Seth M Steinberg

Seth M Steinberg

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Seth M Steinberg

Seth M Steinberg

Publications by authors named "Seth M Steinberg"

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Enhanced efficacy of mesothelin-targeted immunotoxin LMB-100 and anti-PD-1 antibody in patients with mesothelioma and mouse tumor models.

Sci Transl Med 2020 Jul;12(550)

Thoracic and GI Malignancies Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1126/scitranslmed.aaz7252DOI Listing
July 2020

A Systematic Review of Pediatric Phase I Trials in Oncology: Toxicity and Outcomes in the Era of Targeted Therapies.

Oncologist 2020 Jun 14;25(6):532-540. Epub 2020 Jan 14.

Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1634/theoncologist.2019-0615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288652PMC
June 2020

Selumetinib in Children with Inoperable Plexiform Neurofibromas.

N Engl J Med 2020 04 18;382(15):1430-1442. Epub 2020 Mar 18.

From the Pediatric Oncology Branch (A.M.G., P.L.W., E.D., P.W., S.M., M.C.R., D.C.P., A.C., J.T., O.K., J.G., B.C.W.) and the Clinical Pharmacology Program (C.J.P., W.D.F.), Center for Cancer Research, National Cancer Institute, and the Rehabilitation Medicine Department, Clinical Center (S.M.P), National Institutes of Health, Bethesda, the Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick (A.B., K.H.), the Cancer Therapy Evaluation Program (M.S., L.A.D.) and the Biostatistics and Data Management Section, Center for Cancer Research (S.M.S., D.J.V.), National Cancer Institute, National Institutes of Health, Shady Grove, and Johns Hopkins University School of Medicine, Baltimore (J.O.B.) - all in Maryland; Children's Hospital of Philadelphia, Philadelphia (M.J.F., A.C.S.); Cincinnati Children's Hospital, Cincinnati (B.W.); Children's National Hospital, Washington, DC (A.K., M.B.); and Indiana University School of Medicine, Indianapolis (D.W.C., C.Z.).

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http://dx.doi.org/10.1056/NEJMoa1912735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305659PMC
April 2020

FDG-PET assessment of malignant pleural mesothelioma: Total Lesion volume and Total Lesion Glycolysis; the central role of volume.

J Nucl Med 2020 Apr 13. Epub 2020 Apr 13.

Thoracic and GI Malignancies Branch, Center for Cancer Research, National Cancer Institute, United States.

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http://dx.doi.org/10.2967/jnumed.119.238733DOI Listing
April 2020

Longitudinal evaluation of peripheral nerve sheath tumors in neurofibromatosis type 1: Growth analysis of plexiform neurofibromas and distinct nodular lesions.

Neuro Oncol 2020 Mar 10. Epub 2020 Mar 10.

Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland, USA.

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http://dx.doi.org/10.1093/neuonc/noaa053DOI Listing
March 2020

Phase 2 Study of Seviteronel (INO-464) in Patients With Metastatic Castration-Resistant Prostate Cancer After Enzalutamide Treatment.

Clin Genitourin Cancer 2020 Mar 29. Epub 2020 Mar 29.

Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD; Clinical Pharmacology Program, Office of the Clinical Director, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD. Electronic address:

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http://dx.doi.org/10.1016/j.clgc.2019.11.002DOI Listing
March 2020

Reproducibility of pharmacogenetics findings for paclitaxel in a heterogeneous population of patients with lung cancer.

PLoS One 2019 28;14(2):e0212097. Epub 2019 Feb 28.

Clinical Pharmacology Program, Office of the Clinical Director, National Cancer Institute, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212097PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394902PMC
November 2019

Qualities and Characteristics of Applicants Associated with Successful Matriculation to Pediatric Surgery Fellowship Training.

J Pediatr Surg 2019 Nov 9. Epub 2019 Nov 9.

Surgical Oncology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jpedsurg.2019.10.057DOI Listing
November 2019

Survey of Surgical Oncology Fellowship Graduates 2005-2016: Insight into Initial Practice.

Ann Surg Oncol 2019 Jun 13;26(6):1622-1628. Epub 2019 Feb 13.

Surgical Oncology Program, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA.

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http://dx.doi.org/10.1245/s10434-019-07220-2DOI Listing
June 2019

Tumor grade and sex should influence the utilization of portal lymphadenectomy for early stage intrahepatic cholangiocarcinoma.

HPB (Oxford) 2019 04 20;21(4):419-424. Epub 2018 Aug 20.

Thoracic and Oncologic Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 10, Room 4-3942, Bethesda, MD, 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.hpb.2018.07.026DOI Listing
April 2019

An Examination of Applicants and Factors Associated with Matriculation to Complex General Surgical Oncology Fellowship Training Programs.

Ann Surg Oncol 2018 Nov 27;25(12):3436-3442. Epub 2018 Jul 27.

Thoracic and Oncologic Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1245/s10434-018-6674-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191290PMC
November 2018

Quick efficacy seeking trial (QuEST1): a novel combination immunotherapy study designed for rapid clinical signal assessment metastatic castration-resistant prostate cancer.

