Shailaja Kasibhatla

Shailaja Kasibhatla

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Shailaja Kasibhatla

Shailaja Kasibhatla

Publications by authors named "Shailaja Kasibhatla"

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58Publications

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Discovery of Pyridinyl Acetamide Derivatives as Potent, Selective, and Orally Bioavailable Porcupine Inhibitors.

ACS Med Chem Lett 2016 Jul 10;7(7):676-80. Epub 2016 May 10.

Genomics Institute of the Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.

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http://dx.doi.org/10.1021/acsmedchemlett.6b00038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948009PMC
July 2016

Selective activation of apoptosis by a novel set of 4-aryl-3-(3-aryl-1-oxo-2-propenyl)-2(1H)-quinolinones through a Myc-dependent pathway.

Cancer Lett 2009 Feb 12;274(2):243-9. Epub 2008 Nov 12.

EpiCept Corporation, Department of Biology, 6650 Nancy Ridge Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.canlet.2008.09.032DOI Listing
February 2009

Synthesis of caged 2,3,3a,7a-tetrahydro-3,6-methanobenzofuran-7(6H)-ones: Evaluating the minimum structure for apoptosis induction by gambogic acid.

Bioorg Med Chem 2008 Apr 29;16(8):4233-41. Epub 2008 Feb 29.

Epicept Corporation, 6650 Nancy Ridge Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.bmc.2008.02.084DOI Listing
April 2008

Discovery and SAR of indole-2-carboxylic acid benzylidene-hydrazides as a new series of potent apoptosis inducers using a cell-based HTS assay.

Bioorg Med Chem 2004 Jul;12(13):3649-55

Maxim Pharmaceuticals, Inc., 6650 Nancy Ridge Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.bmc.2004.04.017DOI Listing
July 2004

Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay.

Bioorg Med Chem 2004 Jan;12(2):309-17

Maxim Pharmaceuticals, Inc., 6650 Nancy Ridge Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.bmc.2003.11.013DOI Listing
January 2004

N-Ac-DEVD-N'-(Polyfluorobenzoyl)-R110: novel cell-permeable fluorogenic caspase substrates for the detection of caspase activity and apoptosis.

Bioconjug Chem 2003 Mar-Apr;14(2):458-63

Maxim Pharmaceuticals, 6650 Nancy Ridge Drive, San Diego, California 92121, USA.

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http://dx.doi.org/10.1021/bc0256188DOI Listing
November 2003

MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity.

Br J Pharmacol 2003 Sep 26;140(2):402-12. Epub 2003 Aug 26.

Cytovia, Inc. (a subsidiary of Maxim Pharmaceuticals, Inc.), 6650 Nancy Ridge Drive, San Diego, CA 92121, U.S.A.

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http://dx.doi.org/10.1038/sj.bjp.0705450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574042PMC
September 2003

Why target apoptosis in cancer treatment?

Mol Cancer Ther 2003 Jun;2(6):573-80

Maxim Pharmaceuticals, San Diego, California 92121, USA.

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June 2003