI Listing
March 2018

Use of testosterone in men infected with human immunodeficiency virus in the veterans healthcare system.

AIDS Care 2018 10 19;30(10):1207-1214. Epub 2018 Mar 19.

a Center for Healthcare Organization and Implementation Research (CHOIR) , ENRM VAMC , Bedford , MA , USA.

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http://dx.doi.org/10.1080/09540121.2018.1447080DOI Listing
October 2018

Corrigendum to "A multi-step, allosteric model of testosterone's binding to sex hormone binding globulin" [Mol. Cell. Endocrinol. 399 (2015) 190-200].

Mol Cell Endocrinol 2017 10;454:167

Section of Endocrinology, Diabetes, and Nutrition, Boston Medical Center, Boston University School of Medicine, Boston, MA 02118, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2017.07.032DOI Listing
October 2017

A Reappraisal of Testosterone's Binding in Circulation: Physiological and Clinical Implications.

Endocr Rev 2017 08;38(4):302-324

Research Program in Men's Health: Aging and Metabolism, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1210/er.2017-00025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287254PMC
August 2017

Response to Letter: "Characteristics of Men Who Report Persistent Sexual Symptoms After Finasteride Use for Hair Loss".

J Clin Endocrinol Metab 2017 06;102(6):2119-2120

Research Program in Men's Health: Aging and Metabolism, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1210/jc.2016-3682DOI Listing
June 2017

Harmonized Reference Ranges for Circulating Testosterone Levels in Men of Four Cohort Studies in the United States and Europe.

J Clin Endocrinol Metab 2017 04;102(4):1161-1173

Research Program in Men's Health, Aging, and Metabolism, Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1210/jc.2016-2935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460736PMC
April 2017

Patterns of testosterone prescription overuse.

Curr Opin Endocrinol Diabetes Obes 2017 Jun;24(3):240-245

aCenter for Healthcare Organization and Implementation Research (CHOIR), ENRM VAMC, Bedford. bDepartment of Health Law, Policy and Management, Boston University School of Public Health, Boston cResearch Program in Men's Health, Aging and Metabolism, Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women's Hospital, Harvard Medical School, Boston dRAND Corporation, Boston, MA eDepartment of Medicine, Section of General Internal Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/MED.0000000000000336DOI Listing
June 2017

Administration of an activin receptor IIB ligand trap protects male juvenile rhesus macaques from simian immunodeficiency virus-associated bone loss.

Bone 2017 04 26;97:209-215. Epub 2017 Jan 26.

Research Program in Men's Health: Aging and Metabolism, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, United States.

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http://dx.doi.org/10.1016/j.bone.2017.01.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985824PMC
April 2017

Who Gets Testosterone? Patient Characteristics Associated with Testosterone Prescribing in the Veteran Affairs System: a Cross-Sectional Study.

J Gen Intern Med 2017 Mar 19;32(3):304-311. Epub 2016 Dec 19.

Center for Healthcare Organization and Implementation Research (CHOIR), ENRM VAMC, Bedford VA Medical Center, 200 Springs Road, Bedford, MA, 01730, USA.

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http://dx.doi.org/10.1007/s11606-016-3940-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331013PMC
March 2017

Effects of Testosterone Replacement on Electrocardiographic Parameters in Men: Findings From Two Randomized Trials.

J Clin Endocrinol Metab 2017 05;102(5):1478-1485

Research Program in Men's Health: Aging and Metabolism, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1210/jc.2016-3669DOI Listing
May 2017

Body Image Disorders and Abuse of Anabolic-Androgenic Steroids Among Men.

JAMA 2017 01;317(1):23-24

Research Program in Men's Health: Aging and Metabolism, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jama.2016.17441DOI Listing
January 2017

Effect of Soy in Men With Type 2 Diabetes Mellitus and Subclinical Hypogonadism: A Randomized Controlled Study.

J Clin Endocrinol Metab 2017 Feb;102(2):425-433

Weill Cornell Medical College Qatar, Education City, Doha, 24144, Qatar.

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http://dx.doi.org/10.1210/jc.2016-2875DOI Listing
February 2017

Effects of Testosterone Supplementation for 3 Years on Muscle Performance and Physical Function in Older Men.

