Publications by authors named "Seung-Hyo Lee"

42Publications

Genome-wide RNA interference screening reveals a COPI-MAP2K3 pathway required for YAP regulation.

Proc Natl Acad Sci U S A 2020 08 3;117(33):19994-20003. Epub 2020 Aug 3.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, 34141 Daejeon, Korea;

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August 2020

Endothelial Sox17 promotes allergic airway inflammation.

J Allergy Clin Immunol 2019 08 28;144(2):561-573.e6. Epub 2019 Mar 28.

Division of Allergy and Clinical Immunology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. Electronic address:

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August 2019

Neutrophils disturb pulmonary microcirculation in sepsis-induced acute lung injury.

Eur Respir J 2019 03 28;53(3). Epub 2019 Mar 28.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.

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March 2019

TGF-β/SMAD4 mediated UCP2 downregulation contributes to Aspergillus protease-induced inflammation in primary bronchial epithelial cells.

Redox Biol 2018 09 5;18:104-113. Epub 2018 Jul 5.

Graduate School of Medical Science and Engineering, Biomedical Research Center, KAIST Institute for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea. Electronic address:

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September 2018

Effects of 18-Glycyrrhetinic Acid on Fungal Protease-Induced Airway Inflammatory Responses.

Mediators Inflamm 2018 15;2018:6461032. Epub 2018 May 15.

Graduate School of Medical Science and Engineering, Biomedical Research Center, KAIST Institute for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea.

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October 2018

Prediction of drug-induced immune-mediated hepatotoxicity using hepatocyte-like cells derived from human embryonic stem cells.

Toxicology 2017 07 20;387:1-9. Epub 2017 Jun 20.

Biomedical Science and Engineering Interdisciplinary Program, Daejeon, 34141, South Korea; Graduate School of Medical Science and Engineering, Biomedical Research Center, Daejeon, 34141, South Korea. Electronic address:

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July 2017

Bilirubin nanoparticles ameliorate allergic lung inflammation in a mouse model of asthma.

Biomaterials 2017 Sep 12;140:37-44. Epub 2017 Jun 12.

Biomedical Science and Engineering Interdisciplinary Program, KAIST Institute for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 34141, South Korea; Graduate School of Medical Science and Engineering, Biomedical Research Center, KAIST Institute for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 34141, South Korea. Electronic address:

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September 2017

Inositol polyphosphate multikinase promotes Toll-like receptor-induced inflammation by stabilizing TRAF6.

Sci Adv 2017 Apr 21;3(4):e1602296. Epub 2017 Apr 21.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.

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April 2017

Basophil-derived IL-6 regulates T17 cell differentiation and CD4 T cell immunity.

Sci Rep 2017 01 30;7:41744. Epub 2017 Jan 30.

Biomedical Science and Engineering Interdisciplinary Program, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Korea.

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January 2017

Mitochondrial reactive oxygen species regulate fungal protease-induced inflammatory responses.

Toxicology 2017 03 10;378:86-94. Epub 2017 Jan 10.

Graduate School of Medical Science and Engineering, Biomedical Research Center, KAIST Institute for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea. Electronic address:

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March 2017

GM-CSF and IL-4 produced by NKT cells inversely regulate IL-1β production by macrophages.

Immunol Lett 2017 02 4;182:50-56. Epub 2017 Jan 4.

Department of Pathology, Seoul National University College of Medicine, Seoul, Republic of Korea; Laboratory of Immune Regulation in Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea; Ischemic/Hypoxia Institute, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:

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February 2017

Natural killer cells regulate eosinophilic inflammation in chronic rhinosinusitis.

Sci Rep 2016 06 8;6:27615. Epub 2016 Jun 8.

Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, Korea.

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June 2016

Circulating Anti-Elastin Antibody Levels and Arterial Disease Characteristics: Associations with Arterial Stiffness and Atherosclerosis.

Yonsei Med J 2015 Nov;56(6):1545-51

Division of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

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November 2015

TH2 cells and their cytokines regulate formation and function of lymphatic vessels.

Nat Commun 2015 Feb 4;6:6196. Epub 2015 Feb 4.

Graduate School of Medical Science and Engineering, Biomedical Research Center, KAIST Institute for the BioCentury, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.

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February 2015

Non-transcriptional regulation of NLRP3 inflammasome signaling by IL-4.

Immunol Cell Biol 2015 Jul 20;93(6):591-9. Epub 2015 Jan 20.

Department of Microbiology, Brain Korea 21 PLUS Project for Medical Science, Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, Korea.

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July 2015

Interplay between Inflammatory Responses and Lymphatic Vessels.

Immune Netw 2014 Aug 22;14(4):182-6. Epub 2014 Aug 22.

Graduate School of Medical Science and Engineering, and Biomedical Research Center, and KAIST Institute for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701, Korea.

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August 2014

Leukotriene enhanced allergic lung inflammation through induction of chemokine production.

