Seung Kwak

Seung Kwak

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Seung Kwak

Publications by authors named "Seung Kwak"

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The optimal sequence of bronchial brushing and washing for diagnosing peripheral lung cancer using non-guided flexible bronchoscopy.

Sci Rep 2020 Jan 23;10(1):1036. Epub 2020 Jan 23.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Inha University Hospital, Inha University School of Medicine, Incheon, 22332, Republic of Korea.

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http://dx.doi.org/10.1038/s41598-020-58010-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978507PMC
January 2020

Full sequence of mutant huntingtin 3'-untranslated region and modulation of its gene regulatory activity by endogenous microRNA.

J Hum Genet 2019 Oct 11;64(10):995-1004. Epub 2019 Jul 11.

Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1038/s10038-019-0639-8DOI Listing
October 2019

Novel DNA Aptamers that Bind to Mutant Huntingtin and Modify Its Activity.

Mol Ther Nucleic Acids 2018 Jun 16;11:416-428. Epub 2018 Mar 16.

Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Neurology, Harvard Medical School, Boston, MA 02114, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S21622531183003
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http://dx.doi.org/10.1016/j.omtn.2018.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992459PMC
June 2018

Population-specific genetic modification of Huntington's disease in Venezuela.

PLoS Genet 2018 05 11;14(5):e1007274. Epub 2018 May 11.

Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965898PMC
May 2018

Small-cell Lung Cancer Presenting as Fatal Pulmonary Hemorrhage.

Open Med (Wars) 2018 21;13:64-66. Epub 2018 Mar 21.

Department of Internal Medicine, Inha University Hospital, 27, Inhang-Ro, Jung-Gu, Incheon, 22332, Republic of Korea.

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http://dx.doi.org/10.1515/med-2018-0009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874507PMC
March 2018

MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice.

PLoS One 2018 11;13(1):e0190550. Epub 2018 Jan 11.

Center for Neurobehavioral Genetics, Semel Institute for Neuroscience & Human Behavior, University of California Los Angeles (UCLA), Los Angeles, CA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190550PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764268PMC
February 2018

Haplotype-based stratification of Huntington's disease.

Eur J Hum Genet 2017 11 23;25(11):1202-1209. Epub 2017 Aug 23.

Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1038/ejhg.2017.125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643960PMC
November 2017

A modifier of Huntington's disease onset at the MLH1 locus.

Hum Mol Genet 2017 10;26(19):3859-3867

Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1093/hmg/ddx286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455020PMC
October 2017

Prognostic impact of a new score using neutrophil-to-lymphocyte ratios in the serum and malignant pleural effusion in lung cancer patients.

BMC Cancer 2017 Aug 22;17(1):557. Epub 2017 Aug 22.

Division of Pulmonology, Department of Internal Medicine, Inha University Hospital, Inha University School of Medicine, 27, Inhang-ro, Jung-gu, Incheon, 22332, South Korea.

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http://dx.doi.org/10.1186/s12885-017-3550-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567470PMC
August 2017

Three Toxic Heavy Metals in Open-Angle Glaucoma with Low-Teen and High-Teen Intraocular Pressure: A Cross-Sectional Study from South Korea.

PLoS One 2016 21;11(10):e0164983. Epub 2016 Oct 21.

Institute of Vision Research, Department of Ophthalmology, Severance Hospital, Yonsei University, College of Medicine, Seoul, Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0164983PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074541PMC
June 2017

Early and brain region-specific decrease of de novo cholesterol biosynthesis in Huntington's disease: A cross-validation study in Q175 knock-in mice.

Neurobiol Dis 2017 Feb 30;98:66-76. Epub 2016 Nov 30.

Department of BioSciences and Centre for Stem Cell Research, Università degli Studi di Milano, 20122 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2016.11.013DOI Listing
February 2017

Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels.

Aging (Albany NY) 2016 07;8(7):1485-512

Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.18632/aging.101005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993344PMC
July 2016

HdhQ111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid Accumulation.

PLoS One 2015 21;10(8):e0134465. Epub 2015 Aug 21.

Center for Human Genetic Research, Massachusetts General Hospital, Department of Neurology, Harvard Medical School, Boston, Massachusetts, United States of America; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134465PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546654PMC
May 2016

The HTT CAG-Expansion Mutation Determines Age at Death but Not Disease Duration in Huntington Disease.

Am J Hum Genet 2016 Feb;98(2):287-98

Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Neurology, Harvard Medical School, Boston, MA 02115, USA; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Genetic Modifiers of Huntington's Disease Consortium. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2015.12.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746370PMC
February 2016

Migratory eosinophilic alveolitis caused by radiation therapy.

J Thorac Dis 2015 May;7(5):E117-21

1 Division of Pulmonology, Department of Internal Medicine, 2 Department of Radiation Oncology, 3 Department of Pathology, Inha University Hospital, Inha University School of Medicine, Incheon, Korea.

