Sergio E Baranzini

Sergio E Baranzini

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Sergio E Baranzini

Sergio E Baranzini

Publications by authors named "Sergio E Baranzini"

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Integrating biomedical research and electronic health records to create knowledge-based biologically meaningful machine-readable embeddings.

Nat Commun 2019 07 10;10(1):3045. Epub 2019 Jul 10.

Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1038/s41467-019-11069-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620318PMC
July 2019

Harnessing electronic medical records to advance research on multiple sclerosis.

Mult Scler 2019 03 9;25(3):408-418. Epub 2018 Jan 9.

MS Genetics, Department of Neurology, School of Medicine, University of California San Francisco (UCSF), San Francisco, CA, USA/Université de Nantes, INSERM, UMR 1064, ATIP-Avenir, Equipe 5 Centre de Recherche en Transplantation et Immunologie, Nantes, France.

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http://dx.doi.org/10.1177/1352458517747407DOI Listing
March 2019

Selective Estrogen Receptor Modulators Enhance CNS Remyelination Independent of Estrogen Receptors.

J Neurosci 2019 Mar 29;39(12):2184-2194. Epub 2019 Jan 29.

Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, California 94143, and

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http://dx.doi.org/10.1523/JNEUROSCI.1530-18.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433770PMC
March 2019

Insights into microbiome research 6: The role of consortia in studying the role of microbes in health and disease.

Mult Scler 2019 03;25(3):336-337

Department of Neurology, Weill Institute of Neuroscience, University of California, San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1177/1352458518811209DOI Listing
March 2019

Insights into microbiome research 5: Mapping is first but function must come next.

Mult Scler 2019 02;25(2):193-195

Sergio E Baranzini Weill Institute of Neuroscience, Department of Neurology. University of California San Francisco, USA.

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http://dx.doi.org/10.1177/1352458518811203DOI Listing
February 2019

Disease-modifying therapies alter gut microbial composition in MS.

Neurol Neuroimmunol Neuroinflamm 2019 01 26;6(1):e517. Epub 2018 Oct 26.

Department of Neurology (I.K.S., A.N., R.B., Y.B.), Department of Neuroscience (Y.Z., P.C.), and Department of Genetics & Genomic Sciences, Icahn Institute for Genomics & Multiscale Biology (J.C.C.), Icahn School of Medicine at Mount Sinai; Department of Neurology (E.C., E.C.-H., S.S., B.A.C.C., S.E.B.), Weill Institute for Neurosciences, University of California, San Francisco; E.C. is now with Universities Space Research Association, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA; Department of Pediatrics (J.D., R.K.), Department of Computer Science & Engineering (R.K.), and Center for Microbiome Innovation (R.K.), University of California, San Diego; and Neuroscience Initiative (P.C.), Advanced Research Science Center at the Graduate Center of the City University of New York.

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http://dx.doi.org/10.1212/NXI.0000000000000517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278850PMC
January 2019

Insights into microbiome research 4: The computational analysis.

Mult Scler 2019 01;25(1):21-22

Department of Neurology, Weill Institute of Neuroscience, University of California, San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1177/1352458518811205DOI Listing
January 2019

Protein network analysis reveals selectively vulnerable regions and biological processes in FTD.

Neurol Genet 2018 Oct 1;4(5):e266. Epub 2018 Oct 1.

Department of Neurology (L.W.B., N.Z.R.S., E.G.G., Z.A.M., B.L.M., W.W.S., J.S.Y.), Memory and Aging Center, University of California, San Francisco; Department of Psychiatry (C.M.K., N.W., A.O.-K.), Washington University, St. Louis, MO; School of Pharmacy (C.M., P.L.), University of Reading, Reading, UK; Laboratory of Neurogenetics (P.M.), Texas Tech University Health Science Center, Lubbock; Department of Molecular Neuroscience (C.M., J.H., P.L., R.F.), UCL Institute of Neurology, London, UK; Department of Radiology and Biomedical Imaging, Neuroradiology Section (C.P.H., R.S.D.), University of California, San Francisco; and Department of Neurology (S.E.B.), University of California, San Francisco.

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http://ng.neurology.org/lookup/doi/10.1212/NXG.0000000000000
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http://dx.doi.org/10.1212/NXG.0000000000000266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167176PMC
October 2018

Insights into microbiome research 2: Experimental design, sample collection, and shipment.

