Sergio Bernardini

Sergio Bernardini

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Sergio Bernardini

Publications by authors named "Sergio Bernardini"

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Serum or plasma? An old question looking for new answers.

Clin Chem Lab Med 2020 Jan;58(2):178-187

Dipartimento di Medicina di Laboratorio e Anatomia Patologica Azienda Ospedaliera Universitaria e USL di Modena, Modena, Italy.

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http://dx.doi.org/10.1515/cclm-2019-0719DOI Listing
January 2020

Cerebrospinal Fluid Orexin Levels and Nocturnal Sleep Disruption in Alzheimer's Disease Patients Showing Neuropsychiatric Symptoms.

J Alzheimers Dis 2018 ;66(3):993-999

Department of Systems Medicine, Sleep Medicine Centre, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.3233/JAD-180769DOI Listing
November 2019

Total laboratory automation has the potential to be the field of application of artificial intelligence: the cyber-physical system and "Automation 4.0".

Clin Chem Lab Med 2019 Oct;57(11):e279-e281

Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1515/cclm-2019-0226DOI Listing
October 2019

Alzheimer's disease: Making the point.

Clin Biochem 2019 Oct 21;72:1-2. Epub 2019 May 21.

Institute of Medical Chemistry and Laboratory Medicine, The First Faculty of Medicine, General University Hospital, U Nemocnice 2 CZ-121 08, Prague 2, Czech republic.

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http://dx.doi.org/10.1016/j.clinbiochem.2019.05.007DOI Listing
October 2019

The standardization of cerebrospinal fluid markers and neuropathological diagnoses brings to light the frequent complexity of concomitant pathology in Alzheimer's disease: The next challenge for biochemical markers?

Clin Biochem 2019 Oct 10;72:15-23. Epub 2019 Jun 10.

Institut de Pathologie Est -Neuropathologie, Hospices civils de Lyon, Lyon, France; University Claude Bernard Lyon 1, Lyon, France; Department of Cancer Cell Plasticity, Cancer Research Centre of Lyon, INSERM U1052, CNRS UMR5286, Lyon, France. Electronic address:

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http://dx.doi.org/10.1016/j.clinbiochem.2019.06.004DOI Listing
October 2019

AD biomarker discovery in CSF and in alternative matrices.

Clin Biochem 2019 Oct 19;72:52-57. Epub 2019 Aug 19.

Dept. Experimental Medicine, University of Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1016/j.clinbiochem.2019.08.008DOI Listing
October 2019

A Hazelnut-Enriched Diet Modulates Oxidative Stress and Inflammation Gene Expression without Weight Gain.

Oxid Med Cell Longev 2019 4;2019:4683723. Epub 2019 Jul 4.

Department of Medical and Surgical Sciences, University of Magna Græcia, Viale Europa, Germaneto, 88100 Catanzaro, Italy.

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http://dx.doi.org/10.1155/2019/4683723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637671PMC
July 2019

The circulating miRNAs as diagnostic and prognostic markers.

Clin Chem Lab Med 2019 Jun;57(7):932-953

Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1515/cclm-2018-0838DOI Listing
June 2019

Position paper on laboratory testing for patients with haemophilia. A consensus document from SISET, AICE, SIBioC and SIPMeL.

Blood Transfus 2019 05 4;17(3):229-236. Epub 2019 Feb 4.

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Haemophilia and Thrombosis Center and Fondazione Luigi Villa, Milan, Italy.

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http://dx.doi.org/10.2450/2019.0241-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596380PMC
May 2019

CSF α-synuclein inversely correlates with non-motor symptoms in a cohort of PD patients.

Parkinsonism Relat Disord 2019 04 15;61:203-206. Epub 2018 Oct 15.

Department of Systems Medicine, University of Roma Tor Vergata, Rome, Italy; IRCCS Fondazione Santa Lucia, Rome, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S13538020183045
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http://dx.doi.org/10.1016/j.parkreldis.2018.10.018DOI Listing
April 2019

Obstructive sleep apnea may induce orexinergic system and cerebral β-amyloid metabolism dysregulation: is it a further proof for Alzheimer's disease risk?

Sleep Med 2019 04 11;56:171-176. Epub 2019 Jan 11.

