Publications by authors named "Seth L Masters"

99Publications

Pharmacological validation of targets regulating CD14 during macrophage differentiation.

EBioMedicine 2020 Oct 7;61:103039. Epub 2020 Oct 7.

Immunology Catalyst, Immunology Network, Adaptive Immunity Research Unit, GSK, Stevenage, UK; Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2020.103039DOI Listing
October 2020

TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.

Cell 2020 Oct 7;183(3):636-649.e18. Epub 2020 Oct 7.

Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia; Immunology Laboratory, Guangzhou Institute of Paediatrics, Guangzhou Women and Children's Medical Centre, Guangzhou, Guangdong 510623, China. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.09.020DOI Listing
October 2020

Excessive deubiquitination of NLRP3-R779C variant contributes to very-early-onset inflammatory bowel disease development.

J Allergy Clin Immunol 2020 Sep 15. Epub 2020 Sep 15.

MOE Key Laboratory of Gene Function and Regulation, Department of Gastroenterology and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2020.09.003DOI Listing
September 2020

Constitutive immune mechanisms: mediators of host defence and immune regulation.

Nat Rev Immunol 2020 Aug 11. Epub 2020 Aug 11.

Department of Biomedicine, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1038/s41577-020-0391-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418297PMC
August 2020

A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction.

Nat Commun 2020 06 19;11(1):3150. Epub 2020 Jun 19.

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.

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http://dx.doi.org/10.1038/s41467-020-16819-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305203PMC
June 2020

TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells.

Cell Rep 2020 04;31(1):107492

Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3010, Australia; Department of Anatomy and Developmental Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.03.056DOI Listing
April 2020

Compound Heterozygous Mutations of IL12RB1 in a Patient with Selective Defects in Th17 Differentiation.

J Clin Immunol 2020 May 27;40(4):647-652. Epub 2020 Mar 27.

Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Centre, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510006, China.

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http://dx.doi.org/10.1007/s10875-020-00771-0DOI Listing
May 2020

SIDT1 Localizes to Endolysosomes and Mediates Double-Stranded RNA Transport into the Cytoplasm.

J Immunol 2019 06 6;202(12):3483-3492. Epub 2019 May 6.

Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia;

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1801369
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http://dx.doi.org/10.4049/jimmunol.1801369DOI Listing
June 2019

Lack of protein prenylation promotes NLRP3 inflammasome assembly in human monocytes.

J Allergy Clin Immunol 2019 06 21;143(6):2315-2317.e3. Epub 2019 Feb 21.

Bone Biology, Garvan Institute of Medical Research and St Vincent's Clinical School, UNSW Sydney, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.02.013DOI Listing
June 2019

The Salmonella pathogenicity island-2 subverts human NLRP3 and NLRC4 inflammasome responses.

J Leukoc Biol 2019 02 4;105(2):401-410. Epub 2018 Oct 4.

Institute for Molecular Bioscience (IMB), IMB Centre for Inflammation and Disease Research, The University of Queensland, Brisbane, Queensland, Australia.

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http://doi.wiley.com/10.1002/JLB.MA0318-112RR
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http://dx.doi.org/10.1002/JLB.MA0318-112RRDOI Listing
February 2019

Ximmer: a system for improving accuracy and consistency of CNV calling from exome data.

Gigascience 2018 10 1;7(10). Epub 2018 Oct 1.

Bioinformatics, Murdoch Children's Research Institute, Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052 Australia.

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http://dx.doi.org/10.1093/gigascience/giy112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177737PMC
October 2018

The classification, genetic diagnosis and modelling of monogenic autoinflammatory disorders.

Clin Sci (Lond) 2018 09 5;132(17):1901-1924. Epub 2018 Sep 5.

Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.

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http://dx.doi.org/10.1042/CS20171498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123071PMC
September 2018

Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling.

J Biol Chem 2018 09 3;293(39):15195-15207. Epub 2018 Aug 3.

From the Inflammation Division, Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1074/jbc.RA118.003314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166714PMC
September 2018

Membrane vesicles from Pseudomonas aeruginosa activate the noncanonical inflammasome through caspase-5 in human monocytes.

Immunol Cell Biol 2018 11 14;96(10):1120-1130. Epub 2018 Aug 14.

Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, 3168, Australia.