Mult Scler 2018 10;24(11):1419-1420

Weill Institute of Neuroscience, Department of Neurology, University of California San Francisco, San Francisco, CA, USA.

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http://journals.sagepub.com/doi/10.1177/1352458518788962
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http://dx.doi.org/10.1177/1352458518788962DOI Listing
October 2018

Insights into microbiome research 3: Who's there versus what are they doing?

Mult Scler 2018 10;24(12):1541-1542

Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1177/1352458518788974DOI Listing
October 2018

Insights into microbiome research 1: How to choose appropriate controls for a microbiome study in MS?

Mult Scler 2018 09;24(10):1278-1279

Department of Neurology, Weill Institute for Neurosciences, University of California-San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1177/1352458518788967DOI Listing
September 2018

Mononuclear cell transcriptome changes associated with dimethyl fumarate in MS.

Neurol Neuroimmunol Neuroinflamm 2018 Jul 12;5(4):e470. Epub 2018 Jun 12.

Division of Brain Sciences (A.R.G., M.T.C., R.N.), Department of Medicine, Imperial College London; the Department of Neurology (K.K.), Weill Institute for Neurosciences, University of California, San Francisco; icometrix (W.v.H.), Begaultlaan, Leuven, Belgium; the Department of Neurology (S.E.B.), Weill Institute for Neurosciences, Institute for Human Genetics and Graduate Program in Bioinformatics, University of California, San Francisco; and Division of Brain Sciences (P.M.M.), Department of Medicine, the Centre for Neurotechnology and the UK Dementia Research Institute, Imperial College London.

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http://nn.neurology.org/lookup/doi/10.1212/NXI.0000000000000
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http://dx.doi.org/10.1212/NXI.0000000000000470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168332PMC
July 2018

The microbiome and MS: The influence of the microbiota on MS risk and progression-Session chair summary.

Mult Scler 2018 04 2;24(5):587-589. Epub 2018 Mar 2.

Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1177/1352458518761167DOI Listing
April 2018

Multiple sclerosis.

Lancet 2018 04 23;391(10130):1622-1636. Epub 2018 Mar 23.

Queen Square MS Centre, UCL Institute of Neurology, London, UK; NIHR University College London Hospitals Biomedical Research Centre, London, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S01406736183048
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http://dx.doi.org/10.1016/S0140-6736(18)30481-1DOI Listing
April 2018

The era of GWAS is over - Commentary.

Mult Scler 2018 03 18;24(3):260-261. Epub 2017 Dec 18.

Department of Neurology, Institute for Human Genetics, University of California-San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1177/1352458517747408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834364PMC
March 2018

The Role of the Gut Microbiome in Multiple Sclerosis Risk and Progression: Towards Characterization of the "MS Microbiome".

Neurotherapeutics 2018 01;15(1):126-134

Department of Neurology and Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1007/s13311-017-0587-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794700PMC
January 2018

The Gut Microbiome in Neuromyelitis Optica.

Neurotherapeutics 2018 01;15(1):92-101

Department of Neurology, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1007/s13311-017-0594-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794705PMC
January 2018

The Genetics of Multiple Sclerosis: From 0 to 200 in 50 Years.

Trends Genet 2017 12 5;33(12):960-970. Epub 2017 Oct 5.

Weill Institute for Neurosciences. Department of Neurology, University of California San Francisco, San Francisco, CA, USA; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.tig.2017.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701819PMC
December 2017

Systematic integration of biomedical knowledge prioritizes drugs for repurposing.

Elife 2017 09 22;6. Epub 2017 Sep 22.

Biological and Medical Informatics Program, University of California, San Francisco, San Francisco, United States.

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http://dx.doi.org/10.7554/eLife.26726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640425PMC
September 2017

Gut microbiome analysis in neuromyelitis optica reveals overabundance of Clostridium perfringens.

Ann Neurol 2016 09 4;80(3):443-7. Epub 2016 Aug 4.

Department of Neurology, University of California, San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1002/ana.24718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053302PMC
September 2016

Immune cell-specific transcriptional profiling highlights distinct molecular pathways controlled by Tob1 upon experimental autoimmune encephalomyelitis.

Sci Rep 2016 08 22;6:31603. Epub 2016 Aug 22.

Department of Neurology, University of California San Francisco, San Francisco, California 94158, USA.