J Immunother Cancer 2018 09 18;6(1):91. Epub 2018 Sep 18.

Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Dr., Room B2L312, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1186/s40425-018-0409-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145343PMC
September 2018

Phase I Study of ATR Inhibitor M6620 in Combination With Topotecan in Patients With Advanced Solid Tumors.

J Clin Oncol 2018 06 18;36(16):1594-1602. Epub 2017 Dec 18.

Anish Thomas, Christophe E. Redon, Linda Sciuto, Emerson Padiernos, Min-Jung Lee, Akira Yuno, Sunmin Lee, Arun Rajan, Udayan Guha, Haobin Chen, Raffit Hassan, Christine C. Alewine, Eva Szabo, Seth M. Steinberg, James H. Doroshow, Mirit I. Aladjem, Jane B. Trepel, and Yves Pommier, National Cancer Institute, Bethesda; Jiuping Ji, Yiping Zhang, Lan Tran, William Yutzy, and Robert J. Kinders, Frederick National Laboratory for Cancer Research, Frederick, MD; and Susan E. Bates, Columbia University Medical Center, New York, NY.

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http://dx.doi.org/10.1200/JCO.2017.76.6915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978471PMC
June 2018

Metabolomic and BH3 profiling of esophageal cancers: novel assessment methods for precision therapy.

BMC Gastroenterol 2018 Jun 22;18(1):94. Epub 2018 Jun 22.

Thoracic and GI Oncology Branch, Center for Cancer Research, National Cancer Institute, Building 10; 4-3952, 10 Center Drive, MSC 1201, Bethesda, MD, 20892-1201, USA.

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http://dx.doi.org/10.1186/s12876-018-0823-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013848PMC
June 2018

Volumetric MRI Analysis of Plexiform Neurofibromas in Neurofibromatosis Type 1: Comparison of Two Methods.

Acad Radiol 2018 02 31;25(2):144-152. Epub 2017 Oct 31.

Center for Cancer Research, Pediatric Oncology Branch, National Cancer Institute, 10 Center Drive, CRC Room 1-5750, Bethesda, MD 20892. Electronic address:

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http://dx.doi.org/10.1016/j.acra.2017.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794522PMC
February 2018

Predictors for Permanent Discontinuation of Systemic Immunosuppression in Severely Affected Chronic Graft-Versus-Host Disease Patients.

Biol Blood Marrow Transplant 2017 Nov 7;23(11):1980-1988. Epub 2017 Aug 7.

Experimental Transplantation and Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2017.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786784PMC
November 2017

Safety in treatment of hepatocellular carcinoma with immune checkpoint inhibitors as compared to melanoma and non-small cell lung cancer.

J Immunother Cancer 2017 11 21;5(1):93. Epub 2017 Nov 21.

Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1186/s40425-017-0298-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697069PMC
November 2017

Thymic epithelial tumors and metastasis to the brain: a case series and systematic review.

Transl Lung Cancer Res 2017 Oct;6(5):588-599

Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.21037/tlcr.2017.08.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653528PMC
October 2017

Clinical significance of IgE in a large cohort of patients with moderate or severe chronic graft-versus-host disease.

Am J Hematol 2017 Aug 1;92(8):E162-E164. Epub 2017 Jun 1.

Experimental Transplantation and Immunology Branch, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland.

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http://dx.doi.org/10.1002/ajh.24768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551423PMC
August 2017

Procalcitonin and cytokine profiles in engraftment syndrome in pediatric stem cell transplantation.

Pediatr Blood Cancer 2017 03 20;64(3). Epub 2016 Oct 20.

Pediatric Oncology Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland.

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http://dx.doi.org/10.1002/pbc.26273DOI Listing
March 2017

Radiology Reports With Hyperlinks Improve Target Lesion Selection and Measurement Concordance in Cancer Trials.

AJR Am J Roentgenol 2017 Feb;208(2):W31-W37

1 Radiology and Imaging Sciences, National Institutes of Health Clinical Center, 9000 Rockville Pike, Bldg 10, Bethesda, MD 20892.

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http://dx.doi.org/10.2214/AJR.16.16845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6762032PMC
February 2017

Pomalidomide for Symptomatic Kaposi's Sarcoma in People With and Without HIV Infection: A Phase I/II Study.

J Clin Oncol 2016 12 31;34(34):4125-4131. Epub 2016 Oct 31.

Mark N. Polizzotto, Thomas S. Uldrick, Kathleen M. Wyvill, Karen Aleman, Cody J. Peer, Frank Maldarelli, Priscila H. Goncalves, William D. Figg, Seth M. Steinberg, and Robert Yarchoan, National Cancer Institute; Margaret Bevans, National Institutes of Health; Irini Sereti, National Institute of Allergy and Infectious Diseases, Bethesda, MD; Denise Whitby and Vickie Marshall, Frederick National Cancer Laboratory for Cancer Research, Frederick, MD; and Vikram Khetani and Jerome B. Zeldis, Celgene Corporation, Summit, NJ.

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http://dx.doi.org/10.1200/JCO.2016.69.3812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477825PMC
December 2016

Identification of novel SNPs associated with risk and prognosis in patients with castration-resistant prostate cancer.

