Publications by authors named "Seth A Wander"

24Publications

Cyclin-dependent kinase 4 and 6 inhibitors for hormone receptor-positive breast cancer: past, present, and future.

Lancet 2020 03;395(10226):817-827

Department of Medical Oncology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA. Electronic address:

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March 2020

Genetics to epigenetics: targeting histone deacetylases in hormone receptor-positive metastatic breast cancer.

Lancet Oncol 2019 06 27;20(6):746-748. Epub 2019 Apr 27.

Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA. Electronic address:

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June 2019

p27 transcriptionally coregulates cJun to drive programs of tumor progression.

Proc Natl Acad Sci U S A 2019 04 15;116(14):7005-7014. Epub 2019 Mar 15.

Braman Family Breast Cancer Institute, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136;

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April 2019

MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance.

Cell Rep 2019 03;26(10):2667-2680.e7

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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March 2019

CDK 4/6 Inhibitors in Breast Cancer: Current Controversies and Future Directions.

Curr Oncol Rep 2019 02 26;21(3):25. Epub 2019 Feb 26.

Massachusetts General Hospital Cancer Center, Harvard Medical School, Lawrence House 304, 10 North Grove St, Boston, MA, 02114, USA.

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February 2019

Blocking the Cycle: Cyclin-Dependent Kinase 4/6 Inhibitors in Metastatic, Hormone Receptor-Positive Breast Cancer.

J Clin Oncol 2017 Sep 3;35(25):2866-2870. Epub 2017 Jun 3.

Seth A. Wander, Erica L. Mayer, and Harold J. Burstein, Dana-Farber Cancer Institute; Brigham & Women's Hospital; Harvard Medical School, Boston, MA.

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September 2017

Elevation of Urinary 2-Hydroxyglutarate in IDH-Mutant Glioma.

Oncologist 2016 Feb 1;21(2):214-9. Epub 2016 Feb 1.

Division of Neuro-Oncology, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA Division of Hematology/Oncology, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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February 2016

Interactions between Adipocytes and Breast Cancer Cells Stimulate Cytokine Production and Drive Src/Sox2/miR-302b-Mediated Malignant Progression.

Cancer Res 2016 Jan 7;76(2):491-504. Epub 2016 Jan 7.

Braman Family Breast Cancer Institute, UM Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida. Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, Florida. Donald and Sheila Fuente Graduate Program in Cancer Biology, University of Miami Miller School of Medicine, Miami, Florida. Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida.

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January 2016

Biochemical, Epigenetic, and Metabolic Approaches to Target IDH Mutations in Acute Myeloid Leukemia.

Semin Hematol 2015 Jul 17;52(3):165-71. Epub 2015 Mar 17.

University of Maryland, School of Medicine, Marlene and Stewart Greenebaum Cancer Center, Baltimore, MD. Electronic address:

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July 2015

The evolving role of FLT3 inhibitors in acute myeloid leukemia: quizartinib and beyond.

Ther Adv Hematol 2014 Jun;5(3):65-77

Massachusetts General Hospital, Harvard Medical School, Zero Emerson Place, Suite 118, Boston, MA 02114, USA.

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June 2014

Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses.

EMBO Mol Med 2013 10 27;5(10):1502-22. Epub 2013 Aug 27.

Braman Family Breast Cancer Institute, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA; Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL, USA.

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October 2013

Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy.

J Clin Invest 2011 Apr 1;121(4):1231-41. Epub 2011 Apr 1.

Braman Family Breast Cancer Institute, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida 33136, USA.

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April 2011

p27: a barometer of signaling deregulation and potential predictor of response to targeted therapies.

Clin Cancer Res 2011 Jan 21;17(1):12-8. Epub 2010 Oct 21.

Braman Family Breast Cancer Institute, University of Miami Sylvester Comprehensive Cancer Center, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida 33136, USA.

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January 2011

Combined Src and ER blockade impairs human breast cancer proliferation in vitro and in vivo.

Breast Cancer Res Treat 2011 Jul 29;128(1):69-78. Epub 2010 Jul 29.

Braman Family Breast Cancer Institute, University of Miami Sylvester Comprehensive Cancer Center, Miami, FL, 33136, USA.

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July 2011

p27 as Jekyll and Hyde: regulation of cell cycle and cell motility.

Cell Cycle 2009 Nov 11;8(21):3455-61. Epub 2009 Nov 11.

Braman Family Breast Cancer Institute, University of Miami Sylvester Comprehensive Cancer Center and Department of Biochemistry and Molecular Biology, UM Miller School of Medicine, Miami, FL, USA.

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November 2009

RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility.

Proc Natl Acad Sci U S A 2009 Jun 22;106(23):9268-73. Epub 2009 May 22.

Department of Biochemistry and Molecular Biology, Braman Family Breast Cancer Institute, University of Miami Sylvester Comprehensive Cancer Center, Miami, FL 33136, USA.

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June 2009