Sergio L Pereira

Sergio L Pereira

UNVERIFIED PROFILE

Are you Sergio L Pereira?   Register this Author

Register author
Sergio L Pereira

Sergio L Pereira

Publications by authors named "Sergio L Pereira"

Are you Sergio L Pereira?   Register this Author

22Publications

733Reads

34Profile Views

The CF Canada-Sick Kids Program in individual CF therapy: A resource for the advancement of personalized medicine in CF.

J Cyst Fibros 2019 01 10;18(1):35-43. Epub 2018 Oct 10.

Molecular Structure and Function, Hospital for Sick Children, Toronto, Canada; Department of Physiology, University of Toronto, Toronto, Canada; Department of Biochemistry, University of Toronto, Toronto, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcf.2018.03.013DOI Listing
January 2019

The Personal Genome Project Canada: findings from whole genome sequences of the inaugural 56 participants.

CMAJ 2018 02;190(5):E126-E136

The Centre for Applied Genomics (Reuter, Walker, Thiruvahindrapuram, Whitney, Yuen, Trost, Paton, Pereira, Herbrick, Wintle, Merico, Howe, MacDonald, Lu, Nalpathamkalam, Sung, Wang, Patel, Pellecchia, J. Wei, Strug, Bell, Kellam, Mahtani, Hosseini, Fiume, Marshall, Buchanan, Scherer); Divisions of Clinical Pharmacology and Toxicology (I. Cohn), or Clinical, and Metabolic Genetics (Sondheimer, Weksberg, Shuman, Bowdin, Meyn, Monfared), The Hospital for Sick Children; Departments of Paediatrics (Sondheimer, R. Cohn) and Molecular Genetics (Yuen, Weksberg, Shuman, R. Cohn, Ellis, Meyn), University of Toronto; Deep Genomics Inc. (Merico); Department of Psychiatry (Bassett), University Health Network and Centre for Addiction and Mental Health, University of Toronto; Li Ka Shing Knowledge Institute (Bombard), St. Michael's Hospital; Institute of Health Policy, Management and Evaluation (Bombard), University of Toronto; Centre for Genetic Medicine (Stavropoulos, Bowdin, Ray, Monfared); Molecular Genetics Laboratory (Stavropoulos, Ray, Marshall), Division of Genome Diagnostics, Paediatric Laboratory Medicine; Developmental and Stem Cell Biology (Hildebrandt, W. Wei, Romm, Pasceri, Ellis); Ted Rogers Cardiac Genome Clinic (Hosseini); Cytogenetics Laboratory (Joseph-George), Division of Genome Diagnostics, Paediatric Laboratory Medicine, The Hospital for Sick Children; Departments of Biochemistry and Laboratory Medicine, and Pathobiology (Keeley), University of Toronto; DNAstack (Cook, Fiume); McLaughlin Centre (Lee, Scherer), University of Toronto; Medcan Health Management Inc. (Davies, Hazell); Dalla Lana School of Public Health (Szego), Department of Family and Community Medicine, and The Joint Centre for Bioethics, University of Toronto; Centre for Clinical Ethics (Szego), St. Joseph's Health Centre, Toronto, Ont.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1503/cmaj.171151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798982PMC
February 2018

A Comprehensive Workflow for Read Depth-Based Identification of Copy-Number Variation from Whole-Genome Sequence Data.

Am J Hum Genet 2018 01;102(1):142-155

The Centre for Applied Genomics, Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; McLaughlin Centre, University of Toronto, Toronto, ON M5G 0A4, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2017.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777982PMC
January 2018

A microcosting and cost-consequence analysis of clinical genomic testing strategies in autism spectrum disorder.

Genet Med 2017 11 4;19(11):1268-1275. Epub 2017 May 4.

Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/gim.2017.47DOI Listing
November 2017

A homozygous mutation in the stem II domain of causes typical Roifman syndrome.

NPJ Genom Med 2017 10;2:23. Epub 2017 Jul 10.

Division of Immunology and Allergy, Department of Pediatrics, The Hospital for Sick Children and the University of Toronto, Toronto, ON Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41525-017-0024-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677950PMC
July 2017

Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder.

Nat Neurosci 2017 Apr 6;20(4):602-611. Epub 2017 Mar 6.