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http://doi.wiley.com/10.1111/imcb.12190
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http://dx.doi.org/10.1111/imcb.12190DOI Listing
November 2018

An Update on Autoinflammatory Diseases: Relopathies.

Curr Rheumatol Rep 2018 05 30;20(7):39. Epub 2018 May 30.

Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Australia.

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http://link.springer.com/10.1007/s11926-018-0749-x
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http://dx.doi.org/10.1007/s11926-018-0749-xDOI Listing
May 2018

An Update on Autoinflammatory Diseases: Inflammasomopathies.

Curr Rheumatol Rep 2018 05 30;20(7):40. Epub 2018 May 30.

Inflammation division, The Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Australia.

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http://dx.doi.org/10.1007/s11926-018-0750-4DOI Listing
May 2018

An Update on Autoinflammatory Diseases: Interferonopathies.

Curr Rheumatol Rep 2018 05 30;20(7):38. Epub 2018 May 30.

Inflammation division, The Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Australia.

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http://dx.doi.org/10.1007/s11926-018-0748-yDOI Listing
May 2018

Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)-LRR oligomerization interface.

J Allergy Clin Immunol 2018 12 17;142(6):1956-1967.e6. Epub 2018 May 17.

Inflammation Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Australia; Department of Medical Biology, University of Melbourne, Parkville, Australia; Immunology Laboratory, Guangzhou Institute of Paediatrics, Guangzhou, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183071
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http://dx.doi.org/10.1016/j.jaci.2018.04.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281029PMC
December 2018

Caspase substrates won't be defined by a four-letter code.

J Biol Chem 2018 05;293(18):7068-7069

From the Division of Inflammation, The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia and

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http://dx.doi.org/10.1074/jbc.H118.002802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936799PMC
May 2018

The NLRP3 Inflammasome Suppresses Protective Immunity to Gastrointestinal Helminth Infection.

Cell Rep 2018 04;23(4):1085-1098

Australian Institute of Tropical Health and Medicine, James Cook University, Smithfield, QLD 4878, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.03.097DOI Listing
April 2018

Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism.

Cell Metab 2018 May 19;27(5):1096-1110.e5. Epub 2018 Apr 19.

Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC 3004, Australia; Garvan Institute of Medical Research, 384 Victoria St, Sydney, NSW 2010, Australia; Faculty of Medicine, St Vincent's Clinical School, Faculty of Medicine, University of NSW, Sydney, NSW 2010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.03.014DOI Listing
May 2018

Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment.

Cancer Cell 2018 04;33(4):634-648.e5

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, 4006 QLD, Australia; School of Medicine, University of Queensland, St Lucia 4006 QLD, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.02.007DOI Listing
April 2018

Generation of Genetic Knockouts in Myeloid Cell Lines Using a Lentiviral CRISPR/Cas9 System.

Methods Mol Biol 2018 ;1714:41-55

Inflammation division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC, 3052, Australia.

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http://dx.doi.org/10.1007/978-1-4939-7519-8_3DOI Listing
July 2018

SIDT2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition.

Immunity 2017 09 12;47(3):498-509.e6. Epub 2017 Sep 12.

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Murdoch Childrens Research Institute, Parkville, VIC, Australia; Department of Paediatrics, University of Melbourne, Parkville, VIC, Australia; Department of Psychiatry, University of Melbourne, Parkville, VIC, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679266PMC
September 2017

Mechanisms of NLRP1-Mediated Autoinflammatory Disease in Humans and Mice.

J Mol Biol 2018 01 19;430(2):142-152. Epub 2017 Jul 19.

Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia.

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http://dx.doi.org/10.1016/j.jmb.2017.07.012DOI Listing
January 2018

A Homolog of Eukaryotic Flotillin Is Involved in Cholesterol Accumulation, Epithelial Cell Responses and Host Colonization.

Front Cell Infect Microbiol 2017 6;7:219. Epub 2017 Jun 6.

Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical ResearchMelbourne, VIC, Australia.

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http://dx.doi.org/10.3389/fcimb.2017.00219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460342PMC
February 2018

Posttranslational Modification as a Critical Determinant of Cytoplasmic Innate Immune Recognition.