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http://dx.doi.org/10.1038/srep31603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992865PMC
August 2016

Association of HLA Genetic Risk Burden With Disease Phenotypes in Multiple Sclerosis.

JAMA Neurol 2016 07;73(7):795-802

Department of Neurology, School of Medicine, University of California, San Francisco5Bioengineering Graduate Group, University of California, San Francisco and Berkeley6Department of Radiology and Biomedical Imaging, University of California, San Francisc.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081075PMC
http://dx.doi.org/10.1001/jamaneurol.2016.0980DOI Listing
July 2016

Assessing the Power of Exome Chips.

PLoS One 2015 5;10(10):e0139642. Epub 2015 Oct 5.

Institute of Clinical Medicine, University of Oslo, 0316, Oslo, Norway; Department of Research, Cancer Registry of Norway, 0304, Oslo, Norway.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139642PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593624PMC
June 2016

iPINBPA: an integrative network-based functional module discovery tool for genome-wide association studies.

Pac Symp Biocomput 2015 :255-66

School of Computing, Queen's University, 25 Union Street, Goodwin Hall, Kingston, Ontario, K7L 3N6, Canada.

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April 2016

iCTNet2: integrating heterogeneous biological interactions to understand complex traits.

F1000Res 2015 5;4:485. Epub 2015 Aug 5.

Department of Neurology, University of California San Francisco, San Francisco, CA, 94158, USA; Graduate Program in Biological and Medical Informatics, University of California, San Francisco, San Francisco, CA, 94143-0523, USA.

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https://f1000research.com/articles/4-485/v2
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http://dx.doi.org/10.12688/f1000research.6836.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706053PMC
February 2016

Symposium 2-1  The autoimmunome: Similarities and differences among genetic susceptibility to common immune-related diseases.

Nihon Rinsho Meneki Gakkai Kaishi 2014 ;37(4):261

University of California, San Francisco.

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http://dx.doi.org/10.2177/jsci.37.261DOI Listing
January 2016

Heterogeneous Network Edge Prediction: A Data Integration Approach to Prioritize Disease-Associated Genes.

PLoS Comput Biol 2015 Jul 9;11(7):e1004259. Epub 2015 Jul 9.

Biological & Medical Informatics, University of California, San Francisco, San Francisco, California, United States of America; Department of Neurology, University of California, San Francisco, San Francisco, California, United States of America; Institute for Human Genetics, University of California, San Francisco, San Francisco, California, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1004259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497619PMC
July 2015

Genetic contribution to multiple sclerosis risk among Ashkenazi Jews.

BMC Med Genet 2015 Jul 28;16:55. Epub 2015 Jul 28.

Department of Neurology, University of California, San Francisco, 675 Nelson Rising Lane, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1186/s12881-015-0201-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557862PMC
July 2015

SNP imputation bias reduces effect size determination.

Front Genet 2015 9;6:30. Epub 2015 Feb 9.

Department of Neurology, University of California San Francisco San Francisco, CA, USA.

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http://dx.doi.org/10.3389/fgene.2015.00030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321633PMC
February 2015

PINBPA: cytoscape app for network analysis of GWAS data.

Bioinformatics 2015 Jan 25;31(2):262-4. Epub 2014 Sep 25.

School of Computing, Queen's University, 25 Union Street, Goodwin Hall, Kingston, Ontario K7L 3N6, Canada and Department of Neurology, University of California San Francisco, 675 Nelson Rising Lane, Room 215, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu644DOI Listing
January 2015

The role of antiproliferative gene Tob1 in the immune system.

Clin Exp Neuroimmunol 2014 Jun;5(2):132-136

University of California, San Francisco.

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http://dx.doi.org/10.1111/cen3.12125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111268PMC
June 2014

Astrocyte-encoded positional cues maintain sensorimotor circuit integrity.

Nature 2014 May 28;509(7499):189-94. Epub 2014 Apr 28.

1] Howard Hughes Medical Institute, University of California San Francisco, San Francisco, California 94143, USA [2] Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, California 94143, USA [3] Department of Pediatrics, University of California San Francisco, San Francisco, California 94143, USA [4] Department of Neurosurgery, University of California San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1038/nature13161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057936PMC
May 2014

Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer.

Nat Neurosci 2014 Apr 9;17(4):506-12. Epub 2014 Mar 9.