Sleep Medicine Centre, Neurophysiopathology Unit, Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1016/j.sleep.2019.01.003DOI Listing
April 2019

Association between physical activity and dementia's risk factors in patients with Parkinson's disease.

J Neural Transm (Vienna) 2019 03 12;126(3):319-325. Epub 2019 Feb 12.

Department of Systems Medicine, University of Roma "Tor Vergata", Via Montpellier 1, 00135, Rome, Italy.

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http://dx.doi.org/10.1007/s00702-019-01979-0DOI Listing
March 2019

Successful long-term therapy with flecainide in a family with paramyotonia congenita.

J Neurol Neurosurg Psychiatry 2018 11 27;89(11):1232-1234. Epub 2018 Feb 27.

Department of Medicine, Surgery, Neurology, Metabolic and Aging Science, Reference Center for Neurological and Neuromuscular Rare Disease, Università degli Studi della Campania Luigi Vanvitelli, Napoli, Campania, Italy.

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http://jnnp.bmj.com/lookup/doi/10.1136/jnnp-2017-317615
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http://dx.doi.org/10.1136/jnnp-2017-317615DOI Listing
November 2018

Nephelometric assay of urine free light chains: an alternative and early clinical test for Bence-Jones protein quantification.

Clin Chem Lab Med 2018 11;56(12):e313-e315

Department of Experimental Medicine and Surgery, "Tor Vergata" University Hospital, Rome, Italy.

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http://dx.doi.org/10.1515/cclm-2018-0402DOI Listing
November 2018

Multiple Sclerosis: kFLC index values related to gender.

Mult Scler Relat Disord 2018 Nov 30;26:58-60. Epub 2018 Aug 30.

Department of Experimental Medicine and Surgery, "Tor Vergata" University Hospital, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2018.08.018DOI Listing
November 2018

Long story short: an introduction to the short-term and longterm Six Sigma quality and its importance in laboratory medicine for the management of extra-analytical processes.

Clin Chem Lab Med 2018 10;56(11):1838-1845

Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1515/cclm-2018-0310DOI Listing
October 2018

Alzheimer's disease in the omics era.

Clin Biochem 2018 Sep 18;59:9-16. Epub 2018 Jun 18.

Tor Vergata University General Hospital, Dept. Experimental Medicine, Rome, Italy.

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http://dx.doi.org/10.1016/j.clinbiochem.2018.06.011DOI Listing
September 2018

Clinical value of CSF amyloid-beta-42 and tau proteins in Progressive Supranuclear Palsy.

J Neural Transm (Vienna) 2018 09 14;125(9):1373-1379. Epub 2018 Jun 14.

Department of Systems Medicine, University of Roma Tor Vergata, Viale Oxford 1, 00139, Rome, Italy.

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http://dx.doi.org/10.1007/s00702-018-1893-1DOI Listing
September 2018

New HPLC instrument performance evaluation in HbA determination and comparison with capillary electrophoresis.

Scand J Clin Lab Invest 2018 Sep 11;78(5):393-397. Epub 2018 Jul 11.

a Department of Experimental Medicine and Surgery , "Tor Vergata" University Hospital , Rome , Italy.

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http://dx.doi.org/10.1080/00365513.2018.1487072DOI Listing
September 2018

Diagnosis of neurodegenerative dementia: where do we stand, now?

Ann Transl Med 2018 Sep;6(17):340

Department of Experimental Medicine, Tor Vergata University General Hospital, Rome, Italy.

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http://atm.amegroups.com/article/view/21001/20747
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http://dx.doi.org/10.21037/atm.2018.08.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174181PMC
September 2018

Vacuolated PAS-positive lymphocytes as an hallmark of Pompe disease and other myopathies related to impaired autophagy.

J Cell Physiol 2018 08 22;233(8):5829-5837. Epub 2018 Feb 22.

2nd Division of Neurology, Department of Medicine, Surgery, Neurology, Metabolic and Aging Science, Reference Center for Neurological and Neuromuscular Rare Disease & Interuniversity Center for Research in Neurosciences, University of Campania "Luigi Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.1002/jcp.26365DOI Listing
August 2018

Levamisole in Illicit Trafficking Cocaine Seized: A One-Year Study.