J Clin Endocrinol Metab 2017 02;102(2):583-593

Research Program in Men's Health: Aging and Metabolism, Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1210/jc.2016-2771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413164PMC
February 2017

Characteristics of Men Who Report Persistent Sexual Symptoms After Finasteride Use for Hair Loss.

J Clin Endocrinol Metab 2016 12 23;101(12):4669-4680. Epub 2016 Sep 23.

Research Program in Men's Health: Aging and Metabolism (S.Ba., R.K., G.H., K.P., Z.L., C.S., A.P., T.W.S., S.Bh.), Harvard Medical School, Functional Neuroimaging Laboratory (H.P., E.S.), Department of Radiology, and Section of Urology (M.O.), Brigham and Women's Hospital, Boston, Massachusetts 02115; Department of Neurology (W.W.), Emory University, Atlanta, Georgia 30322; Program on Aging (T.G.T.), Hebrew Senior Life, Roslindale, Massachusetts 02131; Department of Dermatology (J.B.), Boston University School of Medicine, Boston, Massachusetts 02118; Endoceutics (R.G., F.L., A.Y.D.), Quebec City, Canada G1V 4M7; and Department of Pathology (S.A.), Harvard Medical School, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1210/jc.2016-2726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155688PMC
December 2016

Testosterone Treatment and Sexual Function in Older Men With Low Testosterone Levels.

J Clin Endocrinol Metab 2016 08 29;101(8):3096-104. Epub 2016 Jun 29.

Departments of Medicine and Molecular and Cellular Biology (G.R.C.), Division of Diabetes, Endocrinology and Metabolism, Baylor College of Medicine and Baylor St. Luke's Medical Center, Houston, Texas 77030; Department of Biostatistics and Epidemiology (A.J.S.-S., J.T.F., B.Z., X.H., S.S.E.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104; New England Research Institutes, Inc (R.C.R.), Watertown, Massachusetts 02472; Division of Endocrinology (C.W., R.S.S.), Harbor-University of California at Los Angeles Medical Center and Los Angeles Biomedical Research Institute, Torrance, California 90502; Research Program in Men's Health: Aging and Metabolism (S.Bh., S.Ba.), Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115; Geriatric Research, Education, and Clinical Center (A.M.M.), Department of Veterans Affairs Puget Sound Health Care System, and Division of Gerontology & Geriatric Medicine, Department of Internal Medicine, University of Washington School of Medicine, Seattle, Washington 98108-1597; Department of Urology (J.K.P.), Moores Comprehensive Cancer Center, University of California, San Diego, California 92093; Division of Geriatric Medicine (T.M.G.), Yale School of Medicine, New Haven, Connecticut 06510; Division of Endocrinology, Metabolism, and Molecular Medicine (M.E.M.), and Department of Medical Social Sciences (D.C.), Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611; Division of Epidemiology (E.B.-C.), Department of Family and Preventive Medicine, University of California, San Diego School of Medicine, La Jolla, California 92093-0607; Department of Epidemiology (J.A.C.), University of Pittsburgh, Graduate School of Public Health, Pittsburgh, Pennsylvania 15261; Center for Clinical Epidemiology and Biostatistics (D.C., L.G.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104; Divisions of Endocrinology and Geriatrics (

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http://dx.doi.org/10.1210/jc.2016-1645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971331PMC
August 2016

Hypogonadism: Its Prevalence and Diagnosis.

Urol Clin North Am 2016 May;43(2):163-76

Research Program in Men's Health: Aging and Metabolism, The Center for Clinical Investigation, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ucl.2016.01.002DOI Listing
May 2016

Effects of Testosterone on Erythropoiesis in a Female Mouse Model of Anemia of Inflammation.

Endocrinology 2016 07 13;157(7):2937-46. Epub 2016 Apr 13.

Research Program in Men's Health: Aging and Metabolism, Boston Claude D. Pepper Older Americans Independence Center (W.G., S.B.), and Department of Pathology (P.J.S., M.D.F.), Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1210/en.2016-1150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929557PMC
July 2016

Testosterone Attenuates Age-Related Fall in Aerobic Function in Mobility Limited Older Men With Low Testosterone.

J Clin Endocrinol Metab 2016 Jun 6;101(6):2562-9. Epub 2016 Apr 6.

