Publications by authors named "Serkan Cetin"

4 Publications

  • Page 1 of 1

The Usefulness of Admission Plasma NT-pro BNP Level to Predict Left Ventricular Aneurysm Formation after Acute ST-Segment Elevation Myocardial Infarction.

Arq Bras Cardiol 2019 12;113(6):1129-1137

University of Health Science, Turkiye Yuksek Ihtisas Training and Research Hospital - Cardiology, Ankara - Turkey.

Background: Left ventricular aneurysm (LVA) is an important complication of acute myocardial infarction. In this study, we investigated the role of N- Terminal pro B type natriuretic peptide level to predict the LVA development after acute ST-segment elevation myocardial infarction (STEMI).

Methods: We prospectively enrolled 1519 consecutive patients with STEMI. Patients were divided into two groups according to LVA development within the six months after index myocardial infarction. Patients with or without LVAs were examined to determine if a significant relationship existed between the baseline N- Terminal pro B type natriuretic peptide values and clinical characteristics. A p-value < 0.05 was considered statistically significant.

Results: LVA was detected in 157 patients (10.3%). The baseline N- Terminal pro- B type natriuretic peptide level was significantly higher in patients who developed LVA after acute MI (523.5 ± 231.1 pg/mL vs. 192.3 ± 176.6 pg/mL, respectively, p < 0.001). Independent predictors of LVA formation after acute myocardial infarction was age > 65 y, smoking, Killip class > 2, previous coronary artery bypass graft, post-myocardial infarction heart failure, left ventricular ejection fraction < 50%, failure of reperfusion, no-reflow phenomenon, peak troponin I and CK-MB and NT-pro BNP > 400 pg/mL at admission.

Conclusions: Our findings indicate that plasma N- Terminal pro B type natriuretic peptide level at admission among other variables provides valuable predictive information regarding the development of LVA after acute STEMI.
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December 2019

Invasive screening for lower extremity peripheral artery disease: Killing two birds with one stone?

Vascular 2020 04 11;28(2):196-202. Epub 2019 Oct 11.

Department of Cardiology, TOBB Economics and Technology University Medical School, Ankara, Turkey.

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April 2020

Antibacterial and antioxidant activities of traditional medicinal plants from the Erzurum region of Turkey.

Ir J Med Sci 2019 Nov 25;188(4):1303-1309. Epub 2019 Feb 25.

Faculty of Forestry, Department of Forest Industry Engineering, Kahramanmaras Sütcü Imam University, 46100, Kahramanmaraş, Turkey.

Background: In this study, 13 different extracts were investigated which are grown in the region of Erzurum.

Objective: The aim of this study was to screen various plant extracts that are known and used for medicinal purposes such as Ferula communis L., Rumex patientia L., Gundelia tournefortii L., Rheum ribes L., Asphodeline taurica, Polygonum arenastrum, Allium schoenoprasum L., and Ferula orientalis L.

Materials And Methods: Medicinal parts of plants such as leaves, flowers, and stems were investigated by 2,2-diphenyl-1-picrylhydrazyl, ferric reducing antioxidant power, and cupric reducing antioxidant capacity assays: Centaury and Blackthorn. Total phenolic content, total flavonoid content, and antimicrobial properties were also determined. Antibacterial and antifungal activities were investigated by the microdilution method and the agar diffusion method respectively.

Results: Accordingly, the results of the Rheum ribes L. plant have the highest antioxidant activity among all analyses made. But in almost all antioxidant analysis methods, the lowest antioxidant activity was found in Ferula orientalis L. According to the antibacterial analysis applied, it was found that the plant extracts were generally more effective on yeast strains than the test bacteria used; that is, most of the plants have antifungal effect.

Conclusions: Due to their antimicrobial, antifungal, and antioxidant properties, the extracts of these plants might be used as natural sources in the pharmaceutical and cosmetic industries.
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November 2019

Association of Monocyte-to-HDL Cholesterol Ratio with Slow Coronary Flow is Linked to Systemic Inflammation.

Clin Appl Thromb Hemost 2016 Jul 1;22(5):476-82. Epub 2015 Jul 1.

Turkiye Yuksek Ihtisas Training and Research Hospital, Cardiology Clinic, Ankara, Turkey.

Background: Previous studies proposed that both inflammation, oxidative stress, and impaired endothelial dysfunction have a significant role in occurrence of slow coronary flow (SCF). monocyte-to-high density lipoprotein cholesterol ratio (MHR) is a recently emerged indicator of inflammation and oxidative stress, which have been studied only in patients with chronic kidney disease.

Hypothesis: We aimed to assess the relationship between MHR and SCF.

Methods: Patients who had angiographically normal coronary arteries were enrolled in this retrospective study (n = 253 as SCF group and n = 176 as control group). Patients who had corrected thrombolysis in myocardial infarction frame counts (cTFCs) above the normal cutoffs were defined as with SCF.

Results: The MHR and high-sensitivity C-reactive protein (hsCRP) were significantly higher in the SCF group. In correlation analysis, MHR has a significantly positive correlation with cTFC and serum hsCRP levels (P < .001). In multivariate logistic regression analysis, MHR was found as independently associated with the presence of SCF (odds ratio: 1.24, P < .001).

Conclusion: Higher MHR which indicates an enhanced inflammation and oxidative stress was significantly and independently associated with the presence of SCF. Besides, MHR was positively correlated with serum hsCRP level as a conventional marker for systemic inflammation.
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July 2016