1] Department of Pediatrics, University of California, San Francisco (UCSF), San Francisco, California, USA. [2] Eli and Edythe Broad Institute for Stem Cell Research and Regeneration Medicine and Howard Hughes Medical Institute, UCSF, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nn.3676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975168PMC
April 2014

Gene expression profiling in MS: a fulfilled promise?

Mult Scler 2013 Dec;19(14):1813-4

Department of Neurology, University of California San Francisco (UCSF), San Francisco, USA.

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http://journals.sagepub.com/doi/10.1177/1352458513501573
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http://dx.doi.org/10.1177/1352458513501573DOI Listing
December 2013

Sequencing of the IL6 gene in a case-control study of cerebral palsy in children.

BMC Med Genet 2013 Dec 7;14:126. Epub 2013 Dec 7.

Department of Neurology, University of California, 675 Nelson Rising Lane, 94158, San Francisco, CA, USA.

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http://dx.doi.org/10.1186/1471-2350-14-126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881497PMC
December 2013

Dynamic, multi-level network models of clinical trials.

Pac Symp Biocomput 2011 :38-49

Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94110, USA.

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http://dx.doi.org/10.1142/9789814335058_0005DOI Listing
November 2013

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.

Authors:
Ashley H Beecham Nikolaos A Patsopoulos Dionysia K Xifara Mary F Davis Anu Kemppinen Chris Cotsapas Tejas S Shah Chris Spencer David Booth An Goris Annette Oturai Janna Saarela Bertrand Fontaine Bernhard Hemmer Claes Martin Frauke Zipp Sandra D'Alfonso Filippo Martinelli-Boneschi Bruce Taylor Hanne F Harbo Ingrid Kockum Jan Hillert Tomas Olsson Maria Ban Jorge R Oksenberg Rogier Hintzen Lisa F Barcellos Cristina Agliardi Lars Alfredsson Mehdi Alizadeh Carl Anderson Robert Andrews Helle Bach Søndergaard Amie Baker Gavin Band Sergio E Baranzini Nadia Barizzone Jeffrey Barrett Céline Bellenguez Laura Bergamaschi Luisa Bernardinelli Achim Berthele Viola Biberacher Thomas M C Binder Hannah Blackburn Izaura L Bomfim Paola Brambilla Simon Broadley Bruno Brochet Lou Brundin Dorothea Buck Helmut Butzkueven Stacy J Caillier William Camu Wassila Carpentier Paola Cavalla Elisabeth G Celius Irène Coman Giancarlo Comi Lucia Corrado Leentje Cosemans Isabelle Cournu-Rebeix Bruce A C Cree Daniele Cusi Vincent Damotte Gilles Defer Silvia R Delgado Panos Deloukas Alessia di Sapio Alexander T Dilthey Peter Donnelly Bénédicte Dubois Martin Duddy Sarah Edkins Irina Elovaara Federica Esposito Nikos Evangelou Barnaby Fiddes Judith Field Andre Franke Colin Freeman Irene Y Frohlich Daniela Galimberti Christian Gieger Pierre-Antoine Gourraud Christiane Graetz Andrew Graham Verena Grummel Clara Guaschino Athena Hadjixenofontos Hakon Hakonarson Christopher Halfpenny Gillian Hall Per Hall Anders Hamsten James Harley Timothy Harrower Clive Hawkins Garrett Hellenthal Charles Hillier Jeremy Hobart Muni Hoshi Sarah E Hunt Maja Jagodic Ilijas Jelčić Angela Jochim Brian Kendall Allan Kermode Trevor Kilpatrick Keijo Koivisto Ioanna Konidari Thomas Korn Helena Kronsbein Cordelia Langford Malin Larsson Mark Lathrop Christine Lebrun-Frenay Jeannette Lechner-Scott Michelle H Lee Maurizio A Leone Virpi Leppä Giuseppe Liberatore Benedicte A Lie Christina M Lill Magdalena Lindén Jenny Link Felix Luessi Jan Lycke Fabio Macciardi Satu Männistö Clara P Manrique Roland Martin Vittorio Martinelli Deborah Mason Gordon Mazibrada Cristin McCabe Inger-Lise Mero Julia Mescheriakova Loukas Moutsianas Kjell-Morten Myhr Guy Nagels Richard Nicholas Petra Nilsson Fredrik Piehl Matti Pirinen Siân E Price Hong Quach Mauri Reunanen Wim Robberecht Neil P Robertson Mariaemma Rodegher David Rog Marco Salvetti Nathalie C Schnetz-Boutaud Finn Sellebjerg Rebecca C Selter Catherine Schaefer Sandip Shaunak Ling Shen Simon Shields Volker Siffrin Mark Slee Per Soelberg Sorensen Melissa Sorosina Mireia Sospedra Anne Spurkland Amy Strange Emilie Sundqvist Vincent Thijs John Thorpe Anna Ticca Pentti Tienari Cornelia van Duijn Elizabeth M Visser Steve Vucic Helga Westerlind James S Wiley Alastair Wilkins James F Wilson Juliane Winkelmann John Zajicek Eva Zindler Jonathan L Haines Margaret A Pericak-Vance Adrian J Ivinson Graeme Stewart David Hafler Stephen L Hauser Alastair Compston Gil McVean Philip De Jager Stephen J Sawcer Jacob L McCauley