Physiol Rev 2017 07;97(3):1165-1209

Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia; Hudson Institute of Medical Research, Monash University, Centre for Innate Immunity and Infectious Diseases, Clayton, Victoria, Australia; The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; and Departments of Medical Biology and of Microbiology and Immunology, The University of Melbourne, Parkville, Australia.

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http://dx.doi.org/10.1152/physrev.00026.2016DOI Listing
July 2017

The RNA-binding protein Tristetraprolin (TTP) is a critical negative regulator of the NLRP3 inflammasome.

J Biol Chem 2017 04 16;292(17):6869-6881. Epub 2017 Mar 16.

From the School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland,

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http://dx.doi.org/10.1074/jbc.M116.772947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409458PMC
April 2017

Strain 130b Evades Macrophage Cell Death Independent of the Effector SidF in the Absence of Flagellin.

Front Cell Infect Microbiol 2017 16;7:35. Epub 2017 Feb 16.

Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University Clayton, VIC, Australia.

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http://dx.doi.org/10.3389/fcimb.2017.00035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311068PMC
June 2017

Homeostasis-altering molecular processes as mechanisms of inflammasome activation.

Nat Rev Immunol 2017 Mar 6;17(3):208-214. Epub 2017 Feb 6.

Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia; and at the Department of Medical Biology, University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1038/nri.2016.151DOI Listing
March 2017

Inflammasome Priming in Sterile Inflammatory Disease.

Trends Mol Med 2017 02 18;23(2):165-180. Epub 2017 Jan 18.

Immunology Catalyst, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK; Department of Medical Biology, University of Melbourne, Parkville 3010, Australia; Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2016.12.007DOI Listing
February 2017

Inflammasome Priming in Sterile Inflammatory Disease.

Trends Mol Med 2017 02 18;23(2):165-180. Epub 2017 Jan 18.

Immunology Catalyst, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK; Department of Medical Biology, University of Melbourne, Parkville 3010, Australia; Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2016.12.007DOI Listing
February 2017

Intercellular communication for innate immunity.

Mol Immunol 2017 06 18;86:16-22. Epub 2016 Oct 18.

Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia.

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http://dx.doi.org/10.1016/j.molimm.2016.10.002DOI Listing
June 2017

The modern interleukin-1 superfamily: Divergent roles in obesity.

Semin Immunol 2016 10 7;28(5):441-449. Epub 2016 Oct 7.

Haematopoiesis and Leukocyte Biology, Baker IDI Heart & Diabetes Institute, Melbourne, Victoria, 3004, Australia; Department of Immunology, Monash University, Melbourne, Victoria, 3004, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.smim.2016.10.001DOI Listing
October 2016

Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation.

Cell 2016 Sep;167(1):187-202.e17

Institute of Medical Biology, A(∗)STAR, Singapore 138632, Singapore; Institute of Molecular and Cellular Biology, A(∗)STAR, Singapore 138632, Singapore; Medical Genetics Department, Koç University School of Medicine, 34010 Istanbul, Turkey; Department of Paediatrics, National University of Singapore, Singapore 119228, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.09.001DOI Listing
September 2016

Avenues to autoimmune arthritis triggered by diverse remote inflammatory challenges.

J Autoimmun 2016 09 12;73:120-9. Epub 2016 Jul 12.

Infection and Immunity Program, Monash Biomedicine Discovery Institute, Monash University, 3800 VIC, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2016.06.018DOI Listing
September 2016

Regulation of Starch Stores by a Ca(2+)-Dependent Protein Kinase Is Essential for Viable Cyst Development in Toxoplasma gondii.

Cell Host Microbe 2015 Dec;18(6):670-81

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Victoria, 3052, Australia; Department of Medical Biology, The University of Melbourne, Victoria, 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2015.11.004DOI Listing
December 2015

ATF3 Is a Key Regulator of Macrophage IFN Responses.

J Immunol 2015 Nov 28;195(9):4446-55. Epub 2015 Sep 28.

Institute of Innate Immunity, University Hospital, University of Bonn, 53127 Bonn, Germany; Inflammation Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, Victoria 3010, Australia;

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http://dx.doi.org/10.4049/jimmunol.1500204DOI Listing
November 2015

A Toxoplasma gondii Gluconeogenic Enzyme Contributes to Robust Central Carbon Metabolism and Is Essential for Replication and Virulence.