J Psychoactive Drugs 2017 Nov-Dec;49(5):408-412. Epub 2017 Aug 16.

h Associate Professor, Department of Biomedicine and Prevention, Section of Legal Medicine, Social Security and Forensic Toxicology , University of Rome Tor Vergata , Rome , Italy.

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http://dx.doi.org/10.1080/02791072.2017.1361558DOI Listing
July 2018

Severe insulin resistance in disguise: A familial case of reactive hypoglycemia associated with a novel heterozygous INSR mutation.

Pediatr Diabetes 2018 06 7;19(4):670-674. Epub 2018 Feb 7.

Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1111/pedi.12632DOI Listing
June 2018

Validation of the Six Sigma Z-score for the quality assessment of clinical laboratory timeliness.

Clin Chem Lab Med 2018 03;56(4):595-601

Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1515/cclm-2017-0642DOI Listing
March 2018

Sleep apnoeas may represent a reversible risk factor for amyloid-β pathology.

Brain 2017 12;140(12):e75

Sleep Medicine Centre, Neurophysiopathology Unit, Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1093/brain/awx281DOI Listing
December 2017

Hypothalamic dysfunction is related to sleep impairment and CSF biomarkers in Alzheimer's disease.

J Neurol 2017 Nov 12;264(11):2215-2223. Epub 2017 Sep 12.

Sleep Medicine Centre, Neurophysiopathology Unit, Department of Systems Medicine, University of Rome "Tor Vergata", Viale Oxford 81, 00133, Rome, Italy.

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http://dx.doi.org/10.1007/s00415-017-8613-xDOI Listing
November 2017

Complement system dysregulation in patients affected by Idiopathic Generalized Epilepsy and the effect of antiepileptic treatment.

Epilepsy Res 2017 11 21;137:107-111. Epub 2017 Sep 21.

Sleep Medicine Centre, Neurophysiopathology Unit, Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy; IRCCS Fondazione Santa Lucia, Rome, Italy.

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http://dx.doi.org/10.1016/j.eplepsyres.2017.09.005DOI Listing
November 2017

Local vibration inhibits H-reflex but does not compromise manual dexterity and does not increase tremor.

Hum Mov Sci 2017 Oct 1;55:221-228. Epub 2017 Sep 1.

Department of Movement, Human and Health Sciences, University of Rome Foro Italico, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S01679457173022
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http://dx.doi.org/10.1016/j.humov.2017.08.018DOI Listing
October 2017

An LC-MS Assay with Isocratic Separation and On-line Solid Phase Extraction to Improve the Routine Therapeutic Drug Monitoring of Busulfan in Plasma.

J Med Biochem 2017 Apr 22;36(2):113-121. Epub 2017 Apr 22.

Department of Laboratory Medicine, Tor Vergata University Hospital of Rome, Rome, Italy.

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http://dx.doi.org/10.1515/jomb-2016-0031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471643PMC
April 2017

Adherence to the Mediterranean diet is inversely associated with metabolic syndrome occurrence: a meta-analysis of observational studies.

Int J Food Sci Nutr 2017 Mar 25;68(2):138-148. Epub 2016 Aug 25.

e Department of Preventive Medicine & Public Health, School of Medicine , University of Navarra-IDISNA , Pamplona , Spain.

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http://dx.doi.org/10.1080/09637486.2016.1221900DOI Listing
March 2017

Artificial Neural Network for Total Laboratory Automation to Improve the Management of Sample Dilution.

SLAS Technol 2017 02 10;22(1):44-49. Epub 2016 Jul 10.

1 Department of Laboratory Medicine, Tor Vergata University Hospital of Rome, Rome, Italy.

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http://dx.doi.org/10.1177/2211068216636635DOI Listing
February 2017

Mediterranean meal versus Western meal effects on postprandial ox-LDL, oxidative and inflammatory gene expression in healthy subjects: a randomized controlled trial for nutrigenomic approach in cardiometabolic risk.

Acta Diabetol 2017 Feb 5;54(2):141-149. Epub 2016 Oct 5.

Division of Clinical Nutrition and Nutrigenomics, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133, Rome, Italy.

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http://dx.doi.org/10.1007/s00592-016-0917-2DOI Listing
February 2017

Cutaneous features of myotonic dystrophy types 1 and 2: Implication of premature aging and vitamin D homeostasis.

Neuromuscul Disord 2017 Feb 16;27(2):163-169. Epub 2016 Nov 16.