Nat Genet 2013 Nov 29;45(11):1353-60. Epub 2013 Sep 29.

1] John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA. [2].

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http://dx.doi.org/10.1038/ng.2770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832895PMC
November 2013

A genome-wide association study of brain lesion distribution in multiple sclerosis.

Brain 2013 Apr 13;136(Pt 4):1012-24. Epub 2013 Feb 13.

Department of Neurology, School of Medicine, University of California, San Francisco, 675 Nelson Rising Lane, Suite 215, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1093/brain/aws363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613709PMC
April 2013

In depth comparison of an individual's DNA and its lymphoblastoid cell line using whole genome sequencing.

BMC Genomics 2012 Sep 14;13:477. Epub 2012 Sep 14.

Department of Neurology, University of California San Francisco, San Francisco, CA 94143-0435, USA.

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http://dx.doi.org/10.1186/1471-2164-13-477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473256PMC
September 2012

The genetics of multiple sclerosis: an up-to-date review.

Immunol Rev 2012 Jul;248(1):87-103

Department of Neurology, University of California San Francisco, San Francisco, CA 94143-0435, USA.

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http://dx.doi.org/10.1111/j.1600-065X.2012.01134.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967887PMC
July 2012

Genetics of multiple sclerosis: swimming in an ocean of data.

Curr Opin Neurol 2012 Jun;25(3):239-45

Department of Neurology, University of California, San Francisco, California, USA.

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http://dx.doi.org/10.1097/WCO.0b013e3283533a93DOI Listing
June 2012

Myelin regeneration: a recapitulation of development?

Annu Rev Neurosci 2011 ;34:21-43

Departments of Pediatrics and Neurosurgery, Eli and Edyth Broad Institute for Stem Cell Research and Regeneration Medicine and Howard Hughes Medical Institute, University of California, San Francisco, California 94143, USA.

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http://www.annualreviews.org/doi/10.1146/annurev-neuro-06101
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http://dx.doi.org/10.1146/annurev-neuro-061010-113629DOI Listing
October 2011

iCTNet: a Cytoscape plugin to produce and analyze integrative complex traits networks.

BMC Bioinformatics 2011 Sep 26;12:380. Epub 2011 Sep 26.

School of Computing, Queen’s University, 25 Union Street, Goodwin Hall, Kingston, Ontario K7L 3N6, Canada.

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http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/1471-2105-12-380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190406PMC
September 2011

