Seth M Rubin

Seth M Rubin

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Seth M Rubin

Seth M Rubin

Publications by authors named "Seth M Rubin"

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The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb.

Oncogene 2019 02 11;38(7):1080-1092. Epub 2018 Sep 11.

Division of Hematology, Oncology and Palliative Care and Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, 23298, USA.

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http://www.nature.com/articles/s41388-018-0490-y
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http://dx.doi.org/10.1038/s41388-018-0490-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377300PMC
February 2019

Structural mechanism of Myb-MuvB assembly.

Proc Natl Acad Sci U S A 2018 10 17;115(40):10016-10021. Epub 2018 Sep 17.

Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA 95064;

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http://dx.doi.org/10.1073/pnas.1808136115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176624PMC
October 2018

Heavy metal in cancer: The cell cycle jams with arsenic.

Cell Cycle 2017 09 18;16(18):1641-1642. Epub 2017 Aug 18.

a Department of Chemistry and Biochemistry , University of California , Santa Cruz , CA , USA.

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http://dx.doi.org/10.1080/15384101.2017.1360653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602287PMC
September 2017

Structural basis of divergent cyclin-dependent kinase activation by Spy1/RINGO proteins.

EMBO J 2017 08 30;36(15):2251-2262. Epub 2017 Jun 30.

Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA, USA

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http://dx.doi.org/10.15252/embj.201796905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706343PMC
August 2017

Conservation and divergence of C-terminal domain structure in the retinoblastoma protein family.

Proc Natl Acad Sci U S A 2017 05 24;114(19):4942-4947. Epub 2017 Apr 24.

Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA 95064;

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http://dx.doi.org/10.1073/pnas.1619170114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441720PMC
May 2017

An RB-EZH2 Complex Mediates Silencing of Repetitive DNA Sequences.

Mol Cell 2016 12 23;64(6):1074-1087. Epub 2016 Nov 23.

London Regional Cancer Program, London, ON N6A 4L6, Canada; Children's Health Research Institute, London, ON N6A 4L6, Canada; Department of Biochemistry, Western University, London, ON N6A 3K7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.10.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340194PMC
December 2016

Structural Conservation and E2F Binding Specificity within the Retinoblastoma Pocket Protein Family.

J Mol Biol 2016 10 25;428(20):3960-3971. Epub 2016 Aug 25.

Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA 95064, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00222836163033
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048593PMC
http://dx.doi.org/10.1016/j.jmb.2016.08.017DOI Listing
October 2016

Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters.

Nat Commun 2016 07 28;7:12301. Epub 2016 Jul 28.

Department of Chemistry and Biochemistry, University of California, 1156 High Street, Santa Cruz, California 95064, USA.

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http://dx.doi.org/10.1038/ncomms12301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974476PMC
July 2016

A Strategy for Direct Chemical Activation of the Retinoblastoma Protein.

ACS Chem Biol 2016 05 11;11(5):1192-7. Epub 2016 Feb 11.

Department of Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States.

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http://dx.doi.org/10.1021/acschembio.6b00011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117131PMC
May 2016

Structural basis of template-boundary definition in Tetrahymena telomerase.

Nat Struct Mol Biol 2015 Nov 5;22(11):883-8. Epub 2015 Oct 5.

Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California, USA.

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http://dx.doi.org/10.1038/nsmb.3101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654688PMC
November 2015

Structural mechanisms of DREAM complex assembly and regulation.

Genes Dev 2015 May 27;29(9):961-74. Epub 2015 Apr 27.

Department of Chemistry and Biochemistry, University of California at Santa Cruz, Santa Cruz, California 95064, USA;

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http://genesdev.cshlp.org/lookup/doi/10.1101/gad.257568.114
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http://dx.doi.org/10.1101/gad.257568.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421984PMC
May 2015

Multiple mechanisms for E2F binding inhibition by phosphorylation of the retinoblastoma protein C-terminal domain.

J Mol Biol 2014 Jan 5;426(1):245-55. Epub 2013 Oct 5.

Department of Chemistry and Biochemistry, University of California Santa Cruz, CA 95064, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2013.09.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872205PMC
January 2014

Multisite phosphorylation networks as signal processors for Cdk1.

Nat Struct Mol Biol 2013 Dec 3;20(12):1415-24. Epub 2013 Nov 3.

Institute of Technology, University of Tartu, Tartu, Estonia.

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http://dx.doi.org/10.1038/nsmb.2706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855452PMC
December 2013

Cks confers specificity to phosphorylation-dependent CDK signaling pathways.

Nat Struct Mol Biol 2013 Dec 3;20(12):1407-14. Epub 2013 Nov 3.

1] Department of Chemistry and Biochemistry, University of California, Santa Cruz, Santa Cruz, California, USA. [2].

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http://dx.doi.org/10.1038/nsmb.2707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242096PMC
December 2013

Defining a new vision for the retinoblastoma gene: report from the 3rd International Rb Meeting.

Cell Div 2013 Nov 21;8(1):13. Epub 2013 Nov 21.

Departments of Pediatrics and Genetics, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1186/1747-1028-8-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866465PMC
November 2013

Rif1 and Rif2 shape telomere function and architecture through multivalent Rap1 interactions.

Cell 2013 Jun;153(6):1340-53

Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland.

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http://dx.doi.org/10.1016/j.cell.2013.05.007DOI Listing
June 2013

Molecular mechanisms underlying RB protein function.

Nat Rev Mol Cell Biol 2013 May 18;14(5):297-306. Epub 2013 Apr 18.

London Regional Cancer Program, Children's Health Research Institute, and Department of Biochemistry, Western University, London, Ontario N6A 4L6, Canada.