Department of Systems Medicine, Division of Neurology, University of Rome Tor Vergata, Viale Oxford 81, 00133 Rome, Italy; Department of Experimental Medicine and Surgery, Division of Clinical Biochemistry, University of Rome Tor Vergata, Viale Oxford 81, 00133 Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.nmd.2016.11.004DOI Listing
February 2017

Preanalytical investigations of phlebotomy: methodological aspects, pitfalls and recommendations.

Biochem Med (Zagreb) 2017 Feb;27(1):177-191

Laboratory Medicine Department, "Tor Vergata" University Hospital, Rome, Italy; Experimental Medicine and Surgery Department, "Tor Vergata" University, Rome, Italy.

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http://dx.doi.org/10.11613/BM.2017.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382842PMC
February 2017

Minimal tumour burden in haematological diseases: a step forward with quantitative assessment of Bence-Jones in nephelometry?

Br J Haematol 2016 11 18;175(4):733-735. Epub 2015 Dec 18.

Department of Experimental Medicine and Surgery, "Tor Vergata" University, Rome, Italy.

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http://dx.doi.org/10.1111/bjh.13878DOI Listing
November 2016

Antinuclear autoantibodies and pregnancy outcome in women with unexplained recurrent miscarriage.

Am J Reprod Immunol 2016 11 12;76(5):396-399. Epub 2016 Sep 12.

Department of Obstetrics and Gynecology, Catholic University of Sacred Heart, Rome, Italy.

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http://dx.doi.org/10.1111/aji.12560DOI Listing
November 2016

How many biomarkers to discriminate neurodegenerative dementia?

Crit Rev Clin Lab Sci 2015 17;52(6):314-26. Epub 2015 Aug 17.

b Department of Experimental Medicine and Surgery , Tor Vergata University of Rome , Rome , Italy.

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http://dx.doi.org/10.3109/10408363.2015.1051658DOI Listing
August 2016

Functional impairment of activated protein C in breast cancer - relationship to survival outcomes.

Am J Cancer Res 2016 1;6(6):1450-7. Epub 2016 Jun 1.

San Raffaele Roma Open UniversityVia di Val Cannuta 247, 00166 Rome, Italy; Interinstitutional Multidisciplinary Biobank (BioBIM), IRCCS San Raffaele PisanaVia di Val Cannuta 247, 00166 Rome, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937746PMC
July 2016

Total Automation for the Core Laboratory: Improving the Turnaround Time Helps to Reduce the Volume of Ordered STAT Tests.

J Lab Autom 2016 Jun 16;21(3):451-8. Epub 2015 Apr 16.

Department of Laboratory Medicine, Tor Vergata University Hospital of Rome, Rome, Italy Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1177/2211068215581488DOI Listing
June 2016

Phlebotomy, a bridge between laboratory and patient.

Biochem Med (Zagreb) 2016 ;26(1):17-33

Laboratory Medicine Department, "Tor Vergata" University Hospital, Rome, Italy; Experimental Medicine and Surgery Department, "Tor Vergata" University, Rome, Italy.

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http://dx.doi.org/10.11613/BM.2016.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783087PMC
May 2016

Hyperglucagonemia in an animal model of insulin- deficient diabetes: what therapy can improve it?

Clin Diabetes Endocrinol 2016 2;2:11. Epub 2016 May 2.

Division of Metabolism, Endocrinology & Diabetes, University of Michigan Medical Center, Ann Arbor, MI USA.

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http://dx.doi.org/10.1186/s40842-016-0029-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471666PMC
May 2016

Beta-amyloid and phosphorylated tau metabolism changes in narcolepsy over time.

Sleep Breath 2016 Mar 23;20(1):277-83; discussion 283. Epub 2016 Jan 23.

Department of Systems Medicine, Neurophysiopathology Unit, Sleep Medicine Centre, University of Rome 'Tor Vergata', Viale Oxford 81, 00133, Rome, Italy.

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http://dx.doi.org/10.1007/s11325-015-1305-9DOI Listing
March 2016

Auto-reactions, autoimmunity and psoriatic arthritis.

Autoimmun Rev 2015 Dec 5;14(12):1142-6. Epub 2015 Aug 5.