Research Program in Men's Health: Aging and Metabolism (T.W.S., S.Bh., T.G.T., K.P., J.M., S.Ba.), Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women's Hospital, Harvard Medical School, and Harvard T.H. Chan School of Public Health (R.M.), Boston, Massachusetts 02115; and Hebrew SeniorLife Institute for Aging Research (T.G.T.), Roslindale, Massachusetts 02131.

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http://dx.doi.org/10.1210/jc.2015-4333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891791PMC
June 2016

A Subset of Men With Age-Related Decline in Testosterone Have Gonadotroph Autoantibodies.

J Clin Endocrinol Metab 2016 04 10;101(4):1535-41. Epub 2016 Mar 10.

Department of Pathology (A.R., G.D.D., M.V.T., L.D.V., P.C.), The Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Pharmacy (A.R., G.D.D.), Gabriele d'Annunzio University, Chieti, Italy; The Research Program in Men's Health: Aging and Metabolism (T.G.T., R.W.M., S.B., S.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Institute for Aging Research (T.G.T.), Hebrew SeniorLife, Harvard Medical School, Boston, Massachusetts; Feinstone Department of Molecular Microbiology and Immunology (P.C.), The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

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http://dx.doi.org/10.1210/jc.2016-1016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880156PMC
April 2016

Circulating Sex Steroids and Vascular Calcification in Community-Dwelling Men: The Framingham Heart Study.

J Clin Endocrinol Metab 2016 05 1;101(5):2160-7. Epub 2016 Mar 1.

Hebrew SeniorLife Institute for Aging Research (T.G.T.), Roslindale, Massachusetts 02131; Research Program on Men's Health, Aging and Metabolism (T.G.T., S.Bh., S.Ba.), Brigham and Women's Hospital, Boston, Massachusetts 02115; Harvard Medical School (T.G.T., C.J.O., S.Bh., U.H., S.Ba.), Boston, Massachusetts 02115; National Heart, Lung and Blood Institute's Framingham Heart Study (C.J.O., J.M.M., R.S.V., R.B.D.), Framingham, Massachusetts 01702; Cardiology Division (C.J.O.), Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114; Department of Biostatistics (J.M.M.), Boston University School of Public Health, Boston, Massachusetts 02118; Department of Radiology (U.H.), Massachusetts General Hospital, Boston, Massachusetts 02114; Section of Preventive Medicine and Epidemiology (R.S.V.), Boston University School of Medicine, Boston, Massachusetts 02118; and Department of Mathematics (R.B.D.), Boston University, Boston, Massachusetts 02215.

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http://dx.doi.org/10.1210/jc.2015-4299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870846PMC
May 2016

A Perspective on the Evolving Landscape in Male Reproductive Medicine.

Authors:
Shalender Bhasin

J Clin Endocrinol Metab 2016 Mar 23;101(3):827-36. Epub 2016 Feb 23.

Professor of Medicine, Harvard Medical School, Director, The Center for Clinical Investigation, Director, Research Program in Men's Health: Aging and Metabolism, Brigham and Women's Hospital, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1210/jc.2015-3843DOI Listing
March 2016

Effects of Testosterone Treatment in Older Men.

N Engl J Med 2016 Feb;374(7):611-24

From the Division of Endocrinology, Diabetes, and Metabolism (P.J.S.), the Department of Biostatistics and Epidemiology (A.J.S.-S., J.T.F., X.H., B.Z., J.R.L., S.S.E.), the Center for Clinical Epidemiology and Biostatistics (D. Cifelli, D.D., L.F.), and the Division of Cardiovascular Disease, Section of Vascular Medicine, Department of Medicine (E.R.M.), Perelman School of Medicine, University of Pennsylvania, Philadelphia; Research Program in Men's Health: Aging and Metabolism, Brigham and Women's Hospital, Harvard Medical School, Boston (S. Bhasin, T.W.S., S. Basaria), and New England Research Institutes, Watertown (R.C.R.) - both in Massachusetts; the Departments of Medicine and Molecular and Cellular Biology, Division of Diabetes, Endocrinology, and Metabolism, Baylor College of Medicine and Baylor St. Luke's Medical Center, Houston (G.R.C.); Geriatric Research, Education, and Clinical Center, Department of Veterans Affairs (VA) Puget Sound Health Care System, and the Division of Gerontology and Geriatric Medicine, Department of Internal Medicine, University of Washington School of Medicine - both in Seattle (A.M.M.); the Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh (J.A.C.); the Division of Geriatric Medicine, Yale School of Medicine, New Haven, CT (T.M.G.); the Department of Internal Medicine and Division of Epidemiology, Department of Family Medicine and Public Health, University of California, San Diego, School of Medicine, La Jolla (E.B.-C.), the Division of Endocrinology, Harbor-UCLA Medical Center (R.S.S., C.W.), and Los Angeles Biomedical Research Institute (R.S.S., C.W.), Torrance, and the Department of Urology, Moores Comprehensive Cancer Center, University of California, San Diego (J.K.P.) - all in California; the Department of Medicine, Division of Epidemiology and Community Health, University of Minnesota (K.E.E., S.J.D.), and Minneapolis VA Health Care System (K.E.E.) - both in Minneapolis; the D