Cell Host Microbe 2015 Aug;18(2):210-20

Department of Biochemistry and Molecular Biology, Bio21 Institute of Molecular Science and Biotechnology, The University of Melbourne, Parkville, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2015.07.008DOI Listing
August 2015

Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.

J Immunol 2015 Aug 26;195(3):1233-41. Epub 2015 Jun 26.

School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane 4072, Queensland, Australia; Institute for Molecular Bioscience, The University of Queensland, Brisbane 4072, Queensland, Australia

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http://dx.doi.org/10.4049/jimmunol.1402859DOI Listing
August 2015

Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β.

J Exp Med 2015 Jun 25;212(6):927-38. Epub 2015 May 25.

Division of Inflammation, Division of Cancer and Hematology, Division of Immunology, and ACRF Chemical Biology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia Department of Medical Biology, The University of Melbourne, Parkville, Victoria 3010, Australia

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http://dx.doi.org/10.1084/jem.20142384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451132PMC
June 2015

Broadening the definition of autoinflammation.

Authors:
Seth L Masters

Semin Immunopathol 2015 Jul 21;37(4):311-2. Epub 2015 May 21.

Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Australia,

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http://dx.doi.org/10.1007/s00281-015-0497-1DOI Listing
July 2015

Monogenic autoinflammatory diseases: Cytokinopathies.

Cytokine 2015 Aug 23;74(2):237-46. Epub 2015 Mar 23.

Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2015.02.012DOI Listing
August 2015

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL.

Nat Commun 2015 Feb 18;6:6282. Epub 2015 Feb 18.

1] Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3052, Australia [2] Department of Medical Biology, the University of Melbourne, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1038/ncomms7282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346630PMC
February 2015

Fas regulates neutrophil lifespan during viral and bacterial infection.

J Leukoc Biol 2015 Feb 3;97(2):321-6. Epub 2014 Dec 3.

*Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia; Department of Medical Biology and Faculty of Medicine, University of Melbourne, Parkville, Victoria, Australia; Department of Microbiology and Immunology, University of Melbourne at Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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http://www.jleukbio.org/content/early/2014/11/26/jlb.3AB1113
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http://www.jleukbio.org/cgi/doi/10.1189/jlb.3AB1113-594RR
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http://dx.doi.org/10.1189/jlb.3AB1113-594RRDOI Listing
February 2015

Activation of the NLRP3 inflammasome complex is not required for stress-induced death of pancreatic islets.

PLoS One 2014 18;9(11):e113128. Epub 2014 Nov 18.

St Vincent's Institute, Fitzroy, Victoria, Australia; The University of Melbourne Department of Medicine, St. Vincent's Hospital, Fitzroy, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0113128PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236141PMC
April 2016

A healthy appetite for Toxoplasma at the cellular level.

Immunol Cell Biol 2014 Nov 2;92(10):813-4. Epub 2014 Sep 2.

Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1038/icb.2014.72DOI Listing
November 2014

Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity.

Cell Metab 2014 May;19(5):821-35

Haematopoiesis and Leukocyte Biology, Baker IDI Heart and Diabetes Institute, Melbourne VIC 3004, Australia; Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY 10032, USA; Department of Immunology, Monash University, Melbourne VIC 3004, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2014.03.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048939PMC
May 2014

NLRP1a expression in Srebp-1a-deficient mice.

Cell Metab 2014 Mar;19(3):345-6

The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15504131140005
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http://dx.doi.org/10.1016/j.cmet.2014.02.002DOI Listing
March 2014

Innate immunity.

Curr Opin Immunol 2014 Feb 1;26:v-vi. Epub 2014 Feb 1.

Institute of Innate Immunity, University Hospital, University of Bonn, 53127 Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2013.12.006DOI Listing
February 2014

Activating the NLRP3 inflammasome using the amyloidogenic peptide IAPP.

Methods Mol Biol 2013 ;1040:9-18

Department of Pathology and Laboratory Medicine, Child and Family Research Institute, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1007/978-1-62703-523-1_2DOI Listing
February 2014

Transcriptional analysis of the three Nlrp1 paralogs in mice.

BMC Genomics 2013 Mar 18;14:188. Epub 2013 Mar 18.

Microbial Pathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 33 North Drive, Bethesda, MD 20892-3202, USA.