Clin Exp Med 2015 Aug 13;15(3):233-44. Epub 2014 Jun 13.

Cellular Immunology Laboratory, Graduate School of Medical Science and Engineering, Biomedical Research Center, KAIST Institute for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 305-701, Korea.

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August 2015

Role of citrullinated fibrinogen peptides in the activation of CD4 T cells from patients with rheumatoid arthritis.

Immune Netw 2013 Aug 26;13(4):116-22. Epub 2013 Aug 26.

Graduate School of Medical Science and Engineering, Biomedical Research Center, KAIST Institute for the BioCentury, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.

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August 2013

Designed nanocage displaying ligand-specific Peptide bunches for high affinity and biological activity.

ACS Nano 2013 Sep 13;7(9):7462-71. Epub 2013 Aug 13.

Department of Biochemistry and Cell Biology, Cell and Matrix Research Institute, School of Medicine, Kyungpook National University , Daegu 700-422, Republic of Korea.

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September 2013

Innate type 2 immunity is associated with eosinophilic pleural effusion in primary spontaneous pneumothorax.

Am J Respir Crit Care Med 2013 Sep;188(5):577-85

Graduate School of Medical Science and Engineering, Biomedical Research Center, KAIST Institute for the BioCentury, Daejeon, Korea.

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September 2013

CD11a polymorphisms regulate TH2 cell homing and TH2-related disease.

J Allergy Clin Immunol 2014 Jan 29;133(1):189-97.e1-8. Epub 2013 May 29.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, Tex; Department of Medicine, Baylor College of Medicine, Houston, Tex. Electronic address:

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January 2014

Apocynin regulates cytokine production of CD8(+) T cells.

Clin Exp Med 2014 Aug 23;14(3):261-8. Epub 2013 May 23.

Laboratory of Immunology and Infectious Diseases, Graduate School of Medical Science and Engineering, KAIST, 291 Daehak-ro, Daejeon, 305-701, Korea.

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August 2014

Macelignan attenuated allergic lung inflammation and airway hyper-responsiveness in murine experimental asthma.

Life Sci 2013 Jun 30;92(22):1093-9. Epub 2013 Apr 30.

Graduate School of Medical Science and Engineering, Biomedical Research Center, KAIST Institute for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701, Republic of Korea.

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June 2013

CD53, a suppressor of inflammatory cytokine production, is associated with population asthma risk via the functional promoter polymorphism -1560 C>T.

Biochim Biophys Acta 2013 Apr 10;1830(4):3011-8. Epub 2013 Jan 10.

Department of Microbiology, Chung-Ang University College of Medicine, Seoul, Republic of Korea.

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April 2013

Serum elastin-derived peptides and anti-elastin antibody in patients with systemic sclerosis.

J Korean Med Sci 2012 May 25;27(5):484-8. Epub 2012 Apr 25.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

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May 2012

Altered expression of phosphatase of regenerating liver gene family in non-small cell lung cancer.

Oncol Rep 2012 Feb 6;27(2):535-40. Epub 2011 Oct 6.

Graduate School of Medical Science and Engineering, Biomedical Research Center, KAIST Institute for the BioCentury, Korea Advanced Institute of Science and Technology, and Department of Thoracic and Cardiovascular Surgery, Eulji University Hospital, Daejeon 305-701, Republic of Korea.

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February 2012

Cigarette smoke exacerbates mouse allergic asthma through Smad proteins expressed in mast cells.

Respir Res 2011 Apr 18;12:49. Epub 2011 Apr 18.

Department of Pharmacology and Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon 440-726, Korea.

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April 2011

T lymphocytes negatively regulate lymph node lymphatic vessel formation.

Immunity 2011 Jan 20;34(1):96-107. Epub 2011 Jan 20.

National Research Laboratory of Vascular Biology, Korea Advanced Institute of Science and Technology, Daejeon, 305-701, Korea.

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January 2011

Role of th17 cell and autoimmunity in chronic obstructive pulmonary disease.

Immune Netw 2010 Aug 31;10(4):109-14. Epub 2010 Aug 31.

Graduate School of Medical Science and Engineering, Biomedical Research Center, KAIST Institute for the BioCentury, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.

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August 2010

Homing alone? CD18 in infectious and allergic disease.

Trends Mol Med 2004 Jun;10(6):258-62

Department of Immunology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

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June 2004

Airway glycoprotein secretion parallels production and predicts airway obstruction in pulmonary allergy.

J Allergy Clin Immunol 2004 Jan;113(1):72-8

Departments of Immunology and Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.

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January 2004

Differential requirement for CD18 in T-helper effector homing.

Nat Med 2003 Oct 14;9(10):1281-6. Epub 2003 Sep 14.

Biology of Inflammation Center and Department of Immunology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

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October 2003

A protease-activated pathway underlying Th cell type 2 activation and allergic lung disease.

J Immunol 2002 Nov;169(10):5904-11

Biology of Inflammation Center, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX, 77030, USA.

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November 2002