Sergio Roman-Roman

Sergio Roman-Roman

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Sergio Roman-Roman

Sergio Roman-Roman

Publications by authors named "Sergio Roman-Roman"

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66Publications

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Emerging Therapeutic Opportunities Based on Current Knowledge of Uveal Melanoma Biology.

Cancers (Basel) 2019 Jul 20;11(7). Epub 2019 Jul 20.

Uveal Melanoma Translational Group, Department of Translational Research, Institut Curie, PSL Research University, 75248 Paris, France.

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http://dx.doi.org/10.3390/cancers11071019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678734PMC
July 2019

Selumetinib-based therapy in uveal melanoma patient-derived xenografts.

Oncotarget 2018 Apr 24;9(31):21674-21686. Epub 2018 Apr 24.

Laboratory of Preclinical Investigation, Department of Translational Research, Institut Curie, PSL University Paris, Paris, France.

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http://dx.doi.org/10.18632/oncotarget.24670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955168PMC
April 2018

High-Throughput Drug Screening Identifies Pazopanib and Clofilium Tosylate as Promising Treatments for Malignant Rhabdoid Tumors.

Cell Rep 2017 Nov;21(7):1737-1745

Paris-Sciences-Lettres Research University, Institut Curie Research Center, SiRIC, Laboratory of Translational Research in Pediatric Oncology, Paris 75005, France; Paris-Sciences-Lettres Research University, Institut Curie Research Center, INSERM U830, Laboratory of Biology and Genetics of Cancers, Paris 75005, France; Paris-Sciences-Lettres Research University, Institut Curie Hospital, Department of Pediatric Oncology- Adolescents and Young Adults, Paris 75005, France. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.10.076DOI Listing
November 2017

Modeling tumor growth in the presence of a therapy with an effect on rate growth and variability by means of a modified Gompertz diffusion process.

J Theor Biol 2016 10 19;407:1-17. Epub 2016 Jul 19.

Dpto. de Estadística e Investigación Operativa, Universidad de Granada, Spain.

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http://dx.doi.org/10.1016/j.jtbi.2016.07.023DOI Listing
October 2016

Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status.

Nat Med 2016 06;22(6):577-8

Institut Curie, Paris Sciences et Lettres Research University, Paris, France.

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http://dx.doi.org/10.1038/nm.4098DOI Listing
June 2016

Upcoming translational challenges for uveal melanoma.

Br J Cancer 2015 Nov 27;113(9):1249-53. Epub 2015 Oct 27.

Department of Translational Research, Institut Curie, 26 rue d'Ulm, Paris 75005, France.

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http://dx.doi.org/10.1038/bjc.2015.269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815787PMC
November 2015

Stimulating translational research: several European life science institutions put their heads together.

Trends Mol Med 2015 Sep 5;21(9):525-7. Epub 2015 Aug 5.

EU-Life Translational Working Group; Centre for Genomic Regulation (CRG), Dr Aiguader 88, 08003 Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain.

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http://dx.doi.org/10.1016/j.molmed.2015.07.002DOI Listing
September 2015

Cancer molecular pathobiology in the clinics: concluding remarks.

Cancer Biomark 2014 ;14(2-3):195-6

Translational Research Department, Institut Curie, Paris, France. Tel.: +33 671 449193; E-mail:

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http://dx.doi.org/10.3233/CBM-130339DOI Listing
July 2015

Evaluating patient-derived colorectal cancer xenografts as preclinical models by comparison with patient clinical data.

Cancer Res 2015 Apr 24;75(8):1560-6. Epub 2015 Feb 24.

IFR71, Faculté de Sciences Biologiques et Pharmaceutiques, Université Paris Descartes, Sorbonne Paris Cité, Paris, France. Recherche Translationnelle, Centre de Recherche, Institut Curie, Paris, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-1590DOI Listing
April 2015

Estimating and determining the effect of a therapy on tumor dynamics by means of a modified Gompertz diffusion process.

J Theor Biol 2015 Jan 19;364:206-19. Epub 2014 Sep 19.

Dpto. de Estadística e Investigación Operativa, Universidad de Granada, Spain.

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http://dx.doi.org/10.1016/j.jtbi.2014.09.014DOI Listing
January 2015

Wnt signaling: a key regulator of bone mass.

Curr Top Dev Biol 2006 ;76:103-27

Yale University School of Medicine New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1016/S0070-2153(06)76004-5DOI Listing
January 2007

Wnt signalling pathway: a new target for the treatment of osteoporosis.

Expert Opin Ther Targets 2005 Oct;9(5):1063-77

Prostrakan Pharmaceuticals, 102 route de noisy, 93230 Romainville, France.

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http://dx.doi.org/10.1517/14728222.9.5.1063 DOI Listing
October 2005

AIP4 restricts transforming growth factor-beta signaling through a ubiquitination-independent mechanism.

J Biol Chem 2005 Jul 8;280(30):27645-53. Epub 2005 Jun 8.

INSERM U482, Hôpital Saint-Antoine, 184 Rue du Faubourg Saint-Antoine, 75571 Paris Cedex 12, France.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M500188200
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http://dx.doi.org/10.1074/jbc.M500188200DOI Listing
July 2005

Interaction between LRP5 and Frat1 mediates the activation of the Wnt canonical pathway.

J Biol Chem 2005 Apr 7;280(14):13616-23. Epub 2005 Feb 7.

Proskelia Pharmaceuticals, 102 route de Noisy, 93230 Romainville, France.

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http://dx.doi.org/10.1074/jbc.M411999200DOI Listing
April 2005

Murine Frizzled-1 behaves as an antagonist of the canonical Wnt/beta-catenin signaling.

J Biol Chem 2004 Feb 24;279(7):5725-33. Epub 2003 Nov 24.

ProSkelia Pharmaceuticals, 102 route de Noisy, 93230 Romainville, France..

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http://dx.doi.org/10.1074/jbc.M309233200DOI Listing
February 2004

BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by a Wnt autocrine loop.

J Bone Miner Res 2003 Oct;18(10):1842-53

Proskelia Pharmaceuticals, Romainville, France.

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http://dx.doi.org/10.1359/jbmr.2003.18.10.1842DOI Listing
October 2003