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http://dx.doi.org/10.1186/1471-2164-14-188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641005PMC
March 2013

Specific inflammasomes in complex diseases.

Authors:
Seth L Masters

Clin Immunol 2013 Jun 21;147(3):223-8. Epub 2012 Dec 21.

The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.

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http://dx.doi.org/10.1016/j.clim.2012.12.006DOI Listing
June 2013

Linking metabolic abnormalities to apoptotic pathways in Beta cells in type 2 diabetes.

Cells 2013 Apr 26;2(2):266-83. Epub 2013 Apr 26.

Immunology and Diabetes Unit, St Vincent's Institute, Fitzroy, Victoria, 3065 Australia.

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http://dx.doi.org/10.3390/cells2020266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972679PMC
April 2013

Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1β production.

J Immunol 2012 Oct 14;189(8):3795-9. Epub 2012 Sep 14.

Inflammation Research Group and Immunology Research Centre, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 4, Ireland.

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http://dx.doi.org/10.4049/jimmunol.1200312DOI Listing
October 2012

TLR regulation of SPSB1 controls inducible nitric oxide synthase induction.

J Immunol 2011 Oct 29;187(7):3798-805. Epub 2011 Aug 29.

Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1002993
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http://dx.doi.org/10.4049/jimmunol.1002993DOI Listing
October 2011

The inflammasome in atherosclerosis and type 2 diabetes.

Sci Transl Med 2011 May;3(81):81ps17

Immunology Research Centre, Inflammation Research Group, School of Biochemistry and Immunology, Trinity College Dublin, Ireland.

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http://stm.sciencemag.org/cgi/doi/10.1126/scitranslmed.30019
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http://dx.doi.org/10.1126/scitranslmed.3001902DOI Listing
May 2011

Disease-associated amyloid and misfolded protein aggregates activate the inflammasome.

Trends Mol Med 2011 May 2;17(5):276-82. Epub 2011 Mar 2.

Immunology Research Centre, Inflammation Research Group, School of Biochemistry and Immunology, Trinity College Dublin, Ireland.

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http://dx.doi.org/10.1016/j.molmed.2011.01.005DOI Listing
May 2011

Familial Mediterranean fever with a single MEFV mutation: where is the second hit?

Arthritis Rheum 2009 Jun;60(6):1851-61

Genetics and Genomics Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, Maryland 20892-1820, USA.

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http://dx.doi.org/10.1002/art.24569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753538PMC
June 2009

Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*).

Annu Rev Immunol 2009 ;27:621-68

The National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1146/annurev.immunol.25.022106.141627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996236PMC
May 2009

SPRY domain-containing SOCS box protein 2: crystal structure and residues critical for protein binding.

J Mol Biol 2009 Feb 6;386(3):662-74. Epub 2009 Jan 6.

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3052, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S002228360801573
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http://dx.doi.org/10.1016/j.jmb.2008.12.078DOI Listing
February 2009

Recent advances in the molecular pathogenesis of hereditary recurrent fevers.

Curr Opin Allergy Clin Immunol 2006 Dec;6(6):428-33

The National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda 20892, Maryland, USA.

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http://dx.doi.org/10.1097/ACI.0b013e3280109b57DOI Listing
December 2006

Dynamics of the SPRY domain-containing SOCS box protein 2: flexibility of key functional loops.

Protein Sci 2006 Dec 6;15(12):2761-72. Epub 2006 Nov 6.

The Walter and Eliza Hall Institute of Medical Research, Parkville 3050, Victoria, Australia.

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http://dx.doi.org/10.1110/ps.062477806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242441PMC
December 2006

The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production.

Proc Natl Acad Sci U S A 2006 Jun 19;103(26):9982-7. Epub 2006 Jun 19.

Genetics and Genomics Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.0602081103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479864PMC
June 2006

The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues.

Nat Struct Mol Biol 2006 Jan 20;13(1):77-84. Epub 2005 Dec 20.

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3050, Victoria, Australia.

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http://dx.doi.org/10.1038/nsmb1034DOI Listing
January 2006

The molybdate binding protein Mop from Haemophilus influenzae--biochemical and thermodynamic characterisation.

Arch Biochem Biophys 2005 Jul;439(1):105-12

Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, Vic. 3010, Australia.

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http://dx.doi.org/10.1016/j.abb.2005.04.020DOI Listing
July 2005