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February 2016

Advancing methods for US transgender health research.

Curr Opin Endocrinol Diabetes Obes 2016 Apr;23(2):198-207

aThe Fenway Institute, Fenway Health bDepartment of Epidemiology, Harvard T.H. Chan School of Public Health cDivision of General Pediatrics, Boston Children's Hospital/Harvard Medical School, Boston, Massachusetts dDepartment of Family and Community Medicine, University of California, San Francisco, California eResearch Program in Men's Health: Aging and Metabolism Brigham and Women's Hospital, Harvard Medical School Boston, Massachusetts fLGBT Health Initiative, New York State Psychiatric Institute/Columbia Psychiatry and the Columbia University School of Nursing, New York City, New York gQuillen College of Medicine, East Tennessee State University, Johnson City, Tennessee hDepartment of Family Medicine and Community Health, University of Minnesota, School of Medicine, Minneapolis, Minnesota iDepartment of Pediatrics, Northwestern University/Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA jCenter of Expertise on Gender Dysphoria, Department of Medical Psychology, VU University Medical Center, Amsterdam, the Netherlands kCallen-Lorde Community Health Center, New York City, New York lSection of Endocrinology, Diabetes, Nutrition, and Weight Management, Boston University School of Medicine, Boston, Massachusetts mDivision of Endocrinology, Metabolism and Lipids, Department of Medicine, Emory University School of Medicine, Atlanta nThe Atlanta VA Medical Center, Decatur, Georgia, USA oDepartment of Endocrinology and Center for Sexology and Gender, Ghent University Hospital, Ghent, Belgium pDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916925PMC
April 2016

Circulating Estrogen Levels and Self-Reported Health and Mobility Limitation in Community-Dwelling Men of the Framingham Heart Study.

J Gerontol A Biol Sci Med Sci 2017 Aug;72(8):1137-1142

Brigham and Women's Hospital, Research Program in Men's Health, Aging and Metabolism, Harvard Medical School, Boston, Massachusetts.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861927PMC
August 2017

Joint dysfunction and functional decline in middle age myostatin null mice.

Bone 2016 Feb 5;83:141-148. Epub 2015 Nov 5.

Research Program in Men's Health, Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, United States.

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http://dx.doi.org/10.1016/j.bone.2015.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461924PMC
February 2016

Ascertainment of Testosterone Prescribing Practices in the VA.

Med Care 2015 Sep;53(9):746-52

*Center for Healthcare Organization and Implementation Research, Bedford VA Medical Center, Bedford †Department of Health Policy and Management, Boston University School of Public Health ‡Research Program in Men's Health, Aging and Metabolism, Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women's Hospital, Harvard Medical School §Department of Medicine, Section of General Internal Medicine, Boston University School of Medicine, Boston, MA.

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September 2015

The Effects of a Single Developmentally Entrained Pulse of Testosterone in Female Neonatal Mice on Reproductive and Metabolic Functions in Adult Life.

Endocrinology 2015 Oct 1;156(10):3737-46. Epub 2015 Jul 1.