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http://dx.doi.org/10.3978/j.issn.2072-1439.2015.05.05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454874PMC
May 2015

Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease.

Sci Transl Med 2014 Dec;6(268):268ra178

Center for Neurobehavioral Genetics, Semel Institute for Neuroscience & Human Behavior, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA. Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. UCLA Brain Research Institute, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1126/scitranslmed.3010523DOI Listing
December 2014

Pancreaticothoracic fistula presenting with hemoptysis and pneumothorax in a chronic alcoholic patient.

Tuberc Respir Dis (Seoul) 2014 May 29;76(5):240-4. Epub 2014 May 29.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea.

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http://dx.doi.org/10.4046/trd.2014.76.5.240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050073PMC
May 2014

Late-onset distant metastatic upper urinary tract urothelial carcinoma mimicking lung adenocarcinoma.

Tuberc Respir Dis (Seoul) 2013 Jul 31;75(1):32-5. Epub 2013 Jul 31.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Inha University Hospital, Inha University School of Medicine, Incheon, Korea.

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http://dx.doi.org/10.4046/trd.2013.75.1.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741472PMC
July 2013

Mediastinal lymphangioma treated using endobronchial ultrasound-guided transbronchial needle aspiration.

Respiration 2012 26;84(6):518-21. Epub 2012 Sep 26.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Inha University Hospital, Inha University School of Medicine, Incheon, Republic of Korea.

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http://dx.doi.org/10.1159/000342872DOI Listing
May 2013

Organizing pneumonia presenting after ulcerative colitis remission.

J Thorac Dis 2013 Apr;5(2):E71-3

Department of Internal Medicine, The Catholic University of Korea College of Medicine, Korea;

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http://dx.doi.org/10.3978/j.issn.2072-1439.2013.03.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621933PMC
April 2013

Gamma linolenic acid exerts anti-inflammatory and anti-fibrotic effects in diabetic nephropathy.

Yonsei Med J 2012 Nov;53(6):1165-75

Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, Korea.

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http://dx.doi.org/10.3349/ymj.2012.53.6.1165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481382PMC
November 2012

A Multicenter Study of Pertussis Infection in Adults with Coughing in Korea: PCR-Based Study.

Tuberc Respir Dis (Seoul) 2012 Nov 30;73(5):266-72. Epub 2012 Nov 30.

Division of Pulmonary, Allergy and Critical Care Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.

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http://dx.doi.org/10.4046/trd.2012.73.5.266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517945PMC
November 2012

Unification of type-II strings and T duality.

Phys Rev Lett 2011 Oct 20;107(17):171603. Epub 2011 Oct 20.

Center for Theoretical Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1103/PhysRevLett.107.171603DOI Listing
October 2011

Circadian Abnormalities in Motor Activity in a BAC Transgenic Mouse Model of Huntington's Disease.

PLoS Curr 2011 Apr 5;3:RRN1225. Epub 2011 Apr 5.

PsychoGenics, Inc.; Princeton University; Barnard College; CHDI Foundation; Barnard College and Columbia University and PsychoGenics/Columbia Univ.

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http://dx.doi.org/10.1371/currents.RRN1225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072044PMC
April 2011

A pulmonary nodule due to pulmonary infarction diagnosed by video-assisted thoracoscopy.

Yonsei Med J 2009 Aug 19;50(4):591-3. Epub 2009 Aug 19.

Department of Internal Medicine, School of Medicine, Inha University, Incheon, Korea.

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http://dx.doi.org/10.3349/ymj.2009.50.4.591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730627PMC
August 2009

Gene expression patterns in glucose-stimulated podocytes.

Biochem Biophys Res Commun 2008 Jun 3;370(3):514-8. Epub 2008 Apr 3.

Department of Internal Medicine, Yonsei University College of Medicine, 134 Shinchon-Dong Seodaemoon-Gu, Seoul 120-752, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2008.03.121DOI Listing
June 2008

Glomerular glucocorticoid receptor expression is reduced in late responders to steroids in adult-onset minimal change disease.

Nephrol Dial Transplant 2008 Jan 22;23(1):169-75. Epub 2007 Sep 22.

Department of Internal Medicine, College of Medicine, Brain Korea 21, Yonsei University, Seodaemoon-Gu, Seoul, Korea.

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https://academic.oup.com/ndt/article-lookup/doi/10.1093/ndt/
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http://dx.doi.org/10.1093/ndt/gfm575DOI Listing
January 2008

[A case of intestinal obstruction caused by strangulated femoral hernia accompanying soft tissue necrosis].

Korean J Gastroenterol 2007 Nov;50(5):340-3

Department of Surgery, Sun General Hospital, Daejeon, Korea.

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November 2007

Myostatin inhibition slows muscle atrophy in rodent models of amyotrophic lateral sclerosis.

Neurobiol Dis 2006 Sep 11;23(3):697-707. Epub 2006 Jul 11.