Rheumatology, Allergology and Clinical Immunology, Department of "Medicina dei Sistemi", University of Rome Tor Vergata, Rome, Italy; Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Rome, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15689972150016
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http://dx.doi.org/10.1016/j.autrev.2015.08.003DOI Listing
December 2015

Dietary fat overload reprograms brown fat mitochondria.

Front Physiol 2015 29;6:272. Epub 2015 Sep 29.

Department of Biology, University of Rome "Tor Vergata," Rome, Italy ; IRCCS San Raffaele Roma Rome, Italy.

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http://dx.doi.org/10.3389/fphys.2015.00272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586425PMC
October 2015

Role of amyloid-β CSF levels in cognitive deficit in MS.

Clin Chim Acta 2015 Sep 7;449:23-30. Epub 2015 Feb 7.

IRCCS Fondazione Santa Lucia/Centro Europeo per la Ricerca sul Cervello (CERC), 00143 Rome, Italy; Dipartimento di Medicina dei Sistemi, Università Tor Vergata, 00133 Rome, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00098981150005
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http://dx.doi.org/10.1016/j.cca.2015.01.035DOI Listing
September 2015

The IFCC-Siemens Specialized Conference: Biomarkers in neuropsychiatric disorders.

Clin Chim Acta 2015 Sep 25;449:1-2. Epub 2015 Jun 25.

Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Italy.

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http://dx.doi.org/10.1016/j.cca.2015.06.018DOI Listing
September 2015

MicroRNA expression is dysregulated in narcolepsy: a new evidence?

Sleep Med 2015 Aug 22;16(8):1027-8. Epub 2015 Apr 22.

Sleep Medicine Centre, Neurophysiopathology Unit, Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1016/j.sleep.2015.03.016DOI Listing
August 2015

Glutathione Decrement Drives Thermogenic Program In Adipose Cells.

Sci Rep 2015 Aug 11;5:13091. Epub 2015 Aug 11.

1] Dept. Biology, University of Rome "Tor Vergata", Via della Ricerca Scientifica 1, 00133 Rome, Italy [2] Scientific Institute for Research Hospitalization and Health Care and Università Telematica San Raffaele Roma, Via di Val Cannuta 247, 00166 Rome, Italy.

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http://dx.doi.org/10.1038/srep13091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531326PMC
August 2015

Lithium/Valproic acid combination and L-glutamate induce similar pattern of changes in the expression of miR-30a-5p in SH-SY5Y neuroblastoma cells.

Neuromolecular Med 2014 Dec 23;16(4):872-7. Epub 2014 Aug 23.

Department of Clinical and Behavioural Neurology, IRCCS Santa Lucia Foundation, 00179, Rome, Italy.

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http://link.springer.com/10.1007/s12017-014-8325-7
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http://dx.doi.org/10.1007/s12017-014-8325-7DOI Listing
December 2014

May CSF beta-amyloid and tau proteins levels be influenced by long treatment duration and stable medication in narcolepsy?

Sleep Med 2014 Nov 8;15(11):1424. Epub 2014 Jul 8.

Department of Systems Medicine, Neurophysiopathology Unit, Sleep Medicine Centre, University of Rome 'Tor Vergata', Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.sleep.2014.07.002DOI Listing
November 2014

Direct analytical sample quality assessment for biomarker investigation: qualifying cerebrospinal fluid samples.

Proteomics 2014 Sep 8;14(17-18):1954-62. Epub 2014 Aug 8.

Department of Experimental Medicine and Surgery, University of Rome "Tor Vergata", Rome, Italy; IRCCS-Santa Lucia Foundation, Rome, Italy.

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http://dx.doi.org/10.1002/pmic.201300565DOI Listing
September 2014

The effect of neuropeptide Y on cell survival and neurotrophin expression in in-vitro models of Alzheimer's disease.

Can J Physiol Pharmacol 2014 Aug 13;92(8):621-30. Epub 2014 Jun 13.

a Department of Clinical and Behavioural Neurology, IRCCS Santa Lucia Foundation, Via Ardeatina 354, 00142 Rome, Italy.

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http://dx.doi.org/10.1139/cjpp-2014-0099DOI Listing
August 2014

CRBP-1 expression in ovarian cancer: a potential therapeutic target.

Anticancer Res 2014 Jul;34(7):3303-12

Anatomic Pathology, Department of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy

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July 2014