Sergey Leikin

Sergey Leikin

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Sergey Leikin

Sergey Leikin

Publications by authors named "Sergey Leikin"

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Evidence of biomechanical and collagen heterogeneity in uterine fibroids.

PLoS One 2019 29;14(4):e0215646. Epub 2019 Apr 29.

Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215646PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488189PMC
January 2020

COL1A1 C-propeptide mutations cause ER mislocalization of procollagen and impair C-terminal procollagen processing.

Biochim Biophys Acta Mol Basis Dis 2019 Sep 2;1865(9):2210-2223. Epub 2019 May 2.

Section of Heritable Disorders of Bone and Extracellular Matrix, NICHD, NIH, Bethesda, MD, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2019.04.018DOI Listing
September 2019

Endoplasmic reticulum stress is induced in growth plate hypertrophic chondrocytes in G610C mouse model of osteogenesis imperfecta.

Biochem Biophys Res Commun 2019 01 20;509(1):235-240. Epub 2018 Dec 20.

Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD, 21201, USA; Center for Childhood Cancer and Blood Diseases, The Research Institute at Nationwide Children's Hospital, Columbus, OH, 43205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.12.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370306PMC
January 2019

Noncanonical autophagy at ER exit sites regulates procollagen turnover.

Proc Natl Acad Sci U S A 2018 10 4;115(43):E10099-E10108. Epub 2018 Oct 4.

Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1814552115
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http://dx.doi.org/10.1073/pnas.1814552115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205486PMC
October 2018

Celecoxib treatment of fibrous dysplasia (FD) in a human FD cell line and FD-like lesions in mice with protein kinase A (PKA) defects.

Mol Cell Endocrinol 2017 01 4;439:165-174. Epub 2016 Aug 4.

Section on Endocrinology and Genetics (SEGEN), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2016.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123938PMC
January 2017

Osteoblast Malfunction Caused by Cell Stress Response to Procollagen Misfolding in α2(I)-G610C Mouse Model of Osteogenesis Imperfecta.

J Bone Miner Res 2016 08 13;31(8):1608-1616. Epub 2016 Apr 13.

Section on Physical Biochemistry, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health, Bethesda, MD 20892.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061462PMC
http://dx.doi.org/10.1002/jbmr.2824DOI Listing
August 2016

Haploinsufficiency for either one of the type-II regulatory subunits of protein kinase A improves the bone phenotype of Prkar1a+/- mice.

Hum Mol Genet 2015 Nov 5;24(21):6080-92. Epub 2015 Aug 5.

Section on Endocrinology and Genetics (SEGEN), Program on Developmental Endocrinology & Genetics (PDEGEN), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD),

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http://dx.doi.org/10.1093/hmg/ddv320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599668PMC
November 2015

Pulse-chase analysis of procollagen biosynthesis by azidohomoalanine labeling.

Connect Tissue Res 2014 Oct-Dec;55(5-6):403-10. Epub 2014 Sep 22.

Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health , Bethesda, MD , USA and.

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http://dx.doi.org/10.3109/03008207.2014.959120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254658PMC
July 2015

Collagen degradation by tumor-associated trypsins.

Arch Biochem Biophys 2013 Jul 28;535(2):111-4. Epub 2013 Mar 28.

National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.abb.2013.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683366PMC
July 2013

Helical structure determines different susceptibilities of dsDNA, dsRNA, and tsDNA to counterion-induced condensation.

Biophys J 2013 May;104(9):2031-41

Department of Chemistry, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1016/j.bpj.2013.03.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647158PMC
May 2013

Absence of FKBP10 in recessive type XI osteogenesis imperfecta leads to diminished collagen cross-linking and reduced collagen deposition in extracellular matrix.

Hum Mutat 2012 Nov 16;33(11):1589-98. Epub 2012 Jul 16.

Bone and Extracellular Matrix Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1002/humu.22139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470738PMC
November 2012

Electrostatic braiding and homologous pairing of DNA double helices.

Biophys J 2011 Aug;101(4):875-84

Department of Chemistry, Imperial College London, London, UK.

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http://dx.doi.org/10.1016/j.bpj.2011.06.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175075PMC
August 2011

Chaperoning osteogenesis: new protein-folding disease paradigms.

Trends Cell Biol 2011 Mar 21;21(3):168-76. Epub 2010 Dec 21.

Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.tcb.2010.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057343PMC
March 2011

Molecular mechanism of type I collagen homotrimer resistance to mammalian collagenases.

J Biol Chem 2010 Jul 12;285(29):22276-81. Epub 2010 May 12.

Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1074/jbc.M110.102079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903388PMC
July 2010

Carcinomas contain a matrix metalloproteinase-resistant isoform of type I collagen exerting selective support to invasion.

Cancer Res 2010 Jun 11;70(11):4366-74. Epub 2010 May 11.

Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Building 9, Room1N-111, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-4057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880213PMC
June 2010

Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone.

Proc Natl Acad Sci U S A 2010 May 26;107(19):8683-8. Epub 2010 Apr 26.

Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics and Pediatric Endocrinology Inter-institute Training Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.pnas.org/content/107/19/8683.full.pdf
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http://www.pnas.org/cgi/doi/10.1073/pnas.1003680107
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http://dx.doi.org/10.1073/pnas.1003680107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889322PMC
May 2010

Lack of cyclophilin B in osteogenesis imperfecta with normal collagen folding.

N Engl J Med 2010 Feb 20;362(6):521-8. Epub 2010 Jan 20.

National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1056/NEJMoa0907705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156560PMC
February 2010

Segregation of type I collagen homo- and heterotrimers in fibrils.

J Mol Biol 2008 Oct 9;383(1):122-32. Epub 2008 Aug 9.

Section on Physical Biochemistry, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD 20892, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00222836080098
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http://dx.doi.org/10.1016/j.jmb.2008.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839200PMC
October 2008

Helical coherence of DNA in crystals and solution.

Nucleic Acids Res 2008 Oct 28;36(17):5540-51. Epub 2008 Aug 28.

Institut für Theoretische Physik II: Weiche Materie, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, D-40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1093/nar/gkn514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553576PMC
October 2008

Structural heterogeneity of type I collagen triple helix and its role in osteogenesis imperfecta.

J Biol Chem 2008 Feb 11;283(8):4787-98. Epub 2007 Dec 11.

Section on Physical Biochemistry, Bone and Extracellular Matrix Branch, NICHD, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1074/jbc.M705773200DOI Listing
February 2008

DNA double helices recognize mutual sequence homology in a protein free environment.

J Phys Chem B 2008 Jan 9;112(4):1060-4. Epub 2008 Jan 9.

Division of Molecular Biosciences, Department of Chemistry, Imperial College London, SW7 2AZ London, UK.

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http://dx.doi.org/10.1021/jp7112297DOI Listing
January 2008

Selective retention and degradation of molecules with a single mutant alpha1(I) chain in the Brtl IV mouse model of OI.

Matrix Biol 2007 Oct 27;26(8):604-14. Epub 2007 Jun 27.

Department of Biochemistry "A. Castellani", University of Pavia, Via Taramelli 3B, 27100 Pavia, Italy.

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http://dx.doi.org/10.1016/j.matbio.2007.06.005DOI Listing
October 2007

Procollagen triple helix assembly: an unconventional chaperone-assisted folding paradigm.

PLoS One 2007 Oct 10;2(10):e1029. Epub 2007 Oct 10.

Section on Physical Biochemistry, Department of Health and Human Services, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0001029PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000351PMC
October 2007

Prolyl 3-hydroxylase 1 deficiency causes a recessive metabolic bone disorder resembling lethal/severe osteogenesis imperfecta.

Nat Genet 2007 Mar 4;39(3):359-65. Epub 2007 Feb 4.

Bone and Extracellular Matrix Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/ng1968DOI Listing
March 2007

Molecular mechanism of alpha 1(I)-osteogenesis imperfecta/Ehlers-Danlos syndrome: unfolding of an N-anchor domain at the N-terminal end of the type I collagen triple helix.

J Biol Chem 2006 Mar 5;281(10):6463-70. Epub 2006 Jan 5.

Section on Physical Biochemistry, NICHD, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1074/jbc.M511830200DOI Listing
March 2006

Direct observation of azimuthal correlations between DNA in hydrated aggregates.

Phys Rev Lett 2005 Sep 29;95(14):148102. Epub 2005 Sep 29.

Department of Chemistry, Imperial College London, SW7 2AZ London, United Kingdom.

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http://dx.doi.org/10.1103/PhysRevLett.95.148102DOI Listing
September 2005

Mutations near amino end of alpha1(I) collagen cause combined osteogenesis imperfecta/Ehlers-Danlos syndrome by interference with N-propeptide processing.

J Biol Chem 2005 May 22;280(19):19259-69. Epub 2005 Feb 22.

Bone and Extracellular Matrix Branch, NICHD, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1074/jbc.M414698200DOI Listing
May 2005

Interactions of inorganic phosphate and sulfate anions with collagen.

Biochemistry 2004 Nov;43(47):14901-12

National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Building 9, Room 1E125, Bethesda, Maryland 20892-0924, USA.

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http://dx.doi.org/10.1021/bi048788bDOI Listing
November 2004

Structure, stability and interactions of type I collagen with GLY349-CYS substitution in alpha 1(I) chain in a murine Osteogenesis Imperfecta model.

Matrix Biol 2004 May;23(2):101-12

Section on Physical Biochemistry, National Institute of Child Health and Human Development, National Institutes of Health, Bldg. 9, Rm. 1E-127, Bethesda, MD 20892, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0945053X0400029
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http://dx.doi.org/10.1016/j.matbio.2004.03.002DOI Listing
May 2004

Changes in thermal stability and microunfolding pattern of collagen helix resulting from the loss of alpha2(I) chain in osteogenesis imperfecta murine.

J Mol Biol 2003 Aug;331(1):191-200

National Institute of Child Health and Human Development, NIH, DHHS, Building 9, Room 1E-125, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/s0022-2836(03)00715-0DOI Listing
August 2003