Research Program in Men's Health: Aging and Metabolism (H.J., S.B., T.G., C.S., W.G., K.P., R.J.), Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115; and Boston Nutrition and Obesity Research Center (M.S., M.-J.L., S.K.F.), Section of Endocrinology, Diabetes and Nutrition, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588815PMC
October 2015

Serum Testosterone (T) Level Variability in T Gel-Treated Older Hypogonadal Men: Treatment Monitoring Implications.

J Clin Endocrinol Metab 2015 Sep 29;100(9):3280-7. Epub 2015 Jun 29.

Division of Endocrinology (R.S.S., Y.P., C.W., P.Y.L., P.S.), Department of Medicine, and the Clinical and Translational Science Institute (Y.P., C.W.), Harbor-UCLA Medical Center and Los Angeles Biomedical Research Institute, Torrance, California 90509; The Research Program in Men's Health: Aging and Metabolism (S.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115; Yale University (T.M.G.), New Haven, Connecticut 06510; Division of Gerontology and Geriatric Medicine (A.M.M.), Department of Medicine, University of Washington, and Geriatric Research, Education, and Clinical Center, Veterans Affairs Puget Sound Health Care System (A.M.M.), Seattle, Washington 98108; Department of Aging and Geriatric Research (M.P.), University of Florida, Gainesville, Florida 32611; and Division of Endocrinology (P.J.S.), Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-5160.

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http://dx.doi.org/10.1210/JC.2015-1542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570167PMC
September 2015

Functional Voice Testing Detects Early Changes in Vocal Pitch in Women During Testosterone Administration.

J Clin Endocrinol Metab 2015 Jun 15;100(6):2254-60. Epub 2015 Apr 15.

Section of Men's Health: Aging and Metabolism (G.H., K.M.P., Y.M.B., S.Bh., S.Ba.), Brigham and Women's Hospital, Harvard Medical School, Brookline, Massachusetts 02115; and Department of Speech, Language, and Hearing Sciences (J.A.C.), University of Colorado, Boulder, Colorado 80309.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454796PMC
June 2015

The effects of short-term and long-term testosterone supplementation on blood viscosity and erythrocyte deformability in healthy adult mice.

Endocrinology 2015 May 16;156(5):1623-9. Epub 2015 Mar 16.

Research Program in Men's Health: Aging and Metabolism (W.G., M.L., L.P., K.P., C.S., N.L.S., R.J., M.M., S.Ba., S.Bh.), Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115; Alexion Pharmaceuticals (E.B.), Cambridge, Massachusetts 02142; and Institute of Veterinary Physiology (J.V., M.G.), University of Zürich, CH-8057 Zürich, Switzerland.

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http://dx.doi.org/10.1210/en.2014-1784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398764PMC
May 2015

Effects of testosterone replacement in men with opioid-induced androgen deficiency: a randomized controlled trial.

Pain 2015 Feb;156(2):280-8

aThe Research Program in Men's Health: Aging and Metabolism, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA bDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA cDepartment of Medicine, Boston University School of Medicine, Boston, MA, USA dDepartment of Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA eDepartments of Anesthesiology and Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036339PMC
February 2015

Prolonged hypogonadism in males following withdrawal from anabolic-androgenic steroids: an under-recognized problem.

Addiction 2015 May 25;110(5):823-31. Epub 2015 Feb 25.

Biological Psychiatry Laboratory, McLean Hospital, Belmont, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.

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http://doi.wiley.com/10.1111/add.12850
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May 2015

Association of sex hormones with sexual function, vitality, and physical function of symptomatic older men with low testosterone levels at baseline in the testosterone trials.

J Clin Endocrinol Metab 2015 Mar 30;100(3):1146-55. Epub 2014 Dec 30.