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

Authors:
Stephen Sawcer Garrett Hellenthal Matti Pirinen Chris C A Spencer Nikolaos A Patsopoulos Loukas Moutsianas Alexander Dilthey Zhan Su Colin Freeman Sarah E Hunt Sarah Edkins Emma Gray David R Booth Simon C Potter An Goris Gavin Band Annette Bang Oturai Amy Strange Janna Saarela Céline Bellenguez Bertrand Fontaine Matthew Gillman Bernhard Hemmer Rhian Gwilliam Frauke Zipp Alagurevathi Jayakumar Roland Martin Stephen Leslie Stanley Hawkins Eleni Giannoulatou Sandra D'alfonso Hannah Blackburn Filippo Martinelli Boneschi Jennifer Liddle Hanne F Harbo Marc L Perez Anne Spurkland Matthew J Waller Marcin P Mycko Michelle Ricketts Manuel Comabella Naomi Hammond Ingrid Kockum Owen T McCann Maria Ban Pamela Whittaker Anu Kemppinen Paul Weston Clive Hawkins Sara Widaa John Zajicek Serge Dronov Neil Robertson Suzannah J Bumpstead Lisa F Barcellos Rathi Ravindrarajah Roby Abraham Lars Alfredsson Kristin Ardlie Cristin Aubin Amie Baker Katharine Baker Sergio E Baranzini Laura Bergamaschi Roberto Bergamaschi Allan Bernstein Achim Berthele Mike Boggild Jonathan P Bradfield David Brassat Simon A Broadley Dorothea Buck Helmut Butzkueven Ruggero Capra William M Carroll Paola Cavalla Elisabeth G Celius Sabine Cepok Rosetta Chiavacci Françoise Clerget-Darpoux Katleen Clysters Giancarlo Comi Mark Cossburn Isabelle Cournu-Rebeix Mathew B Cox Wendy Cozen Bruce A C Cree Anne H Cross Daniele Cusi Mark J Daly Emma Davis Paul I W de Bakker Marc Debouverie Marie Beatrice D'hooghe Katherine Dixon Rita Dobosi Bénédicte Dubois David Ellinghaus Irina Elovaara Federica Esposito Claire Fontenille Simon Foote Andre Franke Daniela Galimberti Angelo Ghezzi Joseph Glessner Refujia Gomez Olivier Gout Colin Graham Struan F A Grant Franca Rosa Guerini Hakon Hakonarson Per Hall Anders Hamsten Hans-Peter Hartung Rob N Heard Simon Heath Jeremy Hobart Muna Hoshi Carmen Infante-Duarte Gillian Ingram Wendy Ingram Talat Islam Maja Jagodic Michael Kabesch Allan G Kermode Trevor J Kilpatrick Cecilia Kim Norman Klopp Keijo Koivisto Malin Larsson Mark Lathrop Jeannette S Lechner-Scott Maurizio A Leone Virpi Leppä Ulrika Liljedahl Izaura Lima Bomfim Robin R Lincoln Jenny Link Jianjun Liu Aslaug R Lorentzen Sara Lupoli Fabio Macciardi Thomas Mack Mark Marriott Vittorio Martinelli Deborah Mason Jacob L McCauley Frank Mentch Inger-Lise Mero Tania Mihalova Xavier Montalban John Mottershead Kjell-Morten Myhr Paola Naldi William Ollier Alison Page Aarno Palotie Jean Pelletier Laura Piccio Trevor Pickersgill Fredrik Piehl Susan Pobywajlo Hong L Quach Patricia P Ramsay Mauri Reunanen Richard Reynolds John D Rioux Mariaemma Rodegher Sabine Roesner Justin P Rubio Ina-Maria Rückert Marco Salvetti Erika Salvi Adam Santaniello Catherine A Schaefer Stefan Schreiber Christian Schulze Rodney J Scott Finn Sellebjerg Krzysztof W Selmaj David Sexton Ling Shen Brigid Simms-Acuna Sheila Skidmore Patrick M A Sleiman Cathrine Smestad Per Soelberg Sørensen Helle Bach Søndergaard Jim Stankovich Richard C Strange Anna-Maija Sulonen Emilie Sundqvist Ann-Christine Syvänen Francesca Taddeo Bruce Taylor Jenefer M Blackwell Pentti Tienari Elvira Bramon Ayman Tourbah Matthew A Brown Ewa Tronczynska Juan P Casas Niall Tubridy Aiden Corvin Jane Vickery Janusz Jankowski Pablo Villoslada Hugh S Markus Kai Wang Christopher G Mathew James Wason Colin N A Palmer H-Erich Wichmann Robert Plomin Ernest Willoughby Anna Rautanen Juliane Winkelmann Michael Wittig Richard C Trembath Jacqueline Yaouanq Ananth C Viswanathan Haitao Zhang Nicholas W Wood Rebecca Zuvich Panos Deloukas Cordelia Langford Audrey Duncanson Jorge R Oksenberg Margaret A Pericak-Vance Jonathan L Haines Tomas Olsson Jan Hillert Adrian J Ivinson Philip L De Jager Leena Peltonen Graeme J Stewart David A Hafler Stephen L Hauser Gil McVean Peter Donnelly Alastair Compston

Nature 2011 Aug 10;476(7359):214-9. Epub 2011 Aug 10.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182531PMC
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Revealing the genetic basis of multiple sclerosis: are we there yet?

Curr Opin Genet Dev 2011 Jun 17;21(3):317-24. Epub 2011 Jan 17.