Pharmacogenomics 2016 Dec 24;17(18):1979-1986. Epub 2016 Nov 24.

Clinical Pharmacology Program, Office of the Clinical Director, National Cancer Institute, 9000 Rockville Pike, Building 10, Room 5A01, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.2217/pgs-2016-0134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558514PMC
December 2016

Expression of mesothelin in thymic carcinoma and its potential therapeutic significance.

Lung Cancer 2016 11 28;101:104-110. Epub 2016 Sep 28.

Thoracic and Gastrointestinal Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2016.09.015DOI Listing
November 2016

Mutations in Latinos From the United States and Latin America.

J Glob Oncol 2016 Oct 9;2(5):259-267. Epub 2016 Mar 9.

, Knight Cancer Institute, Oregon Health and Science University, Portland, OR; , , , , , , , and , Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD; , Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru; , Instituto Nacional de Cancerologia, Mexico City, Mexico; , Hospital Oncologico Luis Razetti, Caracas, Venezuela; , Denver Health Medical Center, University of Colorado, Denver, CO; , Kettering Cancer and Blood Specialists, Kettering, OH; and , Facultad de Medicina de la Universidad del Valle, Cochabamba, Bolivia.

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http://dx.doi.org/10.1200/JGO.2015.002105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493261PMC
October 2016

Thoracic Surgery in Chronic Granulomatous Disease: a 25-Year Single-Institution Experience.

J Clin Immunol 2016 10 6;36(7):677-83. Epub 2016 Aug 6.

Thoracic and Gastrointestinal Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1007/s10875-016-0319-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329290PMC
October 2016

Significance of preoperative radiographic pancreatic density in predicting pancreatic fistula after surgery for pancreatic neuroendocrine tumors.

Am J Surg 2016 Jul 12;212(1):40-6. Epub 2015 Dec 12.

Surgery Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD; Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD. Electronic address:

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http://dx.doi.org/10.1016/j.amjsurg.2015.07.031DOI Listing
July 2016

Adjuvant Immunotherapy to Improve Outcome in High-Risk Pediatric Sarcomas.

Clin Cancer Res 2016 07 28;22(13):3182-91. Epub 2016 Jan 28.

Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH Clinical Center, Bethesda, Maryland.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2550DOI Listing
July 2016

Female fertility following dose-adjusted EPOCH-R chemotherapy in primary mediastinal B-cell lymphomas.

Leuk Lymphoma 2016 07 17;57(7):1616-24. Epub 2016 May 17.

a Lymphoid Malignancy Branch, Center for Cancer Research , National Cancer Institute , Bethesda , MD , USA ;

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http://www.tandfonline.com/doi/full/10.3109/10428194.2015.11
Publisher Site
http://dx.doi.org/10.3109/10428194.2015.1118476DOI Listing
July 2016

Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma.

J Clin Oncol 2016 07 23;34(20):2389-97. Epub 2016 May 23.

Stephanie L. Goff, Deborah E. Citrin, Robert P. Somerville, John R. Wunderlich, David N. Danforth, James C. Yang, Richard M. Sherry, Udai S. Kammula, Christopher A. Klebanoff, Marybeth S. Hughes, Nicholas P. Restifo, Michelle M. Langhan, Thomas E. Shelton, Lily Lu, Mei Li M. Kwong, Sadia Ilyas, Nicholas D. Klemen, Eden C. Payabyab, Kathleen E. Morton, Mary Ann Toomey, Seth M. Steinberg, Donald E. White, and Steven A. Rosenberg, National Cancer Institute, National Institutes of Health; Daniel A. Zlott, Clinical Center, National Institutes of Health, Bethesda, MD; and Mark E. Dudley, Novartis Institutes for BioMedical Research, Cambridge, MA.

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http://dx.doi.org/10.1200/JCO.2016.66.7220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981979PMC
July 2016

Resection of primary tumor site is associated with prolonged survival in metastatic nonfunctioning pancreatic neuroendocrine tumors.

Surgery 2016 Jan 6;159(1):311-8. Epub 2015 Oct 6.

Endocrine Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD. Electronic address:

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http://dx.doi.org/10.1016/j.surg.2015.05.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688058PMC
January 2016

Phase II trial of dose-adjusted EPOCH in untreated systemic anaplastic large cell lymphoma.

Haematologica 2016 Jan 30;101(1):e27-9. Epub 2015 Oct 30.

Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.3324/haematol.2015.131151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697904PMC
January 2016

The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl.

Breast Cancer Res Treat 2016 Jan 12;155(2):235-51. Epub 2016 Jan 12.

Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 10, Room 4B54, Bethesda, MD, USA.

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http://dx.doi.org/10.1007/s10549-015-3673-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753803PMC
January 2016

Impact of telomere length on survival in classic and variant hairy cell leukemia.

Leuk Res 2015 Dec 24;39(12):1360-6. Epub 2015 Sep 24.

Laboratory of Molecular Biology, National Cancer Institute (NCI), NIH, United States. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2015.09.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661072PMC
December 2015