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http://dx.doi.org/10.1038/nrm3567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754300PMC
May 2013

A Cdk7-Cdk4 T-loop phosphorylation cascade promotes G1 progression.

Mol Cell 2013 Apr;50(2):250-60

Department of Structural and Chemical Biology, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029-6574, USA.

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http://dx.doi.org/10.1016/j.molcel.2013.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677717PMC
April 2013

Deciphering the retinoblastoma protein phosphorylation code.

Authors:
Seth M Rubin

Trends Biochem Sci 2013 Jan 3;38(1):12-9. Epub 2012 Dec 3.

Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA 95064, USA.

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http://dx.doi.org/10.1016/j.tibs.2012.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529988PMC
January 2013

Structures of inactive retinoblastoma protein reveal multiple mechanisms for cell cycle control.

Genes Dev 2012 Jun 8;26(11):1156-66. Epub 2012 May 8.

Department of Chemistry and Biochemistry, University of California at Santa Cruz, Santa Cruz, California 95064, USA.

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http://dx.doi.org/10.1101/gad.189837.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371405PMC
June 2012

Cascades of multisite phosphorylation control Sic1 destruction at the onset of S phase.

Nature 2011 Oct 12;480(7375):128-31. Epub 2011 Oct 12.

Institute of Technology, University of Tartu, Tartu 50411, Estonia.

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http://dx.doi.org/10.1038/nature10560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228899PMC
October 2011

The structure of a monomeric mutant Cks protein reveals multiple functions for a conserved hinge-region proline.

J Mol Biol 2011 Aug 17;411(3):520-8. Epub 2011 Jun 17.

Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, CA 95064, USA.

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http://dx.doi.org/10.1016/j.jmb.2011.05.045DOI Listing
August 2011

Crystal structure of the unliganded retinoblastoma protein pocket domain.

Proteins 2011 Jun 12;79(6):2010-4. Epub 2011 Apr 12.

Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, CA 95064, USA.

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http://dx.doi.org/10.1002/prot.23007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092862PMC
June 2011

Methylation of the retinoblastoma tumor suppressor by SMYD2.

J Biol Chem 2010 Nov 24;285(48):37733-40. Epub 2010 Sep 24.

Departments of Pediatrics, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1074/jbc.M110.137612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988378PMC
November 2010

E2F1 regulation by the APC/C.

Authors:
Seth M Rubin

Cell Cycle 2010 Oct 15;9(20):4044-5. Epub 2010 Oct 15.

Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA, USA.

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http://dx.doi.org/10.4161/cc.9.20.13415DOI Listing
October 2010

E2F1 regulation by the APC/C.

Authors:
Seth M Rubin

Cell Cycle 2010 Oct;9(20):4044

Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA, USA.

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October 2010

An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein.

Nat Struct Mol Biol 2010 Sep 8;17(9):1051-7. Epub 2010 Aug 8.

Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, California, USA.

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http://dx.doi.org/10.1038/nsmb.1868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933323PMC
September 2010

Phosphorylation-induced conformational changes in the retinoblastoma protein inhibit E2F transactivation domain binding.

J Biol Chem 2010 May 11;285(21):16286-93. Epub 2010 Mar 11.

Department of Chemistry and Biochemistry, University of California, Santa Cruz, California 95064, USA.

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http://dx.doi.org/10.1074/jbc.M110.108167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871496PMC
May 2010

Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.

Cell 2005 Dec;123(6):1093-106

Structural Biology Program and Howard Hughes Medical Institute, Memorial Sloan-Kettering Cancer Center, NY 10021, USA.

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http://dx.doi.org/10.1016/j.cell.2005.09.044DOI Listing
December 2005

Distinguishing multiple chemotaxis Y protein conformations with laser-polarized 129Xe NMR.

Protein Sci 2005 Apr 1;14(4):848-55. Epub 2005 Mar 1.

Physical Biosciences Divisions, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA.

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http://dx.doi.org/10.1110/ps.041231005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253452PMC
April 2005

Solution structure of a putative ribosome binding protein from Mycoplasma pneumoniae and comparison to a distant homolog.

J Struct Funct Genomics 2003 ;4(4):235-43

Department of Chemistry, University of California, Berkeley, CA 94720, USA.

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http://dx.doi.org/10.1023/b:jsfg.0000016127.57320.82DOI Listing
March 2005

Design of a conformation-sensitive xenon-binding cavity in the ribose-binding protein.

Angew Chem Int Ed Engl 2004 Nov;43(46):6320-2

Department of Chemistry, University of California at Berkeley, Berkeley, CA 94720, USA.

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http://dx.doi.org/10.1002/anie.200460629DOI Listing
November 2004

Development of a functionalized xenon biosensor.

J Am Chem Soc 2004 Nov;126(46):15287-94

Department of Chemistry, University of California at Berkeley, Berkeley, California 94720, USA.

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http://dx.doi.org/10.1021/ja0483037DOI Listing
November 2004

Applications of laser-polarized 129Xe to biomolecular assays.

Magn Reson Imaging 2003 Dec;21(10):1235-9

Department of Chemistry, University of California at Berkeley, Berkeley, CA 94720, USA.

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http://dx.doi.org/10.1016/j.mri.2003.08.025DOI Listing
December 2003

Detection and characterization of xenon-binding sites in proteins by 129Xe NMR spectroscopy.

J Mol Biol 2002 Sep;322(2):425-40

Department of Chemistry, MC-1460, University of California, Berkeley 94720-1460, USA.

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http://dx.doi.org/10.1016/s0022-2836(02)00739-8DOI Listing
September 2002