The Centre for Applied Genomics, Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nn.4524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501701PMC
April 2017

The genetic diversity of Epstein-Barr virus in the setting of transplantation relative to non-transplant settings: A feasibility study.

Pediatr Transplant 2016 Feb 18;20(1):124-9. Epub 2015 Nov 18.

Division of Infectious Diseases, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/petr.12610DOI Listing
February 2016

Fatal combined immunodeficiency associated with heterozygous mutation in STAT1.

J Allergy Clin Immunol 2014 Mar 13;133(3):807-17. Epub 2013 Nov 13.

Division of Immunology and Allergy, the Canadian Centre for Primary Immunodeficiency, the Jeffrey Modell Research Laboratory for the Diagnosis of Primary Immunodeficiency, the Hospital for Sick Children and the University of Toronto, Toronto, Canada; Canada-Israel Immunodeficiency Research Alliance, Toronto, Ontario, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2013.09.032DOI Listing
March 2014

The enigmatic monotypic crab plover Dromas ardeola is closely related to pratincoles and coursers (Aves, Charadriiformes, Glareolidae).

Genet Mol Biol 2010 Jul 1;33(3):583-6. Epub 2010 Sep 1.

Department of Natural History, Royal Ontario Museum, Toronto, ON Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/S1415-47572010000300033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036115PMC
July 2010

DNA evidence for a Paleocene origin of the Alcidae (Aves: Charadriiformes) in the Pacific and multiple dispersals across northern oceans.

Mol Phylogenet Evol 2008 Feb 5;46(2):430-45. Epub 2007 Dec 5.

Department of Natural History, Royal Ontario Museum, 100 Queen's Park Crescent, Toronto, Ont., Canada M5S 2C6.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ympev.2007.11.020DOI Listing
February 2008

Mitochondrial and nuclear DNA sequences support a Cretaceous origin of Columbiformes and a dispersal-driven radiation in the Paleocene .

Syst Biol 2007 Aug;56(4):656-72

Department of Natural History, Royal Ontario Museum, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/10635150701549672DOI Listing
August 2007

Phylogenetic relationships and divergence times of Charadriiformes genera: multigene evidence for the Cretaceous origin of at least 14 clades of shorebirds.

Biol Lett 2007 Apr;3(2):205-9

Department of Natural History, Royal Ontario Museum, 100 Queen's Park Crescent, Toronto, Ontario, Canada M5S 2C6.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1098/rsbl.2006.0606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375939PMC
April 2007

A mitogenomic timescale for birds detects variable phylogenetic rates of molecular evolution and refutes the standard molecular clock.

Mol Biol Evol 2006 Sep 14;23(9):1731-40. Epub 2006 Jun 14.

Department of Natural History, Royal Ontario Museum, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/molbev/msl038DOI Listing
September 2006

A molecular timescale for galliform birds accounting for uncertainty in time estimates and heterogeneity of rates of DNA substitutions across lineages and sites.

Mol Phylogenet Evol 2006 Feb 19;38(2):499-509. Epub 2005 Aug 19.

Department of Natural History, Royal Ontario Museum, 100 Queen's Park, Toronto, Ont., Canada M5S 2C6.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ympev.2005.07.007DOI Listing
February 2006

Molecular architecture and rates of DNA substitutions of the mitochondrial control region of cracid birds.

Genome 2004 Jun;47(3):535-45

Departamento de Biologia, Instituto de Biociências, Universidade de São Paulo, Brazil.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1139/g04-009DOI Listing
June 2004

Low number of mitochondrial pseudogenes in the chicken (Gallus gallus) nuclear genome: implications for molecular inference of population history and phylogenetics.

BMC Evol Biol 2004 Jun 25;4:17. Epub 2004 Jun 25.

Centre for Biodiversity and Conservation Biology - Royal Ontario Museum, Toronto, ON, M5S 2C6 Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2148-4-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC449702PMC
June 2004

Combined nuclear and mitochondrial DNA sequences resolve generic relationships within the Cracidae (Galliformes, Aves).

Syst Biol 2002 Dec;51(6):946-58

Departamento de Biologia, Universidade de São Paulo, Rua do Matão 277, Brazil 05508-900.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/10635150290102519DOI Listing
December 2002