Department of Neurology, School of Medicine, University of California San Francisco, 513 Parnassus Ave., Room S-256, San Francisco, CA 94143-0435, United States.

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Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis.

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Department of Neurology, School of Medicine, University of California-San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143-0435, USA.

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Multiple sclerosis genetics--is the glass half full, or half empty?

Nat Rev Neurol 2010 Aug 13;6(8):429-37. Epub 2010 Jul 13.

Department of Neurology, School of Medicine, University of California at San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143-0435, USA.

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http://www.nature.com/articles/nrneurol.2010.91
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The genetics of autoimmune diseases: a networked perspective.

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Department of Neurology, School of Medicine, University of California San Francisco, 513 Parnassus Ave. Room S-256, San Francisco, CA 94143-0435, USA.

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Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS.

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Institute for Regeneration Medicine, Howard Hughes Medical Institute, University of California at San Francisco, San Francisco, California 94143, USA.

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Pathway and network-based analysis of genome-wide association studies in multiple sclerosis.

Hum Mol Genet 2009 Jun 13;18(11):2078-90. Epub 2009 Mar 13.

Department of Neurology, School of Medicine, University of California San Francisco, 513 Parnassus Ave. Room S-256, San Francisco, CA 94143-0435, USA.

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http://dx.doi.org/10.1093/hmg/ddp120DOI Listing
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Changes in matrix metalloproteinases and their inhibitors during interferon-beta treatment in multiple sclerosis.

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February 2009

Systems biology and its application to the understanding of neurological diseases.

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Department of Neuroscience, Hospital Clinic-Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.

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http://dx.doi.org/10.1002/ana.21634DOI Listing
February 2009

The genetics of multiple sclerosis: SNPs to pathways to pathogenesis.

Nat Rev Genet 2008 Jul 10;9(7):516-26. Epub 2008 Jun 10.

Department of Neurology, School of Medicine, University of California at San Francisco, 513 Parnassus Avenue, San Francisco, California 94143-0435, USA.

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Evidence for association of chromosome 10 open reading frame (C10orf27) gene polymorphisms and multiple sclerosis.

Mult Scler 2008 Apr 21;14(3):412-4. Epub 2008 Jan 21.

Unitat de Neuroimmunologia Clínica, Hospital Universitari Vall d'Hebron (HUVH), 08035 Barcelona, Spain.

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http://dx.doi.org/10.1177/1352458507083780DOI Listing
April 2008

Genome-wide pharmacogenomic analysis of the response to interferon beta therapy in multiple sclerosis.

Arch Neurol 2008 Mar 14;65(3):337-44. Epub 2008 Jan 14.

Department of Neurology, University of California, San Francisco, San Francisco, CA 94143-0435, USA.

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http://dx.doi.org/10.1001/archneurol.2008.47DOI Listing
March 2008

Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets.

Nature 2008 Feb 17;451(7182):1076-81. Epub 2008 Feb 17.

Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA.

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February 2008

Quantitative longitudinal analysis of T cell receptor repertoire expression in HIV-infected patients on antiretroviral and interleukin-2 therapy.

AIDS Res Hum Retroviruses 2007 May;23(5):741-7

Department of Neurology University of California at San Francisco, California 94143, USA.

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May 2007

Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity.

J Exp Med 2007 Feb 29;204(2):321-30. Epub 2007 Jan 29.

Department of Neurology and Neurological Studies, and 2Department of Pathology, Stanford University Medical Center, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1084/jem.20061839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118721PMC
February 2007

Systems-based medicine approaches to understand and treat complex diseases. The example of multiple sclerosis.

Autoimmunity 2006 Dec;39(8):651-62

Department of Neurology, School of Medicine, University of California, San Francisco, 513 Parnassus Avenue Room S-256, San Francisco, CA 94143-0435, USA.

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December 2006

Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis.

Hum Mol Genet 2006 Sep 11;15(18):2813-24. Epub 2006 Aug 11.

Division of Epidemiology, School of Public Health, University of California, Berkeley 94720, USA, and Department of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, UK.

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September 2006

Mapping gene activity in complex disorders: Integration of expression and genomic scans for multiple sclerosis.

J Neuroimmunol 2005 Oct;167(1-2):157-69

Department of Neurology, School of Medicine, University of California, 513 Parnassus Avenue, S-256, San Francisco, CA 94143-0435, USA.

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October 2005