Department of Physiology, University of Pennsylvania School of Medicine, D400 Richards Building, 3700 Hamilton Walk, Philadelphia, PA 19104-6085, USA.

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http://dx.doi.org/10.1016/j.nbd.2006.05.009DOI Listing
September 2006

A microfluidic protease activity assay based on the detection of fluorescence polarization.

Anal Chim Acta 2006 Sep 27;577(2):171-7. Epub 2006 Jun 27.

Life Sciences Division, Korea Institute of Science and Technology, P.O. Box 131, Cheongryang, Seoul, Republic of Korea.

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http://dx.doi.org/10.1016/j.aca.2006.06.058DOI Listing
September 2006

Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology.

Nature 2006 Aug 16;442(7104):814-7. Epub 2006 Jul 16.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA.

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http://www.nature.com/doifinder/10.1038/nature04976
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http://dx.doi.org/10.1038/nature04976DOI Listing
August 2006

Disruption of ShcA signaling halts cell proliferation--characterization of ShcC residues that influence signaling pathways using yeast.

Cell Signal 2006 Jun 26;18(6):795-806. Epub 2005 Aug 26.

Neuroscience Discovery Research, Wyeth Research, 865 Ridge Road, Monmouth Junction, New Jersey 08852-2718, USA.

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http://dx.doi.org/10.1016/j.cellsig.2005.07.004DOI Listing
June 2006

WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelination.

J Neurosci 2006 May;26(21):5849-59

Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.4921-05.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675261PMC
May 2006

Accessory Kvbeta1 subunits differentially modulate the functional expression of voltage-gated K+ channels in mouse ventricular myocytes.

Circ Res 2005 Mar 20;96(4):451-8. Epub 2005 Jan 20.

Department of Molecular Biology and Pharmacology, Washington University Medical School, St Louis, MO 63110-1093, USA.

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http://dx.doi.org/10.1161/01.RES.0000156890.25876.63DOI Listing
March 2005

Functional expression of human and mouse P2Y12 receptors in Saccharomyces cerevisiae.

Biochem Biophys Res Commun 2004 Nov;324(1):171-7

Discovery Neuroscience, Wyeth Research, Princeton, NJ 08543-8000, USA.

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http://dx.doi.org/10.1016/j.bbrc.2004.09.034DOI Listing
November 2004

The effects of urokinase instillation therapy via percutaneous transthoracic catheter in loculated tuberculous pleural effusion: a randomized prospective study.

Yonsei Med J 2004 Oct;45(5):822-8

Department of Internal Medicine, Pulmonary Division, Inha University Hospital, 7-206, 3-ga, Shinheung-dong, Jung-gu, Incheon 400-103, Korea.

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http://dx.doi.org/10.3349/ymj.2004.45.5.822DOI Listing
October 2004

[A case of chronic acalculous cholecystitis diagnosed by delayed contrast emptying in gallbladder].

Korean J Gastroenterol 2004 May;43(5):320-3

Department of Internal Medicine, Sun General Hospital, Daejeon, Korea.

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May 2004

Characterization of the WAVE1 knock-out mouse: implications for CNS development.

J Neurosci 2003 Apr;23(8):3343-52

Department of Molecular Genetics, Wyeth Research, Princeton, New Jersey 08543, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742295PMC
April 2003

Characterization of mGluR5R, a novel, metabotropic glutamate receptor 5-related gene.

Brain Res Mol Brain Res 2002 Dec;109(1-2):18-33

Wyeth Research, Functional Genomics, 35 Cambridge Park Drive, Cambridge, MA 02140, USA.

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http://dx.doi.org/10.1016/s0169-328x(02)00458-8DOI Listing
December 2002

Foreign body-induced actinomycosis mimicking bronchogenic carcinoma.

Korean J Intern Med 2002 Sep;17(3):207-10

Department of Internal Medicine, College of Medicine, Inha University, Inha General Hospital, Songnam, 7336 Tae Pyuong-4 Dong, Sujong-Ku, Songnam, Kyongkido 461-712, Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531673PMC
http://dx.doi.org/10.3904/kjim.2002.17.3.207DOI Listing
September 2002

Massive hemoptysis after generalized tonic clonic seizure requiring mechanical ventilation.

Yonsei Med J 2002 Aug;43(4):543-6

Department of Internal Medicine, Inha University Hospital, 7-206, 3-Ga, Shinheung-dong, Jung-gu, Inchon 400-103, Korea.

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http://dx.doi.org/10.3349/ymj.2002.43.4.543DOI Listing
August 2002

Modified GFAP promoter auto-regulates tet-activator expression for increased transactivation and reduced tTA-associated toxicity.

Brain Res Mol Brain Res 2002 May;101(1-2):71-81

Wyeth Ayerst Research, Department of Molecular Genetics, CN8000, Princeton, NJ 08543-8000, USA.

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http://dx.doi.org/10.1016/s0169-328x(02)00170-5DOI Listing
May 2002