Division of Diabetes, Endocrinology and Metabolism (G.R.C.), Baylor College of Medicine and Baylor St. Luke's Medical Center, Houston, Texas 77030; Center for Clinical Epidemiology & Biostatistics (A.J.S., J.T.F., D.C., L.F.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104; New England Research Institutes, Inc. (R.C.R.), Watertown, Massachusetts 02472; Division of Endocrinology (C.W., R.S.S.), Harbor-University of California at Los Angeles Medical Center and Los Angeles Biomedical Research Institute, Torrance, California 90502; Department of Biostatistics and Epidemiology (S.S.E., X.H.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104; Geriatric Research, Education, and Clinical Center, Department of Veterans Affairs Puget Sound Health Care System (A.M.M.), and Division of Gerontology and Geriatric Medicine, Department of Internal Medicine, University of Washington School of Medicine, Seattle, Washington 98108; Research Program in Men's Health, Aging and Metabolism (S.B., S.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115; Division of Endocrinology, Metabolism and Molecular Medicine (M.E.M.), Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611; Department of Medical Social Sciences (D.C.), Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611; Division of Epidemiology, Department of Family and Preventative Medicine (E.B.), University of California San Diego School of Medicine, La Jolla, California 92093; Department of Epidemiology (J.A.C.), University of Pittsburgh, Graduate School of Public Health, Pittsburgh, Pennsylvania 15261; Divisions of Endocrinology and Geriatrics (J.P.C., V.T.), Albert Einstein College of Medicine, Bronx, New York 10461; Department of Medicine (K.E.E., S.D.), Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota 55415; Minneapolis

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March 2015

The effects of an ActRIIb receptor Fc fusion protein ligand trap in juvenile simian immunodeficiency virus-infected rhesus macaques.

FASEB J 2015 Apr 2;29(4):1165-75. Epub 2014 Dec 2.

*Department of Comparative Pathology, New England Primate Research Center, Southborough, Massachusetts, USA; and Research Program in Men's Health: Aging and Metabolism, Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA

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April 2015

A multi-step, dynamic allosteric model of testosterone's binding to sex hormone binding globulin.

Mol Cell Endocrinol 2015 Jan 21;399:190-200. Epub 2014 Sep 21.

Section of Endocrinology, Diabetes, and Nutrition, Boston Medical Center, Boston University School of Medicine, Boston, MA 02118, USA. Electronic address:

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January 2015

Defining, assessing, and certifying procedural competency in endocrinology, diabetes, and metabolism.

J Clin Endocrinol Metab 2014 Aug 13;99(8):2651-3. Epub 2014 May 13.

Division of Endocrinology, Diabetes, and Metabolism (P.W.L.), Johns Hopkins University School of Medicine, Baltimore, Maryland 21287; Division of Diabetes, Endocrinology, and Metabolism (A.B.), Baylor College of Medicine, Houston, Texas 77030; Division of Endocrinology (A.D.), Veterans Affairs New York Harbor Health Care System and New York University Langone Medical Center, New York, New York 10016; and Research Program in Men's Health: Aging and Metabolism (S.B.), Brigham and Women's Hospital, Boston, Massachusetts 02115.

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August 2014

Testosterone dose-response relationships with cardiovascular risk markers in androgen-deficient women: a randomized, placebo-controlled trial.

J Clin Endocrinol Metab 2014 Jul 8;99(7):E1287-93. Epub 2014 Apr 8.

Section of Men's Health: Aging and Metabolism (G.H., M.D., H.S., T.G.T., S.Bh., S.Ba.), Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115; and Department of Radiology (E.T., A.A., S.A., H.J.), Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts 02118.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079305PMC
July 2014

Research resource: EPSLiM: ensemble predictor for short linear motifs in nuclear hormone receptors.

Mol Endocrinol 2014 May 28;28(5):768-77. Epub 2014 Mar 28.

Research Program in Men's Health: Aging and Metabolism (R.X., S.B., J.C.C., R.J.), Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215; The National Library of Medicine (M.N.Z.), National Center for Bioinformation Technology, The National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892; and Department of Bioengineering (Y.X.), Faculty of Engineering, McGill University, Montreal, Quebec H3A 0C3, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004780PMC
May 2014

Adverse health consequences of performance-enhancing drugs: an Endocrine Society scientific statement.

Endocr Rev 2014 Jun 17;35(3):341-75. Epub 2013 Dec 17.

McLean Hospital (H.G.P.), Harvard Medical School, Belmont, Massachusetts 02478; University of Southern California (R.I.W.), Los Angeles, California 90089; University of Virginia (A.R.), Charlottesville, Virginia 22904; Department of Pharmaceutical Biosciences, (F.N.), Upsala University, SE-751 24, Upsala, Sweden; United States Anti-Doping Agency (L.B.), Colorado Springs, Colorado 80919; and Brigham and Women's Hospital (S.B.), Harvard Medical School, Boston, Massachusetts 02115.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026349PMC
June 2014